• Title/Summary/Keyword: P-base

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항생제 다제내성균 Staphylococcus aureus SA2로부터 분리한 테트라사이클린 내성 플라스미드 pKH6의 염기서열

  • Lee, Dae-Woon;Yoon, Sung-Joon;Kim, Woo-Koo;Shin, Chul-Kyo;Im, Sung-Hwan;Lee, Baek-Rak;Moon, Kyung-Ho
    • Microbiology and Biotechnology Letters
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    • v.24 no.4
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    • pp.423-426
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    • 1996
  • The complete nucleotide sequence of pKH6, a tetracycline-resistance (Tc$^{r}$) plasmid isolated from multi-drug resistant Staphylococcus aureus SA2, has been determined and compared with that of the staphylococcal Tc$^{r}$ plasmid pTl8l. The nucleotide sequences of the two plasmids are in agreement except for 7 nucleotides. All differences are caused by base pair substitutions. Among 6 substitutions, 3 occurred in coding regions. However, only two base substitutions in coding regions resulted in changes of amino acid sequences in two different ORFs of repC and Pre proteins.

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ON THE HOMOLOGY OF THE MODULI SPACE OF $G_2$ INSTANTONS

  • Park, Young-Gi
    • Communications of the Korean Mathematical Society
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    • v.9 no.4
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    • pp.933-944
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    • 1994
  • Let $\pi : P \to S^4$ be a principal G-bundle over $S^4$ whose the structure group G is a compact, connected, simple Lie group. Since $\pi_3(G) = \pi_4 (BG) = Z$, we can classify the principal bundle $P_k$ over $S^4$ by the map $S^4 \to BG$ of degree k. Atiyah and Jones [2] showed that $C_k = A_k/g^b_k$ is homotopy equivalent to $\Omega^3_k G \simeq \Omega^4_k BG$ where $A_k$ is the space of the all connections in $P_k$ and $g^b_k$ is the based gauge group which consists of all base point preserving automorphisms on $P_k$. Here $\Omega^nX$ is the space of all base-point preserving continuous map from $S^n$ to X. Let $M_k$ be the space of based gauge equivalence classes of all connections in $P_k$ satisfying the Yang-Mills self-duality equations, which we call the moduli space of G instantons.

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Kinetics Studies on the Mechanism of Hydrolysis of S-Phenyl-S-vinyl-N-p-tosylsulfilimine Derivatives

  • Pyun, Sang-Yong;Kim, Tae-Rin;Lee, Chong-Ryoul;Kim, Whan-Gi
    • Bulletin of the Korean Chemical Society
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    • v.24 no.3
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    • pp.306-310
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    • 2003
  • Hydrolysis reactions of S-phenyl-S-vinyl-N-p-tosylsulfilimine (VSI) and its derivatives at various pH have been investigated kinetically. The hydrolysis reactions produced phenylvinylsulfoxide and p-toluene sulfonamide as the products. The reactions are first order and Hammett ρ values for pH 1.0, 6.0, and 11.0 are 0.82, 0.45, and 0.57, respectively. This reaction is not catalyzed by general base. The plot of k vs pH shows that there are three different regions of the rate constants $(k_t)$ in the profile.; At pH < 2 and pH > 10, the rate constants are directly proportional to the concentrations of hydronium and hydroxide ion catalyzed reactions, respectively. The rate constant remains nearly the same at 2 < pH < 10. On the bases of these results, the plausible hydrolysis mechanism and a rate equation have been proposed: At pH < 2.0, the reaction proceeds via the addition of water molecule to sulfur after protonation at the nitrogen atom of the sulfilimine, whereas at pH > 10.0, the reaction proceeds by the addition of hydroxide ion to sulfur directly. In the range of pH 2.0-10.0, the addition of water to sulfur of sulfilimine appears to be the rate controlling step.

Effect of Sling-Applied Plank Exercise on the Muscular Frequency, Stiffness, Decrement of the Rectus Abdominis and Longissimus of the Trunk according to the Stability of the Base of Support (지지면의 안정성에 따른 슬링적용 플랭크 운동이 몸통 배곧은근과 가장긴근의 근긴장도, 근경직도, 근탄성도에 미치는 영향)

  • Jung-Gyu Yoon
    • PNF and Movement
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    • v.22 no.2
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    • pp.181-189
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    • 2024
  • Purpose: This study aimed to identify the effect of sling-applied plank exercise on the frequency, stiffness, and decrement of the rectus abdominis and longissimus muscles of the trunk according to the stability of the base of support. Methods: Thirty-three young adults volunteered to participate and were randomly assigned to one of three groups (SS, stable support; LES, lower extremity support; and ULES, upper and lower extremity support) according to the stability of the base of support. The muscular properties of the rectus abdominis and longissimus muscles during sling-assisted plank exercise according to the stability of the base of support. were measured by using Myoton PRO (Myoton AS, Tallinn, Estonia). Statistical analysis was performed MANOVA to determine the effect of sling-assisted plank exercise on the muscular properties of the rectus abdominis and longissimus muscles according to the stability of the base of support. Post hoc analysis was conducted using Bonferroni. The level of statistical significance was set at α = 0.05. Results: When comparing the muscular properties, the muscle frequency and stiffness of the left rectus abdominis of ULES were significantly decreased compared to that of SS (p < 0.05). In the measurement time, the muscle frequency and the muscle stiffness of the right rectus abdominis increased significantly after the intervention (p < 0.05). Conclusion: It was concluded that the more unstable the base of support (ULES), the higher the exercise strength, and the muscle frequency and stiffness decreased on the rectus abdominis at rest.

Impact of ZrO2 nanoparticles addition on flexural properties of denture base resin with different thickness

  • Albasarah, Sara;Al Abdulghani, Hanan;Alaseef, Nawarah;al-Qarni, Faisal D.;Akhtar, Sultan;Khan, Soban Q.;Ateeq, Ijlal Shahrukh;Gad, Mohammed M.
    • The Journal of Advanced Prosthodontics
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    • v.13 no.4
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    • pp.226-236
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    • 2021
  • PURPOSE. This study aimed to evaluate the effect of incorporating zirconium oxide nanoparticles (nano-ZrO2) in polymethylmethacrylate (PMMA) denture base resin on flexural properties at different material thicknesses. MATERIALS AND METHODS. Heat polymerized acrylic resin specimens (N = 120) were fabricated and divided into 4 groups according to denture base thickness (2.5 mm, 2.0 mm, 1.5 mm, 1.0 mm). Each group was subdivided into 3 subgroups (n = 10) according to nano-ZrO2 concentration (0%, 2.5%, and 5%). Flexural strength and elastic modulus were evaluated using a three-point bending test. One-way ANOVA, Tukey's post hoc, and two-way ANOVA were used for data analysis (α = .05). Scanning electron microscopy (SEM) was used for fracture surface analysis and nanoparticles distributions. RESULTS. Groups with 0% nano-ZrO2 showed no significant difference in the flexural strength as thickness decreased (P = .153). The addition of nano-zirconia significantly increased the flexural strength (P < .001). The highest value was with 5% nano-ZrO2 and 2 mm-thickness (125.4 ± 18.3 MPa), followed by 5% nano-ZrO2 and 1.5 mm-thickness (110.3 ± 8.5 MPa). Moreover, the effect of various concentration levels on elastic modulus was statistically significant for 2 mm thickness (P = .001), but the combined effect of thickness and concentration on elastic modulus was insignificant (P = .10). CONCLUSION. Reinforcement of denture base material with nano-ZrO2 significantly increased flexural strength and modulus of elasticity. Reducing material thickness did not decrease flexural strength when nano-ZrO2 was incorporated. In clinical practice, when low thickness of denture base material is indicated, PMMA/nano-ZrO2 could be used with minimum acceptable thickness of 1.5 mm.

Effects of cultivation ages and modes on microbial diversity in the rhizosphere soil of Panax ginseng

  • Xiao, Chunping;Yang, Limin;Zhang, Lianxue;Liu, Cuijing;Han, Mei
    • Journal of Ginseng Research
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    • v.40 no.1
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    • pp.28-37
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    • 2016
  • Background: Panax ginseng cannot be cultivated on the same land consecutively for an extended period, and the underlying mechanism regarding microorganisms is still being explored. Methods: Polymerase chain reaction and denaturing gradient gel electrophoresis (PCR-DGGE) and BIO-LOG methods were used to evaluate the microbial genetic and functional diversity associated with the P. ginseng rhizosphere soil in various cultivation ages and modes. Results: The analysis of microbial diversity using PCR-DGGE showed that microbial communities were significantly variable in composition, of which six bacterial phyla and seven fungal classes were detected in P. ginseng soil. Among them, Proteobacteria and Hypocreales dominated. Fusarium oxysporum, a soilborne pathogen, was found in all P. ginseng soil samples except R0. The results from functional diversity suggested that the microbial metabolic diversity of fallow soil abandoned in 2003was the maximum and transplanted soil was higher than direct-seeding soil and the forest soil uncultivated P. ginseng, whereas the increase in cultivation ages in the same mode led to decreases in microbial diversity in P. ginseng soil. Carbohydrates, amino acids, and polymers were the main carbon sources utilized. Furthermore, the microbial diversity index and multivariate comparisons indicated that the augmentation of P. ginseng cultivation ages resulted in decreased bacterial diversity and increased fungal diversity, whereas microbial diversity was improved strikingly in transplanted soil and fallow soil abandoned for at least one decade. Conclusion: The key factors for discontinuous P. ginseng cultivation were the lack of balance in rhizosphere microbial communities and the outbreak of soilborne diseases caused by the accumulation of its root exudates.

Experimental Assessment of Forest Soil Sensitivity to Acidification -Application of Prediction Models for Acid Neutralization Responses- (산림토양(山林土壤)의 산성화(酸性化) 민감도(敏感度)에 대(對)한 실험적(實驗的) 평가(評價)(I) -산중화(酸中和) 반응(反應) 예측모형(豫測模型)의 활용(活用)-)

  • Lee, Seung Woo;Park, Gwan Soo
    • Journal of Korean Society of Forest Science
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    • v.90 no.1
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    • pp.133-138
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    • 2001
  • Increased base cation loss and Al mobilization, a consequence of soil acid neutralization responses, are common in air polluted areas showing forest decline. The prediction models of acid neutralization responses were developed by using indicators of soil acidification level(pH, and base saturation) in order to assess the forest soil sensitivity to acidification. The soil acidification level was greatest in Namsan followed by Kanghwa, Ulsan, and Hongcheon, being contrary to regional total $ANC_H$ pattern through soil columns leached with additional acid ($16.7mmol_c\;H^+/kg$), Both base exchange and Al dissolution were main acid neutralization processes in all study regions. There were low base exchange and high Al dissolution in the regions of the low total $ANC_H$. The $ANC_M$ by sulfate adsorption was greatest in Hongcheon compared with other regions even though the AN rate was very low as 6.4%. Coefficients of adjusted determination of simple and multiple regression models between soil acidification level indicators and the acid neutralization responses were more than 0.52(p<0.04) and 0.89(p<0.01), respectively. The result suggests that soil pH and base saturation are available indicators for predicting the acid neutralization responses. These prediction models could be used as an useful method to measure forest soil sensitivity to acidification.

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A COMPARATIVE STUDY ON THE DIMENSIONAL CHANGE OF THE DIFFERENT DENTURE BASES

  • Kim, Myung-Joo;Kim, Chang-Whe
    • The Journal of Korean Academy of Prosthodontics
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    • v.44 no.6
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    • pp.712-721
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    • 2006
  • Statement of problem. Acrylic resin is most commonly used for denture bases. However, acrylic resin has week points of volumetric shrinkage during polymerization that reduces denture fit. The expandability of POSS (Polyhedral Oligomeric Silsesquioxane) containing polymer could be expected to reduce the polymerization shrinkage of denture bases and would increase the adaptability of the denture to the tissue. Purpose. The purpose of this study was to compare the dimensional stability in the conventional acrylic resin base, POSS-containing acrylic resin base, and metal bases. Materials and methods. Thirty six maxillary edentulous casts and dentures of different base were fabricated. Tooth movement and tissue contour change of denture after processing (resin curing, deflasking, decasting and finishing without polishing) and immersion in artificial saliva at $37^{\circ}C$ for 1 week and 4 weeks were measured using digital measuring microscope and threedimensional laser scanner. Results. The results were as follows: 1. The conventional resin group showed significant (p<0.01) dimensional change throughout the procedure (processing and immersion in artificial saliva). 2. After processing, the metal group and POSS resin group showed lower linear and 3-dimensional change than conventional resin group (p<0.01). 3. There was no statistically significant linear and 3-dimensional change after immersion for 1 week and 4 weeks in metal and POSS resin group. 4. In all groups, the midline and alveolar ridge crest area presented smaller 3-dimensional change compared with vestibule and posterior palatal seal area after processing and soaking in artificial saliva for 1 week and 4 weeks (p<0.01). Conclusion. In this study, a reinforced acrylic-based resin with POSS showed good dimensional stability.

A Study on the Processing Conditions of Younsa (연사의 조리 과학적 연구)

  • 김종한;김태홍
    • Korean journal of food and cookery science
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    • v.2 no.1
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    • pp.59-64
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    • 1986
  • This study was designed to revive the disappeared Younsa and to investigate the optimum processing condition and characteristics of Younsa nade of the glutinous rice powder. Agitating time of base mixture, thickness of Younsa base, and frying time were examined as the influencing factors in Younsa processings. The textural parameters of Younsa were determined by sensory cvaluation and hardness of Younsa was measured by Rheometer. The results were found as follows; 1. In the sensory evaluation, 1) The Younsa base agitated for 10 minutes by agitating machine was favorable. It, however, did not showed any significant difference among products prepared under varying agitaing time-10 minutes, 20 minutes, and 30 minutes. (p<0.05) 2) The thinnest Younsa base (5 cm$\times$4cm, 1.1-1.5g) showed the most favorable quality and the second quality went to 5cm$\times$4cm, 1.6-2.0g, the third 5cm$\times$4cm, 2.1-2.5g, the fourth 5 cm$\times$4 cm, 2.6-3.0g. (p<0.05) 3) In examination of varying frying time, the optimal time for frying Younsa was 12 minutes was 12 minutes in $150 ^{\circ}C$. However, the quality was found no significant difference between 12 minutes's fried Younsa and 14 minutes's. (p<0.05). 2. The hardness of the most favorable Younsa, agitated for 10 minutes, the thinnest (5 cm$\times$4 cm, 1.1-1.5g), ana fried for 12 minutes in $150^{\circ}C$ was 0.59-0.73 kg/wt measured by Rheometer. The thickest Younsa base (5 cm$\times$4 cm, 2.6-3.0g) is the hardest (1.26 kg/wt). The most optimal conditions in this experiment were found the same ones which was written in historical literature.

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Quality Assessment of Film Processing Chemicals in Dentistry (치과에서 사용되는 필름 현상액에 대한 품질 평가 연구)

  • Han Mi-Ra;Kang Byung-Cheol
    • Journal of Korean Academy of Oral and Maxillofacial Radiology
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    • v.29 no.1
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    • pp.299-308
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    • 1999
  • Purpose: The purpose of this study was to compare the qualities of the four different processing chemicals (solutions). Materials and Methods: With EP 21 films(Ektaspeed plus film, Kodak Co., USA), nine unexposed and nine exposed films of a step wedge were processed utilizing automatic film processor(XR 24, Durr Co., Germany) for 5 days. During 5 days, the total number of processed films including out-patient' s intraoral films were about 400-500 for each brand. Base plus fog density, film density, contrast of processed films were measured with densitometer(model 07-443 digital densitometer, Victoreen Co., USA). These measurements were analyzed for comparison. Results: The results were as follows, 1. For the base plus fog density. there was significant difference among the four chemicals (p<0.05). The sequence of the base plus fog densities was in ascending order by Kodak, X-dol 90. Agfa and Konica. 2. For the film density. all chemicals showed useful range of photographic densities(0.25-2.5). The sequence of the film densities was in ascending order by Kodak, X-dol 90, Konica and Agfa. But there was no statistically significant difference of film density between X-dol and Kodak (p<0.05). 3. The sequence of the contrasts was in ascending order by Konica, X-dol 90, Kodak and Agfa. But there was no statistically significant difference of contrast between X-dol and Konica (p<0.05). Conclusion: These results indicated that the four processing chemicals had clinically useful film density and contrast. but only Kodak processing chemical had useful base plus fog density.

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