• The Korean Journal of Pain
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• 제30권4호
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• pp.296-303
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• 2017

Background: To achieve a prolonged therapeutic effect in patients with lumbar facet joint syndrome, radiofrequency medial branch neurotomy (RF-MB) is commonly performed. The purpose of this study was to evaluate the prognostic value of paravertebral muscle twitching when performing RF-MB in patients with lumbar facet joint syndrome. Methods: We collected and analyzed data from 68 patients with confirmed facet joint syndrome. Sensory stimulation was performed at 50 Hz with a 0.5 V cut-off value. Patients were divided into 3 groups according to the twitching of the paravertebral muscle during 2 Hz motor stimulation: 'Complete', when twitching was observed at all needles; 'Partial', when twitching was present at 1 or 2 needles; and 'None', when no twitching was observed. The relationship between the long-term effects of RF-MB and paravertebral muscle twitching was analyzed. Results: The mean effect duration of RF-MB was 4.6, 5.8, and 7.0 months in the None, Partial, and Complete groups, respectively (P = 0.47). Although the mean effect duration of RF-MB did not increase significantly in proportion to the paravertebral muscle twitching, the Complete group had prolonged effect duration (> 6 months) than the None group in subgroup analysis. (P = 0.03). Conclusions: Paravertebral muscle twitching while performing lumbar RF-MB may be a reliable predictor of long-term efficacy when sensory provocation under 0.5 V is achieved. However, further investigation may be necessary for clarifying its clinical significance.

• Asian Pacific Journal of Cancer Prevention
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• 제13권4호
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• pp.1321-1324
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• 2012

Background: DNA polymerase beta ($pol{\beta}$) is a key enzyme in the base excision repair pathway. It is 39kDa protein, with two subunits, one large subunit of 31 kDa having catalytic activity between exon V to exon XIV, and an 8 kDa smaller subunit having single strand DNA binding activity. Exons V to VII have double strand DNA binding activity, whereas exons VIII to XI account for the nucleotidyl transferase activity and exons XII to XIV the dNTP selection activity. Aim: To examine the association between $pol{\beta}$ polymorphisms and the risk of ovarian cancer, the present case control study was performed using 152 cancer samples and non-metastatic normal samples from the same patients. In this study, mutational analysis of $pol{\beta}$ genomic DNA was undertaken using primers from exons IX to XIV - the portion having catalytic activity. Results: We detected alteration in DNA polymerase beta by SSCP. Two specific heterozygous point mutations of $pol{\beta}$ were identified in Exon 9:486, A->C (polymorphism 1; 11.18%) and in Exon 11:676, A->C (polymorphism 2; 9.86%). The correlation study involving polymorphism 1 and 4 types of tissue showed a significant correlation between mucinous type with a Pearson correlation value of 4.03 (p=0.04). The association among polymorphism 2 with serous type and stage IV together have shown Pearson ${\chi}^2$ value of 3.28 with likelihood ratio of 4.4 (p=0.07) with OR =2.08 (0.3-14.55). This indicates that there is a tendency of correlation among polymorphism 2, serous type and stage IV, indicating a risk factor for ovarian cancer. Conclusion: Hence, the results indicate that there is a tendency for $pol{\beta}$ polymorphisms being a risk factor for ovarian carcinogenesis in India.

• 수산해양기술연구
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• 제20권2호
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• pp.137-142
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• 1984

수평관내 증기분무류의 응축열전달에 관하여 실험을 행하고 상당 Reynolds수를 근거로한 열전달효과와의 비교에서 그 결과를 요약하면 다음과 같다. 1. 관내 응축증기 분무류일 경우의 벽면전단응력의 식은 다음과 같이 쓸 수 있다. root($\tau$하(0)/$\tau$하(0v))=1+1.46X 하(tt) 상(0.20). 2. 분무류의 응축열전달효과가 상당 Reynolds수에 의한 값보다 대체로 낮게 나타난 이유는 관내 반경 및 길이방향의 불균일한 액막형성에 의한 Reynolds수 측정값의 차이 때문이다. 3. 분무류의 응축열전달효과에 의한 N sub(u)의 값은 다음과 같다. N 하(u)=1.08$\times$[{$\rho$ 하(l) d/$\mu$ 하(l)}/{$\delta$+(2.5/P 하(rl)) ln(y 하(i)/$\delta$)}]$\times${$\tau$ 하(0)/ $\rho$ 하(l)} 상(1/2)

• 한국재료학회지
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• 제23권3호
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• pp.194-198
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• 2013

In this paper, we studied a p-type reflector based on indium tin oxide (ITO) for vertical-type ultraviolet light-emitting diodes (UV LEDs). We investigated the reflectance properties with different deposition methods. An ITO layer with a thickness of 50 nm was deposited by two different methods, sputtering and e-beam evaporation. From the measurement of the optical reflection, we obtained 70% reflectance at a wavelength of 382 nm by means of sputtering, while only 30% reflectance resulted when using the e-beam evaporation method. Also, the light output power of a $1mm{\times}1mm$ vertical chip created with the sputtering method recorded a twofold increase over a chip created with e-beam evaporation method. From the measurement of the root mean square (RMS), we obtained a RMS value 1.3 nm for the ITO layer using the sputtering method, while this value was 5.6 nm for the ITO layer when using the e-beam evaporation method. These decreases in the reflectance and light output power when using the e-beam evaporation method are thought to stem from the rough surface morphology of the ITO layer, which leads to diffused reflection and the absorption of light. However, the turn-on voltage and operation voltage of the two samples showed identical results of 2.42 V and 3.5 V, respectively. Given these results, we conclude that the two ITO layers created by different deposition methods showed no differences in the electric properties of the ohmic contact and series resistance.

• Restorative Dentistry and Endodontics
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• 제22권2호
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• pp.680-692
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• 1997

New bonding agent systems have been supplied which operators can simply apply to conditioned tooth surfaces. The purpose of this study was to evaluate the shear bond strengths and the microleakages of three bonding agents and composite resins to dentin. Seventy-five extracted human maxillary and mandibular molar teeth were used in this study. For the shear bond strength test, the entire occlusal dentin surfaces of thirty teeth were exposed with Diamond Wheel Saw and smoothed with Lapping and Polishing Machine (South Bay Technology Co., U.S.A). For the microleakage test, Class V cavities were prepared in the buccal surfaces of fourtyfive teeth. They were randomly assigned into 3 groups according to dentin bonding agents ($Scotchbond^{TM}$ Multi-Purpose plus, ONE-$STEP^{TM}$ and Prime & $Bond^{TM}$)and composite resins (Z-100, $Aelitefil^{TM}$ and TPH $Spectrum^{TM}$) to be used. Bonding agents and composite resins were bonded to exposed dentin surfaces of the tooth crown and to Class V cavities on the buccal surfaces respectively according to manufacturer's directions. The shear bond strengths were measured by universal testing machine($U^{TM}$ AGS-100, Japan). In addition, the degree of micro leakage at the occlusal and gingival margin was examined by 2 % methylene blue and stereomicroscope(Olymous SZH 10, Japan). The results were as follows: 1. The shear bond strength to dentin was the highest value in SBMP-Plus group($16.68{\pm}7.38$ MPa) and the lowest value in Prime & Bond group($11.61{\pm}5.82$ MPa), but there was no significant difference of shear bond strength among three groups. 2. The degree of microleakage at both occlusal and gingival margin was showed the lowest in SBMP-Plus group and the highest in ONE-STEP group. 3. At both occlusal and gingival margin, there was significant difference of microleakage between SBMP-Plus and ONE-STEP/ Prime & Bond groups(p<0.05), but no significant difference of microleakage between ONE-STEP and Prime & Bond group(p>0.05).

• 한국식품과학회지
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• 제26권4호
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• pp.428-435
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• 1994

쌀전분의 다각적 이용을 위하여 고순도의 멥쌀전분과 찹쌀전분을 Alkali 침지법에 의해 제조하여 각각 드럼 건조기와 압출성형기로 변성전분을 제조한 후 특성을 검토하였다. 청값은 찹쌀전분이 가장 낮았으며 변성 후 L값이 감소하였다. 수분용해지수는 압출성형기로 제조한 변성전분들이 높은 값을 나타내었으며 수분흡수지수는 드럼건조기로 제조한 변성전분들이 높았다. Cold-Water-Solubility는 측정에서는 드럼건조기를 이용한 멥쌀변성전분이 가장 높았다. 각 시료들의 광투과도는 온도 증가에 따라 일정한 양상을 보이지 않았다. 드럼건조기로 제조한 멥쌀변성전분은 전단속도의 증가에 따라 점조성지수가 급격히 증가하였으며 항복응력도 가장 높은 값을 나타내었다. Gel Permeation Chromatography에 의하면 전분을 변성시킴에 따라 분자길이의 절단과 아밀로오스 분해가 일어남을 알 수 있었으며 X-선 간섭도형측정(XRI)에 의한 간섭도형은 피크를 상실한 V도형의 X-선 회절양상을 보임으로서 결정구조가 무정형으로 변화 된 것을 알 수 있었다.

• 약학회지
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• 제35권6호
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• pp.473-482
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• 1991

Protein methylase II (S-adenosyl-L-methionine:protein carboxyl-O-methyltransferase; EC 2.1.1.24., PM II) was purified from chicken pancreas by subcellular fractionation, DEAE-cellulose chromatography, QAE-Sephadex A-50 chromatography, Sephadex G-75 chromatography, and Sephadex G-75 rechromatography. The purified PM II gave a single band upon polyarcrylamide gel electrophoresis both in the presence of SDS and in Tris glycine buffer without SDS. The pI value of purified PM II was identified as 5.7 on isoelectric focusing gel. Properties and activities of PM II were studied and the following results were obtained. 1) PM II from chicken pancreas was purified approximately 221-fold with a yield of 1.3%. 2) The purified PM II appear constituted of a single polypeptide chain of a molecular weight 46,800 daltons. 3) Hemoglobin exhibited the highest of methyl-accepting activity among the substrates tested. 4) The purified PM II has a $K_m$ of $4.67{\times}10^{-6}M$ and a $V_{max}$ of 37.5 pmoles of $methyl-^{14}C/min./mg$ enzyme for $SAM^{-14}CH_3$ as methyl donor in the presence of histone type II-As. 5) It is found that S-adenosyl-L-homocysteine is a competitive inhibitor for PM II with $K_i$ value of $3.23{\times}10^{-5}M$.

• 전기학회논문지
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• 제67권10호
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• pp.1370-1374
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• 2018

A heterojunction $SnS_2/p-Si$ photodetector was fabricated by RF magnetron sputtering system. $SnS_2$ was formed with 2-inch $SnS_2$ target. Al was applied as the front and the back metal contacts. Rapid thermal process was conducted at $500^{\circ}C$ to enhance the contact quality. 2D material such as $SnS_2$, MoS2 is very attractive in various fields such as field effect transistors (FET), photovoltaic fields such as photovoltaic devices, optical sensors and gas sensors. 2D material can play a significant role in the development of high performance sensors, especially due to the advantages of large surface area, nanoscale thickness and easy surface treatment. Especially, $SnS_2$ has a indirect bandgap in the single and bulk states and its value is 2 eV-2.6 eV which is considerably larger than that of the other 2D material. The large bandgap of $SnS_2$ offers the advantage for the large on-off current ratio and low leakage current. The $SnS_2/p-Si$ photodetector clearly shows the current rectification when the thickness of $SnS_2$ is 80 nm compared to when it is 135 nm. The highest photocurrent is $19.73{\mu}A$ at the wavelength of 740 nm with $SnS_2$ thickness of 80 nm. The combination of 2D materials with Si may enhance the Si photoelectric device performance with controlling the thickness of 2D layer.

• 환경영향평가
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• 제8권3호
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• pp.49-59
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• 1999

In this study, we individualize the clauses to sort out the troubled ones, draw up a interrelation model in order to visually organize the relations, and finally, suggest the desirable application idea. The interrelation model suggested in this study has been made based on the matrix method. On this matrix, we arranged the environmental factors on horizontal and vertical axis, and when we describe the relation of each factors, we set the horizontal axis as the base and divided the content into three grades : Fine, Medium, and Poor. In addition to that, we expressed those three grades into numerical value like 3 points for Level Fine, 2 points for Level Medium, and 1 point for Level Poor and then, we converted this numerical values into index numbers. We could classify the index numbers such as AS, PS, Q-index, P-index. AS is an index numerically shows the degree of giving environmental effect, PS is an index numerically shows the degree of receiving environmental effect, Q-index is an index shows the aggravate degree, and P-index shows the relation degree. The Q/P-index with large numbers has considerable effect on the environmental system, while the small numbered Q/P-index barely effect on the environmental system. Moreover, we classified the environmental factors into 5 levels(I~V) according to the relations between the Q-index and P-index. Level I is less affected by the environment and has more giving effect, while Level V is more sensitively affected by the environment and has more receiving effect, which we considered important. Therefore, we could come up with the result that if we consider the each level of factors when we evaluate the EIA, the result would be far more accurate and reliable since it contains mutual relation aspect of EIA. The suggested interrelation model in this thesis is presentable as one of those scoping system. We highly believe the need of scoping system in EIA and suggest the interrelation model as the alternative idea for scoping system.

• KSBB Journal
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• 제13권6호
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• pp.693-699
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• 1998

고정화한 P. phosphoreum의 biolummescence악 독생물질과의 상관관계를 이용한 수계의 독성물질 momtonng 가능성을 조사하였다. P. phosphoreum을 이용한 수계의 독성물질 momtonng을 위한 적정 세포 농도는 최대 biolummescence intensnty를 보인 $O.D_{660}$ 1.0~1.2였으며 이 농도외 세포를 2.5% NaCl 용액에 희석하여 5.0%의 alginateo에 고정화 했을 때 biolummescence 유지도까 가장 좋았다. 이러한 방법으로 monitoring이 가능한 수계의 pH는 6.0~8.0이었다. Free cell과 고정화 세포로 $CdCl_2.H_20, PbCl_2, phenol $그리고 mtrophenol에 대한 bioluminescence를 조사하였을 때 고정화 방법에 의해 독성물질에 대한 민감성0] 증가되었다. 고정화 세포외 경우 각 독성 물질에 따라 20분 이내에 0.01~1.50ppm이하까지 mornitoring이 가능하였다. 뿐만 아니라 speciflC blolurninescence reclucLion rate, biolummescence mtenslLy의 ratio 그리고 Gamma value로 분석함으로서 독성물질의 농도와 biolummescence의 변화를 직선의 관계로 나타낼 수 있어 독성 물질의 농도 예측이 가능하다.