• Title/Summary/Keyword: P-V value

Search Result 1,083, Processing Time 0.034 seconds

Relationship between paravertebral muscle twitching and long-term effects of radiofrequency medial branch neurotomy

  • Koh, Jae Chul;Kim, Do Hyeong;Lee, Youn Woo;Choi, Jong Bum;Ha, Dong Hun;An, Ji Won
    • The Korean Journal of Pain
    • /
    • v.30 no.4
    • /
    • pp.296-303
    • /
    • 2017
  • Background: To achieve a prolonged therapeutic effect in patients with lumbar facet joint syndrome, radiofrequency medial branch neurotomy (RF-MB) is commonly performed. The purpose of this study was to evaluate the prognostic value of paravertebral muscle twitching when performing RF-MB in patients with lumbar facet joint syndrome. Methods: We collected and analyzed data from 68 patients with confirmed facet joint syndrome. Sensory stimulation was performed at 50 Hz with a 0.5 V cut-off value. Patients were divided into 3 groups according to the twitching of the paravertebral muscle during 2 Hz motor stimulation: 'Complete', when twitching was observed at all needles; 'Partial', when twitching was present at 1 or 2 needles; and 'None', when no twitching was observed. The relationship between the long-term effects of RF-MB and paravertebral muscle twitching was analyzed. Results: The mean effect duration of RF-MB was 4.6, 5.8, and 7.0 months in the None, Partial, and Complete groups, respectively (P = 0.47). Although the mean effect duration of RF-MB did not increase significantly in proportion to the paravertebral muscle twitching, the Complete group had prolonged effect duration (> 6 months) than the None group in subgroup analysis. (P = 0.03). Conclusions: Paravertebral muscle twitching while performing lumbar RF-MB may be a reliable predictor of long-term efficacy when sensory provocation under 0.5 V is achieved. However, further investigation may be necessary for clarifying its clinical significance.

Association of Two Polymorphisms of DNA Polymerase Beta in Exon-9 and Exon-11 with Ovarian Carcinoma in India

  • Khanra, Kalyani;Panda, Kakali;Bhattacharya, Chandan;Mitra, A.K.;Sarkar, Ranu;Bhattacharyya, Nandan
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.13 no.4
    • /
    • pp.1321-1324
    • /
    • 2012
  • Background: DNA polymerase beta ($pol{\beta}$) is a key enzyme in the base excision repair pathway. It is 39kDa protein, with two subunits, one large subunit of 31 kDa having catalytic activity between exon V to exon XIV, and an 8 kDa smaller subunit having single strand DNA binding activity. Exons V to VII have double strand DNA binding activity, whereas exons VIII to XI account for the nucleotidyl transferase activity and exons XII to XIV the dNTP selection activity. Aim: To examine the association between $pol{\beta}$ polymorphisms and the risk of ovarian cancer, the present case control study was performed using 152 cancer samples and non-metastatic normal samples from the same patients. In this study, mutational analysis of $pol{\beta}$ genomic DNA was undertaken using primers from exons IX to XIV - the portion having catalytic activity. Results: We detected alteration in DNA polymerase beta by SSCP. Two specific heterozygous point mutations of $pol{\beta}$ were identified in Exon 9:486, A->C (polymorphism 1; 11.18%) and in Exon 11:676, A->C (polymorphism 2; 9.86%). The correlation study involving polymorphism 1 and 4 types of tissue showed a significant correlation between mucinous type with a Pearson correlation value of 4.03 (p=0.04). The association among polymorphism 2 with serous type and stage IV together have shown Pearson ${\chi}^2$ value of 3.28 with likelihood ratio of 4.4 (p=0.07) with OR =2.08 (0.3-14.55). This indicates that there is a tendency of correlation among polymorphism 2, serous type and stage IV, indicating a risk factor for ovarian cancer. Conclusion: Hence, the results indicate that there is a tendency for $pol{\beta}$ polymorphisms being a risk factor for ovarian carcinogenesis in India.

Heat Transfer of Condensation by the Injecting Steam Flow In Tube (관내연기 분무류의 응축열전달)

  • 김시영
    • Journal of the Korean Society of Fisheries and Ocean Technology
    • /
    • v.20 no.2
    • /
    • pp.137-142
    • /
    • 1984
  • An experimental study has been performed on the heat transfer characteristics of condensation by the injecting steam flow in the tube. The comparison between results of experimental data and available data concerning equivalent Reynolds number has studied. As the result, the followings were obtained. 1. The shear stress of the radial direction in the tube when the injecting steam flow was condensed can be written as root($\tau$sub(0)/$\tau$sub(0v))=1+1.46X sub(tt) super(0.20). 2. The effect of the heat transfer in the injecting steam flow was less than the value of equivalent Reynolds number. The reason are the nonuniform fluid film of the axial and radial direction in the tube. 3. The value of N sub(u) by the heat transfer of condensation can be written as N sub(u)=1.08$\times$[{$\rho$ sub(l) d/$\mu$ sub(l)}/{$\delta$+(2.5/P sub(rl)) ln(y sub(i)/$\delta$)}]$\times${$\tau$ sub(0)/ $\rho$ sub(l)} super(1/2).

  • PDF

Indium Tin Oxide Based Reflector for Vertical UV LEDs (자외선 수직형 LED 제작을 위한 Indium Tin Oxide 기반 반사전극)

  • Jung, Ki-Chang;Lee, Inwoo;Jeong, Tak;Baek, Jong Hyeob;Ha, Jun-Seok
    • Korean Journal of Materials Research
    • /
    • v.23 no.3
    • /
    • pp.194-198
    • /
    • 2013
  • In this paper, we studied a p-type reflector based on indium tin oxide (ITO) for vertical-type ultraviolet light-emitting diodes (UV LEDs). We investigated the reflectance properties with different deposition methods. An ITO layer with a thickness of 50 nm was deposited by two different methods, sputtering and e-beam evaporation. From the measurement of the optical reflection, we obtained 70% reflectance at a wavelength of 382 nm by means of sputtering, while only 30% reflectance resulted when using the e-beam evaporation method. Also, the light output power of a $1mm{\times}1mm$ vertical chip created with the sputtering method recorded a twofold increase over a chip created with e-beam evaporation method. From the measurement of the root mean square (RMS), we obtained a RMS value 1.3 nm for the ITO layer using the sputtering method, while this value was 5.6 nm for the ITO layer when using the e-beam evaporation method. These decreases in the reflectance and light output power when using the e-beam evaporation method are thought to stem from the rough surface morphology of the ITO layer, which leads to diffused reflection and the absorption of light. However, the turn-on voltage and operation voltage of the two samples showed identical results of 2.42 V and 3.5 V, respectively. Given these results, we conclude that the two ITO layers created by different deposition methods showed no differences in the electric properties of the ohmic contact and series resistance.

A STUDY ON THE SHEAR BOND STRENGTHS AND MICROLEAKAGES OF THREE BONDING AGENTS ON DENTIN (상아질 접착제의 전단결합강도와 미세누출에 관한 연구)

  • Kim, Jeong-Ho;Cho, Young-Gon;Moon, Joo-Hoon
    • Restorative Dentistry and Endodontics
    • /
    • v.22 no.2
    • /
    • pp.680-692
    • /
    • 1997
  • New bonding agent systems have been supplied which operators can simply apply to conditioned tooth surfaces. The purpose of this study was to evaluate the shear bond strengths and the microleakages of three bonding agents and composite resins to dentin. Seventy-five extracted human maxillary and mandibular molar teeth were used in this study. For the shear bond strength test, the entire occlusal dentin surfaces of thirty teeth were exposed with Diamond Wheel Saw and smoothed with Lapping and Polishing Machine (South Bay Technology Co., U.S.A). For the microleakage test, Class V cavities were prepared in the buccal surfaces of fourtyfive teeth. They were randomly assigned into 3 groups according to dentin bonding agents ($Scotchbond^{TM}$ Multi-Purpose plus, ONE-$STEP^{TM}$ and Prime & $Bond^{TM}$)and composite resins (Z-100, $Aelitefil^{TM}$ and TPH $Spectrum^{TM}$) to be used. Bonding agents and composite resins were bonded to exposed dentin surfaces of the tooth crown and to Class V cavities on the buccal surfaces respectively according to manufacturer's directions. The shear bond strengths were measured by universal testing machine($U^{TM}$ AGS-100, Japan). In addition, the degree of micro leakage at the occlusal and gingival margin was examined by 2 % methylene blue and stereomicroscope(Olymous SZH 10, Japan). The results were as follows: 1. The shear bond strength to dentin was the highest value in SBMP-Plus group($16.68{\pm}7.38$ MPa) and the lowest value in Prime & Bond group($11.61{\pm}5.82$ MPa), but there was no significant difference of shear bond strength among three groups. 2. The degree of microleakage at both occlusal and gingival margin was showed the lowest in SBMP-Plus group and the highest in ONE-STEP group. 3. At both occlusal and gingival margin, there was significant difference of microleakage between SBMP-Plus and ONE-STEP/ Prime & Bond groups(p<0.05), but no significant difference of microleakage between ONE-STEP and Prime & Bond group(p>0.05).

  • PDF

Properties of Modified Rice Starch by Physical Modification (물리적 변성에 의한 쌀변성전분의 이화학적 성질)

  • Kum, Jun-Seok;Lee, Hyun-Yu;Shin, Myoung-Gon;Yoo, Mi-Ra;Kim, Kil-Hwan
    • Korean Journal of Food Science and Technology
    • /
    • v.26 no.4
    • /
    • pp.428-435
    • /
    • 1994
  • Properties of modified rice starches prepared in drum drying and extrusion were evaluated to use for effective utilization. Blue value was the lowest (p<0.05) for waxy rice starch and L value was decreased after modification of starches. Water solubility index was the highest for modified starches prepared in extrusion, while water absorption index was the highest for modified starches prepared in drum drying. Cold-Water-Solubility was the highest (p<0.05) for modified rice starch prepared in drum drying (RD). Consistency index of RD was drastically increased as shear rate increased and yield stress was the highest for RD. Results of Gel Permeation Chromatography showed that starch components were broken down into lower molecular weight materials and amylose are degraded by modification. Changes in the X-ray diffrectometry pattern indicated the transformation of granule into an amorphous state during modification and illustrated V-type.

  • PDF

Protein Methylase II from Chicken Pancreas: Purification and Properties (닭 췌장 Protein Methylase II의 분리정제 및 성질)

  • Yoo, Tae-Moo;Namkoong, Suck-Min;Hong, Sung-Youl;Lee, Hyang-Woo
    • YAKHAK HOEJI
    • /
    • v.35 no.6
    • /
    • pp.473-482
    • /
    • 1991
  • Protein methylase II (S-adenosyl-L-methionine:protein carboxyl-O-methyltransferase; EC 2.1.1.24., PM II) was purified from chicken pancreas by subcellular fractionation, DEAE-cellulose chromatography, QAE-Sephadex A-50 chromatography, Sephadex G-75 chromatography, and Sephadex G-75 rechromatography. The purified PM II gave a single band upon polyarcrylamide gel electrophoresis both in the presence of SDS and in Tris glycine buffer without SDS. The pI value of purified PM II was identified as 5.7 on isoelectric focusing gel. Properties and activities of PM II were studied and the following results were obtained. 1) PM II from chicken pancreas was purified approximately 221-fold with a yield of 1.3%. 2) The purified PM II appear constituted of a single polypeptide chain of a molecular weight 46,800 daltons. 3) Hemoglobin exhibited the highest of methyl-accepting activity among the substrates tested. 4) The purified PM II has a $K_m$ of $4.67{\times}10^{-6}M$ and a $V_{max}$ of 37.5 pmoles of $methyl-^{14}C/min./mg$ enzyme for $SAM^{-14}CH_3$ as methyl donor in the presence of histone type II-As. 5) It is found that S-adenosyl-L-homocysteine is a competitive inhibitor for PM II with $K_i$ value of $3.23{\times}10^{-5}M$.

  • PDF

SnS2/p-Si Heterojunction Photodetector (SnS2/p-Si 이종접합 광 검출기)

  • Oh, Chang-Gyun;Cha, Yun-Mi;Lee, Gyeong-Nam;Jung, Bok-Mahn;Kim, Joondong
    • The Transactions of The Korean Institute of Electrical Engineers
    • /
    • v.67 no.10
    • /
    • pp.1370-1374
    • /
    • 2018
  • A heterojunction $SnS_2/p-Si$ photodetector was fabricated by RF magnetron sputtering system. $SnS_2$ was formed with 2-inch $SnS_2$ target. Al was applied as the front and the back metal contacts. Rapid thermal process was conducted at $500^{\circ}C$ to enhance the contact quality. 2D material such as $SnS_2$, MoS2 is very attractive in various fields such as field effect transistors (FET), photovoltaic fields such as photovoltaic devices, optical sensors and gas sensors. 2D material can play a significant role in the development of high performance sensors, especially due to the advantages of large surface area, nanoscale thickness and easy surface treatment. Especially, $SnS_2$ has a indirect bandgap in the single and bulk states and its value is 2 eV-2.6 eV which is considerably larger than that of the other 2D material. The large bandgap of $SnS_2$ offers the advantage for the large on-off current ratio and low leakage current. The $SnS_2/p-Si$ photodetector clearly shows the current rectification when the thickness of $SnS_2$ is 80 nm compared to when it is 135 nm. The highest photocurrent is $19.73{\mu}A$ at the wavelength of 740 nm with $SnS_2$ thickness of 80 nm. The combination of 2D materials with Si may enhance the Si photoelectric device performance with controlling the thickness of 2D layer.

Study on the Interrelationship among the Environmental Factors in Environmental Impact Assessment (환경영향평가에서의 평가항목간 상호연계성에 관한 연구)

  • Kang, Myung-Hwi;Lee, Mu-Choon
    • Journal of Environmental Impact Assessment
    • /
    • v.8 no.3
    • /
    • pp.49-59
    • /
    • 1999
  • In this study, we individualize the clauses to sort out the troubled ones, draw up a interrelation model in order to visually organize the relations, and finally, suggest the desirable application idea. The interrelation model suggested in this study has been made based on the matrix method. On this matrix, we arranged the environmental factors on horizontal and vertical axis, and when we describe the relation of each factors, we set the horizontal axis as the base and divided the content into three grades : Fine, Medium, and Poor. In addition to that, we expressed those three grades into numerical value like 3 points for Level Fine, 2 points for Level Medium, and 1 point for Level Poor and then, we converted this numerical values into index numbers. We could classify the index numbers such as AS, PS, Q-index, P-index. AS is an index numerically shows the degree of giving environmental effect, PS is an index numerically shows the degree of receiving environmental effect, Q-index is an index shows the aggravate degree, and P-index shows the relation degree. The Q/P-index with large numbers has considerable effect on the environmental system, while the small numbered Q/P-index barely effect on the environmental system. Moreover, we classified the environmental factors into 5 levels(I~V) according to the relations between the Q-index and P-index. Level I is less affected by the environment and has more giving effect, while Level V is more sensitively affected by the environment and has more receiving effect, which we considered important. Therefore, we could come up with the result that if we consider the each level of factors when we evaluate the EIA, the result would be far more accurate and reliable since it contains mutual relation aspect of EIA. The suggested interrelation model in this thesis is presentable as one of those scoping system. We highly believe the need of scoping system in EIA and suggest the interrelation model as the alternative idea for scoping system.

  • PDF

The Character of Bioluminescence of Photobacterium phosphoreum with Toxic Substances (동석물질에 대한 Photobacterium phosphoreum의 bioluminescence 특성)

  • 이홍주;이은수;박철진;이정건;전억한
    • KSBB Journal
    • /
    • v.13 no.6
    • /
    • pp.693-699
    • /
    • 1998
  • The relationship between bioluminescence of immobilized Photobacterium phosphoreum and toxic substances was investigated to monitor toxic substances in aqueous solution. The sodium alginate was used as an immobilization matrix. A bioluminescence intensity was maximum when OD660 for cell concentration were between 1.0 and 1.2 and the biolumescence was stable at the pH range of between 6.0 and 8.0. The optimum concentration of alginate for immobilization was found to be 5.0%(w/v) in which dilution was carried out with 2.5%(w/v) NaCl solution that is an optimum environmental condition for the growth of P. phosphoreum. The bioluminescence intensity responded against the toxic substances was proportional to the concentration and a regression curve were established with linearity by using specific bioluminescence reduction rate and Gamma values. It was also found that the response was very rapid and sensitive. The response with such rapidity and sensitivity is a very important factor for the real time monitoring. The immobilized cells showed higher sensitive response to the toxic substances than free cells.

  • PDF