• Title/Summary/Keyword: P-Turn

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Enhanced Productivity By Development Of Isometric Pre-Erection (입체 PE 개발을 통한 생산성 향상)

  • Lee Jongseob;Kim Younghwan;Joe Jongrae
    • Special Issue of the Society of Naval Architects of Korea
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    • 2005.06a
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    • pp.185-191
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    • 2005
  • Korean naval architecture company today is making researches in expansion of productivity of their own accord. In result, they have accomplished many technical developments like a ground shipbuilding system. For our company's productivity expansion in our yard's limited condition (the facility, P.E area, stock area), we develop isometric pre-erection method that turn into a possibility to maximize our facility use, minimize our dock period.

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Structure-Activity Relationships of Peptide Antibiotics with Improved Bacterial Cell Selectivity of Pseudin

  • Lee, Yeongjoon;Jeon, Dasom;Kim, Jin-Kyoung;Kim, Yangmee
    • Journal of the Korean Magnetic Resonance Society
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    • v.21 no.3
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    • pp.78-84
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    • 2017
  • Pseudin is a naturally occurring 24 amino-acid-residue antimicrobial peptide derived from the skin of paradoxical frog Pseud's paradoxa. It shows potency against the bacteria and antibiotic-resistant bacteria strain, but has high cytotoxicity against mammalian cell. In our previous study, substitution of $Pro^{11}$ for Gly (Ps-P) increased bacterial cell selectivity but decreased the antibacterial activity of pseudin. In this study, we designed pseudin analogue, Ps-4K-P with increased cationicity up to +7 in Ps-P by substituting Glu14, Gln10, Gln24, and Leu18 with Lys. Ps-4K-P showed improved potent antibacterial activity with high bacterial cell selectivity. We determined the tertiary structure of Ps-4K-P in the presence of DPC micelles by NMR spectroscopy and it has a hinge structure at $Pro^{11}$ followed by three turn helices from $Pro^{11}$ to $Val^{23}$ at the C-terminus. Amphipathicity with increased cationicity as well as helix-hinge-helix structural motif provided by introduction of a Pro at position $Gly^{11}$ are the crucial factors which confer antibacterial activity with bacterial cell selectivity to Ps-4K-P.

Physicochemical Properties of Chaga (Inonotus obliquus) Mushroom Powder as Influenced by Drying Methods

  • Lee, Min-Ji;Seog, Eun-Ju;Lee, Jun-Ho
    • Preventive Nutrition and Food Science
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    • v.12 no.1
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    • pp.40-45
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    • 2007
  • The effects of drying methods on the physicochemical properties of chaga (Inonotus obliquus) mushroom powder were investigated. Scanning electron micrograph revealed that freeze drying produced smaller particle- sized samples which in turn resulted in higher porosity than did vacuum and hot-air drying. Samples prepared by freeze drying showed a significantly higher L*-value as compared with those prepared by hot-air drying and vacuum drying (p<0.05). The lightness (L*-value) significantly decreased with increasing relative humidity and storage temperature regardless of drying method (p<0.05). The yellowness (b*-value) increased significantly with increasing relative humidity (p<0.05). Browning index was significantly lower in samples prepared by freeze drying (p<0.05) but not significantly different between samples dried by hot-air and vacuum drying. Freeze dried sample exhibited a significantly higher degree of rehydration than other samples (p<0.05) probably due to the small particle size. Water solubility of the freeze dried sample was higher than those of the other methods while swelling ratio of the same sample appeared to be lower than those of others. Freeze dried chaga mushroom powder contained significantly lower amount of total phenolics and total sugar as compared to other samples (p<0.05).

Effect of Cultural Conditions on the Lipid Production by Moulds (곰팡이 유지 생산에 관한 배양조건의 영향)

  • 손병효;정태명;김용균;최상욱
    • Korean Journal of Microbiology
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    • v.23 no.4
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    • pp.252-258
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    • 1985
  • Aspergillus niger var. macrospours, Aspergillus fumigatus, Penicillium notatum and Penicillium spinulosum were cultured under different cultural conditions. The lipids produced by these species and fatty acid compositions of lipids were investigated. The macimum lipid contents produced by each species were 17.8% for Asp. niger var. macrosporus, 31% for Asp. fumigatus, 12.6% for P. notatum and 17.5% for P. spinulosum, respectively. The major fatty acid compositions were palmitic acid, stearic acid, oleic acid and linoleic acid. Asp. niger var. macrosporus and Asp. fumigatus were highest oleic acid during all incubation periods and P. notatum and P. spinulsum were linoleic acid. Degree of unsaturation was higher Penicillium than Aspergillus. The fatty acid compositions were changed depending on the incubation temperature, but hardly showed a certain tendency except linoleic acid and degree of unsaturation that were higher at lower temperature.

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A High Efficiency DC-DC Converter Using IGBT-MOSFET Parallel Switches (IGBT-MOSFET 병렬 스위치를 이용한 고효율 직류-직류 변환기)

  • 장동렬;서영민;홍순찬;윤덕용;황용하
    • The Transactions of the Korean Institute of Power Electronics
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    • v.4 no.2
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    • pp.152-158
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    • 1999
  • Due to high power ratings and low conduction loss, the TGBT has become more attractive in switching power supplies. However, its lower turn-on and turn-off characteristics than those of MOSFET cause severe switching loss and s switching frequency limitation. This paper proposes 2.4kW. 48V. high efficiency half-bridge DC-DC converter using p paralleled TGBT-MOSFET switch concept to use the merits of TGBTs and MOSFETs. Tn parallel switches. each of I TGBT and MOSFET plays its part during on-periods and switching instants. The switching loss is analyzed by l linearized modelling and the operation of the converter are investigated by simulation results.

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The Topology of Soft Switching Boost Type DC-DC Converter using a Passive Auxiliary Resonant Snubber (패시브 보조 공진 스너버를 이용한 소프트 스위칭 승압형 DC-DC 컨버터의 토폴로지)

  • Sung, Chi-Ho;Park, Han-Seok
    • The Transactions of the Korean Institute of Electrical Engineers P
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    • v.64 no.3
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    • pp.146-152
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    • 2015
  • In this paper, we propose a boost DC-DC converter using a modification of the passive auxiliary resonant snubber circuit with a DC-DC converter in a typical active auxiliary resonant snubber-bridge inverter. The proposed boost DC-DC converter is small compared to the DC-DC converter according to the soft-switching scheme that requires a general auxiliary switch by realizing the soft switching operation as a DC-DC converter which does not require an auxiliary switch. It is light-weight, switch the turn-on and turn-off switching loss at the time of the superposition of the voltage and current is extremely small, so small. And the reduction of the surge voltage and current of the switch. In addition, the proposed boost DC-DC converter has a high efficiency over a wide load characteristics change area than conventional hard switching PWM boost converter using an RC snubber loss.

The Study on Characteristics of Green Organic Light Emitting Device with Transparency Conductive Oxide Electrodes (투명전도성 산화물 전극에 따른 Green OLED의 특성연구)

  • Ki, Hyun-Chul;Kim, Seon-Hoon;Kim, Hwe-Jong;Kim, Sang-Gi;Choi, Young-Sung;Hong, Kyung-Jin
    • The Transactions of the Korean Institute of Electrical Engineers P
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    • v.58 no.4
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    • pp.615-618
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    • 2009
  • In order to apply for transparent conductive oxide(TCO), we deposited ZnO thin film on the glass at room temperature by RF magnetron sputtering method. Deposition conditions for low resistivity were optimized in our previous studies. Under the deposition condition with the RF power of 800 [W]. Sheet resistance and surface roughness of ITO and ZnO thin film were measured by Hall-effect measurement system and AFM, respectively. The sheet resistance of ITO and ZnO thin film were 7.290 [$\Omega$] and 4.882 [$\Omega$], respectively. and surface roughness were 3.634 [nm] and 0.491 [nm], respectively. Green OLED was fabricated with the structure of TPD(400 [$\AA$])/Alq3(600 [$\AA$])/LiF(5 [$\AA$])/Al(1200 [$\AA$]). Turn-on voltage of green OLED applied ITO was 7 [V] and luminance was 7,371 [$cd/m^2$]. And, Turn-on voltage of green OLED applied ZnO was 14 [V] and luminance was 6,332 [$cd/m^2$].

MEMS-BASED MICRO FLUXGATE SENSOR USING SOLENOID EXCITATION AND PICK-UP COILS (MEMS 공정 제작방법에 의한 솔레노이드형 여자 코일과 검출코일을 사용한 마이크로 플럭스게이트 센서)

  • 나경원;박해석;심동식;최원열;황준식;최상인
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2002.07a
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    • pp.172-176
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    • 2002
  • This paper describes a MEMS-based micro-fluxgate magnetic sensing element using Ni$\_$0.8/Fe$\_$0.2/ film formed by electroplating. The micro-fluxgate magnetic sensor composed of a thin film magnetic core and micro-structured solenoids for the pick-up and the excitation coils, is developed by using MEMS technologies in order to take advantage of low-cost, small size and lower power consumption in the fabrication. A copper with 20um width and 3um thickness is electroplated on Cr(300${\AA}$)/Au(1500${\AA}$) films for the pick-up(42turn) and the excitation(24turn) coils. In order to improve the sensitivity of the sensing element, we designed the magnetic core into a rectangular-ring shape to reduce the magnetic flux leakage. An electroplated permalloy film with the thickness of 3 $\mu\textrm{m}$ is obtained under 2000Gauss to induce magnetic anisotropy. The magnetic core has the high DC effective permeability of ∼1,100 and coercive field of -0.1Oe. The fabricated sensing element using rectangular-ring shaped magnetic film has the sensitivity of about 150V/T at the excitation frequency of 2MHz and the excitation voltage of 4.4Vp-p. The power consumption is estimated to be 50mW.

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Characteristics analysis of single-phase high power factor PWM boost rectifier (단상 고역률 PWM 승압형 정류기의 특성해석)

  • Kim, J.Y.;Mun, S.P.;Suh, K.Y.;Kim, Y.M.;Kim, H.J.
    • Proceedings of the KIEE Conference
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    • 2006.07b
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    • pp.1209-1210
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    • 2006
  • This paper presents a single phase high power factor PWM boost rectifier featuring soft commutat -ion of the active switches at zero current. It incorporates the most desirable properties of conventional PWM and soft switching resonant techniques. The input current shaping is achieved with average current mode control and continuous inductor current mode. This new PWM converter provides zero current turn on and turn off of the active switches, and it is suitable for high power applications employing IGBT's. The principle of operation, the theoretical analysis, a design example, and experi -mental results from a laboratory prototype rated at 1.6[kW] with 400[Vdc] output voltage are presented. The measured efficiency and the power factor were 96.2[%] and 0.99[%], respectively, with an input current THD equal to 3.94[%], for an input voltage with THD equal to 3.8[%], at rated load.

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Synthesis of New 2-Thiouracil-5-Sulphonamide Derivatives with Antibacterial and Antifungal Activity

  • Fathalla O. A.;Awad S. M.;Mohamed M. S.
    • Archives of Pharmacal Research
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    • v.28 no.11
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    • pp.1205-1212
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    • 2005
  • 2-Thiouracil-5-sulphonic acid N-(4-acetylphenyl) Amide (1) was reacted with a series of aromatic aldehydes giving chalcones 2 (Claisen-Schemidt reaction), some of these chalcones were reacted with urea and thiourea giving pyrimidine-2-one and pyrimidine-2 thione derivatives respectively of the type 3a,b and 4a,b. In addition many chalcones were reacted with hydroxylamine hydrochloride giving isoxazoline derivatives 5a,b. They could also reacted with phenylhydrazine to give pyrazoline derivatives 5a,b, chalcones also were reacted withethylcyano acetate and/or malononitryl in pyridine giving pyran derivatives 7a,c and 8a,c. In another pathway chalcones were epoxidised by $H_{2}O_{2}$ giving epoxides 9a,c which in turn were reacted with phenylhydrazine giving 4-hydroxypyrazoline derivatives 10a,c. In another reaction chalcones were reacted with ethylcyanoacetate in presence of amm.acetate giving pyridone derivatives 11a,d which could be prepared also in exellent yield from compound 1 by its reaction with certain aromatic aldehydes and ethylcyanoacetate in presence of ammonium acetate. Finally, compound 1 was reacted with semicarbazide giving semicarbazone intermediate 12 which in turn was reacted with thionyl chloride giving thiadiazole derivative 13. The biological effects of some of the new synthesized compounds were also investigated.