• Asian-Australasian Journal of Animal Sciences
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• v.22 no.1
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• pp.42-48
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• 2009

An in vitro incubation study was conducted to investigate effects of 2-bromoethanesulfonic acid (BES) on ruminal fermentation characteristics and methanogen population. BES at the final concentration of 0, 1 and 5 mM with two different substrates having a different ratio of timothy and concentrate (100% timothy vs. 40% timothy-60% concentrate) was incubated for 0, 24, 48 and 72 h in a $39^{\circ}C$ incubator. Total DNA extracted from culture fluid was used as a template for real-time PCR to measure the population of methanogens. Four different primer sets were used for amplification of total bacteria, total methanogens, the order Methanobacteriales and the order Methanomicrobiales. BES reduced (p<0.01) total gas and methane production in a dose-dependent manner. BES at 5 mM inhibited methane production by more than 95% compared to the control. An interaction between substrate and level of BES in total gas and methane was detected (p<0.01). The decrease of methane production with increasing BES level was more pronounced on mixed substrate than on timothy alone. However, hydrogen production was increased by BES treatment (p<0.01). Total VFA concentration was not affected, but molar percentage of propionate and butyrate was increased and acetate to propionate ratio was reduced by BES treatment (p<0.01). BES did not affect the population density of total bacteria but reduced (p<0.01) the population of total methanogens, the order Methanobacteriales and the order Methanomicrobiales in a dose-dependent manner. The type of substrate did not influence the trend, although the magnitude of response was different between all-roughage and 40% roughage substrate.

• Structural Engineering and Mechanics
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• v.31 no.6
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• pp.737-749
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• 2009

The problem of estimating the dynamic response of a distributed parameter system excited by a moving vehicle with random initial velocity and random vehicle body mass is investigated. By adopting the Galerkin's method and modal analysis, a set of approximate governing equations of motion possessing time-dependent uncertain coefficients and forcing function is obtained, and then the dynamic response of the coupled system can be calculated in deterministic sense. The statistical characteristics of the responses of the system are computed by using improved perturbation approach with respect to mean value. This method is simple and useful to gather the stochastic structural response due to the vehicle-passenger-bridge interaction. Furthermore, some of the statistical numerical results calculated from the perturbation technique are checked by Monte Carlo simulation.

• International Journal of Industrial Entomology and Biomaterials
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• v.11 no.2
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• pp.119-124
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• 2005

To determine the level of heterosis, higher cocoon shell weight multivoltine congenic lines (Con. L) and bivoltine syngenic lines (Syn. L) of silkworm were used for crosses. First filial generations $(F_1s)$ expressed heterobeltiotic genetic interaction at significant magnitude (p < 0.01) for single cocoon shell weight (SCSW). The other linked characters viz., single cocoon weight (SCW) and yield by weight per 10, 000 larvae were also significantly higher (p < 0.01) than the better parental lines. All the hybrids showed significant improvement for these aforesaid characters over standard heterosis (Standard check). The reeling parameters viz., filament length, raw silk, neatness, cohesionstrokes etc, also showed improvement among the hybrids than check in congenial environment. Overall results suggested that the cross between congenic and syngenic lines provide better heterosis with good quality silk than conventional hybrids and may be used for commercial exploitation.

• The Journal of Korean Physical Therapy
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• v.20 no.2
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• pp.19-24
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• 2008

Purpose: The purpose of this study was to examine how norepinephrine affects immunity in patients over age 65. Methods: We enrolled 25 male and female subjects age 65 or older. A low frequency electroacupuncture (EA) device was used to stimulate acupoint Hogu (L14). The 2 Hz frequency EA was applied to the acupoint for 20 minutes. Leukocyte subtypes-including neutrophils, lymphocytes, monocytes, eosinophils, and basophil-were then measured. The immunoglobulins IgG and IgM were also quantified. The data were finally analyzed using Wilcoxon singed-rank test and regression test as part of the SPSS WIN v. 10.1 program. Results: As norepinephrine levels decreased after EA stimulation, neutrophil, lymphocyte, and monocyte levels increased, and eosinophil and neutrophils levels decreased. Neutrophil and monocyte levels did not change to a statistically significant degree, but eosinophil levels showed a statistically significant decrease (p<0.05). Immunoglobulin IgG showed a statistically significant increase (p<0.05). Conclusion: This study showed that norepinephrine does affect immunity in persons over the age of 65. This indicates that there is an interaction between the nervous system and the immune system, and interaction that plays a crucial roles in the body's immune resistance and homeostasis.

• YAKHAK HOEJI
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• v.39 no.2
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• pp.175-184
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• 1995

The interaction of omeprazole(OMP) with $\gamma$-cyclodextrin($\gamma$-CyD) was investigated by solubility study and the complexation was confirmed by means of UV/VIS spectrophotometer, circular dichroism, differential scanning calorimeter, and $^{1}$H nuclear magnetic resonance spectra. The stability, dissolution rate, and partition coefficient of the complex were measured. The results present that the benzimidazole moiety and a part of pyridine ring containing sulfur atom of OMP might be included into the cavity of $\gamma$-CyD and the formation type of inclusion complex appeared to be B$_{s}$. The stoichiometric ratio of OMP to $\gamma$-CyD in the complex was found to be 1:1 and the stability constant of the complex found to be 97.1 M$^{-1}$. And the dissolution rate of OMP was markedly increased by inclusion complex formation with $\gamma$-CyD, and so it was above 90% in 5 min. from solid complex. Oil to water partition coefficient of OMP-$\gamma$-CyD complex was 60, which is significantly higher than that of OMP itself, 36.4. The degradation rate constant of OMP were greater than OMP-$\gamma$-CyD complex in aqueous solutions of various pHs, and the half lives of OMP and OMP-$\gamma$-CyD at pH 9 were 279.2 and 509.9 days, respectively, showing that the complex was more stable than OMP, therefore it was thought that OMP was stabilized by inclusion formation with $\gamma$-CyD.

• Korean Membrane Journal
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• v.3 no.1
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• pp.39-50
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• 2001

The counter-diffusion of two gaseous substances permeating a polymeric membrane has been investigated both experimentally and theoretically. The aim of the study was to find mutual effects, if any, that could influence the permeability and diffusivity data. The experimental data were obtained with an isostatic permeameter operating at ambient pressure and 303 K: helium, nitrogen, carbon dioxide methane were used as permeating gas at different partial pressure; helium or nitrogen as equilibrating or carrier gas. No evident mutual effect of the counter-diffusing gas was observed. The theoretical analysis gave some insight into the phenomena and it was concluded that at near-atmospheric pressures, and in the absence of swelling phenomena no mutual interaction exists. On a theoretical basis any mutual interaction between diffusing and counter-diffusing gases could only occur: i) at high pressures , when the free movement of permeating gas molecules within the polymer is hindered by the counter-diffusing gas; ii) when a large part of the free volume fraction is occupied by the counter--diffusing gas; iii) swelling phenomena modify the structure and free volume fraction of the polymer.

• Proceedings of the Korean Society of Soil and Groundwater Environment Conference
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• 2000.11a
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• pp.163-166
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• 2000

The purpose of this study is to evaluate substrate interactions of BTEX for multicomponent. Although BTEX compounds have similar chemical structures, biodegradation of individual BTEX is different with the present of certain BTEX compounds. The biodegradation rate is order to Benzene=Toluene>Ethylbenzene> m, p-Xylene>o-Xylene. Xylenes is stimulated when benzene or toluene is present. Especially o-xylene Inhibit other BTEX compounds.

• Wind and Structures
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• v.13 no.2
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• pp.169-189
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• 2010

This paper describes the use of coupled Computational Fluid Dynamics (CFD) and Rigid Body Dynamics (RBD) in modelling the aerodynamic behaviour of wind-borne plate type objects. Unsteady 2D and 3D Reynolds Averaged Navier-Stokes (RANS) CFD models are used to simulate the unsteady and non-uniform flow field surrounding static, forced rotating, auto-rotating and free-flying plates. The auto-rotation phenomenon itself is strongly influenced by vortex shedding, and the realisable k-epsilon turbulence modelling approach is used, with a second order implicit time advancement scheme and equal or higher order advection schemes for the flow variables. Sequentially coupling the CFD code with a RBD solver allows a more detailed modelling of the Fluid-Structure Interaction (FSI) behaviour of the plate and how this influences plate motion. The results are compared against wind tunnel experiments on auto-rotating plates and an existing 3D analytical model.

• Wind and Structures
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• v.17 no.3
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• pp.263-274
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• 2013

A numerical technique for fluid-structure interaction, which is based on the finite element method (FEM) and computational fluid dynamics (CFD), was developed for application to an industrial chimney equipped with a pendulum tuned mass damper (TMD). In order to solve the structural problem, a one-dimensional beam model (Navier-Bernoulli) was considered and, for the dynamical problem, the standard second-order Newmark method was used. Navier-Stokes equations for incompressible flow are solved in several horizontal planes to determine the pressure in the boundary of the corresponding cross-section of the chimney. Forces per unit length were obtained by integrating the pressure and are introduced in the structure using standard FEM interpolation techniques. For the fluid problem, a fractional step scheme based on a second order pressure splitting has been used. In each fluid plane, the displacements have been taken into account considering an Arbitrary Lagrangian Eulerian approach. The stabilization of convection and diffusion terms is achieved by means of quasi-static orthogonal subscales. For each period of time, the fluid problem was solved and the geometry of the mesh of each fluid plane is updated according to the structure displacements. Using this technique, along-wind and across-wind effects have been properly explained. The method was applied to an industrial chimney in three scenarios (with or without TMD and for different damping values) and for two wind speeds, showing different responses.

• Journal of the Korean Chemical Society
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• v.59 no.2
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• pp.117-124
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• 2015

The DFT and ab initio calculations have been performed to elucidate hydrogen interaction of hydrogen polyoxide dimers, $H_2O_n-H_2O_m$ (n=1-4, m=1-4). The optimized geometries, harmonic vibrational frequencies, and binding energies are predicted at various levels of theory. The harmonic vibrational frequencies of the molecules considered in this study show all real numbers implying true minima. The higher-order correlation effect were discussed to compare MP2 result with CCSD(T) single point energy. The binding energies were corrected for the zero-point vibrational energy (ZPVE) and basis set superposition errors (BSSE). The largest binding energy predicted at the CCSD(T)/cc-pVTZ level of theory is 8.18 kcal/mol for $H_2O_4-H_2O_3$ and the binding energy of water dimer is predicted to be 3.00 kcal/mol.