Purpose : The objectives of this study were to assess ventricular function by tissue Doppler imaging in children who were receiving chemotherapy or who had received chemotherapy, and to apply repeated tissue Doppler imaging to make an early assessment in cardiac toxicity studies. Methods : This study was conducted on 23 oncology patients on-treatment or off-treatment from April 2005 to July 2005 at Dongsan Medical Center, Keimyung University. All patients(group 1) were divided into two groups, fractional shortening(FS) over 29 percent(group 2) and FS under 28 percent (group 3) in the first category. These same patients were also divided into the following groups : group treated with anthracyclin(group 4) and group treated without anthracyclin(group 5). Deceleration time(DT), isovolumic relaxation time(IVRT), FS, peak early diastolic(E), and peak late diastolic (A) velocity of transmitral flow were measured by M-mode and pulsed wave Doppler. Systolic(Sm), peak early diastolic(Em), and peak late diastolic(Am) velocity in apical 4-chamber and 2-chamber views were measured by tissue Doppler imaging. The author calculated a modified Tei index, E/A, E/Em ratio by using measured values. Results : Twenty three patients were enrolled : 12 boys and 11 girls. The average age of patients was 8 years and 4 months. Thirteen out of 23 patients were in the group treated with anthracyclin (group 4) and 6 had FS under 28 percent(group 3). E/Em ratio showed a significant difference between group 1 and control group($6.46{\pm}1.85$ vs $7.06{\pm}1.64$, P<0.05). Other parameters had no difference statistically. Conclusion : This study showed that the change of cardiac function developed earlier in diastolic function than in systolic function, as E/Em ratio reflecting the mean LV diastolic pressure showed a significant difference between the control group and chemotherapy groups. Echocardiography using tissue Doppler imaging is a non-invasive, comfortable and reliable method for post-chemotherapy follow up.
Kim, Seog-Joo;Park, Doo-Heum;Kim, Yong-Sik;Woo, Jong-Inn;Ha, Kyoo-Seob;Jeong, Do-Un
Sleep Medicine and Psychophysiology
/
v.8
no.2
/
pp.113-120
/
2001
Objectives: Obstructive sleep apnea syndrome is common and may produce various symptoms and serious complications. A substantial number of research articles on obstructive sleep apnea syndrome have been published in Korea. However, we found such limitations as lack of sufficient sample size and lack of polysomnography-proven cases. Therefore, we aimed at studying clinical features and sleep structure in a sufficient number of Korean patients with obstructive sleep apnea syndrome diagnostically confirmed with polysomnography. Methods: We studied 801 subjects referred to the Division of Sleep Studies, Seoul National University Hospital, who were diagnosed as having obstructive sleep apnea syndrome with polysomnography. Subjects were excluded if they had central sleep apnea syndrome, periodic limb movement disorder, narcolepsy or REM sleep behavior disorder. Foreign patients were also excluded. First of all, we studied the clinical features of the subjects. Secondly, we compared sleep-related parameters of the study subjects with those of age/sex-matched normal values. Thirdly, correlations of respiratory disturbance index (RDI) with each of the sleep-related parameters were calculated. Results: Among the 801 subjects, 668 were male subjects (83.4%) and 133 female subjects (16.4%). Their mean age was 46.6 years (${\pm}13.5$). The mean body mass index (BMI) was 25.8 (${\pm}3.8$) and subjects with BMI was over 28.0 accounted for 22.8% of the total. Fifty subjects (6.2%) were found to take benzodiazepines. Mean RDI and mean nocturnal oxygen saturation of all subjects was 31.2 (${\pm}24.4$) and 94.5% (${\pm}3.6$), respectively. In comparison with normal values, the subjects showed longer sleep latency, lower sleep efficiency, decreased total slow wave sleep % (TSWS %), and decreased total REM sleep % (TREM %)(p<0.01 in all). RDI had a negative correlation with each TSWS % and TREM % (p<0.01, p<0.01). However, RDI did not have significant correlation with either sleep latency or sleep efficiency. Conclusion: In this study, 6.2% of patients diagnosed as having obstructive sleep apnea syndrome were found to take benzodiazepines, although they are generally considered to be of litte benefit or even dangerous because of the respiratory suppressing effect. The proportion of obese subjects was only 22.8% and Korean patients with obstructive sleep apnea syndrome seem to be less obese than those described in foreign journals. This study also suggests that the severity of obstructive sleep apnea syndrome may have a more significant effect on sleep architecture defined as TSWS % and TREM % than on sleep efficiency.
Kim, Hee-Joon;Choi, Ji-Hyang;Han, Nu-Ree;Nam, Myung-Jin;Song, Yoon-Ho;Lee, Tae-Jong;Suh, Jung-Hee
Geophysics and Geophysical Exploration
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v.8
no.4
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pp.280-286
/
2005
Geological sequestration of carbon dioxide ($CO_2$) is one of the most effective strategies far long-term removal of greenhouse gas from atmosphere. This paper reviews three projects for the $CO_2$ sequestration in geological formation. A unique $CO_2$ injection into a marine aquifer has been successfully monitored with repeated surface seismic measurements in the North Sea Sleipner West field. The seismic images reveal the extent and internal shape of the $CO_2$ bubble. Massive miscible $CO_2$ has been injected into a complex fractured carbonate reservoir at the Weyburn oil filed. High-resolution time-lapse P-wave data were successfully obtained to map the features of $CO_2$ movements within the two thin zones of different lithology. From the time-lapse crosswell EM imaging at the Lost Hills oil field in central California, U.S.A., the replacement of brine with $CO_2$ has been confirmed through a decrease of conductivity. The conductivity image was successfully compared with induction logs observed in the two wells.
Korean Journal of Agricultural and Forest Meteorology
/
v.20
no.1
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pp.135-143
/
2018
The effect of elevated temperature on temperate paddy rice will be significant for dependable food supply in East Asia. Using temperature gradient field chamber (TGFC), which was designed to make the horizontal air temperature gradient by $0^{\circ}C$ to $3^{\circ}C$ higher than outside, we examined the measurement to understand the effects of extremely high temperature on paddy rice. In particular, the data of the year 2016, the worst heat wave in over 22 years, was analyzed in this study. The rice height in the relatively warmed condition was rapidly increased during early growth stage. However, the average grain weight and number of spikelet per panicle in the warmed chamber condition were gradually declined with increasing air temperature averaged for 40 days after first heading in each chamber. In particular, the grain yield was more dramatically decreased by the raising temperature because the percent ripened grain was quickly dropped as getting over the threshold temperature for pollination. Therefore, the surplus photosynthetic product by such lower grain filling rate may disturbed the decreases of the NDVI (Normalized Difference Vegetation Index) and SPAD chlorophyll values after first (normal) heading. In addition, the late-emerging head grain were appeared. However, this yield was too small to recover the normal yields decreased by extremely high temperature condition. Our result represented that the warmed condition in 2016 would be the critical limit for the stable yield of temperate paddy rice.
We applied the seismic method to investigate the site characteristics around the Circular Pond (top diameter 7.3 m, bottom diameter 3 m, and depth 4.78 m) at the Ssangsujung Park within the Gongsansung in Gongju. Previous excavations for the cultural assets beneath the Ssangsujung Park disclosed the assumed site of the Palace of the Beakje Dynasty and the Circular Pond containing the Bakje relics. We demonstrated that the seismic prospecting can be applicable to delineate the underground structure around the cultural properties by the three kinds of seismic approaches: walk-away test, conventional refraction method, and equal-distance refraction survey. The last method which is designed by this work ran detect the I-W variations of seismic velocity in the subsurface medium across the Circular Pond on the basis of the difference of the P-wave arrival times between the 1-m-spacing 24 geophones and the corresponding 24 shots parallel with the geophone profile. From the combined results, prominent three-layer velocity structure is observed around the Circular Pond. The bottom layer is interpreted as the basement rock which is exposed near the Ssangsujung whereas the upper layer with relatively lower velocities is interpreted to be the artificial covering. The basement depth beneath the Circular Pond is deeper than the norhern area. The western basement of Circular Pond has the thicker weaker layer compared with the eastern part. Thus, the middle layer could be constructed as the artificial foundation during the Beakje Dynasty. Consequently, the Kong-sansung Circular Pond is possibly built upwardly rather than digging.
Electromagnetic waves may induce various effects on nervous tissues either by thermal or non-thermal mechanisms. This paper intoduces a method to evalute the non-thermal effect to central nervous system by measuring the EEGs of the rabbits treated by nimodipine before exposed to weak microwave field. 20 rabbits were divided into 2 groups and their EEGs were measured after their head section were exposed to 2,450 MHz microwave with the power density of 10 dBm and 20 dBm respectively for 10 minutes and compared with those of the 3rd group of 10 rabbits which were not exposed. The 4th group of 10 rabbits were intravenously given with nimodipine before exposed to 20 dBm field to determine whether this drug would reverse the EEGs changes induced by weak microwave irradiation. As field poser exceeded 20 dBm although no significant physiological changes were observed, total induced EEGs power was remarkably decreased suggesting the presence of CNS activation. Using Fourier analysis on the EEGs signal it was found that remarkable decrease in delta band and increase in the alpha and beta bands in a significant manner(P<0.05) compared to control group. The changes were, however, not reversed by nimodipine-treatment. The effects may be pure thermal in nature because no significant change has been observed in nimodipine treated rabbits.
We carried out laboratory material tests on two cements (KS-1 ordinary Portland and Class G) with changing W/S (Water/Solid) and the content of fly ash in order to evaluate their physical and mechanical properties. The specimens of KS-1 ordinary Portland cement were prepared with varying W/S (Solid=cement) in weight, while those of Class G cement were prepared with changing the content of fly ash in volume but maintaining W/S (Solid=cement+fly ash). The results of the material tests show that as the W/S in KS-1 ordinary Portland cement and the content of fly ash in Class G cement increase, the properties (density, sonic wave velocity, elastic constants, compressive and tensile strengths, thermal conductivity) decrease, but porosity and specific heat increase. In addition, an increase in confining pressure and in the content of fly ash leads to plastic failure behavior of the cements. The laboratory data were then used in a stability analysis of cement sheath for which an analytical solution for computing the stress distribution induced around a cased, cemented well was employed. The analysis was carried out with varying the injection well parameters such as thickness of casing and cement, injection pressure, dip and dip direction of injection well, and depth of injection well. The analysis results show that cement sheath is stable in the cases of relatively lower injection pressures and inclined and horizontal wells. However, in the other cases, it is damaged by mainly tensile failure.
Kim, Ji-Soo;Lee, Jae-Young;Seo, Yong-Seok;Ju, Hyeon-Tae
The Journal of Engineering Geology
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v.23
no.4
/
pp.457-465
/
2013
We integrated and correlated datasets from surface and subsurface geophysics, drilling cores, and engineering geology to identify geological interfaces and characterize the joints and fracture zones within the rock mass. The regional geometry of a geologically weak zone was investigated via a fence projection of electrical resistivity data and a borehole image-processing system. Subsurface discontinuities and intensive fracture zones within the rock mass are delineated by cross-hole seismic tomography and analyses of dip directions in rose diagrams. The dynamic elastic modulus is studied in terms of the P-wave velocity and Poisson's ratio. Subsurface discontinuities, which are conventionally identified using the N value and from core samples, can now be identified from anomalous reflection coefficients (i.e., acoustic impedance contrast) calculated using a pair of well logs, comprising seismic velocity from suspension-PS logging and density from logging. Intensive fracture zones identified in the synthetic seismogram are matched to core loss zones in the drilling core data and to a high concentration of joints in the borehole imaging system. The upper boundaries of fracture zones are correlated to strongly negative amplitude in the synthetic trace, which is constructed by convolution of the optimal Ricker wavelet with a reflection coefficient. The standard deviations of dynamic elastic moduli are higher for fracture zones than for acompact rock mass, due to the wide range of velocities resulting from the large numbers of joints and fractures within the zone.
Park, Sung-Ae;Kong, Hak-Yang;Kim, Seung-Hyun;Park, Sungmin;Shin, Young-Kyu
Ecology and Resilient Infrastructure
/
v.3
no.1
/
pp.46-53
/
2016
This study was conducted to analyze the effect of the different land covers of an urban park (Hyowon park) in downtown Suwon on the urban thermal variations during a hot summer. The effect of the air temperature reduction in the urban park was 4.4%-4.5% for the downtown residence (Maetan-dong). This value was about 0.8% lower than that of the outskirts residence (Sanggwanggyo-dong). The daily mean temperature, daily maximum temperature, summer day and heat wave frequency were measured under the different land covers (cement-block, grass, pine-grass, shading area and mixed forest) showed these values generally decreased under natural land cover types. Daily minimum temperature and tropical night frequency didn't seem to correlate with the land cover types. Means of thermal comfort indices (wet bulb globe temperature, heat index and discomfort index) in the shading area, mixed forest and the pine-grass types were lower than those of cement block and grass types. However the levels of those indices were equal to 'very high' or 'caution' levels in the afternoon (13:00-15:00). In the morning (06:00-08:00), thermal comfort indices of the urban park didn't correlate with land cover types. Therefore, to reduce heat stress and to improve the thermal comfort in urban parks, an increase in the area of natural land cover such as grass, forest and open spaces is required.
DC electrical and electromagnetic survey was applied to evaluate the reserve of an iron mine site. We analyzed the borehole cores and the cores sampled from outcrops in order to decide which geophysical method was efficient for the evaluation of iron mine site and to understand the geological setting around the target area. Based on the core tests for specific weight, density, porosity, resistivity and P-wave velocity, showing that the magnetite could be distinguishable by the electrical property, we decided to conduct the electrical survey to investigate the irone mine site. According to previous studies, the DC electrical survey was known to have various arrays with high resolutions effective to the survey of the iron mine site. However it was also known that the skin depth is too shallow to grasp the deep structure of iron mine. To compensate the weakness of the DC electrical method, we applied the MagnetoTelluric (MT) survey. In addition, a Controlled Source MT (CSMT) method was also applied to make up the shortcoming of MT method which is weak for shallow targets. From the DC electrical and MT survey, we found a new low resistivity zone, which is believed to be a magnetite reserve beneath the old abandoned mine. Therefore, this study was confirmed for additional utility value.
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