• 제목/요약/키워드: P generation

검색결과 2,190건 처리시간 0.029초

만성요통환자와 정상인의 요부신전근의 등척성 근력 평가 (Isometric evaluation of the Lumbar extensors in Choronic Low Back Pain Patients and Healthy subjects)

  • 임창훈
    • The Journal of Korean Physical Therapy
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    • 제14권1호
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    • pp.169-176
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    • 2002
  • The purpose of this study were to measured peak torque of lumbar extensor at various degrees and to compare with the choronic low back pain patients and healthy subjects back extensor peak torque. Research subject are fifty choronic low back pain patients and fifty healthy subjects are Dong-a university hospital visited to 2000, January since 1999, august none lumbosacral traumal past history and neurologic disorder that is twenty generation, thirty generation, forty generation, fifty generation, sixty generation in healthy subjects and twenty generation, thirty generation, forty generation, fifty generation, sixty generation in cause choronic low back pain patients. The result were as follows. 1. There were each generation choronic low back pain patients and healthy subjects back extensor peak torque are consideration (p<.05). 2. Twenty generation was all degree of angle in lumbar extention peak torque in choronic low back pain patients back extensor are lower than healthy subjects(p<.05). 3. Thirty generation was all degree of angle in lumbar extention peak torque in choronic low back pain patients back extensor are lower than healthy subjects(p<.05). 4. Forty generation was all degree of angle in lumbar extention peak torque in choronic low back pain patients back extensor are lower than healthy subjects(p<;.05). 5. Fifty generation was all degree of angle in lumbar extention peak torque in choronic low back pain patients back extensor are lower than healthy subjects(p<.05). 6. Sixty generation was all degree of angle in lumbar extention peak torque in choronic low back pain patients back extensor are lower than healthy subjects(p<.05).

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Sociodemographic and Health Related Factors Influencing Problem Drinking of the Echo Generation Using Data of the 2018 Korean National Health and Nutrition Examination Survey

  • Kwak, Minyeong
    • International Journal of Contents
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    • 제17권1호
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    • pp.54-60
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    • 2021
  • The aim of this study was to identify factors influencing problem drinking among the Echo Generation in South Korea and provide basic data for early intervention and mediation of problem drinking among the Echo Generation. This descriptive study performed a secondary analysis of raw data from the 2018 Korean National Health and Nutrition Examination Survey and used responses for problem drinking items from 999 Echo Generation participants born between 1979 and 1992. This study comprehensively investigated sociodemographic and health-related factors influencing problem drinking among the Echo Generation. SPSS WIN program (version 26.0) was used for data analysis. Gender (β=-.32, p<.001), education level (β=.10, p=.002), white-collar workers out of job (β=-.09, p=.041), and depression (β=.11, p<.001) were identified as factors that influenced problem drinking among the Echo Generation. Results of this study suggest that in order to prevent problem drinking among the Echo Generation, there should be user-customized prevention education and intervention programs.

Co-Ni-P-B/Ni foam 촉매에서 $NaBH_4$ 가수분해를 통한 수소 발생 (Hydrogen Generation from $NaBH_4$ Hydrolysis on Co-Ni-P-B/Ni Foam Catalyst)

  • 박대일;김태규
    • 한국수소및신에너지학회논문집
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    • 제21권5호
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    • pp.383-389
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    • 2010
  • Co-B, Co-P-B, Co-Ni-B and Co-Ni-P-B catalysts supported on Ni foam were prepared using electroless plating in the present study. The surface morphology of the catalysts/Ni foam was observed using SEM and EDS analysis. The Co-Ni-P-B/Ni foam catalyst showed the superior performance on hydrogen generation due to the uniform formation of catalyst particles on the Ni foam surface. The characteristics of hydrogen generation with Co-Ni-P-B/Ni foam catalyst was investigated at the variety of $NaBH_4$ and NaOH concentrations. Durability test was performed, resulting in the stable hydrogen generation for 6 hours.

Modulation of Multidrug Resistance in Cancer by P-Glycoprotein

  • Gadhe, Changdev G.;Cho, Seung Joo
    • 통합자연과학논문집
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    • 제4권1호
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    • pp.23-30
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    • 2011
  • Multidrug resistance (MDR) is one of the main obstacles in the chemotherapy of cancer. MDR is associated with the over expression of P-glycoprotein (P-gp), resulting in increased efflux of chemotherapy from cancer cells. Inhibiting P-gp as a method to reverse MDR in cancer patients has been studied extensively, but the results have generally been disappointing. First-generation agents were limited by unacceptable toxicity, whereas second-generation agents had better tolerability but were confounded by unpredictable pharmacokinetic interactions and interactions with other transporter proteins. Third-generation inhibitors have high potency and specificity for P-gp. Furthermore, pharmacokinetic studies to date have shown no appreciable impact on drug metabolism and no clinically significant drug interactions with common chemotherapy agents. Third-generation P-gp inhibitors have shown promise in clinical trials. The continued development of these agents may establish the true therapeutic potential of P-gp-mediated MDR reversal.

KOREAN STUDENTS' BEHAVIORAL CHANGE TOWARD NUCLEAR POWER GENERATION THROUGH EDUCATION

  • Han, Eun Ok;Kim, Jae Rok;Choi, Yoon Seok
    • Nuclear Engineering and Technology
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    • 제46권5호
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    • pp.707-718
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    • 2014
  • As a result of conducting a 45 minute-long seminar on the principles, state of use, advantages, and disadvantages of nuclear power generation for Korean elementary, middle, and high school students, the levels of perception including the necessity (p<0.017), safety (p<0.000), information acquisition (p<0.000), and subjective knowledge (p<0.000), objective knowledge (p<0.000), attitude (p<0.000), and behavior (p<0.000) were all significantly higher. This indicates that education can be effective in promoting widespread social acceptance of nuclear power and its continued use. In order to induce behavior change toward positive judgments on nuclear power generation, it is necessary to focus on attitude improvement while providing the information in all areas related to the perception, knowledge, attitude, and behavior. Here, the positive message on the convenience and the safety of nuclear power generation should be highlighted.

노화촉진 생쥐에서 노화에 따른 활성산소 생성 및 항산화능의 변화 (Age-associated Alteration in the Hapatic Superoxide Generation and Antioxidant Activities in the Senescence-accelerated Mice)

  • 정해영;김윤경
    • 약학회지
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    • 제36권5호
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    • pp.460-468
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    • 1992
  • Several bichemical parameters related to free radicals were estimated in senile-prone (P) and resistant(R) strains of male senescence-accelerated mice(SAM) at 2, 5 and 11 months of age. The superoxide generation was increased with age in SAM-R/1 and SAM-P/2. Compared to SAM-R/1, more generation of superoxide was significantly noted in the SAM-P/2 liver. The activities of Cu/Zn-superoxide dismutase and catalase were decreased during aging and these activities in SAM-P/2 were significantly lower than in SAM-R/l liver. The activities of glutathione S-transferase were varied with aging, whereas SAM-P/2 showed lower levels compared to SAM-R/l. The gradual decreases of glutathione, protein bound-SH and nonprotein bound-SH contents were noted with increasing age. SAM-P/2 liver contained lesser amounts of glutathione and nonprotein bound-SH compared to SAM-R. In conclusion, superoxide generation was increased whereas the antioxidant enzyme activities were decreased during aging in SAM-R/1. In addition, SAM-P/2 strain showed more superoxide generation and less antioxidant enzyme activities than SAM-R/1 in the liver, thus we assume that these factors might accelerate the senescence of SAM-P/2 strain.

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초, 중, 고등학생의 방사선조사식품, 원자력발전, 의료방사선에 대한 인식, 지식, 태도 차이 (Different Perceptions, Knowledge, and Attitudes of Elementary, Middle, and High School Students regarding Irradiated Food, Nuclear Power Generation, and Medical Radiation)

  • 한은옥;김재록;최윤석
    • Journal of Radiation Protection and Research
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    • 제39권2호
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    • pp.118-126
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    • 2014
  • 향후 여론의 주도층이 될 일부 초, 중, 고등학생을 대상으로 방사선이용 분야 중 일반적으로 사회적 수용성이 절실히 필요한 방사선조사식품, 원자력발전, 의료방사선에 대한 인식, 지식 및 태도를 설문 조사한 결과 사회적 수용성 증진을 위한 교육적 근거가 일부 도출되었다. 첫째, 여학생 중심의 수업과 남학생 중심의 수업설계에 차별화된 전략이 필요하다. 여학생 보다 남학생이 방사선조사식품의 객관적 지식수준(p<0.039), 원자력발전의 필요성(p<0.001) 및 객관적 지식(p<0.001), 우리나라 원자력발전소 건설 찬성태도 (p<0.000), 의료방사선의 필요성(p<0.001) 및 객관적 지식(p<0.001), 의료방사선 이용 태도(p<0.007, p<0.001)가 모두 높기 때문이다. 둘째, 원자력발전의 필요성, 안전성에 대한 국민 이해를 돕기 위한 설명에서는 의료방사선의 필요성과 안전성에 대한 정보를 함께 제공하는 것이 교육효과를 높일 수 있다. 남, 여학생 모두 의료방사선이 가장 필요하며(p<0.001), 의료방사선이 가장 안전하며(p<0.001), 원자력 발전이 가장 안전하지 않다고(p<0.013) 인식하고 있다. 또한 의료방사선과 원자력 발전의 상관관계가 가장 높게 나타났기 때문이다. 셋째, 초, 중, 고등학생이 방사선이용 분야별로 인식의 패턴이 다르므로 학급별로 차별화된 강의내용이 필요하다. 초등학생은 원자력발전에 대한 교육흥미도가 높고(p<0.005), 방사선조사식품이 안전하다고 인식하고 있으며(p<0.001), 방사선조사식품을 섭취하겠다는 태도가 가장 높았다(p<0.001). 중학생은 의료방사선에 대한 교육흥미도가 높고(p<0.018), 원자력발전(p<0.001)과 의료방사선(p<0.002)에 대해 안전하다고 인식하고 있으며, 치료 방사선이용 태도가 가장 높았다(p<0.001). 고등학생은 원자력발전(p<0.001)과 의료방사선(p<0.001)에 대한 객관적 지식수준이 가장 높고, 의료방사선이 가장 필요하다고 인식하고 있으나(p<0.017), 원자력발전이 가장 안전하지 않다고 인식하고 있다(p<0.001). 방사선조사식품 섭취 태도(p<0.001), 거주지에 원자력발전 건설을 찬성하는 태도(p<0.001) 모두 낮았다. 넷째, 객관적 지식 중심의 교육제공보다 인식변화 및 태도증진을 위한 교육프로그램이 제공되어야 한다. 객관적 지식과 방사선조사식품의 필요성, 객관적 지식과 원자력발전에 대한 안전성 및 교육흥미도, 객관적 지식과 의료방사선의 교육흥미도 및 정보습득에는 상관관계가 없었다. 특히, 고등학생의 경우 객관적 지식수준은 가장 높았으나 거주지의 원자력발전 건설에 대해 찬성하는 태도와 방사선조사식품 섭취태도가 가장 낮았기 때문이다. 국내에서 원자력 및 방사선이용에 대한 사회적 수용성을 향상시키기 위해 필요성과 안전성에 대한 인식과 지식 및 태도 향상에 관한 교육프로그램을 전략적으로 제공하는 것이 바람직하다.

디젤발전 자켓냉각시스템 열성능 향상 연구 (Performance Research of a Jacket Cooling Water System in a Diesel Electric Generation)

  • 이재근;문전수;윤석원;박필양
    • 한국수소및신에너지학회논문집
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    • 제20권6호
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    • pp.534-539
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    • 2009
  • One of the most efficient techniques improving the heat transfer performance of a diesel electric generation is a corrosion control in jacket cooling water system. The environmental parameters most affecting corrosion are dissolved salt concentration, temperature, and pH of cooling water. No corrosion occurs in carbon steel probe at pH 11 in normal operating condition of diesel electric generation cooling water. pH control agent in this study is trisodium phosphate. pH control appears to be the most convenient way to enhance the thermal performance of a diesel electric generation.

오존산화공정에서 수산화라디칼(OH.)의 생성속도 측정 (The estimation of Hydroxyl radical generation rate in Ozonation)

  • 권충일;공성호;배성렬
    • 한국지하수토양환경학회지:지하수토양환경
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    • 제6권1호
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    • pp.3-12
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    • 2001
  • 오존산화공정에서 수산화라디칼(OH.)의 생성속도가 다양한 실험조건(오존의 주입농도, 니트로벤젠의 농도, scavenger, pH, 과산화수소)에서 측정되었다. 니트로벤젠은 오존과의 직접적인 반응보다는 수산화라디칼에 의해 분해되었으며 분해속도는 오존과 니트로벤젠의 농도의 함수로 표현되었다. 또한 수산화라디칼 scavenger의 농도가 증가할수록 반응속도는 감소하였다. 실험상에서 얻은 모든 결과는 일차반응속도식을 따랐다. Probe compound와 scavenger를 이용한 경쟁적 방법을 사용하여 수산화라디칼을 측정하였는데, 그 결과 수산화라디칼의 생성속도는 오존의 농도에 선형적으로 비례하였으며, 오존 1몰당 수산화라디칼은 0.24몰이 생성되었다. 동일 오존농도에서 pH의 변화에 따른 수산화라디칼의 생성속도가 측정되었으며, (pH 10.2 ($0.91Ms^{-1}$) > pH 7.3($0.72Ms^{-1}$) > pH 5.6($0.67Ms^{-1}$) > pH 3.4($0.63Ms^{-1}$)) 중성이하의 pH에서보다 알칼리성 pH에서 수산화라디칼은 많이 발생됨을 알 수 있다. 또한 과산화수소의 첨가도 수산화라디칼의 생성속도를 증진시키는 결과를 낳았다. pH의 조절과 과산화수소의 첨가시 발생속도를 비교해보면 과산화수소를 첨가했을 때 수산화라디칼의 발생속도는 1.6배정도 더 크게 측정되었는데 이는 수산화라디칼을 발생시키는 데 있어서 과산화수소의 첨가가 pH의 조절보다는 더 좋은 증진제로써 작용할 수 있다는 것을 설명해준다. 이러한 결과들은 오염된 토양이나 지하수를 처리하기 위한 오존을 이용한 고급산화공정에 충분히 적용될 수 있을 것이라 판단된다.

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알칼리 $NaBH_4$ 용액의 수소발생특성에 미치는 Co-P 촉매의 영향 (Effects of Co-P Catalysts on Hydrogen Generation Properties from Alkaline $NaBH_4$ Solution)

  • 조근우;권혁상
    • 한국수소및신에너지학회논문집
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    • 제16권4호
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    • pp.379-385
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    • 2005
  • Effects of Co and Co-P catalysts on the hydrolysis of alkaline $NaBH_4$ solution were investigated. Co and Co-P catalysts were prepared on Cu substrate by electroplating. Hydrogen generation rate of Co-P catalyst was much faster than that of Co catalyst, demonstrating that Co-P had higher intrinsic catalytic activity for the hydrolysis of $NaBH_4$ than Co. Hydrogen generation properties of Co-P catalysts largely depended on cathodic current density and electroplating time because they influenced on the P concentration of the Co-P catalysts. Maximum hydrogen generation rate of Co-P catalyst was 1066 ml/min.g-catalyst in 1 wt.% NaOH + 10 wt.% $NaBH_4$ solution at $20^{\circ}C$, which was obtained at cathodic current density of $0.01\;A/cm^2$ for 130 s.