• Title/Summary/Keyword: P generation

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Isometric evaluation of the Lumbar extensors in Choronic Low Back Pain Patients and Healthy subjects (만성요통환자와 정상인의 요부신전근의 등척성 근력 평가)

  • Lim, Chang-Hun
    • The Journal of Korean Physical Therapy
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    • v.14 no.1
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    • pp.169-176
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    • 2002
  • The purpose of this study were to measured peak torque of lumbar extensor at various degrees and to compare with the choronic low back pain patients and healthy subjects back extensor peak torque. Research subject are fifty choronic low back pain patients and fifty healthy subjects are Dong-a university hospital visited to 2000, January since 1999, august none lumbosacral traumal past history and neurologic disorder that is twenty generation, thirty generation, forty generation, fifty generation, sixty generation in healthy subjects and twenty generation, thirty generation, forty generation, fifty generation, sixty generation in cause choronic low back pain patients. The result were as follows. 1. There were each generation choronic low back pain patients and healthy subjects back extensor peak torque are consideration (p<.05). 2. Twenty generation was all degree of angle in lumbar extention peak torque in choronic low back pain patients back extensor are lower than healthy subjects(p<.05). 3. Thirty generation was all degree of angle in lumbar extention peak torque in choronic low back pain patients back extensor are lower than healthy subjects(p<.05). 4. Forty generation was all degree of angle in lumbar extention peak torque in choronic low back pain patients back extensor are lower than healthy subjects(p<;.05). 5. Fifty generation was all degree of angle in lumbar extention peak torque in choronic low back pain patients back extensor are lower than healthy subjects(p<.05). 6. Sixty generation was all degree of angle in lumbar extention peak torque in choronic low back pain patients back extensor are lower than healthy subjects(p<.05).

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Sociodemographic and Health Related Factors Influencing Problem Drinking of the Echo Generation Using Data of the 2018 Korean National Health and Nutrition Examination Survey

  • Kwak, Minyeong
    • International Journal of Contents
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    • v.17 no.1
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    • pp.54-60
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    • 2021
  • The aim of this study was to identify factors influencing problem drinking among the Echo Generation in South Korea and provide basic data for early intervention and mediation of problem drinking among the Echo Generation. This descriptive study performed a secondary analysis of raw data from the 2018 Korean National Health and Nutrition Examination Survey and used responses for problem drinking items from 999 Echo Generation participants born between 1979 and 1992. This study comprehensively investigated sociodemographic and health-related factors influencing problem drinking among the Echo Generation. SPSS WIN program (version 26.0) was used for data analysis. Gender (β=-.32, p<.001), education level (β=.10, p=.002), white-collar workers out of job (β=-.09, p=.041), and depression (β=.11, p<.001) were identified as factors that influenced problem drinking among the Echo Generation. Results of this study suggest that in order to prevent problem drinking among the Echo Generation, there should be user-customized prevention education and intervention programs.

Hydrogen Generation from $NaBH_4$ Hydrolysis on Co-Ni-P-B/Ni Foam Catalyst (Co-Ni-P-B/Ni foam 촉매에서 $NaBH_4$ 가수분해를 통한 수소 발생)

  • Park, Da-Ill;Kim, Tae-Gyu
    • Journal of Hydrogen and New Energy
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    • v.21 no.5
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    • pp.383-389
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    • 2010
  • Co-B, Co-P-B, Co-Ni-B and Co-Ni-P-B catalysts supported on Ni foam were prepared using electroless plating in the present study. The surface morphology of the catalysts/Ni foam was observed using SEM and EDS analysis. The Co-Ni-P-B/Ni foam catalyst showed the superior performance on hydrogen generation due to the uniform formation of catalyst particles on the Ni foam surface. The characteristics of hydrogen generation with Co-Ni-P-B/Ni foam catalyst was investigated at the variety of $NaBH_4$ and NaOH concentrations. Durability test was performed, resulting in the stable hydrogen generation for 6 hours.

Modulation of Multidrug Resistance in Cancer by P-Glycoprotein

  • Gadhe, Changdev G.;Cho, Seung Joo
    • Journal of Integrative Natural Science
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    • v.4 no.1
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    • pp.23-30
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    • 2011
  • Multidrug resistance (MDR) is one of the main obstacles in the chemotherapy of cancer. MDR is associated with the over expression of P-glycoprotein (P-gp), resulting in increased efflux of chemotherapy from cancer cells. Inhibiting P-gp as a method to reverse MDR in cancer patients has been studied extensively, but the results have generally been disappointing. First-generation agents were limited by unacceptable toxicity, whereas second-generation agents had better tolerability but were confounded by unpredictable pharmacokinetic interactions and interactions with other transporter proteins. Third-generation inhibitors have high potency and specificity for P-gp. Furthermore, pharmacokinetic studies to date have shown no appreciable impact on drug metabolism and no clinically significant drug interactions with common chemotherapy agents. Third-generation P-gp inhibitors have shown promise in clinical trials. The continued development of these agents may establish the true therapeutic potential of P-gp-mediated MDR reversal.

KOREAN STUDENTS' BEHAVIORAL CHANGE TOWARD NUCLEAR POWER GENERATION THROUGH EDUCATION

  • Han, Eun Ok;Kim, Jae Rok;Choi, Yoon Seok
    • Nuclear Engineering and Technology
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    • v.46 no.5
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    • pp.707-718
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    • 2014
  • As a result of conducting a 45 minute-long seminar on the principles, state of use, advantages, and disadvantages of nuclear power generation for Korean elementary, middle, and high school students, the levels of perception including the necessity (p<0.017), safety (p<0.000), information acquisition (p<0.000), and subjective knowledge (p<0.000), objective knowledge (p<0.000), attitude (p<0.000), and behavior (p<0.000) were all significantly higher. This indicates that education can be effective in promoting widespread social acceptance of nuclear power and its continued use. In order to induce behavior change toward positive judgments on nuclear power generation, it is necessary to focus on attitude improvement while providing the information in all areas related to the perception, knowledge, attitude, and behavior. Here, the positive message on the convenience and the safety of nuclear power generation should be highlighted.

Age-associated Alteration in the Hapatic Superoxide Generation and Antioxidant Activities in the Senescence-accelerated Mice (노화촉진 생쥐에서 노화에 따른 활성산소 생성 및 항산화능의 변화)

  • Chung, Hae-Young;Kim, Yun-Kyung
    • YAKHAK HOEJI
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    • v.36 no.5
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    • pp.460-468
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    • 1992
  • Several bichemical parameters related to free radicals were estimated in senile-prone (P) and resistant(R) strains of male senescence-accelerated mice(SAM) at 2, 5 and 11 months of age. The superoxide generation was increased with age in SAM-R/1 and SAM-P/2. Compared to SAM-R/1, more generation of superoxide was significantly noted in the SAM-P/2 liver. The activities of Cu/Zn-superoxide dismutase and catalase were decreased during aging and these activities in SAM-P/2 were significantly lower than in SAM-R/l liver. The activities of glutathione S-transferase were varied with aging, whereas SAM-P/2 showed lower levels compared to SAM-R/l. The gradual decreases of glutathione, protein bound-SH and nonprotein bound-SH contents were noted with increasing age. SAM-P/2 liver contained lesser amounts of glutathione and nonprotein bound-SH compared to SAM-R. In conclusion, superoxide generation was increased whereas the antioxidant enzyme activities were decreased during aging in SAM-R/1. In addition, SAM-P/2 strain showed more superoxide generation and less antioxidant enzyme activities than SAM-R/1 in the liver, thus we assume that these factors might accelerate the senescence of SAM-P/2 strain.

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Different Perceptions, Knowledge, and Attitudes of Elementary, Middle, and High School Students regarding Irradiated Food, Nuclear Power Generation, and Medical Radiation (초, 중, 고등학생의 방사선조사식품, 원자력발전, 의료방사선에 대한 인식, 지식, 태도 차이)

  • Han, Eun Ok;Kim, Jae Rok;Choi, Yoon Seok
    • Journal of Radiation Protection and Research
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    • v.39 no.2
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    • pp.118-126
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    • 2014
  • A survey was conducted on perceptions, knowledge, and attitudes of elementary, middle, and high school students, who will lead public opinion in the future, regarding irradiated food, nuclear power generation, and medical radiation. These topics urgently require general social acceptability among various fields in which radiation is used. Educational methods to enhance social acceptability were partially discovered. First, it is necessary to implement different strategies when designing courses for female and male students. Male students have higher levels of objective knowledge (p<0.039) of irradiated food, necessity (p<0.001) and objective knowledge (p<0.001) of nuclear power generation, approval of building a nuclear power plant in the nation (p<0.001), necessity (p<0.001) and objective knowledge (p<0.001) of medical radiation, and attitudes regarding using medical radiation (p<0.007, p<0.001). Second, the educational effect of explanations to help increase national understanding of the necessity and safety of nuclear power generation will increase if information on the necessity and safety of medical radiation is provided as well. Both male and female students perceived that medical radiation is the most necessary (p<0.001), medical radiation is the safest (p<0.001), and nuclear power generation is the least safe (p<0.013). Moreover, the correlation between medical radiation and nuclear power generation was the highest. Third, there is a need for different lectures between classes, since the patterns of perception vary according to the field of radiation use among elementary, middle, and high school students. Elementary school students had high interest in education on nuclear power generation (p<0.005), perceived that irradiated food is safe (p<0.001), and had the most positive attitude toward consuming irradiated food (p<0.001). Middle school students had high interest in education on nuclear power generation (p<0.018), perceived that nuclear power generation (p<0.001) and medical radiation (p<0.002) are safe, and had the most positive attitude toward using radiation for treatment (p<0.001). High school students had the highest level of objective knowledge on nuclear power generation (p<0.001) and medical radiation (p<0.001), and perceived that medical radiation is the most necessary (p<0.017); however, they perceived that nuclear power generation is the least safe (p<0.001). Attitudes toward irradiated food intake (p<0.001) and approving construction of a nuclear power plant in their neighborhood (p<0.001) were both low. Fourth, it is necessary to provide educational programs to change perceptions and improve attitudes rather than providing education focused on objective knowledge. There was no correlation between objective knowledge and necessity of irradiated food, objective knowledge and safety and interest in education on nuclear power generation, and objective knowledge and interest in education and information acquirement regarding medical radiation. In particular, high school students had the highest level of objective knowledge and yet had the least positive attitudes toward approving construction of nuclear power plants in their neighborhood and intake of irradiated food. Therefore, to increase the social acceptability of using nuclear energy and radiation in Korea, it is desirable to provide strategic educational programs to improve perceptions, knowledge, and attitudes regarding the necessity and safety of their use.

The estimation of Hydroxyl radical generation rate in Ozonation (오존산화공정에서 수산화라디칼(OH.)의 생성속도 측정)

  • 권충일;공성호;배성렬
    • Journal of Soil and Groundwater Environment
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    • v.6 no.1
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    • pp.3-12
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    • 2001
  • During ozonation process, the hydroxyl radical generation rates were measured under different experimental conditions (ozone feed rate, nitrobenzene concentration, hydroxyl radical scavenger, pH, HO$_2$O$_2$/O$_3$ etc.) Nitrobenzene could be decomposed by hydroxyl radical rather than ozone only and nitrobenzene decomposition rate was expressed with functions of ozone and nitrobenzene concentration. The rate was decreased as the hydroxyl radical scavenger concentration was increased, and all results were followed pseudo first-order reaction. Using a competitive method, hydroxyl radical generation rate was measured with probe compound and scavenger. It was proportional to ozone concentration, and 0.24mo1 of hydroxyl radical was produced with 1mol of ozone. Under different pH conditions, hydroxyl radical generation rates were measured (pH 10.2 (0.91Ms$^{-1}$ ) > pH 7.3 (0.72Ms$^{-1}$ ) > pH 5.6 (0.67Ms$^{-1}$ ) > pH 3.4 (0.63Ms$^{-1}$ )) showing higher generation rate at high pH values. Addition of hydrogen peroxide promoted the generation rate of hydroxyl radical. Considering the results of pH experiments and addition of hydrogen peroxide experiments, the hydroxyl radical generation rate was 1.6 times higher in hydrogen peroxide solution than in high pH solution, indicating addition of hydrogen peroxide is better promoter to produce the hydroxyl radical in ozonation. These results could be applied to AOPs to remediate the contaminated wastewater and groundwater.

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Performance Research of a Jacket Cooling Water System in a Diesel Electric Generation (디젤발전 자켓냉각시스템 열성능 향상 연구)

  • Lee, Jae-Keun;Moon, Jeon-Soo;Yoon, Seok-Won;Park, Pill-Yang
    • Journal of Hydrogen and New Energy
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    • v.20 no.6
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    • pp.534-539
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    • 2009
  • One of the most efficient techniques improving the heat transfer performance of a diesel electric generation is a corrosion control in jacket cooling water system. The environmental parameters most affecting corrosion are dissolved salt concentration, temperature, and pH of cooling water. No corrosion occurs in carbon steel probe at pH 11 in normal operating condition of diesel electric generation cooling water. pH control agent in this study is trisodium phosphate. pH control appears to be the most convenient way to enhance the thermal performance of a diesel electric generation.

Effects of Co-P Catalysts on Hydrogen Generation Properties from Alkaline $NaBH_4$ Solution (알칼리 $NaBH_4$ 용액의 수소발생특성에 미치는 Co-P 촉매의 영향)

  • Cho, Keun-Woo;Kwon, Hyuk-Sang
    • Journal of Hydrogen and New Energy
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    • v.16 no.4
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    • pp.379-385
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    • 2005
  • Effects of Co and Co-P catalysts on the hydrolysis of alkaline $NaBH_4$ solution were investigated. Co and Co-P catalysts were prepared on Cu substrate by electroplating. Hydrogen generation rate of Co-P catalyst was much faster than that of Co catalyst, demonstrating that Co-P had higher intrinsic catalytic activity for the hydrolysis of $NaBH_4$ than Co. Hydrogen generation properties of Co-P catalysts largely depended on cathodic current density and electroplating time because they influenced on the P concentration of the Co-P catalysts. Maximum hydrogen generation rate of Co-P catalyst was 1066 ml/min.g-catalyst in 1 wt.% NaOH + 10 wt.% $NaBH_4$ solution at $20^{\circ}C$, which was obtained at cathodic current density of $0.01\;A/cm^2$ for 130 s.