• 제목/요약/키워드: P candidates

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후보자 이미지 형성에 관한 미디어의 차별적 효과와 미디어 이용, 대인커뮤니케이션, 투표참여 간의 상호관계에 관한 연구 (Differential Media Effects on Candidates' Image and Correlations Among Media Use, Interpersonal Communication, and Voting Participation)

  • 김진영
    • 한국언론정보학보
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    • 제32권
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    • pp.113-146
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    • 2006
  • 본 연구에서는 미디어 이용과 선거캠페인의 이용이 투표참여에 어떤 영향을 미치는지를 분석하기 위해 1) 지역미디어이용과 주의 깊은 선거캠페인 이용이 대인커뮤니케이션과 투표참여에 영향을 끼쳤는가 2) 주의 깊은 선거캠페인에서 형성된 후보자 이미지가 투표에 영향을 미쳤는가, 또, 정당요인이 크게 작용하는 지방선거에서 정당요인과 이미지요인이 투표에 어떤 영향을 가지는가 그리고 3) 각기 다른 매체들은 후보자 이미지가 형성되는 과정에서 어떤 차별적 역할을 하는가를 검토해보았다. 연구 결과, 주의 깊은 정치캠페인 이용과 지역신문 이용은 대인커뮤니케이션의 증가를 가져왔고, 또 대인커뮤니케이션을 많이 하면 할수록, 투표참여가 높았음이 경로분석에서 드러났다. 즉, 정치참여에서 대인커뮤니케이션은 미디어로부터 얻어진 정보를 처리하는 과정에서 중요한 역할을 하는 보완적 관계임이 확인되었다. 또, 투표참여의 중요한 세 변인인 이슈, 이미지, 정당 가운데, 이미지와 정당요인이 후보자 결정에 미치는 영향을 비교분석한 결과, 정당지지와 후보 결정 간에는 높은 상관관계를 발견했지만, 후보자 이미지가 후보결정이나 투표참여로는 연결되지 못하는 것으로 나타나, 이미지 요인과 정당 요인 중 후보결정에는 정당 요인이 더 큰 영향력을 발휘했다. 또, 유권자들은 자신이 이미 선호하고 있는 정당지지성향에 따라, 상대정당 후보보다 자신의 지지정당 후보의 이미지를 모든 요인에서 높게 평가하는 경향이 있어, 인지균형이론의 적용을 보여주었다. 후보자 이미지에 대한 미디어의 차별적 효과는 부분적으로 증명이 되었다. 즉, 후보자의 이미지 중, 능력 요인은 TV 토론회, 인터넷 홈페이지, 홍보책자를 각각 주의 깊게 이용한 실험집단 간에 통계학적으로 유의미한 차이를 보였다.성연구의 차별적으로 기여하는 점은 기존의 연구는 기업의 명성을 측정할 수 있는 측정문항개발에 초점을 맞추었는데 비해서 실제 국내에서 명성을 축적한 기업을 대상으로 명성측정을 개별적으로 적용함으로써 각 기업의 명성을 계량화하고 명성을 구성하는 차원이 실제 명성에 어떻게 기여했는지에 대해서 파악했다는 점이다. 이는 실무적으로 보았을 때 홍보담당자가 자신의 기업홍보활동이 기업명성에 어떻게 기여할 수 있는가를 파악하고 경쟁기업의 홍보활동에 비해서 얼마만큼 효율적이었는지에 대한 평가기준을 제시할 수 있음을 의미하는 것이다.어에 대한 차별성 내지 특수성에 기인하는 동기들에 비해 전체적으로 강하다. 또한 기존 이론과 연구들에서 유의미한 이동전화 이용의 요인으로 제기된 사회심리적 특성들은 조사대상인 청소년들에 있어서도 큰 차이 없이 일반화가 가능한 것으로 보이며, 그 중에서도 "혁신성"과 "타인지향성"이 미치는 영향이 주목된다.X>62mL, 부분반응군 330${\pm}$136mL, 무반응군 140${\pm}$43mL, 야간 다뇨는 각각 59.3$\%$(16/27), 40.7$\%$(11/27), 0$\%$(0/27)로 야간 요량이 많을수록 유의하게 치료 효과가 좋았다(P<0.05). 일회 최대 요량은 완전반응군 236${\pm}$42 mL, 부분반응군 209${\pm}$56 mL, 무반응군 107${\pm}$36mL로 최대 요량이 많을수록 유의하게 치료 효과가 좋았다 (p<0.05). 연령, 성별, 일일 수분 섭취량, 다음, 일일 요량과 다뇨은 세 군간에 유의한 차이가 없었다. 야간 수분

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Bacterial Community of Galchi-Baechu Kimchi Based on Culture-Dependent and - Independent Investigation and Selection of Starter Candidates

  • Kim, Tao;Heo, Sojeong;Na, Hong-Eun;Lee, Gawon;Kim, Jong-Hoon;Kwak, Mi-Sun;Sung, Moon-Hee;Jeong, Do-Won
    • Journal of Microbiology and Biotechnology
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    • 제32권3호
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    • pp.341-347
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    • 2022
  • In this study, the bacterial community of galchi-baechu kimchi was determined using culture-based and culture-independent techniques (next generation sequencing:NGS), and showed discrepancies between results. Weissella koreensis and Pediococcus inopinatus were the dominant species according to the NGS results, while Bacillus species and P. inopinatus were dominant in the culture-dependent analysis. To identify safe starter candidates, sixty-five Bacillus strains isolated from galchi-baechu kimchi using culture-dependent methods were evaluated for their antibiotic resistance, presence of toxin genes, and hemolytic activity. Strains were then assessed for salt tolerance and protease and lipase activity. As a result, four strains-B. safensis GN5_10, B. subtilis GN5_19, B. velezensis GN5_25, and B. velezensis GT8-were selected as safe starter candidates for use in fermented foods.

Identification and Validation of Circulating MicroRNA Signatures for Breast Cancer Early Detection Based on Large Scale Tissue-Derived Data

  • Yu, Xiaokang;Liang, Jinsheng;Xu, Jiarui;Li, Xingsong;Xing, Shan;Li, Huilan;Liu, Wanli;Liu, Dongdong;Xu, Jianhua;Huang, Lizhen;Du, Hongli
    • Journal of Breast Cancer
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    • 제21권4호
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    • pp.363-370
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    • 2018
  • Purpose: Breast cancer is the most commonly occurring cancer among women worldwide, and therefore, improved approaches for its early detection are urgently needed. As microRNAs (miRNAs) are increasingly recognized as critical regulators in tumorigenesis and possess excellent stability in plasma, this study focused on using miRNAs to develop a method for identifying noninvasive biomarkers. Methods: To discover critical candidates, differential expression analysis was performed on tissue-originated miRNA profiles of 409 early breast cancer patients and 87 healthy controls from The Cancer Genome Atlas database. We selected candidates from the differentially expressed miRNAs and then evaluated every possible molecular signature formed by the candidates. The best signature was validated in independent serum samples from 113 early breast cancer patients and 47 healthy controls using reverse transcription quantitative real-time polymerase chain reaction. Results: The miRNA candidates in our method were revealed to be associated with breast cancer according to previous studies and showed potential as useful biomarkers. When validated in independent serum samples, the area under curve of the final miRNA signature (miR-21-3p, miR-21-5p, and miR-99a-5p) was 0.895. Diagnostic sensitivity and specificity were 97.9% and 73.5%, respectively. Conclusion: The present study established a novel and effective method to identify biomarkers for early breast cancer. And the method, is also suitable for other cancer types. Furthermore, a combination of three miRNAs was identified as a prospective biomarker for breast cancer early detection.

임신 중 체중변화와 임부 및 신생아 상태에 관한 연구 (The studies about the weight-changes during pregnancy and the condition of mother and infant)

  • 박광희
    • 부모자녀건강학회지
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    • 제4권1호
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    • pp.68-81
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    • 2001
  • This research is to study about the weight-change of a pregnant woman, conditions of the woman and an infant. The weight-change of a mother during pregnancy was observed and that was expressed as the basis on the body mass index of a mother before pregnancy. The effects of weight-changes on both the discomfort, complications of pregnant mother and the condition of an infant were also investigated. Thus we set a purpose that this study would help pregnant woman and an infant to maintain and enhance their health conditions by proper weight control through nursing mediation. This study was performed in a certain hospital of university in seoul from Feb. 1. 2000 to Mar. 31. 2000. We explained the purpose of this study to the hospital institution and obtained consent of investigation. 152 inpatients who were in condition from PA 37 weeks to PA 42 weeks were the subject of this study. The research materials were made through of question paper that inpatients make answer by themselves and investigation paper. The question paper was about general background, weight and height before pregnancy and discomfort of the physical degree. And the investigation paper was about parity, maternal weight(late pregnancy), high pregnancy, delivery method, hemoglobin level, Apgar score, fetal weight. Physical discomfort was measured using the implement made by Kim hae won(1996) (chronbach's ${\alpha}=0.85$). SPSS was used to do statistics for managing and analyzing data. The results of this study were like followings. 1. The mean value of gained weight during pregnancy was about 13.8kg within from 3 kg to 26 kg. Among 152 research candidates, the gained weight of 80(52.6%) candidates remained within an ideal range. But that of 37 candidates(24.3%) became less than the ideal range. Also that of 35 candidates(23.0%) became over than the ideal range. 2. In the investigation of the relation between the weight change of a pregnant woman and her condition, the scores to represent physical discomfort were middle in all candidates. And the physical discomfort of over weight-gained group was more than that of low weight-gained group, but there was no difference in statistics(F=0.234, p=0.791). The weight-changes of pregnant woman didn't have an influence with the high risk of pregnancy(F=0.509, p=0.477). Also, the weight-changes didn't have an influence on delivery method($x^2=3.825$, p=0.148). However, in the investigation of the relation between weight-change and hemoglobin level, the change of hemoglobin level was highest in over weight gained group(F=3.062, p=0.05). 3. In the investigation of the weight-change of pregnant woman and the condition of infant. the weight changes didn't have an influence on both 1 min Apgar score(F=0.157, p=0.855) and 5 min Apgar score(F=0.030, p=0.970) of infant. Also, in the investigation of weight-change of a pregnant woman and weight difference of a infant with Pearson Correlation Coefficient, the weight-change of a pregnant woman affected vastly the weight of a infant. It was also found that the more pregnant woman gained in weight, the more did gain weighty infants. This relation was in net proportion(r=0.256, p=0.001). In conclusion, these results suggest that the weight-changes during pregnancy in Korea women of these days are more increased than that of the past days and individual variation in weight-changes is very high. Also, these results suggest that the changed hemoglobin level of a mother and weight of an infant were meaningfully affected by the weight-changes of a pregnant woman during pregnancy. However, the physical discomfort of a pregnant woman, the high risks of pregnancy, the delivery method and Apgar score of an infant were not affected by the weight-changes during pregnancy. Because the recommendation suggesting the ideal weight-change, used this study, is basis on the subject of American women, therefore, these results also suggest the necessity of such recommendation which is subject to Korean women.

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Revisiting 'It'-Extraposition in English: An Extended Optimality-Theoretic Analysis

  • Khym, Han-gyoo
    • International Journal of Advanced Culture Technology
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    • 제7권2호
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    • pp.168-178
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    • 2019
  • In this paper I discuss a more complicated case of 'It'-Extraposition in English in the Optimality Theory [1] by further modifying and extending the analysis done in Khym (2018) [2] in which only the 'relatively' simple cases of 'It'-Extraposition such as 'CP-Predicate' was dealt with. I show in this paper that the constraints and the constraint hierarchy developed to explain the 'relatively' simple cases of 'It'-Extraposition are no longer valid for the more complicated cases of 'It'-Extraposition in configuration of 'CP-V-CP'. In doing so, I also discuss two important theoretic possibilities and suggest a new view to look at the 'It'-Extraposition: first, the long-bothering question of which syntactic approach between P&P (Chomsky 1985) [3] and MP (Chomsky 1992) [4] should be based on in projecting the full surface forms of candidates may boil down to just a simple issue of an intrinsic property of the Gen(erator). Second, the so-called 'It'- Extraposition phenomenon may not actually be a derived construction by the optional application of Extraposition operation. Rather, it could be just a representational construction produced by the simple application of 'It'-insertion after the structure projection with 'that-clause' at the post-verbal position. This observation may lead to elimination of one of the promising candidates of '$It_i{\ldots}[_{CP}that{\sim}]_i$' out of the computation table in Khym [2], and eventually to excluding the long-named 'It'-Extraposition case from Extrsposition phenomena itself. The final constraints and the constraint hierarchy that are explored are as follows: ${\bullet}$ Constraints: $^*SSF$, AHSubj, Subj., Min-D ${\bullet}$ Constraint Hierarchy: SSF<<>>Subj.>> AHSubj.

Electrochemistry of Conductive Polymers 46. Polymer Films as Overcharge Inhibitors for Lithium-Ion Rechargeable Batteries

  • Choi, Shin-Jung;Park, Su-Moon
    • Journal of Electrochemical Science and Technology
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    • 제1권1호
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    • pp.1-9
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    • 2010
  • Conducting polymer films grown from various aromatic compounds have been evaluated as overcharge protecting additives for lithium ion rechargeable batteries. The polymer films were grown electrochemically under the conditions similar to those encountered during the overcharging processes of lithium batteries and subsequently characterized by potentiodynamic, electrochemical quartz crystal microbalance, electrochemical impedance spectroscopic, and scanning electron microscopic experiments. Results indicate that bicyclic and polycyclic aromatic hydrocarbons would be poor candidates for inhibitors, while biphenyl, terphenyl, and benzene derivatives displayed excellent performances. Mixed polymer films grown from o-terphenyl and p-xylene show the best performance among the candidates.

보호기기 동작시 전류파형과 탈락부하량을 고려한 방사상 배전계통 고장점 추정방법 (A New Diagnosis of Actual Fault Location in Distribution Power Systems by Comparing the Current Waveform and the Amount of Interrupted Load)

  • 최면송;이승재;이덕수;진보건;현승호
    • 대한전기학회논문지:전력기술부문A
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    • 제52권2호
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    • pp.99-106
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    • 2003
  • In this paper, an intelligent fault location and diagnosis system is proposed. The proposed system identifies the fault location in two-step procedure. The first step identifies candidates of fault location using an fault distance calculation using an iterative method. The second step is diagnosis the actual fault location in the candidates by comparing the current waveform patterns with the expected operation of the protective devices and considering the interrupted load after the operation protective device. The simulations results in the case study demonstrates a good performance of the proposed fault location and diagnosis system.

New Alternative Splicing Isoform and Identification of the Kinase Activity of N-Terminal Kinase-Like Protein (NTKL)

  • Merlin, Jayalal L.P.
    • 통합자연과학논문집
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    • 제6권4호
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    • pp.234-243
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    • 2013
  • N-terminal kinase-like (NTKL) protein was initially identified as a protein binding to protein kinase B (PKB, also known as Akt). Though NTKL-BP1 (NTKL-binding protein 1) has been identified as an NTKL binding protein, its functions related to binding have not yet been elucidated. Here, a new alternative spliced variant of NTKL and its association with integrin ${\beta}1$ is described, in addition to the kinase activity of NTKL and its substrate candidates. Although the phosphorylation of the candidates must be further confirmed using other experimental methods, the observation that NTKL can phosphorylate ROCK1, DYRK3, and MST1 indicates that NTKL may act as a signaling protein to regulate actin assembly, cell migration, cell growth, and to facilitate differentiation and development in an integrin-associated manner.

The effect of the dexamethasone, cytarabine, and cisplatin (DHAP) regimen on stem cell mobilization and transplant outcomes of patients with non-Hodgkin's lymphoma who are candidates for up-front autologous stem cell transplantation

  • Jeon, So Yeon;Yhim, Ho-Young;Kim, Hee Sun;Kim, Jeong-A;Yang, Deok-Hwan;Kwak, Jae-Yong
    • The Korean journal of internal medicine
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    • 제33권6호
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    • pp.1169-1181
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    • 2018
  • Background/Aims: Data on dexamethasone, cytarabine, and cisplatin (DHAP) as a mobilization regimen, compared to high-dose cyclophosphamide (HDC), for up-front autologous stem cell transplantation (ASCT) in non-Hodgkin's lymphoma (NHL) is limited. Methods: Consecutive patients with aggressive NHL treated with cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) or rituximab-CHOP who underwent chemomobilization using HDC or DHAP plus granulocyte-colony stimulating factor (G-CSF) for up-front ASCT were enrolled from three institutions between 2004 and 2014. Results: Ninety-six patients (57 men) were included. Sixty-five patients (67.7%) received HDC; and 31 (32.3%), DHAP. The total CD34+ cells mobilized were significantly higher in patients receiving DHAP (16.1 vs. $6.1{\times}10^6/kg$, p = 0.001). More patients achieved successful mobilization with DHAP (CD34+ cells ${\geq}5.0{\times}10^6/kg$) compared to HDC (87.1% vs. 61.5%, respectively; p = 0.011), particularly within the first two sessions of apheresis (64.5% vs. 32.3%, respectively; p = 0.003). Mobilization failure rate (CD34+ cells < $2.0{\times}10^6/kg$) was significantly higher in patients receiving HDC (20.0% vs. 3.2%, p = 0.032). On multivariate analysis, the DHAP regimen (odds ratio, 4.12; 95% confidence interval, 1.12 to 15.17) was an independent predictor of successful mobilization. During chemomobilization, patients receiving HDC experienced more episodes of febrile neutropenia compared to patients receiving DHAP (32.3% vs. 12.9%, p = 0.043). Conclusions: The DHAP regimen was associated with a significantly higher efficacy for stem cell mobilization and lower frequency of febrile neutropenia. Therefore, DHAP plus G-CSF is an effective for mobilization in patients with aggressive NHL who were candidates for up-front ASCT.

Immunization effect of recombinant P27/30 protein expressed in Escherichia coli against the hard tick Haemaphysalis longicornis (Acari: Ixodidae) in rabbits

  • You, Myung-Jo
    • Parasites, Hosts and Diseases
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    • 제42권4호
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    • pp.195-200
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    • 2004
  • We investigated the induction of resistance to Haemaphysalis longicornis infestation in rabbits that had been immunized with recombinant H. longicornis P27/30 protein. The success of immunological control methods is dependent upon the use of potential key antigens as tick vaccine candidates. Previously, we cloned a gene encoding 27 kDa and 30 kDa proteins (P27/30) of H. longicornis, and identified P27/30 as a troponin I-like protein. In this study, rabbits that were immunized with recombinant P27/30 expressed in Escherichia coli showed the statistically significant longer feeding duration for larval and adult ticks (P<0.05), low engorgement rates in larval ticks (64.4%), and an apparent reduction in egg weights, which suggest that H. longicornis P27/30 protein is a potential candidate antigen for a tick vaccine. These results demonstrated that the recombinant P27/30 protein might be a useful vaccine candidate antigen for biological control of H. longicornis.