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Toxic Effect of S-Bioallethrin in Rats (Rat에 있어서 S-bioallethrin 독성에 관한 연구)

  • 홍사욱;김형식;정규혁
    • Environmental Analysis Health and Toxicology
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    • v.7 no.1_2
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    • pp.17-34
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    • 1992
  • The object of this study is to investigate the toxicity of S-biol (d-allethron-d-transchrysanthemate) and the mode of action between other synthetic pyrethroid insecticides and S-biol in rats. Rats were treated daily with S-biol (25 mg/kg, 50 mg/kg, 100mg/kg) by oral administration for 5 weeks. The experimental results were summerized as follows: Biochemical parameters such as LDH and Glucose in serum were much more increased in control groups. No significant hematological change excepts for MCHC in rats treated with S-biol 100 mg/kg were observed in all groups compared to control groups. In animals treated with S-biol for 4∼5 weeks, the levels of cytochrome P-450 in the liver were significantly increased. In renal microsomal fractions, however, no significant changes of cytochrome P-450 contents were observed. The activitis of ATPase in groups treated with S-biol (50 mg/kg, 100 mg/kg) were decreased compared to those in other groups. TBA values and activities of glucose-6-phosphatase in the liver were increased a little in the groups treated with S-biol (100 mg/kg) for 5 weeks. The activities of cholinesterase in hepatic and serum were not significantly changed in all groups but slightly decreased in animals treated with high dose of S-biol (100 mg/kg). The activities of carboxylesterase in serum and in the liver were slightly increased but not significantly changed.

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A Basic Study on the Variation of Temperature Characteristics for Attenuation Coefficient and Sound Velocity in Biological Tissues

  • Park, Heung-Ho
    • Journal of Biomedical Engineering Research
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    • v.14 no.3
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    • pp.273-282
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    • 1993
  • This study is concerned with the temperature dependence characteristics of ultrasound parameters in biological tissues, which are basic on the noninvasive deep body temperature estimation. Used parameters are ultrasonic attenuation coefficient and sound velocity In order to accomplishment our purpose, several signal processing methods were used. Attenua4iorl coefficient was estimated by spectral difference method and sound velocity was estimated by P-P method. And we also examined these methods through a series of IN VITRO experi mentis that used tissue-mimicking phantom samples and biological tissue samples. In order to imitate the biological soft tissue two kinds of phantom samples are used, one is agar phantom sample which is composed of agar, graphite, N-propyl alcohol and distilled water, and the other is fat phantom sample which is composed of pure animal fat. And the ultrasound transmission mode and reflection mode experiments are performed on the pig's spleen, kidney and fat. As a result, it is found that the temperature characteristics are uniform in case of phan- tom samples but not in biological tissues because of complicate wave propagation within them. Consequently, the possibility of temperature measurement using ultrasound on biological tissue is confirmed and its results may contribute to the establishment of reference values of internal temperature measurement of biological tissues.

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A 16-channel CMOS Inverter Transimpedance Amplifier Array for 3-D Image Processing of Unmanned Vehicles (무인차량용 3차원 영상처리를 위한 16-채널 CMOS 인버터 트랜스임피던스 증폭기 어레이)

  • Park, Sung Min
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.64 no.12
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    • pp.1730-1736
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    • 2015
  • This paper presents a 16-channel transimpedance amplifier (TIA) array implemented in a standard $0.18-{\mu}m$ CMOS technology for the applications of panoramic scan LADAR (PSL) systems. Since this array is the front-end circuits of the PSL systems to recover three dimensional image for unmanned vehicles, low-noise and high-gain characteristics are necessary. Thus, we propose a voltage-mode inverter TIA (I-TIA) array in this paper, of which measured results demonstrate that each channel of the array achieves $82-dB{\Omega}$ transimpedance gain, 565-MHz bandwidth for 0.5-pF photodiode capacitance, 6.7-pA/sqrt(Hz) noise current spectral density, and 33.8-mW power dissipation from a single 1.8-V supply. The measured eye-diagrams of the array confirm wide and clear eye-openings up to 1.3-Gb/s operations. Also, the optical pulse measurements estimate that the proposed 16-channel TIA array chip can detect signals within 20 meters away from the laser source. The whole chip occupies the area of $5.0{\times}1.1mm^2$ including I/O pads. For comparison, a current-mode 16-channel TIA array is also realized in the same $0.18-{\mu}m$ CMOS technology, which exploits regulated-cascode (RGC) input configuration. Measurements reveal that the I-TIA array achieves superior performance in optical pulse measurements.

Frequency Window Method for the Vibration of Secondary Structural Systems (Frequency Window Method에 의한 Secondary 구조 시스템의 진동특성)

  • ;Igusa, Takeru;Achenbach, Jan D.
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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    • 1991.04a
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    • pp.153-158
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    • 1991
  • Recently, demands on light weight, high strength, and low noise or vibration have led to the design of complicated structural systems. Although finite elements [1], mode synthesis [2], and statistical energy analysis [3] can be used to compute the dynamic response of such systems, the structural complexity has made the interpretation of the results of such analysis difficult. Many researchers in dynamic analysis have sought to further develop existing theories or develop alternate methods to obtain greater insight in the behavior of large massive primary systems (P systems) with connected light secondary systems (S systems). Some recent research includes work by Sackman and Kelly [4], Sackman et al.[5], Der Kiureghian et al.[6], and Igusa and Der Kiureghian [7-9] who have combined mode synthesis concepts, matrix algebraic theory, and perturbation methods for characterizing weakly-coupled structural systems. A major limitation of these works are that they are limited to lumped mass S systems. In this paper, the general ideas in the Refs.[4-9] are used to study continuous S systems and the method to reduce the complexity, studied in the works by Igusa, Achenbach, and Min [10,11], is developed into the frequency window method.

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NUMERICAL ANALYSIS FOR TURBULENT FLOW AND AERO-ACOUSTIC OVER A THREE DIMENSIONAL CAVITY WITH LARGE ASPECT RATIO (3차원 고세장비 공동 주위의 난류유동 및 음향 특성에 관한 수치적 연구)

  • Mun, P.U.;Kim, J.S.
    • 한국전산유체공학회:학술대회논문집
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    • 2008.03a
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    • pp.297-301
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    • 2008
  • The flight vehicles have cavities such as wheel wells and bomb bays. The flow around a cavity is characterized as unsteady flow because of the formation and dissipation of vortices due to the interaction between the freestream shear layer and cavity internal flow, the generation of shock and expansion waves. Resonance phenomena can damage the structures around the cavity and negatively affect aerodynamic performance and stability. The flow field is observed to oscillate in the "shear layer mode" with low aspect ratio. In the present study, numerical analysis was performed for cavity flows by the unsteady compressible three dimensional Reynolds-Averaged Navier-Stokes (RANS) equations with Wilcox's $\kappa$-$\omega$ turbulence model. The flow field is observed to oscillate in the shear layer mode" with large aspect ratio. Based on the SPL(Sound Pressure Level) analysis of the pressure variation at the cavity trailing edge, the dominant frequency was analyzed and compared with the results of Rossiter's formul. The aero-acoustic wave analyzed with CPD(Correlation of Pressure Distribution).

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NUMERICAL ANALYSIS FOR TURBULENT FLOW AND AERO-ACOUSTIC OVER A THREE DIMENSIONAL CAVITY WITH LARGE ASPECT RATIO (3차원 고세장비 공동 주위의 난류유동 및 음향 특성에 관한 수치적 연구)

  • Mun, P.U.;Kim, J.S.
    • 한국전산유체공학회:학술대회논문집
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    • 2008.10a
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    • pp.297-301
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    • 2008
  • The flight vehicles have cavities such as wheel wells and bomb bays. The flow around a cavity is characterized as unsteady flow because of the formation and dissipation of vortices due to the interaction between the freestream shear layer and cavity internal flow, the generation of shock and expansion waves. Resonance phenomena can damage the structures around the cavity and negatively affect aerodynamic performance and stability. The flow field is observed to oscillate in the "shear layer mode" with low aspect ratio. In the present study, numerical analysis was performed for cavity flows by the unsteady compressible three dimensional Reynolds-Averaged Navier-Stokes (RANS) equations with Wilcox's ${\kappa}-{\varepsilon}$ turbulence model. The flow field is observed to oscillate in the "shear layer mode" with large aspect ratio. Based on the SPL(Sound Pressure Level) analysis of the pressure variation at the cavity trailing edge, the dominant frequency was analyzed and compared with the results of Rossiter's formul. The aero-acoustic wave analyzed with CPD(Correlation of Pressure Distribution).

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The 1.6[kW] Class Single Phase ZCS-PWM High Power Factor Boost Rectifier (1.6[kW]급 단상 ZCS-PWM HPF 승압형 정류기)

  • Mun, S.P.;Kim, S.I.;Yun, Y.T.;Kim, Y.M.;Lee, H.W.;Suh, K.Y.
    • Proceedings of the KIEE Conference
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    • 2003.07b
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    • pp.1169-1171
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    • 2003
  • This paper presents a 1.6[kW]class single phase high power factor(HPF) pulse width modulation(PWM) boost rectifier featuring soft commutation of the active switches at zero current. It incorporates the most desirable properties of conventional PWM and soft switching resonant techniques. The input current shaping is achieved with average current mode control and continuous inductor current mode. This new PWM converter provides zero current turn on and turn off of the active switches, and it is suitable for high power applications employing insulated gate bipolar transistors(IGBT'S). The principle of operation, the theoretical analysis, a design example, and experimental results from laboratory prototype rated at 1.6[kW] with 400[Vdc] output voltage are presented. The measured efficiency and the power factor were 96.2[%] and 0.99[%], respectively, with an input current Total Harmonic Distortion(THD) equal to 3.94[%], for an input voltage with THD equal to 3.8[%], at rated load.

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The Study on the Properties of He Glow discharge in a Dielectric Barrier Discharge (DBD) Model (DBD 전극구조에서의 He 가스 글로우방전 특성연구)

  • So, Soon-Youl
    • The Transactions of the Korean Institute of Electrical Engineers P
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    • v.67 no.4
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    • pp.214-220
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    • 2018
  • Light sources induced by gas discharge using rare gases have been widely used in the thin film deposition, the surface modification and the polymer etching. A dielectric barrier discharge (DBD) has been developed in order to consistently emit light and control the wavelength of the emission light. However, much research on the characteristics of the movement of discharge particles is required to improve the efficiency of the light lamp and the life-time of the light apparatus in detail. In this paper, we developed a He DBD discharge simulation tool and investigated the characteristics of discharge particles which were electrons, two positive ions ($He^+$, $He_2^+$) and 5 excited particles ($He^*(1S)$, $He^*(3S)$, $He^*$, $He^{**}$, $He^{***}$). The discharge currents showed the transition from pulse mode to continuous mode with the increase of power. With the accumulated charges on the barrier walls, the discharge current was rapidly increased and caused oscillation of the discharge voltage. As the gas pressure increased, $He_2^+$ and $He^*(3S)$ became the dominant activated particles. The input power was mostly consumed by electrons and $He_2^+$ ion. And the change curve showed that power consumption by electrons increased more with gas pressure than with source voltage or frequency.

The Study on Usefulness of LEAP Collimator in Lung Ventilation SPECT (Lung Ventilation SPECT에서 LEAP Collimator의 유용성에 관한 연구)

  • Kim, Jung Soo;Kim, Soo Mee;Kim, Jin Eui;Lee, Jae Sung;Lee, Dong Soo
    • The Korean Journal of Nuclear Medicine Technology
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    • v.16 no.2
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    • pp.18-24
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    • 2012
  • Purpose : Although lung ventilation SPECT (LV-SPECT) has a good sensitivity in detection of deep lung lesions, it is difficult to apply the LV-SPECT to patients having breathing problems due to limited examination time. In this study, we evaluated the usefulness of LEAP collimator, which provides high detection sensitivity and tolerable resolution, for the LV-SPECT in terms of diagnostic accuracy and examination time. Materials and Methods : Four volunteers inhaled Technegas (370 MBq) and the lung ventilation planar scan (LVPS, 300 counts/view (cpv)) with LEHR collimator was performed using Siemens E.cam scanner as a reference test. LV-SPECT scans were performed with three collimators, LEHR, LEUHR, and LEAP, in low (7 kcpv) and high (70 kcpv) counting modes. The count ratios of left (LT) and right (RT) lung segments were calculated on the geometric mean view of anterior and posterior images for LVPS and on the summed coronal images of LV-SPECT, respectively. Comparing to LVPS, the usefulness of three different collimators for LV-SPECT was evaluated through statistical analysis (paired t-test), on count ratios of lung segments. Results : The average LT:RT ratio in LVPS was 47:53. For LV-SPECT, there were negligible difference of the LT:RT ratios (48:52 on average) among three different collimators in low and high counting modes. Comparing to standard LVPS with LEHR, all LV-SPECTs with different collimators resulted in similar diagnostic accuracy through paired t-test (p>0.05). The scan time in LVPS (6 views) was 17.3 min. For LV-SPECT (128 views) in low counting mode, it took 18.7 (LEUHR), 15.0 (LEHR), and 12.3 min (LEAP), respectively. Conclusion : Comparing to standard LVPS, the LV-SPECT with LEAP in low counting mode provided the comparable diagnostic accuracy in addition to shortened scan time.

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Packet Delay Budget Aware AMC Selection for 3G LTE of Evolved Packet System (Evolved Packet System의 3G LTE에서 패킷별 지연허용시간을 고려한 AMC 선택 기법)

  • Jun, Kyung-Koo
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.33 no.8A
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    • pp.787-793
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    • 2008
  • 3GPP evolved packet system (EPS) is an all-IP based system that supports various access networks such LTE, HSPA/HSPA+, and non-3GPP networks. Recently, the support of IP flows with packet level QoS profiles was added to the requirements of the EPS. This paper proposes an adaptive modulation and coding (AMC) scheme that supports the QoS of such IP flows in the 3G LTE access network of the EPS. Defining the retransmission as a critical factor for QoS, the proposed scheme applies different maximum packet error probability $P_{max}$ to each packet when selecting the AMC transmission mode. In determining $P_{max}$, the QoS constraints and NACK-to-ACK error as well as channel condition are considered, balancing two objectives: the satisfaction of the QoS and the maximization of spectral efficiency. The simulation results show that it is able to reduce both delay violation and status report by 10%, while improving the throughput 10% in comparison with an existing scheme.