• Journal of the Korea Academia-Industrial cooperation Society
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• v.16 no.1
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• pp.498-506
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• 2015

This paper investigates the association of among alcohol consumption and blood vitamin D and lead concentrations. Subjects to 4,074 with adults over the age of 20 in the 5th Korea National Health and Nutrition Examination Survey, correlation analysis is used to validate the relations between an average daily alcohol consumption and blood vitamin D and lead concentration, and to study the effects of blood vitamin D to the lead concentration is carried out regression analysis. The correlation analysis shows that alcohol consumption has the correlation with blood vitamin D and lead concentration(p<0.01). As the results of regression analysis, age(p<0.01), education(p<0.01), occupation(p<0.05), alcohol consumption(p<0.01), vitamin D(p<0.05) appear significant influence on lead concentration in male. Alcohol consumption increases not only lead concentration but also vitamin D. Blood vitamin D also contributes to the rise in lead concentration, but in the reverse the metabolic activity of blood vitamin D by influence of lead receives a negative effect in our body.

• Korean Journal of English Language and Linguistics
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• v.3 no.3
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• pp.427-452
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• 2003

Korean is famous for having all voiceless stop sounds. Korean does have voiced stops but they are considered to exist only as the allophones of word initial /p, t, k/. My experiment shows the English word initial stop sounds [b, d, g] and the Korean lax stop series /p, t, k/ in word initial position are similar in the range of voice onset time. If English word initial[b, d, g] sounds are posited as voiced, then Korean word initial /p, t, k/ should be classified as voiced also. Phonetically English /b, d, g/ phonemes and Korean /p, t, k/ phonemes are very similar except the word initial [p, t, k] are devoiced slightly more, but not significant enough to be classified as voiceless than English word initial [b, d, g]. If we posit /b, d, g/ as Korean phonemes, it explains why Korean /p, t, k/ series has the allophones [b, d, g] instead of fortis stops /p', t', k'/ in Korean even though /p', t', k'/ has less positive VOT value than /p, t, k/. If we posit /b, d, g/ as Korean phonemes, then it does not cause spelling or pronunciation confusion either when Koreans learn English or English speakers learn Korean.

• The Korean Journal of Zoology
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• v.6 no.2
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• pp.11-15
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• 1963

A total of 220 adult male mice (18-20g) of the S.M. strain were divided into ten experimental and control groups. The total-body X-ray irradiation doses used were 50 r, 100r, 200r, 400r, 600r, 800r, 1,000r, 1,200r, 1,400r, and1,600r. The respiratory arrest (mortality) caused by each irradiation doses were observed for 30 days. Relationships between irradiation doses and survival time and percentage of response were examined. From this experiment, a formula was obtained to express the relationship among three factors, which may be presented as follows : {{{{{{{{P= { 10} over { SQRT { 2 pi } } INT _{ - INF }^{ p'} e-{(p'-50)^2 } over {200 }dp···(a) p'=100 LEFT { t^0.3- LEFT ( { { 16.9965} over {D-60 } } RIGHT ) ^{ { 1} over {2.5 } } } / LEFT { LEFT ( { 26372.43} over {D-81.86 } RIGHT ) ^{ { 1} over {2.5 } } -( { { 16.9965} over {D-60 } } RIGHT ) ^{ { 1} over {2.5 } } ···(b) p= { (D-60) t^0.75-16.9965} over {0.2186 t^0.75 +263.55434 }····(c) }} {{{{P= { 10} over { SQRT { 2 pi } } INT _{ - INF }^{ p'} e-{(p'-50)^2 } over {200 }dp···(a) p'=100 LEFT { t^0.3- LEFT ( { { 16.9965} over {D-60 } } RIGHT ) ^{ { 1} over {2.5 } } } / LEFT { LEFT ( { 26372.43} over {D-81.86 } RIGHT ) ^{ { 1} over {2.5 } } -( { { 16.9965} over {D-60 } } RIGHT ) ^{ { 1} over {2.5 } } ···(b) p= { (D-60) t^0.75-16.9965} over {0.2186 t^0.75 +263.55434 }····(c)

• The Korean Journal of Ecology
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• v.23 no.4
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• pp.315-321
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• 2000

The occurrence and distribution of Dictyostelid cellular slime molds on Mt. Mukak soils with two different vegetation types were investigated. Two plating methods were used for the isolation of dictyostelids following Dr. Hagiwara's method. Dictyostelium and Polysphondylium were isolated in these soils. D. purpureum (subtropical form ) and D. giganteum were observed in both Quercus variabilis and Pinus thunbergii communities soils. D. delicatum, B. sp-1 (D. brefeldianum complex). D. sp-2 (D. brefeldianum complex), D. minutum and P. pallidum complex occurred only in Q. variabilis soil. D. macrocephalum, D. purpureum (temperate form ), D. robustum, D. polycephalum, P. violaceum, and P. pallidium occurred only in P. thunbergii soil. P. pallidium complex is being identified.

• Journal of Korean Society of Transportation
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• v.15 no.1
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• pp.45-62
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• 1997

이 논문은 O-D 접근방법과 P-A 접근방법을 이론적으로 서로 비교한 연구이다. O-D 접근방법은 전통적인 교통수요 4단계 분석기법의 모든 과정에서 통행수 산출을 통행 유출과 통행유인의 개념을 적용하여 O-D 통행량을 사용한 기법으로 정의되었다. 이러한 O-D 접근방법은 우리 나라에서 보편적으로 사용되고 있는 기법이다. P-A 접근방법은 통행 발생, 통행분포, 교통수단선책 분석과정까지 통행생성과 통행유인의 개념을 적용하여 P-A 통행량을 사용한 기법으로 정의되었으며, 노선배경 분석단계에 앞서 P-A 통행량을 O-D 통 행량으로 전환되어져야 한다. P-A 접근방법은 구미국가들에서 보편적으로 사용되는 기법이 다. 이러한 두 접근방법은 통행목적 분류에서 귀가통행이 별도로 분류되어있는가 혹은 아닌 가에 따라 쉽게 구분되어 질 수 있다. 만일 귀가통행이 통행목적의 분류에서 별도로 구분되 어 있으면 O-D 접근방법이 적용되고 있음을 의미하는 것이다. 이 연구는 전통적 교통수요 4단계 분석과정 중 통행발생, 통행분포 및 교통수단선택의 각 분석과정에서 두 접근방법간 의 이론적 차이점을 명확히 비교 분석하고자 하였다. 그러므로써 형태적 통행패턴을 상대적 으로 잘 설명하며 또한 집합적 오차를 상대적으로 초 lth화할 수 있는 기법이 어느 것인가 를 이론적으로 찾고자 하였다. 이 연구에서는 행태적 측면에서 통행패턴을 P-A 접근방법이 더 잘 표현하고 있으며 또한 집합화 오차도 P-A 접근방법이 더 적으므로 P-A 접근방법이 O-D 접근방법보다 이론적으로 더 우수하다고 결론지었다. 또한 이 연구는 통행발생, 통행 분포, 교통수단선택 분석과정이 끝난 후 P-A 통행량에서 O-D 통행량으로 전환하는 것이 통행발생, 통행분포의 분석과정이 끝난 후에 O-D 통행량으로 전환하는 것보다 더 바람직하 다고 추천하였다.

• Journal of Chest Surgery
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• v.31 no.12
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• pp.1200-1205
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• 1998

Background: Lung cancer formation is a multistage process involving activation of protooncogene and inactivation of tumor suppressor genes. We evaluate the significance of cyclin D1, p53, bcl-2 gene mutations in patients with curatively resected stage IIIA non-small cell lung cancer(NSCLC). Material and Method: One hundred consecutive cases of stage IIIA lung cancers from patients operated on curatvely between 1990 and 1995 for which adequate paraffin blocks and clinical history were available. Immunohistochemical studies were performed on the representative tissue sections from each case by the labelled streptovidin- biotin method. Sections for cyclin D1, p53, Bcl-2 immunostaining were pretreated in a microwave oven for 10 to 20 minutes in citrate buffer before immunostaining. The overnight incubation with NCL-cyclin D1-GM for cyclin D1, with clone DO-7 for p53, with clone 124 for bcl-2 was done. Mean follow-up was 24.1 months (range 2-84 months) after operation. Result: One hundred cases of lung cancers were composed of 56 cases of squamous cell carcinoma, 37 cases of adenocarcinoma, 5 cases of adenosquamous cell carcinoma, and 2 cases of large cell carcinoma. The 5-year survival was 32.1%. The positive expression rate of cyclin D1 was 35%, p53 was 56%, and bcl-2 was 17%. But there were no correlation between cyclin D1, p53, Bcl-2 protein expression and survival. Conclusion: These observation indicate that cyclin D1, p53, bcl-2 protein overexpression might be implicated in the oncogenesis of non-small cell lung carcinomas but they have no usefulness as a prognostic marker.

• Journal of Navigation and Port Research
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• v.32 no.4
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• pp.271-277
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• 2008

When performing steering by an autopilot (automatic steering gear), a sensitivity adjustment is mainly determined by P value and D value. These values differ in the optimal combination by model of ship and external forces. This research was carried out simulation case studies and examined movement of Pure Car Carrier, which easily received ship by wind pressure influence in low speed We investigated the relation of horizontal migration(transfer) of ship's body and P-D value. Based on it, four parameters of P-D at approaching berth could be suggested Hence there were suggestions of parameters; Distance to maximum lee point, Time to maximum lee point, Time to return to original course and Time to 300th second. The correlation of these parameters and P-D value were also considered. As a result, we think that this index, like formulated P-D, leads to an easy and safe navigation by utilizing these indices.

• Food Engineering Progress
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• v.21 no.2
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• pp.103-109
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• 2017

Alginate lyase from Streptomyces violaceoruber was purified by DEAE sephacel chromatography and SP sepharose chromatography. The specific activity of the purified enzyme was 14.6 units/mg protein, representing a 40.6-fold purification of the crude extract. The final preparation thus obtained showed a single band on Tricine-SDS polyacrylamide gel electrophoresis whose molecular weight was determined to be 23.3 kDa. The polyMG block of sodium alginate was hydrolyzed by the purified alginate lyase and then separated by activated carbon column chromatography and bio gel P-2 gel filtration. The main hydrolysates were composed of hetero type M/G-oligosaccharides with the degrees of polymerization (D.P.) being 6 and 8. To investigate the effects of hetero type M/G-oligosaccharides from the sodium alginate on the growth of some intestinal bacteria, cells were cultivated individually on the modified-MRS medium containing D.P. 6 and 8 M/G-oligosaccharides. B. longumgrew 4.25-fold and 6.44-fold more effectively by the treatment of D.P. 6 and 8 M/G-oligosaccharides compared with those of standard MRS medium. In addition, B. bifidumgrew 3.3-fold and 5.4-fold more effectively by the treatment of D.P. 6 and 8 M/G-oligosaccharides. In conclusion, D.P. 8 was more effective than D.P. 6 hetero M/G-oligosaccharides as regards the growth of Bifidobacteriumspp. and Lactobacillus spp.

• Journal of the Korean Society of Food Science and Nutrition
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• v.33 no.1
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• pp.107-113
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• 2004

This study explored the association between the bone nutrition indicators and the bone mineral density (BMD) in 138 apparently healthy elderly (male: 38, female: 100) dwelling in a low income area of the city. Dietary intakes were estimated from two meals (breakfast ＆ dinner) and snack using 24 hr-recall method and lunch with weighing over 3 consecutive days. Female elderly showed significant lower intakes (p<0.001∼p<0-05) for most of the nutrients except calcium and vitamin C than the elderly male. Calcium and vitamin D intakes for both male and female were 331.0 mg, 1.89 $\mu\textrm{g}$ and 308.6 mg, 1.21 $\mu\textrm{g}$, respectively and they were below the 50% of the RDA. Both the BMDs at lumbar spine (LS) and femoral neck (FN) were positively correlated with the energy intake, calcium intake and vitamin D intake (p<0.05, respectively) for male. In female BMDs of the both sites were positively correlated with the intakes of carbohydrates, protein, lipid, calcium and vitamin D (p<0.01∼p<0.05). Female showed higher serum osteocalcin (p<0.01) and urinary deoxypyridinoline/creatinine (DPYR/CR) (p<0.001), meaning that female had elevated rate in bone turn over and bone resorption. The proportion of subjects with vitamin D deficiency assessed with serum 25(OH)VitD$_3$<10 mg/mL was 35.0% for female and 23.7% for male, respectively Both the BMDs at lumbar spine and trochanter were positively correlated with serum 25(OH)VitD$_3$ but BMDs in most of the sites were negatively associated with urinary DPYR/CR, phosphate/CR. Stepwise multiple regression showed physical activity, serum alkaline phosphatase, weight, vitamin D explained 47.6% of the variation of the LS BMD. The indicator variable for serum alkaline phosphatase was negatively associated with LS BMD. However, the indicator variable for weight and vitamin D intake were positive and significant (p=0.0087, p=0.0007, respectively). For FN BMD, the indicator variable for age and serum alkaline phosphatase were negative and significant (p<0.0075, p<0.0015, respectively) and the weight was positively associated with the FN BMD.

• Korean Journal of Microbiology
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• v.50 no.1
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• pp.73-83
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• 2014

The objective of the this study was to investigate the binding capacity and removal ability of lactic acid bacterial strains obtained from Korean soybean paste for mutagenic heterocyclic amines (HCAs) formed during cooking of protein-rich food at high temperature. Among 19 strains identified by carbohydrate fermentation and 16S rRNA sequencing, the live cell or cell-free culture supernatant of Lactobacillus acidophilus D11, Enterococcus faecium D12, Pediococcus acidilactici D19, L. acidophilus D38, Lactobacillus sakei D44, Enterococcus faecalis D66, and Lactobacillus plantarum D70 inhibited the mutagenesis caused by either 3-amino-1,4-dimethyl-5H-pyrido[4,3-b] indole (Trp-P-1) or 3-amino-1-methyl-5H-pyrido[4,3-b] indole (Trp-P-2) in Salmonella typhimurium TA98 and TA100. The bacterial cells of the isolated strains showed greater binding activity than the pure cell wall, exopolysaccharide, and pepetidoglycan. The carbohydrate moieties of the cell wall or protein molecules on the cell surface have a significant role in binding Trp-P-1 and Trp-P-2, since protease, heating, sodium metaperiodate, or acidic pH treatments significantly (P<0.05) reduced the binding efficacy of the tested bacteria. Addition of metal ions or sodium dodecyl sulfate decreased the binding ability of E. faecium D12, L. acidophilus D38, and E. faecalis D66. Therefore, the binding mechanisms of these strains may consist of ion-exchange and hydrophobic bonds. Especially, the high mutagen binding by L. acidophilus D38 and L. plantarum D70 may reduce the accumulation or absorption of Trp-P-1 and Trp-P-2 in the small intestine via increased excretion of a mutagen-bacteria complex.