• KSII Transactions on Internet and Information Systems (TIIS)
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• 제9권11호
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• pp.4662-4679
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• 2015

Currently, the leakage of internal information has emerged as one of the most significant security concerns in enterprise computing environments. Especially, damage due to internal information leakage by insiders is more serious than that by outsiders because insiders have considerable knowledge of the system's identification and password (ID&P/W), the security system, and the main location of sensitive data. Therefore, many security companies are developing internal data leakage prevention techniques such as data leakage protection (DLP), digital right management (DRM), and system access control, etc. However, these techniques cannot effectively block the leakage of internal information by insiders who have a legitimate access authorization. The security system does not easily detect cases which a legitimate insider changes, deletes, and leaks data stored on the server. Therefore, we focused on the insider as the detection target to address this security weakness. In other words, we switched the detection target from objects (internal information) to subjects (insiders). We concentrated on biometrics signals change when an insider conducts abnormal behavior. When insiders attempt to leak internal information, they appear to display abnormal emotional conditions due to tension, agitation, and anxiety, etc. These conditions can be detected by the changes of biometrics signals such as pulse, temperature, and skin conductivity, etc. We carried out experiments in two ways in order to verify the effectiveness of the emotional recognition technology based on biometrics signals. We analyzed the possibility of internal information leakage detection using an emotional recognition technology based on biometrics signals through experiments.

• 한국산학기술학회논문지
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• 제14권8호
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• pp.3858-3865
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• 2013

이 연구는 2009년 지역사회 건강조사 자료를 활용하여 부모의 고위험 음주행동이 자녀의 건강행동에 미치는 영향을 조사하여 가족의 건강문제의 예방 및 관리를 위한 기초자료를 제공하고자 하는 목적에서 이루어 졌다. 대상은 19세 이상의 자녀를 둔 세대 중 고위험 음주에 노출된 16,383명을 선택하여 각 ID별로 부모가 고위험 음주자인 916명을 분류하여 빈도분석, 카이제곱 검정과 로지스틱 회귀분석을 실시하였다. 고위험 음주 부모의 자녀가 정상인 음주부모의 자녀에 비해 고위험 음주행동이(p<0.01)이 높았으며 부정적 건강행태에 영향을 미쳤다. 그러므로 고위험음주들에 대한 가족형 보건교육이 제도적으로 필요함을 고려하여 음주로 인한 문제의 해결이 가정에서부터 이루어져야 함을 제안한다.

• International Journal of Control, Automation, and Systems
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• 제3권3호
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• pp.493-501
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• 2005

A power plant simulation tool ('PowerSim') has been developed with 10 years experience from the development of a plant simulator for efficient modeling of a power plant. PowerSim is the first developed tool in Korea for plant simulation with various plant component models, instructor station function and the Graphic Model Builder (GMB). PowerSim is composed of a graphic editor using general purpose design software, a netlist converter, component models, the scheduler, Instructor Station and an executive. The graphic editor generates a netlist that shows the connection status of the various plant components from the Simdiagram, which is drawn by Icon Drag method supported by GUI environment of the PowerSim. Netlist Converter normalizes the connection status of the components. Scheduler makes scheduling for the execution of the device models according to the netlist. Therefore, the user makes Simdiagram based on the plant Pipe and Instrument Drawing (P&ID) and inputs the plant data for automatic simulating execution. This paper introduces Graphic Model Builder (GMB), instructor station, executive and the detailed introduction of thermal-hydraulic modeling. This paper will also introduce basic ideas on how the simulation Diagram, based on netlist generated from general purpose design software, is made and how the system is organized. The developed tool has been verified through the simulation of a real power plant.

• 대한지역사회영양학회지
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• 제7권5호
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• pp.639-653
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• 2002

The purpose of this study was to investigate the regional 야fferences in dietary supplement use and related factors among college students participating in nutritional education programs via the internet. The subjects in this study were 797 college students (male: 518, female: 279). A cross-sectional survey was conducted using a self-administered questionnaire about dietary supplement use, demographic characteristics, health-related lifestyles, nutrient intake, and data were collected via the internet and by mail. Dietary supplements were taken by 82.2% of subjects (males: 76.3%, females: 85.3%). There was a significant regional difference in supplement use (p<0.01). The supplements, used most frequent by male students in the Seoul and Incheon areas were lactic acid beverages and gagogi, in that order. Male students in the Kyunggi area used gagogi and lactic acid beverages in that order. Lactic acid beverages and Chinese medicine were used most frequently by male students in the Chungcheong area. Male students in the Kyungsang area used lactic acid beverages and water-soluble vitamins, in that order. Male students in Seoul and Kyungsang areas showed significantly higher percentage of keep on taking supplements compared to other areas (p<0.05). Both male and female students in the Seoul area had more frequent medical examinations, in comparison to students in other areas (p<0.05). Male students in the Kyungsang and Seoul areas took significantly more calcium (p<0.05) and iron (p<0.05), in comparison to students in other areas. Female students id the Kyunsang area took significantly more Vitamin A, phosphorous and iron (p<0.05), while those in the Seoul area took significantly more Vitamin C (p <0.01) and calcium (p<0.05) . Male students in the Chungcheong area took significantly less seaweed, in comparison to students in other areas (p<0.05) . Male students in the Seoul area had the highest amount of animal fat and oil, while those in the Incheon area ate the lowest amount of animal oil and fat (p<0.05). Female students in the Kyunggi area ate the highest amount of fruit, while those in the Incheon area ate the lowest amount of fruit (p< 0.05) , Female students in the Incheon area ate the highest amount of seaweed, while those in the Kyunggi area ate the lowest amount of seaweed (p<0.01). Therefore, it can be concluded that it is necessary to develop dietary supplements to optimize the nutritional status of college students in different areas of Korea.

• Asian-Australasian Journal of Animal Sciences
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• 제30권5호
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• pp.666-671
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• 2017

Objective: Aim of the current comparative study was to evaluate production outputs, reproduction efficiency and functional traits in dual-purpose Fleckvieh and Braunvieh cows, reared under temperate European conditions. Methods: A data-set from 414 Fleckvieh and 42 Braunvieh cows and 799 lactations was analysed. ID tag number, milk yield per milking session, number of steps/interval and milk conductivity were recorded and collected daily using AfiMilk 3.076 A-DU software (Afimilk Ltd., Kibbutz, Israel). Production and milk quality data were taken from the results of the official performance recordings and the reproductive outputs of cows were recorded by the research stations veterinarians. Comparisons between the two genotypes were carried out using the one way analysis of variance protocol, with categorical factor being considered the breed of cows. All the statistical inferences were carried out using Statistica software (StatSoft Inc., Tulsa, OK, USA). Results: Fleckvieh cows significantly outperformed ($p{\leq}0.05$) the Braunvieh herd, with average milk yields of $5,252.1{\pm}35.79kg$ and $4,897.6{\pm}128.94kg$, respectively. Age at first calving was significantly ($p{\leq}0.01$) influenced by the breed, with Fleckvieh heifers being more precocious ($32.8{\pm}0.29mo$) compared to those of Braunvieh breed ($35.7{\pm}0.84mo$). Reproduction efficiency as defined by the number of inseminations per gestation, calving interval, dystocia, days dry and days open, was not influenced by genotype (p>0.05). Incidences of sub-clinical mastitis, clinical mastitis, lameness and abortions were not influenced by the breed factor (p>0.05). Stay-ability of cows was significantly ($p{\leq}0.001$) influenced by genotype, with Braunvieh cows having an average age at culling of $117.88{\pm}11.78$ months compared to $90.88{\pm}2.89$ months in Fleckvieh. Conclusion: Overall, results have shown that genotype significantly influenced milk yield, age at first calving and longevity.

• 생명과학회지
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• 제23권4호
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• pp.586-594
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• 2013

단백질 번역 후 O-GlcNAc 수식은 단백질 조절의 새로운 기전으로 대두되고 있다. 전통적인 당수식과 달리 O-GlcNAc 수식은 단 한번의 O-GlcNAc 전달로 이루어지며, 핵 및 세포질단백질 모두에 수식될 수 있다. O-GlcNAc은 이 분자를 끝으로 하는 최종수식으로 생각되어 왔으나, 최근의 논문(J Proteome Res. 2011 10:2725-2733)은 AP180 단백질에 O-GlcNAc-P가 존재함을 보고하였다. 이 논문은 O-GlcNAc-P가 일반적인 단백질수식인지에 대한 중요한 질문을 던진다. 이에 답하고자 저자들은 HEK293T 세포에 O-GlcNAc 인산화효소 NAGK를 DsRed2에 연결한 DsRed2-$NAGK_{WT}$ 혹은 효소활성이 없는 돌연변이 NAGK를 표현하는 DsRed2-$NAGK_{D107A}$를 표현시키고, 단백질 추출물을 얻어 2D-PAGE로 분리한 후 인산화 정도를 측정하여, $NAGK_{WT}$에 의하여 인산화가 증가되는 15개의 단백질 스폿을 선별하였다. 이 가운데 7개 스팟을 동정한 결과 2개의 스폿은 O-GlcNAc 수식 단백질인 $HSP90{\beta}$, 다른 2개의 스폿도 O-GlcNAc 수식 단백질인 ENO1로 동정되었으며, 나머지(dUTP nucleotidohydrolase mitochondrial isoform 2, glutathione S-transferase P, grp94)는 O-GlcNAc 수식 여부를 아직 모르는 단백질이였다. NAGK에 의하여 O-GlcNAc 단백질의 인산화가 증가된다는 사실은 O-GlcNAc이 인산화되어 O-GlcNAc-P로 수식됨을 시사하며, 따라서 본 연구의 결과는 O-GlcNAc이 최종 수식이 아님을 지지한다.

• 한국가스학회지
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• 제22권2호
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• pp.1-20
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• 2018

Despite many measures, still from time to time catastrophic events occur, even after reviewing potential scenarios with HAZID tools. Therefore, it is evident that in order to prevent such events, answering the question: "What can go wrong?" requires more enhanced HAZID tools. Recently, new system based approaches have been proposed, such as STPA (system-theoretic process analysis) and Blended Hazid, but for the time being for several reasons their availability for general use is very limited. However, by making use of available advanced software and technology, traditional HAZID tools can still be improved in degree of completeness of identifying possible hazards and in work time efficiency. The new HAZID methodology proposed here, the Data-based semi-Automatic HAZard IDentification (DAHAZID), seeks to identify possible scenarios with a semi-automated system approach. Based on the two traditional HAZID tools, Hazard Operability (HAZOP) Study and Failure Modes, Effects, and Criticality Analysis (FMECA), the new method will minimize the limitations of each method. This will occur by means of a thorough systematic preparation before the tools are applied. Rather than depending on reading drawings to obtain connectivity information of process system equipment elements, this research is generating and presenting in prepopulated work sheets linked components together with all required information and space to note HAZID results. Next, this method can be integrated with proper guidelines regarding process safer design and hazard analysis. To examine its usefulness, the method will be applied to a case study.

• 한국안전학회지
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• 제24권1호
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• pp.31-36
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• 2009

This paper focuses on techniques of improving refinery reliability, availability, and profitability. Our team developed a corrosion control document(CCD) for processing of the crude distillation unit(CDU). Recent study shows the loss due to corrosion in US is around $276 billion. It's a big concern for both managers and engineers of refinery industry. The CCD consists of numerous parts namely damage mechanism(DM), design data, critical reliability variable(CRV), guidelines, etc. The first step in the development of CCD is to build material selection diagram(MSD). Damage mechanisms affecting equipments and process need to be chosen carefully based on API 571. The selected nine DM from API 571 are (1) creep/stress rupture, (2) fuel ash corrosion, (3) oxidation, (4) high temperature sulfidation, (5) naphthenic acid corrosion, (6) hydrochloric acid(HCL) corrosion, (7) ammonium chloride(salt) corrosion, (8) wet $H_2S$ corrosion, and (9) ammonia stress corrosion cracking. Each DM related to corrosion of CDU process was selected by design data, P&ID, PFD, corrosion loop, flow of process, equipment's history, and experience. Operating variables affecting severity of DM are selected in initial stage of CRV. We propose the guidelines for reliability of equipments based on CRV. The CCD has been developed on the basis of the corrosion control in refinery industry. It also improves the safety of refinery process and reduces the cost of corrosion greatly.

• Tuberculosis and Respiratory Diseases
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• 제85권4호
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• pp.349-357
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• 2022

Background: The most consistently identified mortality determinants for the new coronavirus 2019 (COVID-19) infection are aging, male sex, cardiovascular/respiratory diseases, and cancer. They were determined from heterogeneous cohorts that included patients with different disease severity and previous conditions. The main goal of this study was to determine if activities of daily living (ADL) dependence measured by Barthel's index could be a predictor for COVID-19 mortality. Methods: A prospective cohort study was performed with a consecutive sample of 340 COVID-19 patients representing patients from all over the northern region of Portugal from October 2020 to March 2021. Mortality risk factors were determined after controlling for demographics, ADL dependence, admission time, comorbidities, clinical manifestations, and delay-time for diagnosis. Central tendency measures were used to analyze continuous variables and absolute numbers (proportions) for categorical variables. For univariable analysis, we used t test, chi-square test, or Fisher exact test as appropriate (α=0.05). Multivariable analysis was performed using logistic regression. IBM SPSS version 27 statistical software was used for data analysis. Results: The cohort included 340 patients (55.3% females) with a mean age of 80.6±11.0 years. The mortality rate was 19.7%. Univariate analysis revealed that aging, ADL dependence, pneumonia, and dementia were associated with mortality and that dyslipidemia and obesity were associated with survival. In multivariable analysis, dyslipidemia (odds ratio [OR], 0.35; 95% confidence interval [CI], 0.17-0.71) was independently associated with survival. Age ≥86 years (pooled OR, 2.239; 95% CI, 1.100-4.559), pneumonia (pooled OR, 3.00; 95% CI, 1.362-6.606), and ADL dependence (pooled OR, 6.296; 95% CI, 1.795-22.088) were significantly related to mortality (receiver operating characteristic area under the curve, 82.1%; p<0.001). Conclusion: ADL dependence, aging, and pneumonia are three main predictors for COVID-19 mortality in an elderly population.

• 대한한의학방제학회지
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• 제14권1호
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• pp.105-119
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• 2006

Objectives & Methods : This present study was performed to investigate the effect of Hwadamtongrak-Tang extract (HTT) on the regulation of cerebral hemodynamics in terms of regional cerebral blood flow (rCBF) and mean arterial blood pressure (MABP)] in normal and cerebral ischemic rats. Also the effects of HTT on changes in local blood flow, inhibition of LD H activity in neuronal cells, and levels of cytokine production in the serum were determined in the ischemic rat model. The major findings are summarized below. Results : 1. HTT significantly increased rCBF in a dose-dependent manner, but MABP was not changed by HTT treatment. These results suggest that HTT may increase rCBF by dilating cerebral arterial diameter. 2. HTT-induced increase in rCBF was blocked by pretreatment with cyclooxygenase inhibitor indomethacin (IDN, 1 mg/kg, i.p.) and MABP was significantly increased by ID N. 3. Pretreatment of methylene blue $(MTB,\;10\;{\mu}g/kg,\;i.p.)$, an inhibitor of guanylate cyclase, significantly decreased both rCBP and MABP in HTT-treated rats. 4. HTT treatment significantly increased rCBP to a stable level during the period of cerebral reperfusion. 5. HTT significantly inhibited LD H activity in neuronal cells, suggesting a neuroprotection by HTT. 6. Serum interleukin $(IL)-1{\beta}$ and tumor necrosis factor $(TNF)-{\alpha}$ levels were significantly decreased in the femoral artery 1 hr after middle cerebral arterial occlusion in HTT-treated rats. IL-10 levels in the serum were significantly increased by HTT treatment whereas transforming growth factor $(TGF)-{\beta}$ levels were similar between HTT-treated and control groups. 7. Serum interleukin $(IL)-1{\beta}$ and tumor necrosis factor $(TNF)-{\alpha}$ levels were significantly decreased in the femoral artery 1 hr after reperfusion in HTT-treated rats. Serum IL-10 levels were significantly decreased in HTT-treated rats compared with the control group, and no significant changes in $(TGF)-{\beta}$ in the serum were observed by HTT treatment. Conclusions: The present data suggest that HTT may have an anti-ischemic effect via the improvement of cerebral hemodynamics and thus protect the brain from ischemic damage.