• Title/Summary/Keyword: Oxidization

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Biological Safety and Anti-hepatofibrogenic Effects of Brassica rapa (Turnip) Nanoparticle

  • Park, Dae-Hun;Li, Lan;Jang, Hyung-Kwan;Kim, Young-Jin;Jang, Ja-June;Choi, Yeon-Shik;Park, Seung-Kee;Lee, Min-Jae
    • Molecular & Cellular Toxicology
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    • v.5 no.4
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    • pp.317-322
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    • 2009
  • Hepatic fibrosis is one of chronic liver diseases which spread in worldwide and it has high risk to turn advanced cirrhosis and hepatocellualr carcinoma. Brassica family has been produced for commercial purpose and in Korea Brassica rapa (Turnip) is cultivated in Ganghwa County, Gyeonggi-do Korea and used for making Kimchi. Recently pharmacological effects of turnip have been known; diabete mellitus modulation, alcohol oxidization, and fibrosis inhibition. In previous study we found antifibrogenic effect of turnip water extract and in this study we made turnip nanoparticle to promote turnip delivery into liver. At the same time we assessed the biological safety of turnip nanoparticle. Thioacetamide (TAA) induced hepatic nodular formation and fibrosis (mean of fibrosis score: 4). However, 1% turnip nanoparticle inhibited TAA-induced hepatic nodular formation and fibrosis (mean of fibrosis score: 2-3). Activities of serum enzymes (aspartic acid transaminase (AST), alanine transaminase (ALT), and total bilirubin (T-Bil)), complete blood count (CBC), and the appearance of organs were not different from control and 1% turnip nanoparticle treatment. Conclusively 1% turnip nanoparticle significantly reduced TAA-induced hepatic fibrosis and was safe in 7-weeks feeding.

A Study on the Thermal Degradation Properties of Epoxy Resin for Cast Resin Transformer (몰드변압기용 에폭시 수지의 열 열화특성에 관한 연구)

  • Lim, Kyung-Bum;Nam, Ki-Dong;Kim, Ki-Hwan;Park, Su-Hong;Hwang, Myung-Hwan
    • Fire Science and Engineering
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    • v.22 no.2
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    • pp.44-48
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    • 2008
  • In this paper, we measured a contact angle, surface resistivity and XPS to study the thermal aging characteristics of the epoxy resin for cast resin transformer. As a result of this experiment, we found that the contact angle increases up to $200^{\circ}C$ as it causes a re-crosslinking on the surface, but starts decreasing at $250^{\circ}C$ as it causes heat condensation. As a result of examining the oxygen/carbon peaks through the XPS analysis, we obtained a higher oxygen peak vs. carbon in the first untreated sample, but it showed the opposite trend after heat treatment. That rise in the carbon peak continued up to $200^{\circ}C$, but decreased again at the temperatures above. That's because it kept forming a stable surface structure up to $200^{\circ}C$ but its carbon combination got destroyed due to a rapid oxidization at $250^{\circ}C$. And a conduction path was formed easily with the hydrophile property caused by rapid surface activation.

Production of Hydrogen and Carbon Black Using Natural Gas Thermal Decomposition Method (천연가스 열분해법에 의한 수소 및 탄소 제조)

  • Jang, Hun;Lee, Byung Gwon;Lim, Jong Sung
    • Clean Technology
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    • v.10 no.4
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    • pp.203-213
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    • 2004
  • Natural gas thermal decomposition method is the technology of converting natural gas (methane) into hydrogen and carbon at high temperature. The most advantage of thermal decomposition method is that hydrogen and carbon can be produced without emitting carbon dioxide. In this study, the generation of hydrogen and carbon was investigated by this natural gas (methane) thermal decomposition method. We found that pyrocarbon was created on the surface of reactor, carbon black was deposited on the pyrocarbon and final plugging phenomenon took place. To solve this problem, we tried several attempts such as introduction of double pipe reactor instead of single pipe reactor or oxidization of carbon black using $O_2$ or $CO_2$ at regular intervals of reaction. Therefore, some plugging phenomenon was resolved by this methods. Also, carbon particle size was measured by SEM (Scanning Electron Microscope) image and the size was about 200 nm.

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Effects of Thermal Aging of Natural Rubber Bearing on Seismic Performance of Bridges (천연고무받침의 열 노화가 교량 내진성능에 미치는 영향)

  • Oh, Ju;Jung, Hie-Young
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.33 no.3
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    • pp.855-864
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    • 2013
  • The dynamic characteristics of natural rubber bearings, which are used as isolator, are dependent on the main rubber's dynamic behaviors and nonlinear properties. Rubber materials tend to undergo an aging process under the influence of mechanical or environmental factors, so they inevitably end up facing damage. A main cause of aging like this is known to be oxidization, which occurs through the heat of reaction at high temperatures. Accordingly, in this study an accelerated thermal aging test was carried out in order to compare the characteristic values of the bearings before and after thermal aging occurs. As a result of this experiment, it was found that a thermal aging phenomenon could have some effects on shear stiffness, energy absorption, and equivalent damping coefficients of the bearings. Furthermore, a deterioration in the dynamic properties of the natural rubber bearings caused by the thermal aging was applied to an actual bridge and then the effects of such thermal aging on the seismic performance of the bridge were also compared and analyzed based on numerical analysis. As a result of this analysis, it was found that the changes in the basic properties of the natural rubber bearings caused by the thermal aging bring only a minor effect on the seismic performance of bridges.

Study on Application of Urethane Materials for Hardening of Metal Artifacts (금속유물 강화처리를 위한 우레탄 수지의 적용성 연구)

  • Lee, Ho-Yeon;Wi, Koang-Chul
    • Journal of Conservation Science
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    • v.27 no.4
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    • pp.415-420
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    • 2011
  • Urethane coating agent was made up in order to prevent corrosion on metal relics. This urethane coating agent was designed to solve problems linked to gloss and discoloration caused by existing acrylic coating agent which is mainly applied to metal relics. For the purpose, the urethane coating agent was made up which has lower gloss and slight color change. This coating agent formed thinner coating layer with excellent adhesion compared to the existing agent and has outstanding resistance to the surface oxidization of metal relics and water repellent on the surface. In addition, the agent is considered a stable coating agent replacing current acrylic coating agent with showing easy dissolution in organic solvents such as acetone, toluene and xylene with excellent result in reversible reaction.

Influence of Aging of Lead Rubber Bearing on Seismic Performance of Bridges (납고무받침의 노화가 교량의 내진성능에 미치는 영향)

  • Park, Seong-Kyu;Oh, Ju
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.32 no.2A
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    • pp.109-116
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    • 2012
  • The dynamic properties of lead rubber bearings, which are used as isolator, are dependent on the main rubber's dynamic behaviors and nonlinear qualities. Rubber materials tend to undergo an aging process under the influence of mechanical or environmental factors, so they can end up inevitably facing damage. A main cause of such aging is known to be oxidization, which occurs through the heat of reaction at high temperatures. Accordingly, in this study an accelerated thermal aging test was carried out in order to compare the characteristic values of the bearings with each other before and after thermal aging occurs. As a result of this experiment, it was found that a thermal aging phenomenon could have an effect on shear stiffness, energy absorption, and equivalent damping coefficients. Furthermore, a decline in the dynamic properties of the lead rubber bearings by means of the thermal aging process was applied to an actual bridge and the effects of such thermal aging on the seismic performance of the bridge were also compared and analyzed based on numerical analysis. As a result of this analysis, it was found that the changes in the basic properties of the lead rubber bearings have a minor effect on the seismic performance of bridges.

Physiochemical Characteristics of Extruded Angelica gigas Nakai Depending on the Extrusion Processing Parameter (압출성형 공정에 따른 참당귀 추출물의 이화화적 특성)

  • Lee, Hee Jung;Jeong, Heon Sang;Park, Chun Geon;Lee, Jeong Hoon;Park, Chung Berm;Kim, Chong Tai;Choi, Ae Jin
    • Korean Journal of Medicinal Crop Science
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    • v.22 no.5
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    • pp.349-362
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    • 2014
  • This study was designed to maximize extract yields of functional components in Angelica gigas Nakai by extrusion process. In addition, the optimizing condition of the extrusion process was established to increase the extraction of the functional components in A. gigas. The total polyphenol was increased by 40% compared to a control. And the optimizing condition was that the screw speed was 62.76 rpm, the amount of A. gigas powder was 34.79 kg/h, and the amount of water was 4.44 kg/h. The result of antioxidant activities of A. gigas extrusion, the inhibition of oxidization had the effect of 10.29 ~ 14.59% compared to a control. The content of decursin and decursinol angelate, which were index components, was 6.37%; it was increased by 16.64% compared to a control (5.31%) and showed a significantly difference (p < 0.05). And the optimizing condition was the screw speed 93.71 rpm, the amount of A. gigas powder was 28.67 kg/h, and the amount of water was 9.9 kg/h.

A Study on Bond Strength of Procelain with Non Precious Alloy (도재전장관용 비귀금속합금과 도재의 융착결합에 관한 연구)

  • Kang, Sung-Hyun
    • The Journal of Korean Academy of Prosthodontics
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    • v.18 no.1
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    • pp.49-57
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    • 1980
  • The adhesive mechanisms on the metal-ceramic restorations have been reported to be mechanical interlocking, chemical bonding, compressive force, and Van der Waal's force, etc. Of these, the mechanical interlocking and chemical bonding forces are thought to affect the adhesive force between Ni-Cr alloy and porcelain. This study investigates the adhesion of Ni-Cr alloy to porcelain according to surface treatment. For this purpose, the following experiments were made; The compositions of Ni-Cr alloy as cast by emission spectrograph, and the oxides produced on Ni-Cr alloy during degassing at $1850^{\circ}F$ for 30 minutes in air and in vacuum were analyzed by X-ray diffractograph. The metal phases of Ni-Cr alloy were observed according to porcelain-baking cyclic heat treatment by photo microscope and the distribution and the shift of elements of Ni-Cr alloy and porcelain and the failure phases between Ni-Cr alloy and porcelain by scanning electron microscope. The adhesive force between Ni-Cr alloy and porcelain was measured according to surface treatment with oxidization and roughening by Instron Universal Testing Machine. Results were as follows; 1. The metal phases of Ni-Cr alloy as cast and degassing state showed the enlarged and fused core, but when subjected to porcelain-baking cyclic heat treatment, showed a dendrite growing. 2. The kinds of metal oxides produced on Ni-Cr alloy during degassing were found to be NiO and $Cr_2O_3$. 3. The distribution of elements at the interface of Ni-Cr alloy and porcelain in degassing state showed demarcation line, but in roughening state, showed mechanical interlocking phase. 4. The shift of elements at the interface occurred in both states, but the shift amount was found to be larger in roughening than in degassing. 5. The adhesive force between Ni-Cr alloy and porcelain was found to be $3.45{\pm}0.93kg/mm^2$, in degassing and $3.82{\pm}0.99kg/mm^2$, in roughening. 6. The failure phase between Ni-Cr alloy and porcelain showed the mixed type failure.

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Anti-obesity effects of hot water extract from Wasabi (Wasabia japonica Matsum.) leaves in mice fed high-fat diets

  • Yamasaki, Masayuki;Ogawa, Tetsuro;Wang, Li;Katsube, Takuya;Yamasaki, Yukikazu;Sun, Xufeng;Shiwaku, Kuninori
    • Nutrition Research and Practice
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    • v.7 no.4
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    • pp.267-272
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    • 2013
  • The anti-obesity effects of a hot water extract from wasabi (Wasabia japonica Matsum.) leaves (WLE), without its specific pungent constituents, such as allyl-isothiocyanate, were investigated in high fat-diet induced mice. C57J/BL mice were fed a high-fat diet (control group) or a high-fat diet supplemented with 5% WLE (WLE group). Physical parameters and blood profiles were determined. Gene expression associated with lipid metabolism in liver and white adipose tissue were analyzed. After 120 days of feeding, significantly lower body weight gain, liver weight and epididymal white adipose tissue weight was observed in the WLE group compared to the control group. In liver gene expression within the WLE group, PPAR${\alpha}$ was significantly enhanced and SREBP-1c was significantly suppressed. Subsequent downstream genes controlled by these regulators were significantly suppressed. In epididymal white adipose tissue of the WLE group, expression of leptin, PPAR${\gamma}$, and C/EBP${\alpha}$ were significantly suppressed and adiponectin was significantly enhanced. Acox, related to fatty acid oxidization in adipocytes, was also enhanced. Our results demonstrate that the WLE dietary supplement induces mild suppression of obesity in a high-fat diet induced mice, possibly due to suppression of lipid accumulation in liver and white adipose tissue.

Developed Stand alone PMS for ESS Safety Operation (ESS 안전 운영을 위한 독립형 PMS 개발)

  • Oh, Hong-Geun;Kim, Chul-Won
    • The Journal of the Korea institute of electronic communication sciences
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    • v.14 no.2
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    • pp.351-360
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    • 2019
  • Recently, the use of ESS facilities has been increased under the government's energy policy and at the same time, the various accident incidents such as fire and explosion occurred. Currently the ESS is installed as integrated ESS which includes PMS(: Power Management System), However, when the accident occurs, this system has high possibilities of losing the data due to oxidization, and the administrator cannot respond promptly. Therefore, in this paper, by constructing a separate WAS and data storage, it is possible to separate the main functions of the conventional system, to enable external EMS operation, and at the same time to quickly respond to the cause and cause of the accident occurrence. We will propose the development of a standalone PMS that is possible to respond.