• Genomics & Informatics
• /
• v.14 no.4
• /
• pp.196-204
• /
• 2016

Many researchers have found that one of the most important characteristics of the structure of linkage disequilibrium is that the human genome can be divided into non-overlapping block partitions in which only a small number of haplotypes are observed. The location and distribution of haplotype blocks can be seen as a population property influenced by population genetic events such as selection, mutation, recombination and population structure. In this study, we investigate the effects of the density of markers relative to the full set of all polymorphisms in the region on the results of haplotype partitioning for five popular haplotype block partition methods: three methods in Haploview (confidence interval, four gamete test, and solid spine), MIG++ implemented in PLINK 1.9 and S-MIG++. We used several experimental datasets obtained by sampling subsets of single nucleotide polymorphism (SNP) markers of chromosome 22 region in the 1000 Genomes Project data and also the HapMap phase 3 data to compare the results of haplotype block partitions by five methods. With decreasing sampling ratio down to 20% of the original SNP markers, the total number of haplotype blocks decreases and the length of haplotype blocks increases for all algorithms. When we examined the marker-independence of the haplotype block locations constructed from the datasets of different density, the results using below 50% of the entire SNP markers were very different from the results using the entire SNP markers. We conclude that the haplotype block construction results should be used and interpreted carefully depending on the selection of markers and the purpose of the study.

• The Korean Journal of Cytopathology
• /
• v.15 no.1
• /
• pp.45-51
• /
• 2004

It is important to recognize the pathognomonic cytologic findings of chordoma, because of overlapping cytologic features between chordoma, chondrshdosarcoma, myxofilbrillary ependymoma, and metastatic adenocarcinoma. We reviewed the cytomorphologic features of 5 cases of chordoma diagnosed by fine needle aspiration cytology at Korean Cancer Center Hospital from 1987 to 2003. Clinical and radiographic findings of each case were reviewed. Four males and one female (29-54 years) had tumors involving the sacrum. Pain was the presenting symptom in 4 cases. The three cases showed moderate to high cellularity. In all cases, typical physaliferous cells with or without cytoplasmic processes were noted. In two cases, the background was myxoid with single scattered cells. Cell clusters showing cord-like arrangement were occasionally seen. The single or clustered cells showed mild cellular pleomorphism with slightly increased nuclear/cytoplasmic ratio. Mitotic figures were not seen. In our review, the recognition of physaliferous cells is the most important feature to diagnose chordoma and to differentiate it from other lesions mimicking chordoma.

• Journal of Advanced Navigation Technology
• /
• v.6 no.1
• /
• pp.77-83
• /
• 2002

The emergence of Bluetooth as a radio interface scheme has allowed electronic devices to be instantly interconnected as ad-hoc networks. These short range ad-hoc wireless networks are called piconets, operated in the unlicensed 2.45 GHz ISM(Industrial, Scientific, Medical) band where up to eight devices may be used to configure single or overlapping piconets. In this paper, we have simulated the PER(Packet Error Rate), the ratio of received packet and payload BER(Bit Error Rate) of piconet with packet types of Bluetooth ACL/SCO(Asynchronous Connection Less/Synchronous Connection Oriented) link over wireless ad-hoc environment. The Rayleigh fading effects are considered as channel model, and the simulation results are based on the baseband model of Bluetooth specification. From the simulation results, the PER and the throughput of Bluetooth piconet are sensibly affected by the packet type of ACL/SCO link.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
• /
• v.25 no.3
• /
• pp.365-371
• /
• 2014

It is essential for the combined military weapon system to be equipped with interoperability for the efficient combat operation in the modern warfare environment. Since most of modern military systems utilize the electromagnetic wave for the radio communication in the network-centric warfare system, they can be vulnerable to the mutual interference among the adjacent combined military systems. In this paper, the typical radio communication systems are modeled with the modulation types of both spread and non-spread spectrum system. The various interference signals were generated for the simulation of the mutual interference influence from the adjacent radar and communication systems. The simulation results show that the detection performance of the victim communication receiver is seriously affected by the various interferences such as the types of modulation and the ratio of the overlapping bandwidth of the adjacent interferers. This result will be useful for defining the criteria of the interference protection in the combined military system for the interoperability in the future.

• Journal of the Korea Institute of Information and Communication Engineering
• /
• v.14 no.1
• /
• pp.89-96
• /
• 2010

In this paper, we proposed a method about improving face tracking efficiency of face detection for AF system using the faces to the ROI. The conventional face detection system detecting faces based skin color uses the ratio of skin pixels of the present frame to detected face regions of the past frame to track the faces. The tracking method is superior in the stability of the regions but it is inferior in the face tracking efficiency. We proposed a face tracking method using the area of the overlapping region in the detected face regions of the past frame and the present frame to improve the tracking efficiency. The proposed face tracking efficiency demonstration was performed by making a film of face detection with face tracking in real-time and using the moving traces of the detected faces.

• Journal of the Korea Convergence Society
• /
• v.11 no.1
• /
• pp.181-186
• /
• 2020

Civil technologies and parts occupy big ratio in military vehicle as military supply goods were commercialized. In case of the military vehicle engine, the civil purposed engine has been militarized without developing engine for defense industry. Because of this, it happens that Euro-5 version is mounted in spite of Euro-6 at present because the civil laws on the civil purpose engine and required operational capability for militarization are applied by overlapping. Therefore, this study focused on current situation and issues on the military vehicle emission regulation and suggested how to improve through analyzing the theses, articles, Korean laws and systems. For improving methods, imposing the emission certification duty and exempting the certification for the vehicle of high strategical importance were suggested through aligning the related laws. Consequently, it is expected that this study will be used for basics of checking the civil laws and connection with military systems for commercialization of military supplied goods.

• Journal of the Institute of Electronics and Information Engineers
• /
• v.50 no.10
• /
• pp.162-170
• /
• 2013

In recent years, the interests and needs of the Pedestrian Protection System (PPS), which is mounted on the vehicle for the purpose of traffic safety improvement is increasing. In this paper, we propose a pedestrian candidate window extraction and unit cell histogram based HOG descriptor calculation methods. At pedestrian detection candidate windows extraction stage, the bright ratio of pedestrian and its circumference region, vertical edge projection, edge factor, and PCA reconstruction image are used. Dalal's HOG requires pixel based histogram calculation by Gaussian weights and trilinear interpolation on overlapping blocks, But our method performs Gaussian down-weight and computes histogram on a per-cell basis, and then the histogram is combined with the adjacent cell, so our method can be calculated faster than Dalal's method. Our PCA reconstruction error based pedestrian detection candidate window extraction method efficiently classifies background based on the difference between pedestrian's head and shoulder area. The proposed method improves detection speed compared to the conventional HOG just using image without any prior information from camera calibration or depth map obtained from stereo cameras.

• KSII Transactions on Internet and Information Systems (TIIS)
• /
• v.9 no.6
• /
• pp.2230-2250
• /
• 2015

Multiple projectors with partially overlapping regions can be used to project a seamless image on a large projection surface. With the advent of high-resolution photography, such systems are gaining popularity. Experts set up such projection systems by subjectively identifying the types of errors induced by the system in the projected images and rectifying them by optimizing (correcting) the parameters associated with the system. This requires substantial time and effort, thus making it difficult to set up such systems. Moreover, comparing the performance of different multi-projector display (MPD) systems becomes difficult because of the subjective nature of evaluation. In this work, we present a framework to quantitatively determine the quality of an MPD system and any image projected using such a system. We have divided the quality assessment into geometric and photometric qualities. For geometric quality assessment, we use Feature Similarity Index (FSIM) and distance-based Scale Invariant Feature Transform (SIFT). For photometric quality assessment, we propose to use a measure incorporating Spectral Angle Mapper (SAM), Intensity Magnitude Ratio (IMR) and Perceptual Color Difference (ΔE). We have tested the proposed framework and demonstrated that it provides an acceptable method for both quantitative evaluation of MPD systems and estimation of the perceptual quality of any image projected by them.

• Asian Pacific Journal of Cancer Prevention
• /
• v.15 no.8
• /
• pp.3561-3566
• /
• 2014

Background: Recurrent nasopharyngeal carcinoma (NPC) after previous radiotherapy is challenging. There is no standard approach for salvage treatment. Here we present toxicity and treatment results for recurrent NFC patients who underwent fractionated stereotactic radiotherapy (FSRT) as second line radiotherapy (RT). Materials and Methods: Between April 2009 and July 2012, 24 patients, with a male to female ratio of 3:1, were treated with CykerKnife$^{(R)}$ FSRT for recurrent NFC in our institution. Seven out of 24 patients had metastatic recurrent disease. Median age was 53 years (range, 20-70 years). Initial RT dose was 70Gy. The time period between initial RT and FSRT was a median of 33.2 months. The median prescription dose for FSRT was 30Gy (range, 24-30 Gy) in a median of 5 fractions (range, 4-6). Results: The median follow-up for all patients was 19.5 months (IQR: 12.2.-29.2 months). The locoregional control; progression free survival and overall survival (OS) rates for 1-, 2- and 3-year were 64%, 38%, 21%; 60%, 30%, 17% and 83%, 43%, 31%, respectively. Median OS for the entire cohort was 22 months (95% CI: 16.5-27.5). On multivariate analysis recurrent tumor stage was the only prognostic factor for OS (p=0.004). One patient exhibited grade III temporal lobe necrosis. One died because of grade IV mucositis and overlapping infection. Conclusions: The treatment of recurrent NPC is controversial. Fractionated stereotactic radiotherapy is promising. However, the published trials are heterogeneous with respect to the selection criteria and treatment details. Prospective studies with long term follow-up data are warranted.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
• /
• v.30 no.2
• /
• pp.153-162
• /
• 2012

In this paper, we propose a new shape similarity measure for M:N polygon pairs regardless of different object cardinalities in the pairs. The proposed method compares the projections of two shape functions onto Zernike polynomial basis functions, where the shape functions were obtained from each overall region of objects, thus not being affected by the cardinalities of object pairs. Moments with low-order basis functions describe global shape properties and those with high-order basis functions describe local shape properties. Therefore several moments up to a certain order where the original shapes were similarly reconstructed can efficiently describe the shape properties thus be used for shape comparison. The proposed method was applied for the building objects in the New address digital map and a car navigation map of Seoul area. Comparing to an overlapping ratio method, the proposed method's similarity is more robust to object cardinality.