• Journal of Periodontal and Implant Science
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• v.28 no.1
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• pp.177-185
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• 1998

Periodontal disease and/or loss of teeth brings pathologic tooth migration that can result in esthetic and occlusal problems. Diastema and general spacing of the teeth, particularly in the anterior segments of the dentition are frequently developed in individuals with advanced periodontal disease. Thus, the overall treatment plan for a patent with advanced periodontal disease often involves periodontal orthodontic combined therapy. Orthodontic treatment in adults with periodontal disease is restricted to tooth alignment with special caution. Indirect bonding can achieve accurate bracket placement. A 38 year old woman with adult periodontitis was treated by periodontal therapy. Subsequently, her diastema was orthodontically corrected by indirect bonding technique. It must be an appropriate case report of periodontal-orthodontic combined therapy.

• Journal of Communications and Networks
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• v.13 no.6
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• pp.664-677
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• 2011

In order to control interference and improve spectrum efficiency in the femtocell and macrocell overlaid system (FMOS), we propose a joint frequency bandwidth dynamic division, clustering and power control algorithm (JFCPA) for orthogonal-frequency-division-multiple access-based downlink FMOS. The overall system bandwidth is divided into three bands, and the macro-cellular coverage is divided into two areas according to the intensity of the interference from the macro base station to the femtocells, which are dynamically determined by using the JFCPA. A cluster is taken as the unit for frequency reuse among femtocells. We map the problem of clustering to the MAX k-CUT problem with the aim of eliminating the inter-femtocell collision interference, which is solved by a graph-based heuristic algorithm. Frequency bandwidth sharing or splitting between the femtocell tier and the macrocell tier is determined by a step-migration-algorithm-based power control. Simulations conducted to demonstrate the effectiveness of our proposed algorithm showed the frequency-reuse probability of the FMOS reuse band above 97.6% and at least 70% of the frequency bandwidth available for the macrocell tier, which means that the co-tier and the cross-tier interference were effectively controlled. Thus, high spectrum efficiency was achieved. The simulation results also clarified that the planning of frequency resource allocation in FMOS should take into account both the spatial density of femtocells and the interference suffered by them. Statistical results from our simulations also provide guidelines for actual FMOS planning.

• Korean Journal of Veterinary Service
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• v.30 no.3
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• pp.445-457
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• 2007

This report studied the individual number, their favorite habitat, and change pattern of family and group number in Cheolwon Basin, starting in the early Oct. 2004 until late March. 2005 to investigate the ecological features of the Red-crowned Crane and the White-naped Crane. The Cranes arrived Cheolwon Basin in mid-October until next mid-March, and passed the winter in mid-November until next late-February The most visiting number amounted to 550 individuals and, that period was the most frosting mid-January to mid-February. The White-naped Crane visited Cheolwon Basin in autumn, the early winter and spring. Approximately, the wintering-number is 550 individuals, also, the mid-March was the peak-period of arrival and, the number amounted to 2,162 individuals. The cranes chose the farming area around mountains as their wintering habitat and were less likely to choose the farming area around lake as habitat. The Red-crowned Crane and the White-naped Crane showed the different periodical pattern in familial and group numbers. In case of the crane, the familial pattern was stable, but varied in grouping number, and this pattern was similar to the variation of overall individual number. And, also, the most grouping number was shown in the most freezing period of wintering period. The White-naped Crane showed the similar pattern of the Red-crowned Crane that is, stable family number and varying group number, this pattern affected the total number of entire individuals. Grouping number increased in migration period. Parasite infection rate is G japonensis 35.0%, G vipio 38.7%.

• BMB Reports
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• v.50 no.7
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• pp.384-389
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• 2017

The Nogo-B receptor (NgBR) is necessary for not only Nogo-B-mediated angiogenesis but also vascular endothelial growth factor (VEGF) -induced angiogenesis. However, the molecular mechanisms underlying the regulatory role of the VEGF-NgBR axis in angiogenesis are not fully understood. Here, we report that miR-26a serves as a critical regulator of VEGF-mediated angiogenesis through directly targeting NgBR in endothelial cells (ECs). Stimulation of ECs by VEGF increased the expression of NgBR and decreased the expression of miR-26a. In addition, miR-26a decreased the VEGF-induced migration and proliferation of ECs. Moreover, miR-26a overexpression in ECs decreased the VEGF-induced phosphorylation of the endothelial nitric oxide synthase (eNOS) and the production of nitric oxide, which is important for angiogenesis. Overall, these data suggest that miR-26a plays a key role in VEGF-mediated angiogenesis through the modulation of eNOS activity, which is mediated by its ability to regulate NgBR expression by directly targeting the NgBR 3'-UTR.

• Geophysics and Geophysical Exploration
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• v.2 no.3
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• pp.149-153
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• 1999

The study was performed as a part of 3-D exploration project of the South Con Son basin, where Korea National Oil Co. (KNOC) and SHELL Company are performing joint operation. In the structurally complex area, seismic facies or lap-out patterns, which are usually the tools for the conventional seismic stratigraphy developed by Exxon Group (Vail et at., 1977), are not easily identifiable. Therefore, stratigraphic informations are mainly extracted from seismic attribute maps of each sequence or systems tracts, and isopach maps in correlation with the stratigraphic information from the wells. The attribute maps of the sequence or systems tract boundaries and isopach map describe the variations of paleodepositional environments. The shape of the attribute maps of the boundaries is a reasonable description of the shape of the paleodepositional surface. With other maps such as isopach and structural maps, the variations of the parasequences in the systems tracts can be projected using the surface attribute maps. The reflection intensity attribute at each sequence or system tract boundary can be related to lithology, facies or porosity distributions. The azimuth attribute of source rock sequence can be used to identify the hydrocarbon migration patterns into the prospects. The overall risks of reservoir rocks, cap rocks, structure and hydrocarbon migrations were computed using the results of the study.

• Journal of Life Science
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• v.7 no.3
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• pp.198-204
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• 1997

The signal transduction through tyrosine kinases play important roles in neuronal development and synaptic regulation. We carried out immunoblot analyses to study tyrosine=phosphorylated proteins in the rat cerebellar postsynaptic density (PSD), a protein-rich cytoskeletal specialization underlying beneath the postsynaptic membrane. The overall protein composition of cerebellar PSD fractions was similar to that of the forebrain’s and only a few bands were different in Coomassie stain. Immunoblot analyses with phosphtyrosine-specific antiboy (4G10) showed that there are many more tyrosine-phosphorylated proteins in the cerebellar PSD than in the forebrain PSD. Interestiingly, a major phosphotyrosine signals in cerebellar PSD fractions was associated with a 50 kD molecular size, named as PSD-50. Migration of PSD-50 coincided with that of $\alpha$CaMKII and remained in the pellet fraction after N-octylglucoside extraction. These results indicate that tyrosine phosphorylation is important in cerebellar synaptic regulation and that the PSD-50 may be same as $\alpha$CaMKIIor a new protein which is a major substrate of tyrosine kinase.

• International Journal of Oral Biology
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• v.46 no.3
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• pp.105-110
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• 2021

The physicochemical properties of crystalline titanium dioxide nanoparticles (TiO₂ NPs) were investigated by comparing amorphous (amTiO₂), anatase (aTiO₂), metaphase of anatase-rutile (arTiO₂), and rutile (rTiO₂) NPs, which were prepared at various calcination temperatures (100℃, 400℃, 600℃, and 900℃). X-ray diffraction (XRD) and scanning electron microscopy (SEM) analyses confirmed that the phase-transformed TiO₂ had the characteristic features of crystallinity and average size. The surface chemical properties of the crystalline phases were different in the spectral analysis. As anatase transformed to the rutile phase, the band of the hydroxyl group at 3,600-3,100 cm^-1 decreased gradually, as assessed using Fourier transform infrared spectroscopy (FT-IR). For ultraviolet-visible (UV-Vis) spectra, the maximum absorbance of anatase TiO₂ NPs at 309 nm was blue-shifted to 290 nm at the rutile phase with reduced absorbance. Under the electric field of capillary electrophoresis (CE), TiO₂ NPs in anatase migrated and detected as a broaden peak, whereas the rutile NPs did not. In addition, anatase showed the highest photocatalytic activity in an UV-irradiated dye degradation assay in the following order: aTiO₂ > arTiO₂ > rTiO₂. Overall, the phases of TiO₂ NPs showed characteristic physicochemical properties regarding size, surface chemical properties, UV absorbance, CE migration, and photocatalytic activity.

• Journal of the Korea Fashion and Costume Design Association
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• v.21 no.3
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• pp.1-11
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• 2019

This study examined the cause of the phenomenon of shrinkage in machine-embroidered fabrics, specifically those made of thin and pliable fabrics. Four woven fabrics and two knitted fabrics were selected as samples for analysis. The fabrics selected were silk organza, flax linen, polyester chiffon, cotton batiste, polyester raschel mesh, and cotton jersey. The thickness and drapability of the fabrics were observed and the shrinkage of the various types of embroidered fabrics produced using satin & step stitch techniques were measured. Moreover, the correlation between the shrinkage of the machine-embroidered fabrics and the drapability of the original fabrics was analyzed. Also, the colorfastness of six embroidery yarns was determined. The results of the study are as follows: first, the shrinkage of machine-embroidered fabrics increased at a greater rate than in embroidered knitted fabrics as compared to rates in embroidered woven fabrics. Moreover, in terms of stitch techniques, there was a greater shrinkage rate when satin stitch was applied compared to step stitch. Second, the shrinkage rate of machine-embroidered fabrics decreased when a stabilizer was fused onto the fabric. The shrinkage rate also decreased for fabrics when fused with paper stabilizer compared to those without it, and the rate decreased at a greater amount with paper stabilizer as compared to alginate film. Third, since there was a strong correlation between the shrinkage rate of the embroidered fabric and the drapability ratio of the original fabric, it was generally the case that the more pliable the fabric was, the greater the shrinkage rate was when the fabric was embroidered. Fourth, while the embroidery yarns mainly used in machine-embroidery presented an overall excellent level of colorfastness, there was slight color migration of level 4 to level 5 when using viscose rayon.

• Biomolecules & Therapeutics
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• v.27 no.2
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• pp.216-221
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• 2019

The c-Met protein is a receptor tyrosine kinase involved in cell growth, proliferation, survival, and angiogenesis of several human tumors. Overexpression of c-Met has been found in gastric cancers and correlated with a poor prognosis. Indirubin is the active component of Danggui Longhui Wan, which is a traditional Chinese antileukemic recipe. In the present study, we tested the anti-cancer effects of an indirubin derivative, LDD-1937, on human gastric cancer cells SNU-638. When we performed the in vitro kinase assay against the c-Met activity, LDD-1937 inhibited the activity of c-Met. This result was confirmed by immunoblot and immunofluorescence of phosphorylated c-Met. Immunoblot analysis showed that LDD-1937 decreased the expression of the Erk1/2, STAT3, STAT5, and Akt, downstream proteins of c-Met. In addition, LDD-1937 reduced the cell viability and suppressed colony formation and migration of SNU-638 cells. Furthermore, LDD-1937 induced $G_2/M$ phase arrest in the SNU-638 cells by decreasing the expression levels of cyclin B1 and CDC2. Cleaved-PARP, an apoptosis-related protein, was up-regulated in cells treated with LDD-1937. Overall, this study suggests that LDD-1937 may be a novel small-molecule with therapeutic potential for selectively inhibiting c-Met and c-Met downstream pathways in human gastric cancers overexpressing c-Met.

• Journal of Environmental Science International
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• v.30 no.12
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• pp.1067-1079
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• 2021

The coastal water is a space where salmon (Oncorhynchus keta), critical energy-conveying mediator, stay to adapt to different environments while traveling between ocean and river ecosystems for spawning and growth. The mid-eastern coast of Korea (MECW) is the southern limit of salmon distributed in the North Pacific Ocean. Understanding the distribution and migration characteristics of salmon in the MECW is important for the prediction of changes in the amount and distribution of salmon related to changes in the future marine environment. We analyzed the relationship between the salmon migratory timing ascending the Wangpi river and change in vertical seawater temperature and tidal elevation. Overall results highlight that (1) Salmon began to ascend the river when the sea surface water temperature (SST) decreased below 20℃; (2) The number of salmon ascending the river increased when the temperature difference between the upper and lower layers decreased, but decreased when the temperature difference was higher than 5℃; (3) The number of salmon ascending the river peaked, when the SST was 18℃-19℃ and sea levels rose at high tide. This study provide important insight into predicting changes in the ecosystem energy circulation through climate change at its southern distribution limit.