• The Journal of the Korea Contents Association
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• v.10 no.2
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• pp.258-267
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• 2010

This interest in radiation exposure makes increasing doctor's awareness and knowledge of radiation dose in patients during X-ray test important in reducing patient's uneasiness. However, very few facilities are equipped with measurement instruments. Therefore, an intensive study to find out patient dose using computational method has been initiated. This study used special features of the bit system and NDD-M and directly measured the output dose of diagnostic X-ray instruments used in Korea to create tables. Two different methods were found to be adequate when applied to cases when X-ray outputs were both known and unknown, and comparative experiments with real measurement doses were carried out. Presented methods were found to provide more accurate results compared to the bit system and NDD-M. Therefore, patient dose during clinical trials were found to be more easily acceptable to medical personnel in the radiation field in terms of radiation exposure and reduction of medical X ray dose.

• 한국생물공학회:학술대회논문집
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• 2000.11a
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• pp.187-190
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• 2000

Effects of gamma ionizing radiation on recombinant Escherichia coli cells containing stress promoters, recA, fabA, grpE, or katG, fused to luxCDABE originated from Vibrio fischeri were characterized by monitoring transcriptional responses reflected by bioluminescent output. Quantification of gamma-ray intensity may be possible using the recA and fabA promoter fusion since a linear enhancement of bioluminescence emission with increasing gamma-ray intensity was observed. Other strains sensitive to either oxidative stress (DPD2511, katG::luxCDABE) or protein-damaging stress (TV1061, grpE::luxCDABE) were also irradiated by gamma-rays, and resulted in no noticeable bioluminescent output while DPD2794 with recA promoter and DPD2540 with fabA promoter irradiated by the same intensities of gamma-rays gave a significant bioluminescent output. This indicates that the main stresses in the recombinant bacteria caused by ionizing radiation are DNA and membrane-damage, not protein- or oxidative-damage. In addition, in this study, to investigate the relationship between the radiation dose rate and bacterial responses, two recombinant Escherichia coli strains, DPD2794 and GC2, containing lac promoter fused to luxCDABE originating from Photorhapdus luminescences, were used for detecting DNA damage and cellular toxicity under various radiation dose rates. Throughout this study, it was found that these bacteria showed quantitative stress responses to DNA damage and general toxicity caused by gamma rays, depending on the radiation dose rates, indicating that the bacterial stress responses and general toxicity were seriously influenced according to radiation dose rates.

• Journal of Biomedical Engineering Research
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• v.34 no.2
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• pp.73-79
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• 2013

Purpose: The purposes of this study were to measure the dose distribution of Photodynamic therapy(PDT) laser with 635 nm wavelength using GafChromic film. Method & Result: We made each output 300 J by changing mW and sec using the laser beam radiation mode such as C.W(Continuous Wave) mode, Pulse mode and Burst Pulse mode and measured the does at 0 mm and 5 mm of distance from optic fiber catheter end to the film, and at 5 mm distance by changing the angle of the end of the optic fiber catheter as $0^{\circ}$ and $0.5^{\circ}$. The radiated film was scanned and OD(Optical Density) was compared. And two-dimensional isodose curves were obtained and the consistency of shapes was compared. It was confirmed that there was consistency between optic density and the dose radiated on the film when we radiated GafChromic film by changing distance and angle of 300 J output in each radiation mode coordinating mW and sec. Conclusion: In this study, we could identify the stability according to changes in laser beam modes, changes in output according to distance, changes in uniformity according to angle, and beam profiles using GafChromic film, and we could also get two-dimensional isodose curve. It was found that small change in the distance and angle that is made when optic fiber catheter was contacted on the treatment area did not make big effects on the output of beam and the uniformity of dose, and it was also found that GafChromic film could be utilized for the purpose of QA of PDT laser beam.

• The Journal of Korean Society for Radiation Therapy
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• v.31 no.1
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• pp.17-24
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• 2019

Purpose: The present study aims to assess the level of coherency and the accuracy of Point dose of the Isocenter of VERO, a linear accelerator developed for the purpose of the Stereotactic Body Radiation Therapy(SBRT). Materials and Method: The study was conducted randomly with 10 treatment plans among SBRT patients in Kyungpook National University Chilgok Hospital, using VERO, a linear accelerator between June and December, 2018. In order to assess the equipment's power stability level, we measured the output constancy by using PTW-LinaCheck, an output detector. We also attempted to measure the level of accuracy of the equipment's Laser, kV(Kilo Voltage) imaging System, and MV(Mega Voltage) Beam by using Tofu Phantom(BrainLab, Germany) to assess the accuracy level of geometrical Isocenter. We conducted a comparative analysis to assess the accuracy level of the dose by using an acrylic Phantom($30{\times}30{\times}20cm$), a calibrated ion chamber CC-01(IBA Dosimetry), and an Electrometer(IBA, Dosimetry). Results: The output uniformity of VERO was calculated to be 0.66 %. As for geometrical Isocenter accuracy, we analyzed the error values of ball Isocenter of inner Phantom, and the results showed a maximum of 0.4 mm, a minimum of 0.0 mm, and an average of 0.28 mm on X-axis, and a maximum of -0.4 mm, a minimum of 0.0 mm, and an average of -0.24 mm on Y-axis. A comparison and evaluation of the treatment plan dose with the actual measured dose resulted in a maximum of 0.97 % and a minimum of 0.08 %. Conclusion: The equipment's average output dose was calculated to be 0.66 %, meeting the ${\pm}3%$ tolerance, which was considered as a much uniform fashion. As for the accuracy assessment of the geometric Isocenter, the results met the recommended criteria of ${\pm}1mm$ tolerance, affirming a high level of reproducibility of the patient's posture. The difference between the treatment plan dose and the actual measurement dose was calculated to be 0.52 % on average, significantly less than the 3 % tolerance, confirming that it obtained predicted does. The current study suggested that VERO equipment is suitable for SBRT, and would result in notable therapeutic effect.

• Progress in Medical Physics
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• v.12 no.1
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• pp.19-29
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• 2001

In dose modeling, the shape of actual source and sealed capsule are important parameter to determine the physical dose computation. The author investigated the effect of filter of source self-absorption and sealed capsule to designed the high dose rate Ir-192 source for Ralstron(Japan) unit. The size of source designed to 1.5 mm $\Phi$ x 1.5mm length of actual source sealed with stainless steel which is 3.0mm $\Phi$ x 12.0mm length connected to driving cable. The dose attenuation was derived 66.3 % from 2655 segmented source at reference point of 10mm lateral distance of source. The output dose rate factor in tissue for designed source showed 0.0013511 cGy/mCi-sec in reference point at 1cm lateral distance of source center. The dose distribution at inferior of source showed the 52% of that of source tip region, however, the filtering effect was small as 4% at 45degrees of source axis. The dose attenuation within 20 degrees of source axis at near source-cable connector showed large filtering effect as 40% over, but the small effect was revealed isotropic dose distribution at large angle.

• Proceedings of the KOSOMBE Conference
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• v.1996 no.11
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• pp.15-17
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• 1996

In this paper, the therapy radiation dose measurement system has been implemented by using a microcomputer after radiation was irradiated on diodes from the MM22 microtron accelerator. We have displayed 7-channel diode output values on the LCD after processing those in the 80196 MCU(Micro Computer Unit). Signal processing has been performed in the pulse mode because we can process the signal fast and use it to perform portal image by increasing a number of diode channels in the future. In order to verify the microcomputer based radiation measurement system of diodes, diode output values were compared with that of semiconductor.

• Korean Journal of Digital Imaging in Medicine
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• v.13 no.1
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• pp.27-32
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• 2011

The conventional types of X-ray generators were bulky in physical size and heavy in weight, and the control accuracies of the output voltages were not always satisfactory. The high frequency switching inverter and converter technology on power conversion and control systems have been greatly closed up introducing power semiconductor devices. To decreasing the volume and the weight of high voltage transformer, and to stabilize ripple. In this paper, the newly developed x-ray generator in a low cost using duty modulation PWM inverter. This system verify improved performance by stabilize ripple of X-ray tube voltage and compared the reproducibility, linearity and dose in single phase, three phase and PSU.

• Current Photovoltaic Research
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• v.6 no.3
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• pp.81-85
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• 2018

The photovoltaic modules installed in the actual field are affected by various external environments and the electrical performance output value is generally lowered compared to initial output value. The most of photovoltaic modules consists of low iron glass, encapsulant (EVA), back sheet, frame and junction box assembly based on the solar cells. In this paper, the characteristics of encapsulant which is an important constituent material of photovoltaic module were verified by maximum power determination, electro luminescence images, yellowness index measurement, and gel content measurement after ultraviolet (UV) irradiation exposure. The most commonly installed 72 cells crystalline photovoltaic modules were tested after various UV exposure of 0, 15, 30, and $60kWh/m^2$ and compared with the reference module. After UV exposure of $15kWh/m^2$, which is the current international test condition, a small amount of change was observed in yellowness index and electroluminescence, while a gell content rapidly increased. At a cumulative dose of $60kWh/m^2$, which will be a new international test condition in the near future, however, the yellowness index increased sharply and showed the greatest output power drop.

• Journal of radiological science and technology
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• v.43 no.2
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• pp.105-114
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• 2020

This study aimed to assess of beam-matching accuracy for an 8 MV beam between the same model linear accelerators(Linac) commissioned over two years. Two models were got the customer acceptance procedure(CAP) criteria. For commissioning data for beam-matched linacs, the percentage depth doses(PDDs), beam profiles, output factors, multi-leaf collimator(MLC) leaf transmission factors, and the dosimetric leaf gap(DLG) were compared. In addition, the accuracy of beam matching was verified at phantom and patient levels. At phantom level, the point doses specified in TG-53 and TG-119 were compared to evaluate the accuracy of beam modelling. At patient level, the dose volume histogram(DVH) parameters and the delivery accuracy are evaluated on volumetric modulated arc therapy(VMAT) plan for 40 patients that included 20 lung and 20 brain cases. Ionization depth curve and dose profiles obtained in CAP showed a good level for beam matching between both Linacs. The variations in commissioning beam data, such as PDDs, beam profiles, output factors, TF, and DLG were all less than 1%. For the treatment plans of brain tumor and lung cancer, the average and maximum differences in evaluated DVH parameters for the planning target volume(PTV) and the organs at risk(OARs) were within 0.30% and 1.30%. Furthermore, all gamma passing rates for both beam-matched Linacs were higher than 98% for the 2%/2 mm criteria and 99% for the 2%/3 mm criteria. The overall variations in the beam data, as well as tests at phantom and patient levels remains all within the tolerance (1% difference) of clinical acceptability between beam-matched Linacs. Thus, we found an excellent dosimetric agreement to 8 MV beam characteristics for the same model Linacs.

• Journal of radiological science and technology
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• v.43 no.6
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• pp.431-441
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• 2020

The purpose of this study was to construct a model of MVCT(Megavoltage Computed Tomography) dose calculation by using Dosimetry Check™, a program that radiation treatment dose verification, and establish a protocol that can be accumulated to the radiation treatment dose distribution. We acquired sinogram of MVCT after air scan in Fine, Normal, Coarse mode. Dosimetry Check™(DC) program can analyze only DICOM(Digital Imaging Communications in Medicine) format, however acquired sinogram is dat format. Thus, we made MVCT RC-DICOM format by using acquired sinogram. In addition, we made MVCT RP-DICOM by using principle of generating MLC(Multi-leaf Collimator) control points at half location of pitch in treatment RP-DICOM. The MVCT imaging dose in fine mode was measured by using ionization chamber, and normalized to the MVCT dose calculation model, the MVCT imaging dose of Normal, Coarse mode was calculated by using DC program. As a results, 2.08 cGy was measured by using ionization chamber in Fine mode and normalized based on the measured dose in DC program. After normalization, the result of MVCT dose calculation in Normal, Coarse mode, each mode was calculated 0.957, 0.621 cGy. Finally, the dose resulting from the process for acquisition of MVCT can be accumulated to the treatment dose distribution for dose evaluation. It is believed that this could be contribute clinically to a more realistic dose evaluation. From now on, it is considered that it will be able to provide more accurate and realistic dose information in radiation therapy planning evaluation by using Tomotherapy.