• Journal of Korean Neurosurgical Society
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• v.56 no.3
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• pp.248-253
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• 2014

Objective : Cortical dysplasia (CD) is one of the common causes of epilepsy surgery. However, surgical outcome still remains poor, especially with frontal lobe epilepsy (FLE), despite the advancement of neuroimaging techniques and expansion of surgical indications. The aim of this study was to focus on surgical strategies in terms of extent of resection to improve surgical outcome in the cases of FLE with CD. Methods : A total of 11 patients of FLE were selected among 67 patients who were proven pathologically as CD, out of a total of 726 epilepsy surgery series since 1992. This study categorized surgical groups into three according to the extent of resection : 1) focal corticectomy, 2) regional corticectomy, and 3) partial functional lobectomy, based on the preoperative evaluation, in particular, ictal scalp EEG onset and/or intracranial recordings, and the lesions in high-resolution MRI. Surgical outcome was assessed following Engel's classification system. Results : Focal corticectomy was performed in 5 patients and regional corticectomy in another set of 5 patients. Only 1 patient underwent partial functional lobectomy. Types I and II CD were detected with the same frequency (45.45% each) and postoperative outcome was fully satisfactory (91%). Conclusion : The strategy of epilepsy surgery is to focus on the different characteristics of each individual, considering the extent of real resection, which is based on the focal ictal onset consistent with neuroimaging, especially in the practical point of view of neurosurgery.

• Korea-Australia Rheology Journal
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• v.17 no.3
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• pp.99-110
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• 2005

This work presents results of finite element analysis of isothermal incompressible creeping viscoelastic flows with the tensor-logarithmic formulation of the Leonov model especially for the planar geometry with singular comers in the domain. In the case of 4:1 contraction flow, for all 5 meshes we have obtained solutions over the Deborah number of 100, even though there exists slight decrease of convergence limit as the mesh becomes finer. From this analysis, singular behavior of the comer vortex has been clearly seen and proper interpolation of variables in terms of the logarithmic transformation is demonstrated. Solutions of 4:1:4 contraction/expansion flow are also presented, where there exists 2 singular comers. 5 different types spatial resolutions are also employed, in which convergent solutions are obtained over the Deborah number of 10. Although the convergence limit is rather low in comparison with the result of the contraction flow, the results presented herein seem to be the only numerical outcome available for this flow type. As the flow rate increases, the upstream vortex increases, but the downstream vortex decreases in their size. In addition, peculiar deflection of the streamlines near the exit comer has been found. When the spatial resolution is fine enough and the Deborah number is high, small lip vortex just before the exit comer has been observed. It seems to occur due to abrupt expansion of the elastic liquid through the constriction exit that accompanies sudden relaxation of elastic deformation.

• Journal of Korean Neurosurgical Society
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• v.58 no.3
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• pp.262-270
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• 2015

Objective : Long-term oral anticoagulation or antiplatelet therapy has been used with increasing frequency in the elderly. These patients are at increased risk of morbidity and mortality from expansion of intracranial hemorrhage. We conducted a single-center retrospective case control study to evaluate risk factors associated with outcomes and to identify the differences in outcome in traumatic brain injury between preinjury anticoagulation use and without anticoagulation. Methods : A retrospective study of patients who underwent craniotomy or craniectomy for acute traumatic cerebral hemorrhage, between January 2005 and December 2014 was performed. Results : A consecutive series of 50 patients were evaluated. The factors significantly differed between the two groups were initial Prothrombin Time-International Normalized Ratio, initial platelet count, initial Glasgow Coma Scale score, and postoperative intracranial bleeding. Mean Glasgow Outcome Scale (GOS) score were similar between the two groups. In the patient with low-energy trauma only, no significant differences in GOS score, postoperative bleeding and many other factors were observed. The contributing factors to postoperative bleeding was preinjury anticoagulation and its adjusted odds ratio was 12 [adjusted odds ratio (OR), 12.242; p=0.0070]. The contributing factors to low GOS scores, which mean unfavorable neurological outcomes, were age (adjusted OR, 1.073; p=0.039) and Rotterdam scale score for CT scans (adjusted OR, 3.123; p=0.0020). Conclusion : Preinjury anticoagulation therapy contributed significantly to the occurrence of postoperative bleeding. However, preinjury anticoagulation therapy in the patients with low-energy trauma did not contribute to the poor clinical outcomes or total hospital stay. Careful attention should be given to older patients and severity of hemorrhage on initial brain CT.

• Journal of the Korean Society for Library and Information Science
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• v.37 no.4
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• pp.223-240
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• 2003

The process of managing the results of national R&D projects, which are aimed at strengthening national competitiveness has been ineffective so far. The existing structure for managing the results of national R&D projects have largely been relying on just strong and managing the result of each project and not on the utilization and expansion of the results for further application. We aim at developing a system that would exceed the current system which heavily relies on a passive paradigm of management and circulation of technology. Through the newly developed system, we look forward to achieve the major goals of R&D, such as cutting down the expenses, increasing the margin improving the technology and expanding the influence of the research to other areas from through improving the system as well as the process for managing R&D projects.

• Clinical and Experimental Reproductive Medicine
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• v.38 no.2
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• pp.87-92
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• 2011

Objective: This study aimed to determine the safety and clinical effect of artificial shrinkage (AS) in terms of assisted hatching of fresh blastocysts. Also, we evaluated the correlation between patient age and the effect of AS on clinical outcome. Methods: Two AS methods, using a 29-gauge needle and laser pulse, were compared. Seventy-three blastocysts were shrunk using a 29-gauge needle and the same number of other blastocysts were shrunk by a laser pulse. We evaluated the shrunken blastocysts hourly and considered them viable if they re-expanded >70%. Blastocyst transfer cycles (n=134) were divided into two groups: a control group consisted of the cycles whose intact embryos were transferred (n=100), while the AS group consisted of the cycles whose embryos were replaced following AS (n=34). The implantation and pregnancy rates of the control group and AS group were compared ($p$ <0.05). Results: The re-expansion rates of the 29-gauge needle and laser pulse AS groups were similar (56 [76.7%] vs. 62 [84.9%], respectively). All of the remaining shrunken blastocysts were re-expanded within 2 hours. There was no degeneration of shrunken blastocysts. The total and clinical pregnancy rate of the AS group (23 [67.6%]; 20 [58.8%], respectively) was significantly higher than that of the control group (47 [47.0%]; 39 [39.0%], respectively). In the older patient group, there was no difference in the clinical outcomes between the AS and control groups. Conclusion: These results suggest that AS of blastocoele cavity, followed by the transfer, would be a useful approach to improve the clinical outcome in cycles in which fresh blastocyst stage embryos are transferred.

• Clinical and Experimental Reproductive Medicine
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• v.43 no.1
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• pp.31-37
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• 2016

Objective: The aim of this study was to investigate associations between the morphology score of blastocysts and blastocoele re-expansion speed after warming with clinical outcomes, which could assist in making correct and cost-effective decisions regarding the appropriate time to vitrify blastocysts and to transfer vitrified-warmed blastocysts. Methods: A total of 327 vitrified-warmed two-blastocyst transfer cycles in women 38 years old and younger were included in this retrospective study. Results: The clinical pregnancy rate (CPR) and implantation rate (IR) of transfers of two good-morphology grade 4 blastocysts vitrified on day 5 (64.1% and 46.8%, respectively) were significantly higher than the CPR and IR associated with the transfers of two good-morphology grade 3 blastocysts vitrified on day 5 (46.7% and 32.2%, respectively). No significant differences were found in the CPR and IR among the transfers of two good-morphology grade 4 blastocysts regardless of the day of cryopreservation. Logistic regression analysis showed that blastocoele reexpansion speed after warming was associated with the CPR. Conclusion: The selection of a good-morphology grade 4 blastocyst to be vitrified could be superior to the choice of a grade 3 blastocyst. Extending the culture of grade 3 blastocysts and freezing grade 4 or higher blastocysts on day 6 could lead to a greater likelihood of pregnancy. Since re-expansion was shown to be a morphological marker of superior blastocyst viability, blastocysts that quickly re-expand after warming should be prioritized for transfer.

• The Journal of Korean Physical Therapy
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• v.27 no.3
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• pp.147-153
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• 2015

Purpose: The purpose was to determine whether the application of the abdominal drawing-in maneuver (ADIM) and abdominal expansion maneuver (AEM) to stroke patients would affects their trunk stability, balance, pulmonary function, and grip strength. Methods: The subjects were 36 stroke patients who were randomly and equally assigned to an ADIM group (n=12), an AEM group (n=12), and a control group (n=12). The intervention was applied to each group three times per week, 30 minutes each time, for four weeks. Outcome measures were grip strength, modified functional reach test (mFRT) and pulmonary function. Pulmonary function were measured force expiratory volume at one second (FEV1), forced vital capacity (FVC), FEV1/FVC and peak expiratory flow (PEF) values. Results: The results of the three groups showed statistically significant improvements in grip strength. The AEM group showed significantly greater differences in grip strength than either the ADIM group or the control group. In the anterior mFRT, the ADIM group showed significantly improvements than the control group. The ADIM and AEM groups were showed statistically significant greater improvements in PEF between the baseline and post-intervention and the post-analysis revealed that the AEM group showed significantly greater improvements than the control group. Conclusion: The results of this study indicate that the ADIM and AEM were effective in improving the PEF of pulmonary function. The ADIM was more effective than AEM in trunk stabilization.

• Management & Information Systems Review
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• v.9
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• pp.165-177
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• 2002

The purpose of this comparative study is to compare and evaluate international arbitration and forum selection agreements. Recent decades have seen an unparalleled expansion of global trade and investment. Business enterprises of every description ann find themselves entangled in legal proceedings with foreign companies or government entities. Thus, the costs of these proceedings and the consequences of losing are often substantial. Almost, every international commercial controversy poses a critical preliminary question - 'where, and by whom, will this dispute be decided?' the answer to this question often decisively affects a dispute's eventual outcome. It can mean the difference between winning and losing. between de minimis damages and a multimillion dollar award. The same dispute can have materially different outcomes in different forums. Because of the importance of forum selection, parties to international contracts often include contractual dispute resolution provisions in their agreements. These provisions significantly reduce the uncertainties inherent in international commercial disputes, and can offer a substantial measure of partisan advantage. as a consequence, it is almost always advisable to include a contractual dispute resolution provision in any international contract. These provisions typically take the form of : (1) forum selection clauses, or (2) arbitration agreements.

• Journal of the Korean Ceramic Society
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• v.44 no.2 s.297
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• pp.79-83
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• 2007

To fabricate a thick, porous yttria-stabilized zirconia without cracking and warping, a method for the simultaneous control of the porosity and shrinkage was designed. As a pore former, a potato starch was used. For the control of shrinkage the oxidation of Al metal particles was used. For the sintering of the above powder mixtures, a partial sintering technique was used at $1300^{\circ}C$ for 10 min in air. Upon adding the additives, high open porosity above 53% and a low shrinkage level were obtained. As a result cracking and warping of the sintered body were deterred. This outcome most likely resulted from the compensation of sintering shrinkage due to the volume expansion caused by oxidation of the Al metal particles during heat-treatment.

• Proceedings of the KSR Conference
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• 1998.05a
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• pp.137-159
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• 1998

For the construction of railroads in Metropolytan area based upon the outcome of the future demand forecast, a total of 21 lines including electrified double track segment of Ui-Jung-Bu↔Dong-Du-Chun(18.9km) in Kyung-Won Line is expected. Considering the financial difficulties and investment effect of the lines, this in the sequel brings about an important matter of deforming priority Investment plan to build electrified lines among the candidates. In the case of Japan, Tokyo metropolytan area covered In total by 2,070.1km of various lines, i.e., subway lines(241km), private lines(952.7km), JR lines(876.4km), provides convenient means of transportation for the coummuters and makes a contribution to the development of its neighboring areas and to the expansion of settlement areas. Comparing the total length per 1,000$\textrm{km}^2$, Tokyo(105), Paris(117), and London(115) are at least 6 times as large as ours(15). The purpose of this study is two fold provide a basic scheme for building railroads in metropolytan area and determine priority order in accordance with some evaluation criteria.