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DNA 염기 서열의 단편 조립 프로그램 개발

  • Lee, Byung-Uk;Park, Kie-Jung;Park, Wan;Park, Yong-Ha
    • Microbiology and Biotechnology Letters
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    • v.25 no.6
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    • pp.560-565
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    • 1997
  • DNA fragment assembly is a major concem in shot-gun DNA sequencing project. It is to reconstruct a consensus DNA sequence from a collection of random oritented fragments. We developed a computer program that is useful for DNA fragment assembly. Inputs to the program are DNA fragment sequences including IUB-IUPAC bases. The program produces the most probable reconstruction ot the original DNA sequence as a text format or a PostScript format. The program consists of four phases: the first phase quickly eliminates fragment pairs that can not possibly overlap. In the second phase, the quality of overlap between each pair is calculated to a score. In the third phase, overlap pairs are sorted by their scores and consistency of the overlaps is checked. The last phase determines consensus sequences and displays them. The performance of fragment assembly program was tested on a set of DNA fragment sequences which were generated from long DNA sequences of GenBank by a fragmentation program.

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Implementation of Rank/Select Data Structure using Alphabet Frequency (문자의 빈도수를 고려한 Rank/Select 자료구조 구현)

  • Kwon, Yoo-Jin;Lee, Sun-Ho;Park, Kun-Soo
    • Journal of KIISE:Computer Systems and Theory
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    • v.36 no.4
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    • pp.283-290
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    • 2009
  • The rank/select data structure is a basic tool of succinct representations for several data structures such as trees, graphs and text indexes. For a given string sequence, it is used to answer the occurrence of characters up to a certain position. In previous studies, theoretical rank/select data structures were proposed, but they didn't support practical operational time and space. In this paper, we propose a simple solution for implementing rank/select data structures efficiently. According to experiments, our methods without complex encodings achieve nH$_0$ + O(n) bits of theoretical size and perform rank/select operations faster than the original HSS data structure.

Design and Implementation of Self-networking and Replaceable Structure in Mobile Vector Graphics

  • Jeong Gu-Min;Na Seung-Won;Jung Doo-Hee;Lee Yang-Sun
    • Journal of Korea Multimedia Society
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    • v.8 no.6
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    • pp.827-835
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    • 2005
  • In this paper, self-networking and replaceable structure in vector graphics contents are presented for wireless internet service. The wireless networks over 2G or 3G are limited in the sense of the speed and the cost. Considering these characteristics of wireless network, self-networking method and replaceable structure in downloaded contents are introduced in order to save the amount of data and provide variations for contents. During the display of contents, a certain data for the contents is downloaded from the server and it is managed appropriately for the operation of the contents. The downloaded materials are reflected to the original contents using replaceable structure. Also, the downloading and modification are independent of the play. In this implementation, the data consists of control data for control and resource data for image, sound or text. Comparing to the conventional methods which download the whole data, the amount of the transmitted data is very small since only the difference is downloaded. Also, during the play of the contents, the changes are adopted immediately. The whole functions are implemented in wireless handset and the various applications are discussed.

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Social Annotation and Navigation Support for Electronic Textbooks (전자책 환경을 위한 사회적 어노테이션 및 탐색 지원 기법)

  • Kim, Jae-Kyung;Sohn, Won-Sung
    • Journal of Korea Multimedia Society
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    • v.12 no.10
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    • pp.1486-1498
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    • 2009
  • Modem efforts on digitizing electronic books focus on preserving authentic image representation of the original sources. Unlike the text-based format, it is difficult to recognize the information in the image, so the new format requires new tools to help users to access, process, and make sense of digital information. This paper presents an approach which assists users of these image sources by giving them a combination of annotation and social navigation support. Especially in the education domain, the proposed technique improves the usability of online education system. This approach is currently fully implemented and under evaluation in a classroom study.

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A Structure of Generating the Fan-made Works in Korean Idol (한국 아이돌 팬 창작물의 생성 구조)

  • Chung, Eun-hye;Han, Hye-won
    • The Journal of the Korea Contents Association
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    • v.20 no.9
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    • pp.158-168
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    • 2020
  • This paper analyzed the process of text generation of the fan-made works in Korean idol. The subjects of the study adopted the fan-made works of 'BTS' and 'EXO'. This is applied the concepts of 'Apparatus-Operator' and 'Technical form' in Vilém Flusser. Idol contents build a database of fan-made works and create the storyworld through separation and integration of fan's interpretations. By decontextualizing and recontextualizing the idol contents, fans reinforce and extend the original texts.

Induced apoptosis in human Uterine Leiomyoma Cells by treatment with Chiljehyangbu-hwan (칠제향부환(七製香附丸)이 자궁근종세포의 성장억제와 세포자멸사에 미치는 영향)

  • Kim, Seuk-Jung;Beak, Seung-Hee;Kim, En-Ha;Kim, Dong-Chul
    • The Journal of Korean Obstetrics and Gynecology
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    • v.20 no.2
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    • pp.25-42
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    • 2007
  • Purpose : Uterine leiomyoma (fibroids) are benign smooth muscle tumors originating from the myometrium. These benign neoplasms of monoclonal origin are typically diagnosed during the reproductive years, occurring only after puberty and tending to regress after menopause. In the present study we used Chiljehyangbu-hwan to determine its growth inhibitory effect and apoptosis in human uterine leiomyoma cells. Methods : Primary cultured human uterine leiomyoma cells were treated with Chiljehyangbu-hwan. Cell viability analysis was analyzed by MTS assay and FACS was performed to ascertain the effects Chiljehyangbu-hwan. DNA fragmentation analysis and casapase-3 activity test were done. Expression of apoptosis related proteins were evaluated by Western blot analysis. Results : Cell viability was significantly influenced by Chiljehyangbu-hwan treatment in a dose-dependent manner in leiomyoma cells compare to normal myometrial cells. FACS showed that Chiljehyangbu-hwan induced Sub G1 arrest. DNA fragmentation assay was carried out and apoptosis was detected. Activation of caspase-3, down-regulation of Bcl-2, with concomitant increased expression in Bid and Bax were observed. Chiljehyangbu-hwan treatment of uterine leiomyoma cells resulted in a concentration-dependent cell death induced via the mitochondrial pathway.

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The Problems and Solutions in the Pilot Test of Electronic Bill of Lading (전자선화증권의 운용실증실험상의 문제점과 해결방안)

  • Choi, Seok-Beom
    • International Commerce and Information Review
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    • v.6 no.3
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    • pp.321-349
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    • 2004
  • Bolero Project initially had the support of TEDIS, and now is a joint-venture between SWIFT and IT Club. After the successful testing of an original pilot project, The Bolero Association was formed in 1995 by a group of interested cross industry companies. A Bolero Bill of Lading replicates the basic functions of a paper-based bill of lading via title registry service and core messaging platform. A Bolero Bill of Lading consists of BBL Text and Title Registry Record. A Tittle Registry Record carries out the function of a document of title and a BBL may be transferred by changing the roles of users in this Title Registry Record. TEDI Project had been conducted from the April 1999 to the September 2000 on the basis of the EDEN Project(Dec.97- Mar. 1999) and International Trade Guidances Project (Nov. 1998-Mar. 1999). Through TEDI Project, the RSP Model was introduced as e-trade solution like Bolero's Solution. The RSP Model Solution will be furnished through TC (Trade Chain) Server and RSP(Repository Service Provider) Server. The purpose of this paper is to study the problems and solutions in the pilot test of electronic Bill of Lading using TEDI's RSP and to promote the introduction of electronic Bill of Lading.

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A Study on the Recent Amendment relating to the International Convention for the Prevention of Pollution from Ship, 1973/1978 (73/78 해양오염방지협약의 개정동향과 개요)

  • 황석갑
    • Journal of the Korean Institute of Navigation
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    • v.17 no.2
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    • pp.29-56
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    • 1993
  • The International Convention for the Prevention of Pollution from Ship, 1973, as modified by the Proto-col of 1978 relating thereto, well known as MARPOL 73/78, is probably the most important international agreement on the subject of marine pollution. The main purpose of the Convention is to reduce the total oil remaining on board vessel to minimum. MARPOL is a combination of different sets of rules on oil, chemicals, noxious substances in package forms, sewage and garbage as shown on each Annex. Since the Convention has globally set forth in 1973, it has amended so often whenever reasonable articles are requi-red by contracting states under guidelines of IMO. The amendments, for instance, have continuously perfo-rmed more than 8 times regarding articles, protocols, and five annexes because the original text was badly drafted as the control measures were expressed in general way. This paper, therefore, is intend to summa-rize a main point relating to each amendment, so that persons who have an interest in the Convention would be completely understand for practical implementation. Especially, for legislative purpose or annen-dement of domestic law, it could timely be contributable if specific consolidation and unified interpretations are followed with this paper. Consequently it is much more worth to study for preventing marine pollution from ship with tracing every moment whenever the Convention formally adopted through amending up-to-data.

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The Study on Transformation of the First and the Second Carved Tripitaka on the Basis of the Analysis of Koryokukshinjodaechangkyochongbyollock (고려국신조대장교정별록의 분석을 통해 본 초조 및 재조대장경의 변용에 관한 연구)

  • 강순애
    • Journal of the Korean BIBLIA Society for library and Information Science
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    • v.7 no.1
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    • pp.103-146
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    • 1994
  • Koryokukshinjodaechangkyochongbyollock is an epoch-making catalogue for historical study of proofing Buddhist scriptures in Korea. This bibliography was appended to the 30 volumes which was corrected in 70 Ham, 66 scriptures, and 79 cases. Comparing the differences between the first carved Tripitaka' s texts in Korea, texts made in the Sung dynasty, and the Kitan's texts, this catalogue discovered the name of scriptures, translators, volume number, the changed am order as well as omission, defaults, mistranslation of the Tripitaka made in the Sung dynasty. From Chon-ham to Young-ham, 480 sets among Kaewon-sokkyorock and 43 sets among Chongwonrock were correctly laid. Songshinyokkyong and the Sung Emperor, T'ai Tsung's statements were excluded. Even though it was possible to get these scriptures only by import from Sung, these imported scriptures had no reason to be proofed because of their new version and the author's direct selection in Sung. Shinchipchangkyon-geumeuisuhamlock has no authentic Sung's and Koryo's text books for correction. kyochongbyollock delivered the scriptures listed on Kudaechangmoklock, which gives an important clue to research transformation from the first to the second carved Tripitaka. Through the systematic study of the transformated facts beteween the first carved Tripitaka and the second one, This study would help rebulid the original Chojodaechan-gkynng which has been not yet perfectly discovered itself.

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Epilogue to the unabridged Korean translation of On War ("전쟁론" 완역 후기)

  • Kim, Man-Su
    • Journal of National Security and Military Science
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    • s.7
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    • pp.305-331
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    • 2009
  • This year I published a Korean translation of On War in three volumes, written by Prussian general Carl von Clausewitz. I believe it is the first unabridged Korean translation from the original German text, Vom Kriege. It is true that the work has been translated into Korean several times, but some translations have been done from English or Japanese versions, while others are abridged ones. It is not easy to make a good translation of On War, partly because the book is actually an unfinished work, and partly because it contains almost all academic subjects in social sciences. Moreover, two aspects of the dialectical logic in the book make it more difficult to understand. One is inductive reasoning, the other is deductive explanation. The former is to 'ascend' to draw principles and generalizations from empirical experience, the latter is to 'descend' to describe and explain given principles, often by concrete examples. Considering these difficulties, if we want to have better translations than existing ones, there should be substantial commentaries which contain not only history of wars, but also biographies and geographies concerned. I hope that On War can be taught and studied in many universities, for it will make it easier to produce reliable commentaries.

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