• The Journal of Korean Obstetrics and Gynecology
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• v.20 no.3
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• pp.229-237
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• 2007

Purpose: The purpose of this study was to report the clinical application of traditional korean medicine(TKM) treatment to hyeolheopungyeol type of dermatoses gravidarum. Methods: We experienced four patients who had been suffering from itching, plaque, erythema during pregnancy. They had already been treated with antihistamine or ointment, but they were not improved. We diagnosed their case as hyeolheopungyeol type of dermatoses gravidarum, and treated with sopungsan-gaml. Results: After TKM treatment, itching, plaque and erythema were alleviated or resolved. And they gave birth to a healthy baby. Conclusion: The results indicate that TKM, sopungsan-gami can be effective for the management of hyeolheopungyeol type of dermatoses gravidarum.

• The Journal of Korean Obstetrics and Gynecology
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• v.21 no.2
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• pp.284-291
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• 2008

Purpose: The purpose of this study is to report the effect of oriental treatments for PCOD(Polycystic Ovarian Disease) patient with amenorrhoea. Methods: A 24 years old women, who diagnosed PCOD(Polycystic Ovarian Disease), was enrolled in this study. She received oriental treatments such as herbal medicine, acupuncture for 5 months. And we proceeded to checkup female hormone regularly, such as Estrogen, Progesteron, LH, FSH, Prolactin, testosterone. We observed the menstruation period and figure out LH/FSH ratio. Results: 1. We treated PCOD patient with oriental herbal medicine(Changbudodamtang) and acupuncture. 2. PCOD patient restart menstruation regularly. 3. PCOD patient's LH/FSH ratio decreased. 4. PCOD patient's testosterone was within normal limit. Conclusion: 1. We treated PCOD patient with oriental herbal medicine(Changbudodamtang) and acupuncture, and then PCOD patient restart menstruation regularly. 2. We treated PCOD patient with oriental herbal medicine(Changbudodamtang) and acupuncture, and then we observed that LH/FSH ratio decreased.

• The Journal of Korean Obstetrics and Gynecology
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• v.25 no.1
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• pp.70-78
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• 2012

Objectives: The purpose of this article is not until to investigate the changes and types of statistical methods and to point out the statistical errors after analyzing the method of articles that improve the quality of the statistical analysis of papers published in the Journal of Oriental Obstetrics and Gynecology. Methods: Papers published in the Journal of Oriental Obstetrics and Gynecology from 2009 to 2011 were reviewed for methodological and statistical validity using a modified version of Ahn's checklist. A statistician reviewed individual papers and evaluated the list items in the checklist for each paper. To avoid the potential assessment error by the statistician who lacks expertise in the field of Oriental Obstetrics and Gynecology. Results: A total of 190 papers including 64 original articles, 40 reviews article, 58 case report and 28 brief communication were reviewed. Statistics methods used in 121 papers were composed of t-test(58.7%), ANOVA test(19.8%) and ${\chi}^2$- test (14.0%) et al. Whereas only 14.9% of papers were free of statistical errors, the number of omission errors was 58 and the number of commission errors was 149 each. Conclusions: A variety of statistical errors were encountered in papers published in the Journal of Oriental Obstetrics and Gynecology. Accordingly, researchers should be more careful when it comes to describing and applying statistical methods.

• The Journal of Korean Obstetrics and Gynecology
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• v.21 no.2
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• pp.252-262
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• 2008

Purpose: This paper is aim to report that menopausal disorder can be effectively diagnosed and treated by referring to the life event stress of patient. Methods: Researchers got a grip on the life event stress of patient by using medical examinations by interview and compared the conditions of patient before and after treatment by using Kupperman's Index. The prescription of the Gamidangguisu-san hap samhap-tang( Jiaweidangguixu-san he sanhetang) and the Gamisoyo-san (Jiaweixiaoyao-san) and the acupuncture therapy and the moxibustion therapy were used for the treatment. Results: The serious musculoskeletal systemic pains, which includes back pain, lumbago, and myalgia, and other menopausal troubles were improved remarkably. Conclusion: The menopausal disorder could be caused by not only the change of hormone but also complex factors of environmental matters which includes social cultural surroundings, mentality etc. Therefore the life event stress could be one of critical factors of menopausal disorder. The diagnosis and treatment considering the life event stress could be effective method to relieve patient's menopausal disorder.

• The Journal of Korean Obstetrics and Gynecology
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• v.24 no.2
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• pp.97-103
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• 2011

Objectives: Recently, high attention has been drawn towards evidence based medicine(EBM). However, there is little follow study after Park's analysis research (2002) in the journal of oriental gynecology. Therefore, there is a need to conduct analyzed research on the topic, due to the increasing interest about EBM. Methods: To analyze the treatises of the journal of oriental gynecology, we examined 56 journals published from 1987 to 2010. we followed the way of Park, classifying treatises into bibliographic, experimental and clinical categories. Results: Analytic research, as a part of clinical treatises, increased rapidly from 2001. As a result, it took 53.3% of whole study in general after 2002 and it reached up to 70.0% in 2004. Most part of clinical treatises until 2002 was about case report of patients, but the amount of clinical trial started to increase since 2003. Case report and case series showed dramatic increase after 2001, and clinical trial started to increase after 2003. As a result, 43.8% of the analyzed research was due to clinical trial by 2009. Conclusions: On the base of this research, quality evaluation of clinical treatises using guality assessment tool is needed for EBM in the part of oriental obstetrics & gynecology.

• The Journal of Korean Obstetrics and Gynecology
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• v.26 no.2
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• pp.17-32
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• 2013

Objectives: The purpose of this study was to investigate whether Lonicera japonica(LJ) could inhibit LPS-induced type I IFN production. Methods: To evaluate inhibitory effect of LJ on type I IFN, we examined type I IFN, IRF-1, 7 and IL-10 production on LPS-induced macrophages using real time RT-PCR. Next, we observed the interaction of type I IFN, IRF-1, 7 and IL-10 using IL-10 neutralizing antibody. Finally we examined the activation of STAT-1, 3 using western blot. Results: LJ inhibited Type I IFN expression of mRNA and increased IL-10 expression of mRNA. Also LJ inhibited the level of IRF-1, 7 mRNA and the nuclear translocation of IRF-3. Further more, LJ reduced the activation of STAT-1, 3 which are involved in continuous secretion of immune cytokines. Blockade of IL-10 action caused a significant reduction of type I IFN and IRF-1, 7 than LPS-induced LJ pretreatment. Conclusions: LJ inhibits LPS-induced production of type I IFN by IL-10. This study may provide a clinical basis for anti-inflammatory properties of LJ.

• The Journal of Korean Obstetrics and Gynecology
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• v.24 no.4
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• pp.85-94
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• 2011

Purpose: Hominis placenta have used widely for women's disease like climacteric syndrome, dysmenorrhea, infertility, but we don't have enough evidence with it. This study is to investigate efficacy and safety of Hominis Placenta on women by investigating papers. Methods: We searched for papers which had Hominis placenta, placental extract associated with women's disease in the Pubmed and Korean journals. Results: 20 papers were found. 15 papers were associated with menopausal disorder. Hominis placenta could have the efficacy on osteoporosis and climacteric syndrome induced by menopause. And each 2 papers were relevant to postpartum symptoms and menses. 1 papers was relevant to pregnancy. Most of studies have shown that Hominis placenta is useful for female disorders. Conclusions: Hominis placenta could be a good treatment for female disorder like climacteric syndrome, dysmenorrhea, infertility. But evidence is not enough with Hominis placenta, so more research will be needed.

• The Journal of Korean Obstetrics and Gynecology
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• v.20 no.2
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• pp.188-195
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• 2007

Purpose: The purpose of this study was to analyze current status of the web-sites dealing with oriental obstetrics & gynecology in the internet, and to evaluate their quality and confidence of health information. Methods: It was selected 54 local sites by searching for such key words as menstrual pain. The evaluation tool consisted of six major classification (Content, Authorship, Purpose, Functionality, Feedback and Privacy). Results: In the evaluation of web-sites, the lowest and the highest scores were 7 and 19 out of 26, and the average score was 13.94. The scores of Purpose, Content, Feedback were higher than the average, but the scores of Authorship, Functionality, Privacy were lower than the average. Conclusion: There is a need to develop a high-quality information about latest, confidence, authorship of documents, and to prevent a exposure of privacy.

• The Journal of Korean Obstetrics and Gynecology
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• v.18 no.3
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• pp.242-249
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• 2005

Purpose : The purpose of this paper is to report the effect of oriental medicine to primary infertility caused by uterus unicornis. Methods : The patient in this case, 30 years-old female was treated with herb medication(Sosihotang, Gyejibokryeonghwan) for one month. Before oriental treatment, she had been diagnosed as primary infertility caused by uterus unicornis in Samsung Cheil Hospital and treated medication and injection for IUI(intrauterine insemination) in 2 times. But she had failed in gestation. Results : After taking herb medication she became pregnant. Conclusion : According to this result, we concluded that herb medication could improve fertility rate. After this paper, further study and clinical approach based on oriental medicine will be needed about infertility caused by uterus unicornis.

• The Journal of Korean Obstetrics and Gynecology
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• v.26 no.2
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• pp.66-87
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• 2013

Objectives: The aim of this study was to review systemically clinical trials on the trends of studies for Complementary and Alternative Medicine in the treatment of female sexual dysfunction and provide basic resource for future treatment and suggestions for improving research methods. Methods: Through medical website 'Pubmed', foreign clinical literatures about female sexual dysfunction were searched and domestic clinical literatures about female sexual dysfunction were searched using internet websites 'National assembly library', 'KISS', 'RISS', 'Korean traditional knowledge portal'. Results: Total 19 literatures were selected from January 2000 to June 2012. 15 foreign literatures were selected through medical website and 4 domestic literatures were chosen using internet websites or hand-searching. 5 literatures were published in 2008 and 13 literatures mentioned about age group of patients. FSFI is most common tool for female sexual dysfunction. 9 of 19 literatures were using Herbal medicine for treatment. 5 literatures were about CBT, 6 literatures were about Biofeedback and other one literatures are about Perineal massage. There were 14 Randomized controlled trials and 5 Non-randomized controlled trials. And randomized controlled trials were relatively low in risk of bias than non-randomized controlled trials. Conclusions: Upon these results, in similar future more clinical trials should be done and accumulate Evidence-based literatures.