• The Journal of Korean Obstetrics and Gynecology
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• v.21 no.3
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• pp.231-244
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• 2008

Purpose: The purpose of this study is to analyze body composition, obesity according to working pattern of working women. The subjects were workers in the automobile manufacturing industry. Methods: The subjects consisted of 514 industrial women workers who had received Korean oriental medicine health examination and submitted questionires about working pattern, during 8 months from April 2005 to November 2005. The body composition was measured by X-scan(Jawon medical, Seoul, Korea). We analyzed the relationship between body composition analysis, obesity and shift pattern with $X^2-test$ using the SPSS Ver. 12.0 Results: Regarding the realationship between body composition and working pattern, shift worker group had a significantly higher level of body weight, ratio of body fat, visceral fat and abdominal fat than normal worker. Conclusion: From this study, we can know that shift work can influence on working women's body composition and obesity.

• Journal of Physiology & Pathology in Korean Medicine
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• v.27 no.2
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• pp.233-238
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• 2013

The development of healthy beverages are increasing by big concerns for well-being. The aim of this study is to develop cultivated wild ginseng-Kyungohkgo (CKOG) beverage using cultivated wild ginseng instead of natural wild ginseng for Kyungohkgo. To examine physiochemical properties of CKOG beverage, pH, degree Brix, acidity, Huntor color, particle size and sedimentation volume were measured. When compared with commercial KOG beverage, CKOG beverage was lower in pH, acidity, particle size and higher in sedimentation volume. In the sensory evaluation of CKOG beverage, the best recipe of healthy CKOG beverage was 20% CKOG, 5.7% honey, 0.2% citric acid and 74.1% of water. In stability testing, pH, degree Brix, acidity, Huntor color of CKOG beverage was not changed, microbes in CKOG beverage was not detected for 60 days. These results suggest that CKOG may have a possibility of development as healthy beverage.

• The Korea Journal of Herbology
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• v.26 no.1
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• pp.119-124
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• 2011

Objective : This study was carried out to investigate effect of korean medicinal herbs-included hair tonic (MHT) and food (MF) on hair growth in an alopecia model of C57BL/6 mice. Methods : Six-weeks old mice were given laboratory rodent chow diet for 1 week. Then, we used a depilatory for hair removal on mice. The next day, mice were randomized and separated in 3 groups of 6 mice; normal group (N, vehicle epidermal application+normal diet-treated group), positive control group (C, 3% minoxidil sulfate epidermal application+normal diet-treated group), and the treatment group (T, HT epidermal application+ MF diet-treated group). The hair regrowth was determined by photograph, which was taken at 7, 14 and 21 days. And scoring indices, hair density and hair thickness, were evaluated by Folliscope at same day. In addition, the hair regrowth was analyzed insulin-like growth factor (IGF-1) in the dorsal skin of mice. Results : As a result, not only external appearance but also hair density and hair thickness on dorsal skin were increased more in C, T groups than in N group at 21 days with mixed treatment. Therefore, distinct regrowth pattern is appeared by treatment of herbal tonic and natural food for 21 days. Also, the expressions of IGF-1 on dorsal skin were higher in C, T groups than in N group. Conclusion : These results suggested that this herbal hair tonic and natural food has hair growth promoting activities and may be useful for treatment of bald or alopecia.

• Journal of Physiology & Pathology in Korean Medicine
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• v.25 no.6
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• pp.1061-1068
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• 2011

Moxibustion is a treatment method for cold and pain in Korean medicine. But the systematic study of moxibustion were very few. This study was aimed to survey and evaluate moxibustion study in Korean medicine. We search the moxibustion study in journals related Korean medicine and http://oasis.kiom.re.kr. The period of the study from first issue to August, 2010. The search word were moxibustion, moxa in keyword and moxibustion treatment in title. We totally search 334 articles. But 175 articles were excluded because this study were not exactly moxibustion study, so we included and analyzed 159 articles. The study of moxibustion were 159 articles. Literature review were 35 articles, systematic review 8, heat experiment 10, in vivo or vitro 28 and survey investigation 3. Clinical articles of moxibustion related to Korean medical journals were 76. Before and after study were 31 articles, case report 20, cohort study 7, cross-sectional study 2, nonrandomized study 6, quasi randomized study 1, randomized clinical trials 9. This results showed that moxibustion study were smaller than acupuncture or herb and concentrated to pain and cold syndrome. We need further larger and diverse study of moxibustion.

• Journal of Ginseng Research
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• v.37 no.1
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• pp.37-44
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• 2013

Korean red ginseng is known to regulate the immune system and help the body struggle infection and disease. Cadmium is widely distributed in the environment due to its use in industry. Exposure to cadmium is problematic causing organ dysfunction. This study was conducted to evaluate the protective effect of Korean red ginseng extract (RGE) against cadmium-induced hepatotoxicity in rats. In experiments, animals were orally administrated with RGE (25, 50 mg/kg) for 7 d and then intravenously injected with cadmium ($CdCl_2$, 4 mg/kg) to induce acute hepatotoxicity. Cadmium caused the elevated levels of alanine aminotransferase, aspartate aminotransferase, and lactate dehydrogenase in serum. In contrast, pretreatment with RGE significantly reduced those serum indexes related with liver damage. In histopathological analysis, RGE decreased the centrilobular necrosis around central veins and the peripheral hemorrhage around portal triads. Moreover, RGE restored the deficit in hepatic glutathione level resulting from cadmium treatment. RGE also inhibited the increase in the expression of Bad, a representative apoptosis marker protein, induced by cadmium treatment. Collectively, these results demonstrate that RGE can reduce the cadmium-induced hepatic toxicity, partly via anti-oxidative and anti-apoptotic process.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.13 no.2
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• pp.182-187
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• 2000

Current status and quality administration of botanical products in America which has one of the biggest market need to be analyzed for the internationalization of oriental medicine. In this study, current status of botanical products as dietary supplements was analyzed and quality adminstration by United States Pharmacopoeia and National Formulary(USP-NF) was compared with The Korea Pharmacopoeia and botanical drug standard collection(KP), Even though the number of botanical products in USP-NF is small, it is rapidly increasing and more detailed compared with KP. Especially, reference standard compound should be determined for each botanical drugs, and more detailed standard for other items should be established in KP considering international trends. Though the history of botanical drugs in America is short, its annual market is about 3.2 billion dollar, so American administration system should be examined carefully for the internationalization of oriental medicine and related industry.

• Journal of Physiology & Pathology in Korean Medicine
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• v.26 no.2
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• pp.259-263
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• 2012

This case series present four patients, who were suffered from chest discomfort due to various underlying disease improved by korean traditional herbal medicine Haewoolhwajoongtang. Four patients in this study with chest discomfort due to various underlying disease in terms of the Western Medicine. But these four patients all have chest discomfort worsened at night caused by 'Yure(鬱熱)'. We treated this four patient by korean herbal medicine Haewoolhwajoong-tang. After treatment, their chief complains that chest discomfort was almost reduced. These result suggests that Haewoolhwajoong-tang was effective on chest discomfort caused by 'Yure(鬱熱)'.

• The Journal of Korean Medicine
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• v.32 no.6
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• pp.1-9
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• 2011

Objectives: We performed this study to compare the antidiabetic effects of Coptidis Rhizoma (CR) and its major component berberine with gliclazide. Materials and Methods: Diabetic rats induced by injection of streptozotocin (STZ) 55mg/kg were treated with CR 100, 200, 400mg/kg and berberine 100mg/kg. After rats were treated for 5 days, serum glucose, total cholesterol, triglyceride, BUN, creatinine and antioxidant levels were determined. Results: The cytotoxic effects of CR (0.1, 0.01, and 0.001mg/mL), berberine and gliclazide ($0.1{\mu}M$, $1{\mu}M$, and $10{\mu}M$) were tested in rat insulinoma (RIN) cells induced with 5mM STZ. The levels of fasting blood glucose, total cholesterol, triglyceride, BUN and creatinine of CR and berberine treated groups were reduced as much as that of gliclazide group in comparison to control groups, whereas total antioxidant levels increased. In vitro experiments showed that CR and berberine have a cytoprotective effect on RIN cells.

• 중국학논총
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• no.64
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• pp.157-182
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• 2019

中国加入WTO后, 在经济快速发展, 产业结构逐渐高度化的情况下, 以2015年获得中医科学院所属传统医学家屠呦呦教授诺贝尔生理医学奖为契机, 在传统医学"中医药崛起"领域也走向世界. 尽管近年来西方医学取得了辉煌发展, 但近年来化学药品的副作用, 老龄化时期医疗费用支出扩大等新问题, 使天然物料生物新药开发蓬勃发展, 传统医药市场规模不断扩大. 属于传统医药的中医药产业一直受到中国领导人的关注, 中医药在防治非典传染病中的作用, 中医科学院的屠呦呦教授获得诺贝尔生理医学奖等, 中医药政策得到积极促进. 与此形成鲜明对比的是, 我国韓医药产业在"西·韓医药"纠纷仍在持续的情况下, 尽管政府作出了努力, 但并未取得显著成效. 因此, 本文首先對中医药产业的概念, 范畴和地位詳細硏究, 并详细了解中医药产业政策在时间上是如何推进的. 然后详细分析中医药医疗服务和制造业, 国际化领域取得了哪些成就. 最後让我们来看看对我们韓医药产业发展的启示是什么.

• Journal of Physiology & Pathology in Korean Medicine
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• v.23 no.5
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• pp.1178-1182
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• 2009

This study was designed to analyze the results of Vaso-Aging Degree in Oriental medical examination. The subjects were workers in the automobile manufacturing industry. The subjects consisted of 24,077 industrial workers who had received Oriental medical examination by Oriental medicine and they submitted questionnaires about drinking history and smoking history, during 9 months from March to November. They were categorized by job class, drinking history and smoking history, exercising history. The percentage of Vaso-Aging Degree were measured by using SA3000P(Medicore, Seoul, Korea). We analyzed the relationship between job class, drinking history, smoking history, exercising history and Vaso-Aging Degree using ${\chi}2$-test of the SPSS Ver. 14.0. In job class, Sales personnel were apt to have a higher level of Vaso-Aging Degree than Office workers. And getting older workers are, the higher Vaso-Aging Degree becomes. Vaso-Aging Degree of the Drinker group showed a higher level than the Non-Drinker group. Vaso-Aging Degree of Smoker group were higher than the Non-smoker group. On the other hand, Vafo-Aging Degree of Non-Exerciser group were higher than the Exerciser group. They have to manage Vaso-Aging Degree closely and educate the workers to quit smoking and drinking for their health promotion. Furthermore, continuous health check up needs to be done connectedly.