• 대한한의학회지
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• 제25권1호
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• pp.129-141
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• 2004

Objective: The purpose of this clinical observation was to estimate the efficacy of Quetong & Voice on the abatement of subjective symptoms related nose & pharynx. Methods: We observed 46 patients who visited Kang-Nam oriental hospital with subjective symptoms related nose & pharynx that were prescribed Quetong or Voice. We made an inquiry into the inconvenience, side effect, abatement of subjective symptoms, etc. We used the Wilcoxon signed rank test. Results and Conclusions: 1. The distribution of age & sex was as fallows: 21-30 years(34.8%) were the most, 31-40 years(26.1 %) were the second, 1-10 years(24.0%) were the third. Total patient numbers for men and women were 15 men(32.6%), 31 women(67.4%). 2. The distribution of prescribed aerosols for 46 patients: 5 cases(10.9%) prescribed Quetong, 22 cases(47.9%) prescribed Voice, and 19 cases(41.3%) prescribed Quetong & Voice. 3. The duration of use: 12 cases(26.1 %) used 1 week, 19 cases(41.3%) used 1-2 weeks, 9 cases(19.6%) used 2-4 weeks, 4 cases(8.7%) used 4-8 weeks, and 2 cases(4.3%) used above 8 weeks. 4. The frequency of use: The most patients used 1-5 times(69.6%) or 5-10 times(21.7%) for a day. 5. Quetong & Voice were effective on abatement of subjective symptoms(rhinorrhea, nasal obstruction, pharyngalgia, sneeze or cough, post nasal drip, pharyngeal pruritus, pharyngeal dryness, nasal dryness, and globus hystericus). 6. We must prescribe Quetong to the child or the sensitive patients with discretion becouse of the sting. 7. The side effect was not occurred in all of 46 patients.

• 대한통합의학회지
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• 제5권3호
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• pp.29-37
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• 2017

Purpose: The purpose of this study was to classify patients with chronic back pain according to the degree of their back pain, and to compare the pain dysfunction index with the qualitative changes in abdominal muscles. Therefore, we aimed to provide a basis for the treatment intervention method for patients with back pain. Methods: Twenty patients with chronic back pain were purposive sample to a group of 10 patients with a back pain index of 60 % or more and a group with less than 60 % of back pain, and the subjects who voluntarily participated in the study After receiving the letter, I conducted the research the dysfunction of back pain was measured by the Korean version of the Oswestry Disability Index (KODI), and the ultrasonic wave (Ultrasound MyLabOne, ESAOTE, Italy) And the white area index, and the abdominal muscle movement was used as the exercise instrument POWER breathe K5 (Hab direct, UK), which strengthens the respiratory muscles through threshold-muscle traction. Result: In this study, patients with chronic back pain were subjected to breathing exercises, which led to the decrease in back pain dysfunction. The ultrasonographic analysis of abdominal muscles revealed that both the white area index and muscle image density in the skeletal muscle and in the outer muscle of the abdomen gradually decreased over time. Conclusion: It is thought that introducing back pain patients to abdominal muscle reinforcement training is effective in improving the functions of the patients' muscles, thus increasing their quality of life.

• 대한한방부인과학회지
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• 제28권4호
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• pp.11-20
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• 2015

Objectives The purpose of this study was to examine the relationship between cold hypersensitivity and bone mineral density. Methods 28 outpatients who visited OO University Oriental Hospital from July 11th, 2013 to August 28th, 2013 were analyzed. Patients were subjected to thermometer, and those with thermal difference greater than 0.3 ℃ between upper arm and palm and also with more than VAS 4 of cold hypersensitivity were diagnosed with cold sensitivity. Lumba spine (L2-4) and heel bone measurement were obtained on dual energy X-ray absorptiometry (DEXA) and Quantitative Computed Tomography (QCT). Results 1. There was statistically significant correlation between T-score of DEXA and body weight (0.522), BMI (0.643), OSTA (Osteoporosis elf-assesment Tool for Asians, 0.579), BMI, T-score and Z-score of QCT. OSTA and T-score of QCT (0.521) also had statistically significance. 2. There was no statistically significant correlation between body fat, abdominal obesity rate, degree of cold hypersensitivity, upper arm and palm's temperature difference, palm temperature, height and Z-score, T-score of QCT or T-sore of DEXA. Conclusions Bone mineral density was lower in women who had cold hypersensitivity of hand and feet. But there was no statistically significant correlation between bone mineral density and degree of cold hypersensitivity, upper arm and palm’s temperature difference.

• Journal of Ginseng Research
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• 제40권3호
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• pp.211-219
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• 2016

Background: Panax ginseng root is used in traditional oriental medicine for human health. Its main active components such as saponins and polysaccharides have been widely evaluated for treating diseases, but secondary active components such as oligosaccharides have been rarely studied. This study aimed to assess the impact of water-soluble ginseng oligosaccharides (WGOS), which were isolated from the warm-water extract of Panax ginseng root, on scopolamine-induced cognitive impairment in mice and its antineuroinflammatory mechanisms. Methods: We investigated the impact of WGOS on scopolamine-induced cognitive impairment in mice by using Morris water maze and novel object recognition task. We also analyzed the impact of WGOS on scopolamine-induced inflammatory response (e.g., the hyperexpression of proinflammatory cytokines IL-$1{\beta}$ and IL-6 and astrocyte activation) by quantitative real-time polymerase chain reaction and glial fibrillary acid protein (GFAP) immunohistochemical staining. Results: WGOS pretreatment protected against scopolamine-induced learning and memory deficits in the Morris water maze and in the novel object recognition task. Furthermore, WGOS pretreatment downregulated scopolamine-induced hyperexpression of proinflammatory cytokines interleukin (IL)-$1{\beta}$ and IL-6 mRNA and astrocyte activation in the hippocampus. These results indicate that WGOS can protect against scopolamine-induced alterations in learning and memory and inflammatory response. Conclusion: Our data suggest that WGOS may be beneficial as a medicine or functional food supplement to treat disorders with cognitive deficits and increased inflammation.

• Journal of Acupuncture Research
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• 제23권5호
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• pp.93-103
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• 2006

Objectives : To Investigate Severity Measurement and the Correlation between Acupoints on the Face and the Upper limb in Bell's Palsy Patients by Using of DITI. Methods : By using of DITI, thermal differences between abnormal and normal site in acupoints on the face and the upper limbs of 21 Bell's palsy patients who visited department of Acupuncture & Moxibustion in National Medical Center from 1st February 2004 to 31th December 2005 were measured around 7days after the onset in standardized Environment. The patients were classified by severity scale. Results : The means of thermal difference of the facial acupoints were significantly distributed at each grade. The thermal difference of GB14 was significantly correlated with thermal difference of TE4, the thermal difference of S4 was significantly correlated with thermal difference of L6 and SI4, the thermal difference of STI18 was significantly correlated with thermal difference of LI11 and the thermal difference of LI20 was significantly correlated with thermal difference of LI11 and LI4. The thermal differences of acupoints in Large intestine meridian were more closely correlated with thermal difference of the facial acupoints than thermal difference of acupoints in the other meridians. Conclusion : Severity of Bell's palsy can be presumed through DITI image. And the theory of meridian was confirmed by DITI in Bell's palsy patients.

• Advances in Traditional Medicine
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• 제9권2호
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• pp.174-181
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• 2009

Pterocarpus marsupium, Clitoria ternatea, and Sanseveiria cylindrica are some of the important and endangered medicinal plant species of India. Despite of medicinal properties, antibacterial potential of the plants have not yet been explored. The present study was designed to optimize the in vitro technique for micropropagation and to screen the extracts from leaves and in vitro raised calli for antibacterial properties. Excised leaf-explants from the parent plants were surface sterilized and cultivated on Murashige & Skoog's (MS) medium containing $N^6$-benzyladenine (BA) in concentrations of 1, 2, 5, and $10{\mu}M$. Optimal growth of calli was noticed at a concentration of $5{\mu}M$, therefore the extracts from calli grown at this concentration were further studied for antibacterial activity. Both alcoholic and aqueous extracts from leaves of respective plants, and their in vitro raised calli were tested for antibacterial activity by agar well diffusion method against a range of Gram-positive and Gram-negative bacteria. Aqueous extracts showed antibacterial activity against limited number of bacterial species; notably the extracts of C. ternatea which showed antibacterial activity against Streptococcus pyogenes, Bacillus subtilis and Bacillus cereus. Alcoholic extracts of all three plants showed antibacterial activity against a wider range of bacteria. Among the Gram-positive bacteria, extracts from C. ternatea showed strong antibacterial activity against Bacillus spp., whereas the extracts of S. cylindrica showed good antibacterial potential for Staphylococcus aureus, S. epidermidis and S. pyogenes. The extracts from all three plants showed antibacterial activity against Gram-negative bacteria, including, Salmonella spp. and Shigella dysenteriae; organisms causing enteric fever and dysentery. In most of the cases, the extracts from respective calli showed comparable, and in some cases better, result in comparison to the extracts from parent leaves. To the best of our knowledge this is the first preliminary report on antibacterial potential, especially through calli extracts, of these plants; and in vitro cultivation of the explants may be used to obtain phytotherapeutic compounds.

• 한방안이비인후피부과학회지
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• 제17권2호
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• pp.87-93
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• 2004

Objective: We would like to find out the correlation between acne distribution in the jaw and the emmeniopathy. Methods: The clinical studies were made on 43 cases of acne vulgaris who visited to Department of Dermatology, Dongguk University Gangnam Oriental Medical Hospital during from August, 2002 to July, 2004. We divided the patients into two groups. A group had the emmeniopathy. B group didn't have the emmeniopathy. In the acne grade and the number of acne, we investigated the difference between A and B group statistically. We used the statical methods of student's t-test on the number of acne and wilcoxon rank sum test on acne grade. Results: The mean age was 25.8${\pm}$4.80 in A group and 27.6${\pm}$5.68 in B group. There were painful menstruation, quality of thickness, menstrual cycle disorder, menstrual amount disorder, dark purple color, premenstrual acne in A group with the emmeniopathy. The acne grade was 1.69${\pm}$1.28 in A group, 1.43${\pm}$1.28 in B group. The number of acne was 3.66${\pm}$3.15 in A group, 4.36${\pm}$4.07 in B group. P-value was 0.52 in acne grade and 0.25 in the number of acne. We investigated no difference between A and B group statistically on acne grade and the number of acne. Conclusions: We needed the further study about the factor which affect on acne distribution and emmeniopathy.

• 대한본초학회지
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• 제32권6호
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• pp.31-39
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• 2017

Objectives : Menopausal symptoms are characteristic symptoms which are occur in women before and after menopause. In Western medicine, hormone therapies are mainly used but patients show reluctance because they exhibit serious side effects. In Oriental medicine, there are also limits to the treatment. So I tried to find a new easily accessible treatment. I performed the experiments to verify the effect of natural dyed apparel with Indigo and Schisandra fruit. Methods : This experiment was performed on 30 women who were experiencing menopausal symptoms. We checked the participant's general condition through questionnaire and physical condition with inbody test and made natural-dyed living suit style dresses. We asked the women to wear the apparel for four weeks. They checked for changes in symptoms weekly with kupperman's index. Results : The main symptoms of participants are sweating, hot flushes, joint pain. After wearing of the apparel, there were decreased hot flushes, sleep improvement, psychological stability etc. According to the kupperman's index, patients with mild symptoms were 13.3% at first week to start the experiment but four weeks later, patients with mild symptoms were increased to 50%. On the other hand, patients with severe symptoms were decreased 33.3% to 6.7%. In the test results, there was a significant decrease in 1, 2 and 3 weeks, there was a decrease in 4 weeks but no significance in the figure Conclusion : Natural dyed apprel with Indigo and Schisandra fruit was effective on treating women who were experiencing menopausal symptoms.

• Journal of Nutrition and Health
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• 제45권2호
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• pp.192-200
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• 2012

Fruits are generally recommended for a balanced meal, as they are good sources of vitamins, minerals, and fiber, which may improve blood glucose control. However, fruits have simple sugars with a wide glycemic index (GI) range. The purpose of this study was to analyze the sugar content and composition and to determine the glycemic indices of the most frequently consumed fruits in Korea, including apple, tangerine, pear, water melon, persimmon, grape, oriental melon, and peach. The sugar content and composition of the fruits were analyzed by high performance anion-exchange chromatography (Dinonex model DX-600). The GI of the fruits was measured in 13 healthy subjects (seven females and six males) after permission was received from the University Hospital institutional review board (KHU-IRB 1114-06). The subjects consumed 50 g of glucose as a reference and carbohydrate portions of eight fruits. Blood samples were collected at 0, 30, 60, 90, and 120 min after consuming the fruits. The GI values for the fruits were calculated by expressing the increase in the area under the blood glucose response curve for each subject. As a result, the total sugar contents of 100 g fruits were: grape (13.9 g), apple (12.3 g), persimmon (11.9 g), oriental melon (11.2 g), watermelon (9.3 g), tangerine (8.9 g), peach (8.6 g), and pear (8.3 g). The GI values of the fruits were as follows: GI value of peach ($56.5{\pm}14.17$), watermelon ($53.5{\pm}18.07$), oriental melon ($51.2{\pm}18.14$), tangerine ($50.4{\pm}15.16$), grape ($48.1{\pm}14.05$), persimmon ($42.9{\pm}18.92$), pear ($35.7{\pm}14.38$), and apple ($33.5{\pm}11.92$). These findings will help individuals choose fruit for controlling blood sugar.

• Journal of Acupuncture Research
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• 제23권1호
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• pp.53-62
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• 2006

Objectives : Because of the recent well-being syndrome, concerns about smoking cessation, as well as dietary improvement and exercise, are being increased. There are various methods for smoking cessation. Among them, recently acupuncture treatment is verified through diverse attempts. This research was conducted to examine the effects of acupuncture treatment especially on juvenile smoking cessation. Methods : From April 04 to Oct 04, this study had investigated 93 middle and high school students. 5 times of acupuncture treatment were given to each participant, and the survey was executed before and after each treatment. The acupuncture was treated to the ear alternately twice a week. The evaluation was taken before the treatment after the 1st treatment, and the 5th treatment with 6 questions of amount of daily smoking, desire to smoke, taste of smoking, subjective symptoms, smoking cessation proportion, Fagerstorm Tolerance Questionaire point. Results : Regarding amount of daily smoking, the significant tendency between before and after the treatment varied, but between the 1st and the 5th treatment, there was no difference. The 1st treatment had caused desire to smoke reduction in 46 students(49.5%), but the 5th treatment didn't have much effects on desire to smoke(43 persons; 46.2%). After treatment, 37.6% had no effect in taste of smoking, while the rest of them showed various reactions. Also, there were no difference of significant tendency between the 1st and 5th treatments. In respect to the amount of smoking, 70% of them achieved smoking cessation, or reduction in smoking, but about 25% of them showed no changes. Various subjective symptoms such as lethargy, decrease of appetite, headache were shown, and especially desire to smoke was shown pervasively. Regarding Fagerstorm Tolerance Questionaire point, the average of significant tendency in point after the treatment had decreased(3.1+-2.4 to 2.1+-2.1, p<0.0001). but for those students who had tried smoking cessation less than 5 times, Fagerstorm Tolerance Questionaire point had decreased significantly, but for the others who had tried smoking cessation more than 5times, there were no difference. Conclusion : In regard to 6 questions of amount of daily smoking, desire to smoke, taste of smoking, subjective symptoms, smoking cessation proportion, Fagerstorm Tolerance Questionaire point, various conclusion is drawn. These results suggest that acupuncture treatment on juvenile may have the tendency of smoking cessation.