• 대한한방내과학회지
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• 제30권1호
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• pp.249-255
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• 2009

Currently, drug-induced liver injury (DILl) has been reported to be common cause of acute hepatitis, and oriental medicine and folk remedies are no exception. However, because many studies about DILl have been reported by western medical society. they has taken the initiative of DILl not only for western drugs but also herbs. So, academia of oriental medicine should make an effort to progress herb-related DILl studies. We describe a patient of acute liver injury which had been caused by comfrey, albizzia julibrissin, ulmus davidiana var. japonica, red ginseng. We hope that this report helps for studying the diagnosis and management of herb-derived DILl. and for establishing a standard of oriental therapy to DILL.

• 혜화의학회지
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• 제23권1호
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• pp.167-172
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• 2014

Purpose : The purpose of this report is to record the effects of oriental treatments for the abnormal uterine bleeding Methods : This is a case report of a 16 year old female patient suffering from abnormal uterine bleeding for eight months. She was treated by Herb therapy for 3 months. During the treatments, we checked changes of symptoms. Results : After Herb therapy, abnormal uterine bleeding was disappeared and recovered the normal menstrual cycle. Conclusion : This clinical case shows that Herb therapy has potentially effective for abnormal uterine bleeding. More clinical data and studies are required for the treatment of abnormal uterine bleeding.

• 대한한의학회지
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• 제29권1호
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• pp.207-222
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• 2008

Objectives : I report 12 cases of strabismus presented at [Oriental Medical Clinic of Kim Joong-Ho and Strabismus - Amblyopia Clinic, East-West Neo Medical Center, Kyung Hee University] from 2nd March 2006 to 29th February 2008. All have experienced good improvement of strabismus by treatment with Oriental medicine. Methods : Patients were treated with acupuncture, infra-red and herb medicine. The acupuncture points of (B2) 絲竹空(TE23) 承泣(S1) 陽白(G14) 太陽(E36) were mainly used. Herb medicines prescribed were Gagamseunggal-tang and Gamiboik-tang. Results : 9 cases of strabismus were caused by paralysis of the sixth cranial nerve and the third cranial nerve, while 3 cases happened with concomitant strabismus of esotropia and exotropia. They were treated to recover paralytic muscles and unelastic muscles around the eyes and face. Treatment took between 1 and 8 months. Conclusions : In the results of this study, treatment was effective to correct position at the eyeball. I report it is possible to treat strabismus successfully with Oriental medicine in a shorter time compared to western medicine.

• 대한한방부인과학회지
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• 제18권4호
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• pp.153-164
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• 2005

Purpose : This study was designed to make a basis of in vivo or clinical study about colporrhea. Methods : This study is based on Yang's study, An investigation on the prescriptions of colporrhea(1999). We investigate the prescriptions in the Yang's study and examine the frequency of metioned single herb. Also we investigate the herb's classification. Results and Conclusion : 1) Single herb frequently used in the prescriptions was as follows. (()- Frequency) Paeoniae Radix Alba白芍藥(16), Glycyrrhizae Radix甘草(15), Poria白茯?(13),　Angelicae gigantis Radix當歸, Citri Pericapium陳皮(11), Atractylodis macrocephalae Rhizoma白朮(10), Zingiberis Rhizoma乾薑　, Atractylodis Rhizoma蒼朮, Ailanthi Cortex樗根白皮, Phellodendri Cortex黃柏, Ginseng Radix人蔘, Cyperi Rhizoma香附子(9),　Dioscoreae Rhizoma山藥, Corni Fructus山茱萸, Bupleuri Radix柴胡, Cnidii Rhizoma川芎, Gardeniae Fructus梔子(8), Rehmanniae Radix preparat熟地黃, Pinelliae Rhizoma半夏(7), Foeniculi Fructus小茴香, Scutellariae Radix黃芩, Angelicae dahuricae Radix白芷, Cinnamomi肉桂(5), CortexAlismatis Rhizoma澤瀉, Moutan Cortex牧丹皮, Aconiti iateralis preparata Radix附子, Plantaginis Semen車前子(4), Ostreae Concha牡蠣, Euphorbiae pekinensis Radix大戟, Aucklandiae Radix木香, Rhei Radix et Rhizoma大黃, Ledebouriellae Radix防風, Astragali Radix黃?, Rehmanniae Radix生地黃, Daphnis genkwa Flos莞花, Evodiae Fructus吳茱萸, Euphorbiae kansui Radix甘遂(3) 2) Herbs specifically frequently used in the prescriptions of colporrhea were as follows. Atractylodis Rhizoma蒼朮, Ailanthi Cortex樗根白皮, Phellodendri Cortex黃柏, Cyperi Rhizoma香附子, Bupleuri Radix柴胡, Gardeniae Fructus梔子　3)Herbs frequently used were classified by herbal medicine's classification. The　result was as follows. (()-The number of herbs)　補益藥（1９). 淸熱藥(18). 解表藥(10), 收澁藥(9), 溫裏藥(7), 理氣藥(6), 利水?濕藥(6), 瀉下藥（５)

• 대한약침학회지
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• 제3권2호
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• pp.79-97
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• 2000

Objectives : To investigate the effects of herb-acupunctures of Qi tonification herbs or formula on the rat immune depression induced by an anticancer drug, methotrexate (MTX) Methods: Animals were divided into 5 groups; Normal control group was not given any treatment. Immune depression was induced by oral administration of 1mg/kg MTX b.i.d for 4 days in Control, Sample I, II, and III groups. We treated on CV 4 (Guanyuan) with saline, Bojoongiggi-tang (Buzhongyiqi-tang), Ginseng Radix and Astragali Radix herb-acupunctures in Control, Sample I, II, and Ill groups, respectively. In both blood and spleen, the assessment of CD4+ T-cell count, CD8+ T-cell count, CD4/CD8 T-cell ratio was performed. Results: Here we show that 3 herb- acupuncture groups have an influence, to some extent, on CD4+ and CD8+ T-cell counts and CD4/CD8 T-cell ratio in both blood and spleen. Astragali Radix herb-acupuncture, in particular, was found to have significantly increased CD4+ T-cell count in blood and CD4/CD8 T-cell ratio in blood and spleen. Conclusions: The results of this study suggest that herb-acupunctures of Bojoongiggi-tang (Buzhongyiqi-tang), Ginseng Radix and Astragali Radix may have an influence over rat immune depression induced by MTX.

• 생약학회지
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• 제3권2호
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• pp.57-64
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• 1972

For the purpose of scientific evaluation of oriental medicine, statistical analyses of oriental medicine formularies have been attempted. Four hundred and sixty seven prescriptions in 'Bang-Yak-Hap-Pyon', the most popular formulary of oriental medicine in Korea, were analysed to obtain statistical characteristics on the prescription frequency and origin distribution of two hundred and ninety three herb drugs.

• 대한한방내과학회지
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• 제25권4호
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• pp.1-8
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• 2004

Objectives: The prostatitis is characterized as relatively uncurable chronic recurrent illness. Because it is so difficult to treat, this study was designed to evaluate the clinical effects of herb medicine, acupuncture, and herbal acupuncture therapy on chronic prostatitis. Methods: A clinical observation was made on thirty patients with chronic prostatitis. They were treated with herb medicine, acupuncture, and herbal acupuncture therapy. Before and after treatment we measured NIH-CPSI(National Institutes of Health Chronic Prostatitis Symptom Index). Results: After treatment NIH-CPSI was decreased considerably. Conclusions: This suggests a role for oriental medical therapy in treating prostatic diseases. Further study into approach and application of these treatments for prostatitis is needed.

• 대한한방부인과학회지
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• 제21권3호
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• pp.167-178
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• 2008

Purpose: Many breastfeeding women have used complementary and alternative medicine, but the guideline for lactation does not exist on complementary medicine. This study is to investigate efficacy and safety of complementary and alternative medicine in breastfeeding. Methods: We searched for papers which had breastfeeding, complementary medicine, acupuncture and herb in the pubmed, scopus site and Korean journals. Results: 38 papers were found. Acupuncture could have the efficacy on hypogalatia and mastitis. Compound herb therapy had effect on hypogalactia, but none of herbs were investigated for safety all except for St John's wort. So more clinical trials about herbs would be needed. Massage and the other complementary therapies would be helpful for breastfeeding mother. Conclusion: Acupuncture could be a good treatment for hypogalactia and inflammation of the breast. For making guidelines on complementary and alternative medicine during lactation, more research will be needed.

• 대한중풍순환신경학회지
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• 제10권1호
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• pp.54-61
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• 2009

Arteriosclerosis is a pathologic term that contains hardening of arterial wall, loss of arterial elasticity and stenosis of artery. To diagnose this disease, conventional angiography, MRA, transcranial doppler ultrasonography are commonly used. And it causes various clinical phases by a region of the disease. In oriental medicine, arteriosclerosis is classified into congested fluids(痰飮), blood stasis(瘀血), stagnation of Gi(氣滯) and treated by Herb-Med, acupuncture, cupping, moxibustion, and the like. The purpose of this study was to investigate the effect of oriental medical therapy on cerebral arteriosclerosis. A patient with cerebrovascular disease admitted due to dizziness, mild dysarthria, tinnitus, anxiety disorder and his Brain MRA showed severe arteriosclerosis in right anterior cerebral artery(ACA) and middle cerebral artery(MCA). Every day, we administered to patient Herb Med and Herb pills. Also, acupuncture, moxibustion were done, too. As a result of the treatment, the patient's follow up Brain MRA showed improved state of ACA stenosis.

• 농업생명과학연구
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• 제50권5호
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• pp.81-93
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• 2016

지황은 현삼과(Scrophulariaceae)에 속하는 다년생 초본식물 Rehmannia glutinosa(Gaertn.) DC.로서 한의학에서는 뿌리를 지황(地黃)이라는 한약재로 이용하고 있다. 지황은 선지황(鮮地黃), 생지황(生地黃), 숙지황(熟地黃) 등으로 널리 사용되고 있지만 종자파종에 의한 재배보다 종근을 이용한 영양번식으로 재배하고 있다. 종근을 이용한 재배법은 뿌리 썩음병으로 인해 종근의 관리와 생산성이 높은 고품질의 지황 생산이 어려운 실정이다. 본 연구에서는 형태적 특징과 유전자 분석을 통해 기원이 검증된 지황 기원식물을 이용하여 정확한 기원의 무균 배양묘와 종근 생산을 위한 최적 조건을 확립하고자 하였다. 기내배양묘 생산에 필요한 최적의 생장율과 다개체 형성율, 그리고 뿌리 형성율 및 비대조건을 탐색한 결과, WPM 배지와 1.0mg/L의 IAA와 0.5mg/L의 IBA 옥신계 생장조절제가 첨가된 배지(WPM + IAA 1.0mg/L + IBA 0.5mg/L)에서 최적 생장율과 뿌리다개체 형성율을 나타내었으며, 0.1mg/L의 NAA가 첨가된 WPM 배지(WPM + NAA 0.1mg/L)에서 가장 많은 수의 뿌리가 형성되었고 비대율도 높게 나타났다. 이러한 최적조건에서 생산한 기내식물체는 토양 순화 후 정식하였을 경우에도 높은 뿌리형성율과 지속적인 비대 효과를 보였다. 이상의 결과는 지황의 무균 배양묘 생산과 배양묘기반 종근 생산을 통해 지황 대량 생산에 필요한 배양묘와 종근 생산에 유용하게 활용될 수 있을 것으로 판단되며, 고품질 지황 생산량에기여할 것으로 사료된다.