• 통상정보연구
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• 제14권4호
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• pp.153-174
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• 2012

본 연구의 목적은 우리나라의 수출입 제조 기업을 대상으로 글로벌 아웃소싱의 성과에 영향을 미치는 요인을 분석한 것으로 본 연구에서는 조직 역량, 유연성, 정보 공유, 파트너십을 설정하고 기업의 성과와 인과 관계를 확인하고자 하였다. 이를 통해 글로벌 아웃소싱 성과에 영향을 미치는 정도를 파악하여 글로벌 소싱 활성화 방안을 모색하며 향후 글로벌 소싱 확산에 기여하고자 함에 있다. 이를 위해 본 논문에서는 글로벌 소싱의 개념적 정의와 특징을 분석하였고 글로벌 소싱 국내외 현황을 고찰하였다. 선행연구는 주로 거래비용 이론, 자원기반 이론에 바탕을 둔 기존의 이론 및 실증연구를 토대로 연구모형과 가설을 도출하였고, 연구모형에 적합한 측정문항을 개발하였다. 그리고 이러한 측정문항을 바탕으로 국내 수출입기업을 대상으로 설문조사를 실시하고 실증 분석하였다. 설정된 가설검증에 앞서 글로벌 소싱 구현수준에 대한 기초자료 분석과 각 측정변수들에 대한 신뢰성 분석과 타당성 분석을 SPSS 18.0 통계 패키지 프로그램을 이용하여 수행하였다. 또한 글로벌 소싱 성과관련 4개의 연구가설은 회귀분석 모형을 이용한 것으로 검증하였다.

• Molecules and Cells
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• 제44권9호
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• pp.627-636
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• 2021

The three-dimensional organization of chromatin and its time-dependent changes greatly affect virtually every cellular function, especially DNA replication, genome maintenance, transcription regulation, and cell differentiation. Sequencing-based techniques such as ChIP-seq, ATAC-seq, and Hi-C provide abundant information on how genomic elements are coupled with regulatory proteins and functionally organized into hierarchical domains through their interactions. However, visualizing the time-dependent changes of such organization in individual cells remains challenging. Recent developments of CRISPR systems for site-specific fluorescent labeling of genomic loci have provided promising strategies for visualizing chromatin dynamics in live cells. However, there are several limiting factors, including background signals, off-target binding of CRISPR, and rapid photobleaching of the fluorophores, requiring a large number of target-bound CRISPR complexes to reliably distinguish the target-specific foci from the background. Various modifications have been engineered into the CRISPR system to enhance the signal-to-background ratio and signal longevity to detect target foci more reliably and efficiently, and to reduce the required target size. In this review, we comprehensively compare the performances of recently developed CRISPR designs for improved visualization of genomic loci in terms of the reliability of target detection, the ability to detect small repeat loci, and the allowed time of live tracking. Longer observation of genomic loci allows the detailed identification of the dynamic characteristics of chromatin. The diffusion properties of chromatin found in recent studies are reviewed, which provide suggestions for the underlying biological processes.

• 한국병원경영학회지
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• 제27권4호
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• pp.36-55
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• 2022

Purpose: This study explores the diffusion factors of corporate entrepreneurship among members of medical institutions. Methodology/Approach: The study explores the case of Granum Sinapis Center at Seoul St. Mary's Hospital, the first medical institution to establish a support organization for "innovation and start-up" as well as examines the changes in individual perceptions of participants in the institution's in-house contest. Among the 140 participants in the 2nd Contest held in 2022, seven participants were selected for interview in consideration of their job occupation and years of service. In-depth interviews were conducted for each individual. Findings: The participants applied for the contest under the direct and indirect influence of co-workers as well as compensatory factors. An individual's corporate entrepreneurial characteristics can be innate or acquired. The participants of the in-house contest had a positive experience in contrast to the existing organizational culture. The results reveal that emotional support from top and middle managers, along with the role of dedicated departments, can affect innovative behavior. Practical Implications: Contest participants reported personal growth, improved job satisfaction, and a change in perception of the organizational culture; they expressed their willingness to recommend. The results confirm the need to support such systems and shift focus to managerial (emotional) support and dedicated resources for developing individual entrepreneurship.

• 대한영상의학회지
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• 제84권3호
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• pp.698-704
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• 2023

중신 유사 선종은 2020년 World Health Organization 분류체계에서 자궁내막암의 한 아형으로 새롭게 분류되었고, 드물기 때문에 잘 알려지지 않은 질환이다. 저자들이 아는 한, 영어 문헌에서 영상의학적 소견은 아직 보고된 바 없다. 자궁의 중신 유사 선종은 일반적인 자궁내막암에 비해 예후가 좋지 않고 더 공격적인 생물학적 양상을 보인다. 저자들은 65세 여성의 자궁 체부에 생긴 중신 유사 선종의 영상의학적 소견에 대하여 보고하고자 한다. 자궁내막 고형 종괴가 심부 자궁근 침범을 보였고, 조영 증강은 잘되지 않았고 중등도의 확산제한을 보였다.

• Brain Tumor Research and Treatment
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• 제6권2호
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• pp.60-67
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• 2018

Background Recently, modern technology such as diffusion tensor imaging (DTI), neuro-navigation and intraoperative neurophysiological monitoring (IOM) have been actively adopted for the treatment of thalamic tumors. We evaluated surgical outcomes and efficacy of the aforementioned technologies for the treatment of pediatric thalamic tumors. Methods We retrospectively reviewed clinical data from 37 children with thalamic tumors between 2004 and 2017. There were 44 operations (27 tumor resections, 17 biopsies). DTI was employed in 17 cases, neuro-navigation in 23 cases and IOM in 14 cases. All diagnoses were revised according to the 2016 World Health Organization Classification of Tumors of the Central Nervous System. Progression-free survival (PFS) and overall survival (OS) rates were calculated, and relevant prognostic factors were analyzed. The median follow-up duration was 19 months. Results Fifteen cases were gross total resections (GTR), 6 subtotal resections (STR), and 6 partial resections (PR). Neurological status did not worsen after 22 tumor resections. There were statistically significant differences in terms of the extent of resection between the groups with DTI, neuro-navigation and IOM (n=12, GTR or STR=12) and the group without at least one of the three techniques (n= 15, GTR or STR=9, p=0.020). The mean PFS was $87.2{\pm}38.0$ months, and the mean OS $90.7{\pm}36.1$ months. The 5-year PFS was 37%, and the 5-year OS 47%. The histological grade ($p{\leq}0.001$) and adjuvant therapy (done vs. not done, p=0.016) were significantly related to longer PFS. The histological grade (p=0.002) and the extent of removal (GTR/STR vs. PR/biopsy, p=0.047) were significantly related to longer OS. Conclusion Maximal surgical resection was achieved with acceptable morbidity in children with thalamic tumors by employing DTI, neuro-navigation and IOM. Maximal tumor resection was a relevant clinical factor affecting OS; therefore, it should be considered the initial therapeutic option for pediatric thalamic tumors.

• 한국경영과학회:학술대회논문집
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• 한국경영과학회 2001년도 추계학술대회 논문집
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• pp.79-82
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• 2001

The wide use of Information Technology(IT), especially the rapid diffusion of the internet, brings us a new paradigm, called "Electronic Commerce", or "Digital Economy." The paradigm is regarded as a business strategy essential to organization's competitive advantage. Because very few studies have been performed in the area of e-strategy, especially in the combined strategy of clicks and mortars, a research on this area is needed. The main questions of this study are empirically to validate the usefulness and the applicability of a decision roadmap and to analyze the situation of Korean firms based on the decision roadmap. Major results of this study are as follows; First, there is an evidence that the roadmap can be applied to firms regardless of its industry and size. Second, usefulness of the roadmap is proved since companies that followed the prescription of the decision roadmap showed high degree of satisfaction with online sales amount. Third, Korean firms in general do not achieve the ideal degree of integration (or separation), especially in terms of management and operation. In conclusion, this study provides e-business strategy planners some guidelines about how to achieve right mix of on-line and off-line business.

• Asian Journal of Atmospheric Environment
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• 제5권3호
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• pp.172-180
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• 2011

The transfer of microorganisms is important process for ecosystems. Microorganisms in dryland can transport itself to wetland through atmospheric diffusion, but only few papers reported about the atmospheric bioaerosol present over dryland. We carried out the direct sampling using a tethered balloon over Dunhuang City, China's northwestern dryland. Bioaerosols were collected using a tethered balloon with a bioaerosol collector at 820 m above the ground (1,960 m above the sea level) around noon on August 17, 2007. The bioaerosols were cultured after the collection at Dunhuang Meteorological observatory. Two strains of molds were isolated using the Nutrient agar medium. About 400-bp 18S rRNA partial sequences were amplified by PCR and determined afterwards. The results of a homology search by 18S rRNA sequences of isolates in DNA databases (GenBank, DDBJ, and EMBL) and an observation of the form revealed that two bioaerosols in the convective mixed layer over Dunhuang City were Cladosporium sp. and Aspergillus sp.

• 한국인공지능학회지
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• 제8권1호
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• pp.7-9
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• 2020

In this paper, a study was conducted to find a self-diagnosis method to prevent the spread of COVID-19 based on machine learning. COVID-19 is an infectious disease caused by a newly discovered coronavirus. According to WHO(World Health Organization)'s situation report published on May 18th, 2020, COVID-19 has already affected 4,600,000 cases and 310,000 deaths globally and still increasing. The most severe problem of COVID-19 virus is that it spreads primarily through droplets of saliva or discharge from the nose when an infected person coughs or sneezes, which occurs in everyday life. And also, at this time, there are no specific vaccines or treatments for COVID-19. Because of the secure diffusion method and the absence of a vaccine, it is essential to self-diagnose or do a self-diagnosis questionnaire whenever possible. But self-diagnosing has too many questions, and ambiguous standards also take time. Therefore, in this study, using SVM(Support Vector Machine), Decision Tree and correlation analysis found two vital factors to predict the infection of the COVID-19 virus with an accuracy of 80%. Applying the result proposed in this paper, people can self-diagnose quickly to prevent COVID-19 and further prevent the spread of COVID-19.

• 소음진동
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• 제10권4호
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• pp.610-614
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• 2000

Cellular Automata(CA)s are used as a simple mathematical model to investigate self-organization in statistical mechanics, which are originally introduced by von Neumann and S. Ulam at the end of the 1940s. CAs provide a framework for a large class of discrete models with homogeneous interactions, which are characterized by the following fundamental properties: 1) CAs are dynamical systems in which space and time are discrete. 2) The systems consist of a regular grid of cells. 3) Each cell is characterized by a state taken from a finite set of states and updated synchronously in discrete time steps according to a local, identical interaction rule. 4) The state of a cell is determined by the previous states of a surrounding neighborhood of cells. A cellular automaton has been attracted wide interest in modeling physical phenomena, which are described generally, partial differential equations such as diffusion and wave propagation. This paper describes one and two-dimensional analysis of wave propagation phenomena modeled by CA, where the local interaction rules were derived referring to the Lattice Gas Model reported by Chen et al., and also including finite difference scheme. Modeling processes by using CA are discussed and the simulation results of wave propagation with one wave source are compared with that by finite difference method.

• 한국지역사회생활과학회지
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• 제25권1호
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• pp.39-49
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• 2014

This study identifies the necessity and importance of innovation in rural communities and highlights the role of rural revitalization support centers in facilitating the diffusion of community innovation. The study provides a literature review and employs the survey method to verify the arguments. There is an urgent need for rural communities to be distinct, attractive, and competitive in the wake of globalization. It is clear that they must recognize the need to facilitate innovation under growing trends toward trade liberalization, environment-oriented life styles, diversified consumer needs, and a knowledge-based society. The results provide support for the legitimacy of establishing rural revitalization support centers to help community leaders and local stakeholders develop their communities. More specifically, rural communities should employ R&D outcomes from diverse fields and capacity building by community members, leaders, and local governments to foster sustainable growth by overcoming limitations in spatial access and resources. The results suggest that rural revitalization support centers can be established as intermediary organizations that can be operated to facilitate community innovation in rural development. In addition, these centers should play key roles such as empowering communities, facilitating region-specific rural development policies, motivating R&D applications for rural development, encouraging rural development networks. Further, close attention should be paid to facilitate mutual learning by expanding networks and interactions between these centers.