• 제목/요약/키워드: Organ Donation

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Brain death and organ transplantation (뇌사와 심폐사 그리고 장기이식)

  • Nam, Sang-Ook
    • Clinical and Experimental Pediatrics
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    • v.52 no.8
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    • pp.856-861
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    • 2009
  • Cardiopulmonary arrest has long been accepted as an unquestionable definition of death. An advent of cardiopulmonary resuscitation and artificial ventilation along with the development of organ transplantation has prompted the emergence of the concept of brain death. The criteria for brain death are based mainly on the clinical examination of coma, apnea and total loss of brain stem function. Although organ transplantation by donor brain death has increased in Korea over recent years, there is still a substantial shortage of donor organs compared to the demand. Improvement of government policies and changes of social culture for organ donation are needed for the activation of organ transplantation by donor brain death. Pediatricians have an important role for the search of potential donors in cases of brain death and optimal medical care for successful organ transplantation.

Recent Trends in the Withdrawal of Life-Sustaining Treatment in Patients with Acute Cerebrovascular Disease : 2017-2021

  • Seung Hwan Kim;Ji Hwan Jang;Young Zoon Kim;Kyu Hong Kim;Taek Min Nam
    • Journal of Korean Neurosurgical Society
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    • v.67 no.1
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    • pp.73-83
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    • 2024
  • Objective : The Act on Life-Sustaining Treatment (LST) decisions for end-of-life patients has been effective since February 2018. An increasing number of patients and their families want to withhold or withdraw from LST when medical futility is expected. This study aimed to investigate the status of the Act on LST decisions for patients with acute cerebrovascular disease at a single hospital. Methods : Between January 2017 and December 2021, 227 patients with acute cerebrovascular diseases, including hemorrhagic stroke (n=184) and ischemic stroke (n=43), died at the hospital. The study period was divided into the periods before and after the Act. Results : The duration of hospitalization decreased after the Act was implemented compared to before (15.9±16.1 vs. 11.2±18.6 days, p=0.127). The rate of obtaining consent for the LST plan tended to increase after the Act (139/183 [76.0%] vs. 27/44 [61.4%], p=0.077). Notably, none of the patients made an LST decision independently. Ventilator withdrawal was more frequently performed after the Act than before (52/183 [28.4%] vs. 0/44 [0%], p<0.001). Conversely, the rate of organ donation decreased after the Act was implemented (5/183 [2.7%] vs. 6/44 [13.6%], p=0.008). Refusal to undergo surgery was more common after the Act was implemented than before (87/149 [58.4%] vs. 15/41 [36.6%], p=0.021) among the 190 patients who required surgery. Conclusion : After the Act on LST decisions was implemented, the rate of LST withdrawal increased in patients with acute cerebrovascular disease. However, the decision to withdraw LST was made by the patient's family rather than the patient themselves. After the execution of the Act, we also observed an increased rate of refusal to undergo surgery and a decreased rate of organ donation. The Act on LST decisions may reduce unnecessary treatments that prolong end-of-life processes without a curative effect. However, the widespread application of this law may also reduce beneficial treatments and contribute to a decline in organ donation.

Public's Attitude to Organ Transplants and Factors Influencing Attitudes (장기이식에 대한 일반인의 태도 및 영향요인)

  • Shon Young-Hee;Cho Chung-Min
    • Journal of Korean Academy of Fundamentals of Nursing
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    • v.9 no.2
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    • pp.279-287
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    • 2002
  • Purpose: This study was done to Identify attitude and factors influencing attitudes to organ transplants. Method: Study participants were 165 people over the age of 18 and living in Seoul. The instrument used for this study was the descriptive questionnaire developed by Ju (1995). Analysis of the data was done with SPSS Win 10.0 with descriptive statistics. t-test. ANOVA and stepwise multiple regression. Results : 1. The scores on attitude toward organ transplants ranged from 14 to 70. and had a mean score of 49.26. There were statistically significant differences in scores on attitude to organ transplants according to age (p= .03). marital status (p= 00), monthly income (p=.02) and experience of having education about organ transplants (p= .00). 2. The factors influencing attitudes to organ transplants were having the experience of education on transplants and marital status. These two variables explained 20.1% of the variance. 3. Reasons given for no written pledge to donate one's organs were 'fear on organ donation', 'not knowing the way of' how to do'. 'plan to give my organs to a family member when needed'. 'physical condition' and 'religious belief'. Conclusion: Experience with education for organ transplant and marital status were identified as important variables in attitudes to organ transplants.

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Young Adult Donor's Experiences of Living Donor Liver Transplantation (청년 생체 간이식 기증자의 경험)

  • Bang, Miseon;Shin, Haeyun;Ryu, Min;Kwon, Suhye
    • Journal of Korean Academy of Nursing
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    • v.51 no.1
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    • pp.105-118
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    • 2021
  • Purpose: This study aimed to explore young adult donors' experiences of living donor liver transplantation. Methods: A phenomenological research method was used. The participants were two women and six men. Data were collected through individual in-depth interviews from November 25th, 2019 to June 10th, 2020 and analyzed using Colaizzi's phenomenological method. Results: Five theme clusters extracted from the young adult donors' experiences were painful decision of a liver donation, the agony of both mind and body that overpowers youth, the bitter and bare face of reality that a young donor encounters, feeling the power of love that fills up the space of the organ removed, and liver donation becoming priming water for maturity. Conclusion: The results of this study provide a deeper understanding of the lives of young adult donors who have experienced unexpected difficulties as well as self growth from the donation. It is expected that the results can be of use for developing and applying customized nursing interventions for management before and after liver donation among young adult donors.

A Convergence Study on the Consciousness of Bio-medical Ethics of Dental Hygiene and Health Science related Majoring Students (치위생(학)과와 보건계열 대학생들의 생명 의료윤리 의식에 관한 융합연구)

  • Park, Young-Nam
    • Journal of Convergence for Information Technology
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    • v.9 no.10
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    • pp.227-233
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    • 2019
  • This study surveyed the dental hygiene and health science students in order to grasp the bioethics consciousness from June to July 2018 and to provide basic data for the development of the bioethics curriculum. Correlation between fetal right of life and artificial insemination awareness was significant in gender(r=0.241), religion(r=-0.176), and department(r=-0.160). Correlation between awareness of organ donation and organ transplantation was significant in grade(r=0.129), religion(r=-0.098), bio ethics educ ation(r=0.235). Correlation of euthanasia perception was significant in religion (r=0. 139), bioethics education(r=-0.157). As a result, To establish an ethical view that is desirable for health college students, Necessary to develop a curriculum and to sys tematically run education programs by analyzing the factors that affect biomedical ethics.

Extracorporeal Life Support in Organ Transplant Donors

  • Chang, Wonho
    • Journal of Chest Surgery
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    • v.51 no.5
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    • pp.328-332
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    • 2018
  • Background: Extracorporeal life support (ECLS) can be applied in brain-dead donors for organ perfusion before donation, thereby expanding the donor pool. The aim of this study was to examine the benefits and early clinical outcomes of ECLS for organ preservation. Methods: Between June 2012 and April 2017, 9 patients received ECLS with therapeutic intent or for organ preservation. The following data were collected: demographics, purpose and duration of ECLS, cause of death, dose of vasoactive drugs, and need for temporary dialysis before organ retrieval. The early clinical outcomes of recipients were studied, as well as survival and graft function at 1 month. Results: ECLS was initiated for extracorporeal cardiopulmonary resuscitation in 5 patients. The other patients needed ECLS due to hemodynamic deterioration during the assessment of brain death. We successfully retrieved 18 kidneys, 7 livers, and 1 heart from 9 donors. All organs were transplanted and none were discarded. Only 1 case of delayed kidney graft function was noted, and all 26 recipients were discharged without any significant complications. Conclusion: The benefits of protecting the vital organs of donors is significant, and ECLS for organ preservation can be widely used in the transplantation field.

A Bioethical Study of the Informed Consent for Organ Donor (장기공여를 위한 사전동의의 생의윤리학적 고찰)

  • Um, Young-Rhan;Han, Sung-Suk
    • Journal of Korean Academy of Nursing Administration
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    • v.4 no.2
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    • pp.475-487
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    • 1998
  • This is a study to search for the ethical basis for valid informed consent of organ donors. It is an admirable action that a person give his own body part or organ as a gift to another person. The organ for transplantation can be removed only when the donor consents voluntarily to donation. It is recently proposed as the need for organ transplantation is increased that organs can be harvested although the consent of deceased cannot be obtained. This may raise many moral issues because human beings all have an unalienable right to control their own bodies. The principle of autonomy is usually regarded as an ethical basis for informed consent. However, some people criticize that the principle of autonomy requires a person and his decision to be autonomous (but there are many patients who aren't autonomous due to their confusion or unconscious condition in a clinical situation). or this principle can foster indifference to patients needing help: thus respect for principles of care and beneficence is necessary. When we consider the complexity of making a decision about organ donation. the principle of autonomy should be replaced by the principle of respect for individual autonomy. as expressed by Childress (1990). This principle requires the care givers to respect the client's individual decisions. The elements of informed consent are threshold elements: competence to understand and decide. voluntariness in deciding: information elements: disclosure of material information. recommendation of a plan. understanding of disclosure and recommendation: and consent elements: decision in favor of a plan. authorization of the chosen plan. In cases of living donors. the elements of competence and voluntariness are more important than the others. So only an adult can give a recipient his own body part. but it should be forbidden to harvest from minors or protected adults (i.e. developmentally disabled person However. when organs are removed from a cadaver donor. we ought to respect the donor's decision. So we ought to try to seek donor cards or any documents expressing the donor's opinion about organ transplant. All health care givers ought to disclose donor information about organ transplantation clearly enough for the donor to understand it and to be able to weigh the harms and benefits. We are going to propose 'the subjective standard' as the ethical standard of disclosure. This standard will assure that patients have enough information to be able to decide autonomously from their own position. Care givers have to consider the method of disclosure because donors can be influenced by it positively or negatively, Establishment of the Hospital Committee is recommended. because medical professionals will have a chance to discuss the procedure of decision and the validity of harvesting a organ from a person.

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Psychosocial Pre-Transplant Assessment of Living Kidney Donors (생체 신장 이식 공여자에 대한 정신사회적 평가)

  • Ah Rah Lee;Myungjae Baik;Sang Min Lee;Won Sub Kang;Jin Kyung Park
    • Korean Journal of Psychosomatic Medicine
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    • v.31 no.2
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    • pp.43-49
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    • 2023
  • In Korea, the dependence on living donations is high due to the shortage of organs available for donation compared to the number of people waiting for transplants and the number of living organ donations continues to increase. In particular, the number of living-donor transplantations is high worldwide, highlighting the importance of pre-transplant psychosocial evaluation of living kidney donors. According to previous studies, when evaluating living organ donors before transplantation, it is crucial to determine whether the donor can give informed consent and be aware of the risks after surgery. Pre-transplant evaluation tests such as ELPAT living organ donor Psychological Assessment Tool (EPAT), Live Donor Assessment Tool (LDAT), Living Donation Expectancies Questionnaire (LDEQ), Minnesota Multiphasic Personality Inventory-2 questionnaire (MMPI-2) and Temperament and Character Inventory (TCI) are conducted for donors. After reviewing the literature on these pre-transplant psychosocial assessment tools, we will also look at legal considerations for living kidney donors in Korea and suggest an effective and essential pre-transplant screening evaluation method for living kidney transplant donors.

Factors Influencing Withdrawal of Life-Sustaining Treatment in Tertiary General Hospital Workers -Knowledge and Attitude of Organ Donation and Transplantation, Awareness of Death, Knowledge and Perception of Hospice Palliative Care- (상급종합병원근무자의 연명치료중단에 미치는 영향요인 -장기기증·이식의 지식 및 태도, 죽음에 대한 인식, 호스피스완화의료에 대한 지식 및 인식-)

  • Je, Nam Joo;Hwa, Jeong Seok
    • Journal of Hospice and Palliative Care
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    • v.21 no.3
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    • pp.92-103
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    • 2018
  • Purpose: This descriptive study was conducted to examine factors that affect hospital workers in their decision to withdraw from life-sustaining treatment, such as knowledge, attitude, and perception of organ donation, transplantation, death and hospice palliative care. Methods: A questionnaire was completed by 228 workers of a tertiary general hospital, and data were analyzed using t-test, ANOVA, and Pearson's correlation by using SPSS 21.0. Results: The subjects' knowledge of biomedical ethics awareness differed by age, education level, occupation, affiliated department, and biomedical ethics education. Their knowledge of brain death, organ donation and transplantation was positively correlated with attitudes toward tissue donation and transplantation, knowledge of hospice palliative care, and perception of hospice palliative care. Their attitudes toward tissue donation and transplantation were significantly correlated with knowledge of hospice palliative care, perception of hospice palliative care, and withdrawal of life-sustaining treatment. Their awareness of death was significantly correlated with knowledge of hospice palliative care, perception of hospice palliative care and withdrawal of life-sustaining treatment. The perception of hospice palliative care was significantly correlated with withdrawal of life-sustaining treatment. Factors associated with their withdrawal of life-sustaining treatment were work at the hospice ward (32.5%), attitudes toward tissue donation and transplantation and perception of hospice palliative care. Conclusion: This study has shown that work at the hospice ward, attitudes toward tissue donation and transplantation and perception of hospice palliative care were related to attitudes toward withdrawal of life-sustaining treatment. More research is needed to further develop various curriculums based on biomedical methods.