• 한국발생생물학회지:발생과생식
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• 제8권2호
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• pp.85-89
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• 2004

본 연구는 임신한 생쥐에 DEHP의 투여가 분만 후 생쥐의 번식기능과 태아의 성비에 미치는 영향을 검토하였다. 임신한 자성 생쥐에 DEHP을 투여한 후 임신 19일째에 임신한 자성의 체중, 태아의 체중, 태아수 및 태아성비를 조사한 결과, 실험개시시와 실험종료시 임신한 자성의 체중은 각 투여구간에 차이가 없었으며, 자${\cdot}$웅성태아의 체중, 평균 태아수 및 태아의 자${\cdot}$웅성 성비는 투여구간에 커다란 차이가 없었다. 임신기에 DEHP의 투여가 분만한 후 어미의 번식기관무게와 혈구화학치에 미치는 효과를 검사한 결과, 각 투여구간에 커다란 차이는 없었다. 임신기에 DEHP의 투여가 분만한 후 난소와 자궁의 조직에 미치는 영향을 조사한 결과, 난소에서는 모든 투여구간에 커다란 차이는 없었으나, 자궁에서는 0.5mg 투여구가 대조구에 비해 자궁내막층과 부종이 감소했으며, 1.0mg 투여구와 10.0mg 투여구는 일부에서 자궁내막층이 감소했지만 0.5mg 투여구에서의 감소보다는 적었다. 임신중인 생쥐에 저농도의 DEHP의 투여는 임신중인 모체와 태어난 자손의 번식 특성과 혈구화학치에 영향을 미치지 않았다.

• Journal of Trauma and Injury
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• 제34권1호
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• pp.3-12
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• 2021

Purpose: To evaluate the severity of trauma, many scoring systems and predictive models have been presented. The quick Sequential Organ Failure Assessment (qSOFA) is a simple scoring system based on vital signs, and we expect it to be easier to apply to trauma patients than other trauma assessment tools. Methods: This study was a cross-sectional study of trauma patients who visited the emergency department of Jeju National University Hospital. We excluded patients under the age of 18 years and unknown outcomes. We calculated the qSOFA, the Modified Early Warning Score (mEWS), Revised Trauma Score (RTS), and Injury Severity Score (ISS) based on patients' initial vital signs and assessments performed in the emergency department (ED). The primary outcome was mortality within 14 days of trauma. We analyzed qSOFA scores using multivariate logistic regression analysis and compared the predictive accuracy of these scoring systems using the area under the receiver operating characteristic curve (AUROC). Results: In total, 27,764 patients were analyzed. In the multivariate logistic regression analysis of the qSOFA, the adjusted odds ratios with 95% confidence interval (CI) for mortality relative to a qSOFA score of 0 were 27.82 (13.63-56.79) for a qSOFA score of 1, 373.31 (183.47-759.57) for a qSOFA score of 2, and 494.07 (143.75-1698.15) for a qSOFA score of 3. In the receiver operating characteristic (ROC) curve analysis for the qSOFA, mEWS, ISS, and RTS in predicting the outcomes, for mortality, the AUROC for the qSOFA (AUROC [95% CI]; 0.912 [0.871-0.952]) was significantly greater than those for the ISS (0.700 [0.608-0.793]) and RTS (0.160 [0.108-0.211]). Conclusions: The qSOFA was useful for predicting the prognosis of trauma patients evaluated in the ED.

• 한국가축번식학회지
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• 제26권1호
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• pp.53-59
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• 2002

웅성 생쥐에 자기장을 15일 동안 1일 5시간씩 60G의 강도로 노출시킨 결과, 정자농도는 대조구와 자기장 15일 처리구가 각각 25.1$\pm$6.5$\times$$10^{6}$$m\ell$와 15.7$\pm$5.3$\times$$10^{6}$$m\ell$로서 처리구가 대조구에 비하여 유의적으로 낮게 나타났다(P＜0.05). 생존율은 대조구와 자기장 15일 처리구가 각각 34.4%와 29.3%로서 처리구가 대조구에 비하여 낮게 나타났지만 유의적인 차이는 인정되지 않았다(P〉0.05). 기형율은 대조구와 자기장 15일 처리구가 각각 11.7%와 18.0%로서 처리구가 대조구에 비하여 유의적으로 높은 성적을 나타냈다(P〉0.05). 체중과 번식기관 무게는 대조구와 자기장 처리구간에 차이가 인정되지 않았다. 장기무게중 간, 신장은 대조구와 자기장 처리구간에 차이가 인정되지 않았으나, 비장은 대조구와 자기장 15일 처 리구가 각각 0.116g과 0.227g으로서 처리구가 대조구에 비하여 유의적으로 높게 나타났다(P＜0.05).

• 대한치과의사협회지
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• 제48권5호
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• pp.365-370
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• 2010

Herpes virus family is highly infectious to patients, their families and dentists. The diagnosis of herpes infection is based on the characteristic clinical appearance and the location of the lesions. Herpes Simplex Virus(HSV) usually acquired through direct contact with infected lesions or body fluids, and the prevalence of HSV infection increases progressively from childhood. Primary infections provoke herpetic gingivostomatis typically affects the tongue, lips, gingival, buccal mucosa and palate. Recurrent infections give rise to vesiculo-ulcerative lesions at vermilion border of lip(herpes labialis). In the form of chickenpox, Varicella Zoster Virus(VZV) usually is infected in childhood. VZV spreads in the affected primary afferent nerve to the skin and produces a vesicular rash and pain. Epstein-Barr Virus(EBV) infects B cells and cause infectious mononucleosis. Latent EBV infection has also been implicated in Burkitt lymphoma, nasopharyngeal carcinoma. Cytomegalovirus(CMV) is associated with immune-compromised patient such as organ transplantation and AIDS patients.

• The Journal of Korean Physical Therapy
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• 제11권2호
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• pp.5-9
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• 1999

The electromagnetic agent used in physical therapy rely far their effects on tissue heating and photo reaction of the body, Infrared has a thermal and analgesic effect, Ultra violet produces direct photo chemical reaction when it interacts with the body. Laser has broad effect on medicine, Ten ding Diancibo Pu (TDP) is in the infrared ray. The wave range is 20,000-250,000, as a far infrared. The effects of the TDP are number of white and red blued cell, capacity of animal immunization activity of enzyme in the organ and blood sugar density.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제32권1호
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• pp.65-68
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• 2006

Muscular involvement in Behcet's disease is rare manifestation in spite of basic characteristic that is vasculitis can invade multi-organ of the entire body. A few cases has been announced involving the lower extremities, the arm and generalized weakness. Like our case, myositis involving the masticatory muscles with clinically diagnosed Behcet's disease was presented with the magnetic resonance imaging (MRI) and the clinical findings, which is, not yet documented in the literature.

• Imaging Science in Dentistry
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• 제45권3호
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• pp.181-185
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• 2015

Numerous cases of enamel renal syndrome have been previously reported. Various terms, such as enamel renal syndrome, amelogenesis imperfecta and gingival fibromatosis syndrome, and enamel-renal-gingival syndrome, have been used for patients presenting with the dental phenotype characteristic of this condition, nephrocalcinosis or nephrolithiasis, and gingival findings. This report describes a case of amelogenesis imperfecta of the enamel agenesis variety with nephrolithiasis in a 21-year-old male patient who complained of small teeth. The imaging modalities employed were conventional radiography, cone-beam computed tomography, and renal sonography. Such cases are first encountered by dentists, as other organ or metabolic diseases are generally hidden. Hence, cases of amelogenesis imperfecta should be subjected to advanced diagnostic modalities, incorporating both dental and medical criteria, in order to facilitate comprehensive long-term management.

• 대한전자공학회:학술대회논문집
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• 대한전자공학회 2007년도 하계종합학술대회 논문집
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• pp.425-426
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• 2007

It is caused by characteristic differences when aligned the electrical aspect of the system with the idiosyncrasy of the human hearing organ. Considering such an issue, this thesis places its purpose in obtaining a favored sound which objectively analyzed and subjectively evaluated. Since a favored sound is different person to person, the research object is limited to peculiar areas in where similar cultural backgrounds are found. An average spectrum is extracted from the sound sources of music albums sold in the areas, and objectively utilized. This study searches for an approaching method in producing AV system to sell in a specific country.

• Journal of Genetic Medicine
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• 제18권1호
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• pp.70-74
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• 2021

Cohen-Gibson syndrome (CGS) was first reported by Cohen et al., who identified the mutation of the gene encoding the embryonic ectoderm development (EED) in a patient with phenotypes similar to Weaver syndrome. CGS manifests as an overgrowth and intellectual disability, in addition to the characteristic facial features and organ anomalies. CGS has been reported in only 11 unrelated patients since 2015. A girl aged 6 years and 3 months presented with seizures. She had macrosomia, a dysmorphic face, and intellectual disability. Her mother and younger sister and brother also had macrosomia, intellectual disability, and similar facial features; additionally, her mother experienced seizures and had an arachnoid cyst, while her siblings had valvar pulmonary stenosis. Whole-exome sequencing for the proband revealed a mutation of EED (c.581A>G, p.Asn194Ser), which was also verified in the mother and both siblings using Sanger sequencing. This is the first report of familial CGS.

• 한국콘텐츠학회논문지
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• 제16권2호
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• pp.387-397
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• 2016

본 연구의 목적은 실버세대를 대상으로 하는 그림동화책의 필요성과 특성을 학문적 고찰을 통해 실버세대를 위한 그림동화책의 디자인적 특성들을 실증적으로 제시한 것이다. 고령화 현상과 문헌정보학, 교육학, 문학치료학 등 문헌자료의 분석결과를 통해 그림동화책은 실버세대들의 심신건강에 도움이 된다는 결과를 얻게 되었지만 실버세대를 위한 동화책은 수요에 비해 부족한 것이 현실이다. 그러므로 실버세대를 위한 동화책 연구개발에 대한 이론적 근거가 절실하게 필요하다. 따라서 본 연구는 실버세대의 시각기관, 몸 기능, 심리적 요인 등 특성을 반영한 그림동화책의 개발이 필요함을 제언하면서 동시에 실버세대를 위한 동화책을 디자인 할 때 그림의 특징 요소 중 스토리내용, 그림(표현방법, 크기, 레이아웃, 구도, 색채), 타이포 등에서 실버세대들의 독서 장애에 대한 문제점을 해결하기 위한 실버세대의 특성에 맞춰진 세심한 주의가 필요함을 제시하였다. 또한 향후에는 실버세대를 대상으로 한 실증분석을 통해 실버세대를 위한 그림동화책의 구성에 적합한 디자인적 특성이 입체적인 분석 데이터를 연구함에 있어 선행 자료의 일부분으로 활용되길 기대한다.