• 제목/요약/키워드: Organ

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자궁경부암의 고선량률 근접치료시 장기묘사 방법에 따른 직장과 방광의 선량비교 분석 (Bladder And Rectum Dose Define 3D Treatment Planning for Cervix Cancer Brachtherapy Comparison of Dose-Volume Histograms for Organ Contour and Organ Wall Contour)

  • 김종원;김대현;최준용;원영진
    • 대한방사선기술학회지:방사선기술과학
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    • 제35권4호
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    • pp.327-333
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    • 2012
  • 직장과 방광 장기의 내부공간을 뺀 나머지 실질적 용적에 얼마큼의 방사선이 조사되는지를 묘사방법에 따라 직장과 방광의 볼륨에 따른 흡수선량을 dose-volume histogram(DVH)를 이용하여 선량을 비교 분석 하였다. 자궁경부암 환자 중 고선량률 근접치료기를 이용하여 치료 받는 13명(tandem and ovoid used 13명)을 대상으로 강내치료계획은 외부방사선치료(50.4 Gy)가 끝난 후 수립되었으며 모든 환자에 컴퓨터 단층촬영(computed tomography, CT) 모의치료가 시행되었고 치료계획장비는 PLATO BPS v13.7를 이용하여 3D plan을 하였다. 치료계획에서 직장, 방광의 organ outer wall contour(OOWC)와 organ wall contour(OWC)를 묘사 후 ICRU 38에 근거하여 A점에 100 %를 조사하는 치료계획을 수립하였다. 분석방법으로 치료계획장비의 Dose-Volume Histogram(DVH)을 이용하여 직장과 방광의 묘사방법에 따라 0.1 $cm^3$, 1 $cm^3$, 2 $cm^3$, 5 $cm^3$, 10 $cm^3$ 볼륨이 받는 선량을 비교분석 하였고, 장기의 평균볼륨, 최대볼륨, 최소볼륨을 비교하였다. 방광의 OOWC의 묘사방법에 따른 평균볼륨 202 $cm^3$이며, 최대볼륨은 457 $cm^3$, 최저볼륨은 90 $cm^3$를 나타내고 있으며, OWC의 묘사방법에서 평균볼륨은 35 $cm^3$, 최대볼륨은 66 $cm^3$, 최소볼륨은 20 $cm^3$의 결과를 나타내고 있으며, 방광의 OOWC와 OWC 볼륨에 대한 선량비율(organ outer dose/organ wall dose)은 0.1 $cm^3$에서는 $1.00{\pm}0.01$이고, 1 $cm^3$$1.03{\pm}0.03$, 2 $cm^3$$1.07{\pm}0.05$, 5 $cm^3$$1.22{\pm}0.08$, 10 $cm^3$$1.9{\pm}0.23$ 이다. 용적이 증가할수록 차이가 늘어나는 경향이 나타나고 있으며, 2 $cm^3$에서부터 OOWC 묘사방법의 선량과 OWC 묘사방법의 선량 차이가 늘어나는 것을 알 수 있다. 직장에서의 OOWC와 OWC 볼륨의 선량 차이는 0.1 $cm^3$에서는 $1.01{\pm}0.02$이고, 1 $cm^3$$1.03{\pm}0.04$, 2 $cm^3$에서는 $1.11{\pm}0.06$, 5 $cm^3$에서 $1.35{\pm}0.17$, 10 $cm^3$에서 $1.78{\pm}0.25$를 나타내고 있다. 마찬가지로 볼륨이 2 $cm^3$에서부터 OOWC의 묘사방법 선량과 OWC 묘사방법의 선량 차이가 늘어나는 것을 알 수 있다. 본 연구는 자궁경부암 환자의 고선량률 근접치료 시 방광과 직장의 볼륨 2 $cm^3$까지 받는 선량이 묘사방법에 따라 일정한 선량을 보이며 그 이상의 볼륨에서는 선량 차이가 증가 하였다. 따라서 임상적으로 나타나는 합병증인 천공과 출혈의 원인을 유추 할 수 있는 선량은 기존에 사용되는 묘사방법으로는 볼륨 2 $cm^3$까지 결과를 사용해야 될 것이다. 하지만 치료계획장비에 사용되는 OWC의 묘사방법이 기존에 묘사방법에 비해 3배~5배 이상의 시간이 소요가 되므로 치료계획장비의 묘사방법의 개선이 이루어진다면 정확한 선량평가 방법이 될 수 있을 것이다.

Ktc: Sprague-Dawley 랫드의 장기중량치의 자료분석 (Reference Values of Organ Weights in Sprague-Dawley Rats)

  • 강부현;김일환;김용범;김영희;이현숙;하창수
    • 한국수의병리학회지
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    • 제5권2호
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    • pp.39-42
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    • 2001
  • A reference range data base containing organ weight values on animals used in 4 week and 13 week toxicity tests is described. Data listed include the values of minimum, maximum, mean and standard deviation for each of the following organ weights. Organs: Brain, heart, liver, spleen, kidney, adrenal gland, testis, ovary. This study was undertaken to determine organ weight reference values of Ktc: SD rats

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A Review of Organ Dose Calculation Tools for Patients Undergoing Computed Tomography Scans

  • Lee, Choonsik
    • Journal of Radiation Protection and Research
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    • 제46권4호
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    • pp.151-159
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    • 2021
  • Background: Computed tomography (CT) is one of the crucial diagnostic tools in modern medicine. However, careful monitoring of radiation dose for CT patients is essential since the procedure involves ionizing radiation, a known carcinogen. Materials and Methods: The most desirable CT dose descriptor for risk analysis is the organ absorbed dose. A variety of CT organ dose calculators currently available were reviewed in this article. Results and Discussion: Key common elements included in CT dose calculators were discussed and compared, such as computational human phantoms, CT scanner models, organ dose database, effective dose calculation methods, tube current modulation modeling, and user interface platforms. Conclusion: It is envisioned that more research needs to be conducted to more accurately map CT coverage on computational human phantoms, to automatically segment organs and tissues for patient-specific dose calculations, and to accurately estimate radiation dose in the cone beam computed tomography process during image-guided radiation therapy.

일 지역 간호사의 뇌사자 장기기증에 대한 태도 조사 (Attitudes on Organ Donation in Brain Dead Donors of Staff Nurses)

  • 송영신;이미영
    • 한국간호교육학회지
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    • 제14권2호
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    • pp.216-223
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    • 2008
  • Purpose: The purpose of this study was to discover attitudes toward organ donation in brain dead donors and nursing ethical values of staff nurses. Method: The subjects were 196 nurses with direct patient care in a university hospital. Data collection was carried out for one month in September, 2008 using structured questionnaire. The data were analyzed using frequency, percentage, mean and standards deviation, ANOVA and Pearson's Correlation with SPSS program. Result: The mean score of a positive attitude toward organ donation in brain dead donors was 3.59 points, and a negative attitude score was 3.02 points. The mean score of nursing ethical value was 3.05 points. The age and the length of career had a reverse correlation with a negative attitude toward organ donation. Nursing ethical values had a positive correlation with a negative attitude toward organ donation. Conclusion: It is necessary to increase understanding and recognition of brain death organs donation in the nurses who participate in direct patient care so as to help facilitate organ donation.

한우 및 재래산양 서비기관의 형태학적 연구 (Morphological studies on the vomeronasal organ of Korean native cattle and Korean native goats)

  • 모기철
    • 대한수의학회지
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    • 제29권3호
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    • pp.231-237
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    • 1989
  • Morphological features of the vomeronasal organ of both Korean native cattle and Korean native goat were studied by gross, microscopic and histochemical examinations. Anatomical characteristics of the vomeronasl organ were similar in both Korean native cattle and Korean native goats. The vomeronasal organ is a tubular structure situated bilaterally at the base of the nasal septum, and enclosed by hyaline cartilage. Its lumen is semilunar to crescent in transverse sections. It join with the incisive duct through narrow duct. The lumen of the vomeronasal organ is lined with sensory and respiratory epithelia. The distribution pattern of vomeronasal mucosal epithelia varied by the position. In the anterior portion joining with nasal cavity, the lumen is lined with only respiratory epitheliu. In the middle portion, sensory epithelium appeared on the medial side, and respiratory epithelium on the lateral side. In the posterior, it is lined with sensory epithelium on the ventral side and lined with respiratory epithelium on the dorsal side. The vomeronasal gland composed of mucous and serous acini are distributed in the lamina propria under the respiratory epithelium, where venous sinuses are also well developed.

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복부 컴퓨터단층촬영 영상에서 다중 아틀라스 기반 위치적 정보를 사용한 계층적 장기 분할 (Hierarchical Organ Segmentation using Location Information based on Multi-atlas in Abdominal CT Images)

  • 김현진;김현아;이한상;홍헬렌
    • 한국멀티미디어학회논문지
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    • 제19권12호
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    • pp.1960-1969
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    • 2016
  • In this paper, we propose an automatic hierarchical organ segmentation method on abdominal CT images. First, similar atlases are selected using bone-based similarity registration and similarity of liver, kidney, and pancreas area. Second, each abdominal organ is roughly segmented using image-based similarity registration and intensity-based locally weighted voting. Finally, the segmented abdominal organ is refined using mask-based affine registration and intensity-based locally weighted voting. Especially, gallbladder and pancreas are hierarchically refined using location information of neighbor organs such as liver, left kidney and spleen. Our method was tested on a dataset of 12 portal-venous phase CT data. The average DSC of total organs was $90.47{\pm}1.70%$. Our method can be used for patient-specific abdominal organ segmentation for rehearsal of laparoscopic surgery.

미혼여성의 월경용품 사용현황과 생식기 위생관리 정도 (Status of Use of Menstrual Hygiene Products and Genital Organ Hygiene Management in Unmarried Women)

  • 김혜진;최소영
    • 여성건강간호학회지
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    • 제24권3호
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    • pp.265-275
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    • 2018
  • Purpose: The purpose of this study was to investigate the status of use of menstrual hygiene products and genital organ hygiene management in unmarried women. Methods: Data from 161 unmarried women were used for analysis. The instruments consisted of self-reported questionnaires that included 40 items: 20 on General Characteristics & Sexual Health Related Characteristics, 8 on Using Status of Menstrual Hygiene Products, 12 on Genital Organ Hygiene Management. Results: The subjects used disposable sanitary napkin as the most frequently but the satisfaction was low, while the use of reusable sanitary napkin and tampons were few, but satisfaction was high. Sixty-seven percent of the unmarried women had sex experience, and more than 60% experienced abnormal symptoms in the genital organ. There was a significant difference in genital organ hygiene management according to sex experience. Among subjects of this study, 44.1% wanted to use menstrual cup, and 98.8% wanted to have education for their menstrual hygiene products. Conclusion: Based on results of this study, a nationwide survey of the demand for menstrual hygiene products used by Korean women is needed, it is necessary to educate about the proper use of menstrual hygiene products and genital organ hygiene management.

뇌사자 장기이식에 대한 수술실 간호사의 태도와 삶의 의미가 간호윤리 가치에 미치는 영향 (Operation Room Nurses' Ethical Value regarding Their Attitude and Meaning of Life about Organ Transplantation in Brain Death)

  • 서형은;김미영
    • 성인간호학회지
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    • 제28권4호
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    • pp.355-366
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    • 2016
  • Purpose: The purpose of study was to describe operation room nurses' ethical values in relationship to the attitude and meaning of life toward organ transplantation in brain death. Methods: This study used a descriptive correlational survey design. Participants were 174 nurses who had attended to organ transplantation surgery in brain death more than once. Data were collected from September 1 to 11, 2015 and were analyzed using independent t-test, ANOVA, $Scheff{\acute{e}}$ test, Pearson's correlation coefficients, and hierarchical multiple regression with SPSS 22.0. Results: Educational level, attitude on organ transplantation in brain death, and meaning of life were significant variables predicting the level of nursing ethical value, accounting for 82.6% of the variability. Conclusion: Continued education and self-development programs should be encouraged for operating room nurses to establish professional nursing ethics as well as positive meaning of life and attitude toward the organ transplantation in brain death.

Fi'bricola seoulenis 조직융해구의 투사전자현미경 소견 (Transmission electron microscopic findings of the tribocytic organ of Fibricola seoulensis)

  • 송호복
    • Parasites, Hosts and Diseases
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    • 제31권4호
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    • pp.315-320
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    • 1993
  • Fibricola seoulensis 조직융해구(tribocytic organ)의 미세구조를 알기 위하여, 전자현미경으로 관찰하였다. 조직응해구의 표피에서 미세응모가 관찰되었다. 조직융해구에는 3가지 형태의 세포들이 관찰되는 데, 첫째는 방추형이고, 핵 및 원형질이 전자밀도가 낮고, 원형질내 직경 $0.1-0.2{\;}\mu\textrm{m}$의 과립이 소수 관찰된다 둘째는 방추형이고, 핵 및 원형질이 전자밀도가 높고, 직경 $0.1-0.2{\;}\mu\textrm{m}$의 미립자로 구성된 과립을 포함한다 셋째는 원형질이 전자밀도가 높고, 직경 $0.3-1.2{\;}\mu\textrm{m}$의 과립을 다수 포함한다. 위의 세포들 중, 첫째와 둘째 세포는 표피세포로, 셋째는 조직응해구의 특 이 분비세포로 추정한다. 이것은 조직융해구의 분비 기능을 설명할 수 있는 또 다른 소견이라고 할 수 있다.

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