• Asian Pacific Journal of Cancer Prevention
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• 제13권10호
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• pp.5251-5255
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• 2012

Background and Aim: Although the functional consequences of MDR-1 polymorphisms have been the subject of numerous studies, to the best to our knowledge, associations with clinical side effects of anticancer drugs have yet to be assessed. Our aim was to clarify any role of the C3435T polymorphism of the MDR1 gene in oral mucositis and its relation with elevated reactive oxygen species (ROS) levels, in children with acute lymphoblastic leukemia (ALL). Materials and Methods: The distribution of the MDR-1 C3435T polymorphism in 47 patients with ALL was determined by RFLP and compared with that of 68 healthy controls. Results: There were no association in distribution of genotypes of MDR-1 C3435T polymorphism and the risk of ALL. Oral mucositis were detected in 78.7% (n=37) of the patients and significantly related to the MDR-1 CT genotype (p=0.042), as confirmed by logistic regression analysis. Conclusion: Our preliminary data suggest that children carrying the CT genotype are more prone to develop oral mucositis, which might mean that the heterozygous genotype leads to accumulation of more reactive oxygen species. Since a limited number of patients was investigated, further studies are needed to confirm these findings.

• 산업융합연구
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• 제21권2호
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• pp.73-77
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• 2023

본 논문연구는 20-40대 성인을 대상으로 흡연 유.무에 따른 구강환경 변화에 관한 지식수준을 파악하여 성인에 대한 구강보건교육 시 치주질환과 흡연과의 연관성 및 금연에 관한 교육 병행의 중요성에 대한 기초 자료로 활용하고자 실시되었다. 2022년 8월과 9월에 걸쳐 편의표본 추출된 대상 500명에게 자기기입식 설문조사를 하였고, 수집된 자료는 SPSS 29.0 프로그램을 이용하여 분석하였다. 주관적인 구강상태 분석에서 비흡연자 가운데 매우 좋거나 좋다고 생각한 비율은 65.4%, 흡연자 그룹은 59.0%를 보였다. 또한, 비흡연자와 흡연자 그룹 모두에서 비흡연자의 청결도가 더 높을 것으로 생각한다는 답변이 가장 많았다. 금연교육을 받아본 적이 있느냐는 질문에 비흡연자 그룹의 63.9%, 흡연자 그룹의 76.1%가 '있다'라고 답하였다. '흡연 유무에 따라 구강환경에 변화를 보인다.'는 교육은 비흡연자군에서는 '없다'가, 흡연자군에서는 '있다'가 각각 높게 나타났다. 이와 같은 결과로 구강보건교육시 흡연과의 연관성 및 예방을 위한 구체적이고 적극적인 교육방법이 수반되어야 할 것으로 생각된다.

• 한국치위생학회지
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• 제9권2호
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• pp.125-136
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• 2009

The purpose of this study was to investigate the recognition of the infection routes, symptoms and treatments of HBV by students of health-related departments so as to help students learn correct knowledge about hepatitis B and provide the basic data for establishment of oral health policies to prevent hepatitis B and improve the quality of infection management. For the subjects of this study, 666 students of health-related departments and other departments of universities in Daegu City, Gyeongbuk Province were arbitrarily chosen and given a questionnaire. Then the questionnaires collected between October 1st and 31st, 2007 were analyzed. Major findings from this study are summarized below. 1. Regarding general characteristics of the subjects, 311 were students of health-related departments and 355 were students of other departments. 55.9% of the health-related department students and 49.0% of the other department students received immunization against hepatitis. 36.0% of the health-related department students and 31.6% of the other department students had antibodies. 2. Regarding the recognition of the infection routes of HBV, the right answer "Infected through placenta" was chosen by more juniors(94.4%), sophomores(93.8%) and freshmen(74.1%) of health-related departments than other students in this order (P<0.05). The answer "Infected through sexual intercourse" was chosen by the highest percentage(75.0%) of juniors followed by freshmen(69.2%) and sophomores(31.9%) (P<0.05). 3. The percentages of health-related department students who knew that "HBV can develop into hepatic cirrhosis or liver cirrhosis were the highest among juniors(88.9%), freshmen(87.7%) and sophomores(68.8%) in this order(P<0.05). Among the other department students, the percentages of right answers to the question "Acute HBV infection shows jaundice" were the highest among juniors(75.0%), sophomores(74.8%) and freshmen(58.7%)(P<0.05).

• East Asian mathematical journal
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• 제29권2호
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• pp.109-135
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• 2013

The purpose of the study was to investigate the reality of middle school mathematics teachers' subject matter knowledge for teaching mathematical conjecture and justification. Data in the study were collected through interviewing nine Chinese and ten Korean middle school mathematics teachers. The teachers responded to the question that was designed in the form of a scenario that presents a teaching task related to a geometrical topic. The teachers' oral responses were audiotaped and transcribed, and their written notes were collected. The results of the study were compared to the analysis of American and Chinese elementary and secondary teachers' responses to the same task in Ball (1988) and Ma (1999). The findings of the study suggested that teachers' approaches to explaining and demonstrating a mathematical topic were significantly influenced by their knowledge of learners and knowledge of the curriculum they teach. One of the practical implications of the study is that teachers should recognize the advantages of learning the conceptual structure of a mathematical topic. It allows the teachers to have the flexibility to come up with meaningful mathematical approaches to teaching the topic, which are comprehensible to the learners whatever the grade levels they teach, rather than rule-based algorithms.

• 한국융합학회논문지
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• 제10권6호
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• pp.59-64
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• 2019

본 연구는 구강관리용품 중 가장 대표적인 칫솔과 치약에서 이용자가 얻고자 하는 관련검색어를 통하여 이용자가 기대하는 선택정보를 구글 트렌드를 활용, 분석하여 이를 구강관리용품에 대한 교육의 기초자료로 제공하고자 한다. 구글 트렌드에서 제공하는 최초 시점인 2006년부터 2018년 현재(9월)까지의 시기에서 영문 Toothbrush와 Toothpaste를 검색한 뒤 인기순으로 정렬하여 노출되는 관련 검색어 각 25개 총325개의 검색어를 연도별로 수집하였다. 그 후 이용자가 기대하는 검색기능을 파악하는 검색어 세부분석방법과 빅데이터 프로그램 넷마이너를 활용한 단어 네트워크 분석의 두가지 방법으로 분석하였다. 연구 결과 전 세계적으로 Toothbrush에 대하여 브랜드에 대한 기대와 관심이 높았으며 Toothpaste에 대하여 치약의 기능에 대한 기대와 관심이 높았다. 이를 통해 구강교육의 동기부여를 높이기 위해 칫솔은 브랜드, 치약은 치약의 기능에 대한 지식과 정보를 활용하고 제공함으로써 환자의 흥미를 높이는 것이 효과적으로 판단된다.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제42권1호
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• pp.13-19
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• 2016

Objectives: As the craniofacial and neck regions are prime areas of injury in bear attacks, the careful management of soft and hard tissue injuries and selection of reconstructive options is of the utmost importance. This study will review the incidence and patterns of bear mauling in eastern India reported to our department and the various modalities used for their treatment over a period of 7 years. It also documents the risks of infection in bear mauling cases and the complications that have occurred. Materials and Methods: Twenty cases were treated over the study period. Cases were evaluated for soft and hard tissue injuries including tissue loss and corresponding management in the craniofacial region. Cases were also evaluated for other associated injuries, organ damage and related complications. Results: Various modalities of treatment were used for the management of victims, ranging from simple primary repairs to free tissue transfers. Simple primary repairs were done in 75% of cases, while the management of the injured victims required reconstruction by local, regional or distant flaps in 25%. Free tissue transfers were performed in 15% of cases, and no cases of wound infection were detected in the course of treatment. Conclusion: Knowledge of various reconstructive techniques is essential for managing maxillofacial injuries in bear mauling cases. Modern reconstructive procedures like free tissue transfer are reliable options for reconstruction with minimal co-morbidity and dramatic improvement in treatment outcomes.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제34권4호
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• pp.475-479
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• 2008

Aim: The aim of this study was to investigate the arterial arcade of maxillary sinus by determining the distance between the alveolar crest and the inferior border of the vessels in Korean population. Materials and methods: 76 patients and 87 available sinuses were determined by CT scan (Implagraphy, Vatech, Seoul, Korea). The distance between alveolar crest and inferior border of the vessel was determined considering the tooth area of posterior maxilla. Results: The lowest distance was observed on first molar area and the average distance is 16.9 mm. Discussions: it is important in sinus lift surgery that the vessels not to be damaged and that the anastomosis is situated in the lateral wall of maxillary sinus, which has to be exposed to gain access to the maxillary sinus. The knowledge of arterial arcade of maxillary sinus is important to perform the sinus floor elevation procedure effectively.

• 대한구순구개열학회지
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• 제11권2호
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• pp.49-58
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• 2008

The development of fetal surgery has led to promising options for many congenital malformations, such as congenital diaphragmatic hernia (CDH), obstructive uropathy, twin-to-twin transfusion syndrome (TTTS), and sacrococcygeal teratoma. However, preterm labor (PTL) and premature rupture of membranes continue to be uniquitous risks for both mother and fetus. To reduce maternal morbidity and the risk of prematurity, minimal access techniques were developed and are increasingly employed recently. Lift-threatening diseases as well as severely disabling but not life-threatening conditions are potentially amenable to treatment. Recently, improvement of video-endoscopic technology has boosted the development of operative techniques for feto-endoscopic surgery, which has been demonstrated to be less invasive than the open approach. Fetal surgery for repair of cleft lip and palate, a congenital anomaly which is not life threatening, is inappropriate until such time that the benefits are shown to outweigh the risks of both the procedure itself and preterm delivery. Further animal studies will be needed before intrauterine surgery for humans should be considered. For the better understanding of recent techniques and complications associated with fetal intervention of congenital facial defect patients, we reviewed recent related articles about the current knowledge and new perspectives of experimental fetal fetal surgery in the cleft lip and palate defects.

• 보건의료산업학회지
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• 제7권3호
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• pp.251-260
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• 2013

The purpose of this study was to make a comparative analysis of dental question and answer in portal sites. To achieve this, 4,212 questions were used for final analysis after connecting to Naver, Daum and Nate, which take first, second and third place in rank information of all sites at Rankey.com, to search dental information by keyword from January to late March. The results are as follows. Naver was the highest as a portal of Internet search engines. Questions on the use of dental clinics, the quality of dental services and the offer of dental services by types of dental clinics were very important. Dental clinics had to give dental patients customized services and information to please them through dental services and dental information services on the Internet, and questions and answers on this were increasing very explosively. Consequently, Dental clinics will have to give Internet users and health- and disease-related data searchers distinctive professional services by inquiring into factors affecting portal search and factors affecting health- and disease-related search, respectively.

• 한방비만학회지
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• 제11권2호
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• pp.41-68
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• 2011

Objectives: After organizing segmentations related to obesity from classics and each studies, we would like to examine the value of wild ginseng, bovis calculus, ursi fel and moschus as a obesity medicine. Methods: We found out 4 drugs which are wild ginseng, bovis calculus, ursi fel and moschus from the classics, such as "Shin-Nong-Bon-Cho-Kyung", "Myoung-Eui-Byul-Lok", "Bon-Cho-Gang-Mok", "Bon-Cho-Jong-Shin", "Bon-Cho-Bi-Yo", "Bon-Cho-Gu-Jin" and "Deuk-Bae-Bon-Cho", we searched websites such as RISS, Korean traditional knowledge portal, the society of Korean medicine for obesity research, Korean pharmacopuncture institute, the Korean academy of oriental rehabilitation medicine and Korean acupuncture & moxibustion society as well. Results: 1. We couldn't find the contents related to the efficacy of improving obesity through wild ginseng, bovis calculus, ursi fel and moschus from the classics. 2. Wild ginseng had a study dealing with the efficacy of anticancer, obesity, toxicity, immunity, sulfation, diabetes, plasma proteins, depression, hypertension, endometriosis and hair loss. Especially among 6 studies related to obesity, apart from the study that treated extract of wild ginseng directly to the cell or oral administration to the animals, also have studies that had an efficacy of improving obesity through injecting pharmacopuncture to acupuncture point and vein, etc. 3. Bovis calculus had a study about efficacy related to arthritis, liver, inflammation of cornea, obesity, anticancer, immunity, antacid, heart, lumbar pain, hypertension, toxicity, a digestive organ and sasang constitution, especially in case of obesity, had each studies about oral administration of complex prescription and about cell unit experiment of pharmacopuncture. 4. Ursi fel had a study about efficacy related to liver, arthritis, inflammation of cornea, immunity, obesity, anticancer, antacid, lumbar pain, digestive organ, toxicity, cell protection, skin ailment, etc. Especially in case of obesity, had each studies about oral administration of animal experiment and about cell unit experiment of pharmacopuncture. 5. Moschus had a study about efficacy related to liver, the central nervous system, arthritis, inflammation of cornea, immunity, obesity, anticancer, hypertension, heart, lumbar pain, etc. Especially in case of obesity, had one study about oral administration of complex prescription. Conclusion: Through the result of probability as a obesity medicine of wild ginseng, bovis calculus, ursi fel and moschus, we could identify the possibility of each drug as a obesity medicine. Also in the future, it is considered that studies about one or complex prescription and pharmacopuncture as a obesity medicine will be needed.