• 대한치과의사협회지
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• 제56권10호
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• pp.548-554
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• 2018

Choristoma is a growth of normal tissue that occurs at an abnormal region. In the oral cavity, osseous choristoma that has a normal bone feature mainly has been appeared. It is mainly occurred on the tongue. So, It can be found in dental practice or in discomfort in the mouth. Osseous choristoma in the oral cavity is extremely rare. But It can be treated excisional biopsy under local anesthesia. The prognosis is very good. This case is a report of osseous choristoma on the dorsal surface of the tongue. A 17-year-old female patient presented with a foreign body sensation of the tongue. A diameter of the mass is 0.7cm, and there is no pain. Panoramic radiographs showed a radiopaque image in the form of a double image. An excisional biopsy was performed and diagnosed as an osseous choristoma. 12 months after the resection, there were no signs of recurrence. Intraoral osseous choristoma is very rare, but it is clinically very simple and can be found in dental radiographs. We present this case because of Dentists who examine the oral cavity of the patient can easily diagnose the lesion and treat it by simple resection.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제42권4호
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• pp.221-226
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• 2016

Spindle cell carcinoma (SpCC) is referred to as a variant of oral squamous cell carcinoma. It is also known as "sarcomatoid squamous cell carcinoma" because it consists of normal squamous carcinoma cells with spindle-shaped cells that appear similar to a sarcoma. The term, "second primary tumor" (SPT) or "double primary tumor", is proposed for a second tumor that develops independently from the first. SPTs can present as either synchronous or metachronous lesions. Synchronous SPTs are defined as tumors occurring simultaneously or within 6 months after the first tumor. The patient in this case, whose primary tumor was in the tongue, was diagnosed with SpCC with metastases to both neck lymph nodes. This case also exhibited a second primary cancer as a synchronous lesion in the thyroid gland, which is uncommon. All carcinomas, both in the tongue and thyroid gland, were removed surgically, and especially in the tongue, an anterolateral thigh free flap was performed successfully to replace the defect.

• 대한치과기공학회지
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• 제36권3호
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• pp.187-196
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• 2014

Purpose: This study aims to examine correlation between temporomandibular disorder and oral habits that have been known to cause temporomandibular disorder with both male and female undergraduates. Methods: To figure out correlation between temporomandibular disorder and oral habits, a survey was conducted to 500 students of two universities located in Daegu Metropolitan City and Gyeongsangbuk-do, and excluding the ones unreliably answered or indicating errors, total 427 (85.4%) out of 500 questionnaire sheets were used for final analysis. Results: Female students showed higher prevalence rates than male students in temporomandibular joint pain and temporomandibular joint clicking, and students having the lip biting habit, tongue thrust habit, or bruxism habit indicated a higher prevalence rate of temporomandibular joint pain than normal students. Also, students having the tongue thrust habit indicated a significantly higher prevalence rate of temporomandibular joint clicking than normal students not having it. And about trismus, students having the bruxism habit showed a significantly higher prevalence rate than normal students not having it. Conclusion: The findings imply that oral habits like lip biting, tongue thrust, or bruxism are closely related with temporomandibular joint pain, tongue thrust influences temporomandibular joint clicking, and bruxism does affect trismus.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제46권2호
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• pp.99-107
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• 2020

Objectives: We accessed the various clinico-histopathological factors, and their association with occult metastasis (OM) in oral tongue squamous cell carcinoma (OTSCC). Materials and Methods: One hundred-nine patients with OTSCC were divided into the elective neck dissection (END) group and the watchful waiting (WW) group. Age, sex, T-stage, depth of invasion and differentiation were evaluated to determine the correlation between clinico-histopathological factors and OM. For immunohistochemical analysis, paraffin-embedded blocks of 41 OTSCC specimens were examined with antibodies (VEGF-c, c-Met, and ROR1). Results: The group with tumor thickness of oral tongue cancer ≥3 mm had higher incidence of OM than those with a thickness of <3 mm. The depth of invasion was statistically correlated with OM (P=0.022). Immunohistochemical analysis showed that high expression of VEGF-c (P=0.043), c-Met (P=0.009), and ROR-1 (P=0.003) were statistically correlated with OM. Conclusion: The analysis of these clinico-histopathological and immunohistochemical factors can help to determine neck dissection in clinically negative (cN0) patients.

• Asian Pacific Journal of Cancer Prevention
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• 제15권5호
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• pp.2225-2229
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• 2014

Background: Carcinoma of the tongue is the most common intra-oral malignancy in Western countries. Incidence and mortality rates have increased in recent years, and survival has not improved. This study aimed to determine etiologic factors for tongue cancer with age-sex matched case-control data. Materials and Methods: 47 patients with carcinoma of the tongue referred to our oral medicine clinic between years 2005-2006 were analyzed and compared with control group data. The medical records, including family history of cancer, dental trauma, and history of abuse of alcohol and tobacco products was recorded for all subjects. Chi square comparison tests and linear regression analysis were performed using the SPSS program for statistics. Results: Patient and randomly selected control groups each consisted of 30 male and 17 female subjects with mean ages 53.2 (${\pm}12.6$) and 52.6 (${\pm}11.5$) years respectively. Smoking and alcohol abuse proportions were significantly higher in the patient group (p=0.0001, p<0.0001 respectively). Chronic mechanical trauma was observed in 44.7% of the patients and 17.0% of the control group (p=0.004). Similarly, family history of cancer of any type (for the first degree relatives) was found to be more common in the patient group (p=0.009). On regression analysis, alcohol abuse, family history of cancer, smoking, chronic mechanical traumas appeared as significant etiologic factors (p=0.0001). Conclusions: We believe that field cancerization may become evident in oral and oropharyngeal mucosa with multiple steps of molecular changes starting from the first sign of dysplasia with chronic exposure to etiological factors. Chronic trauma cases need particular attention to search for very early signs of cancer.

• Journal of Oral Medicine and Pain
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• 제20권2호
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• pp.449-459
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• 1995

To investigate the relationship between recurrent aphthous ulcer and oral mucosal keratinization, exfoliative cytology in buccal mucosa, lip mucosa, tongue mucosa were performed on 25 recurrent aphthous ulcer patients and 25 controls whose age ranged from 10 to 65. Keratinization cell ratio was then measured. The results were as follows : 1. Yellow cell ratio in the control group was more than that in the patient group in buccal mucosa, lip mucosa, tongue mucosa. Red cell ratio in the control group was more than that in the patient group in lip mucosa. Blue cell ratio in the patient group was more than that in control group in all regions( p(0.01) 2. In the comparison by sex, the patient group showed no significant difference in all site but, the control group showed different results according to the site; males were more than females in yellow cell, but less than females in red cell Females were more than males in yellow cell, but less than males in red cell. 3. In the comparison by age, patient group showed no significant difference in all site, but the control group showed significantly high yellow cell ratio in buccal and tongue mucosa over the age of 50. In conclusion, there was close relationship between recurrent aphthous ulcer and decreased oral mucosal keratinization. In other words, reduced oral mucosal keratinization must be recommended for prevention of recurrent aphthous ulcer.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제33권3호
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• pp.260-262
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• 2007

Nearly 45% of all neurilemmoma occur in the head and neck area, but only 1% have an intraoral origin. The authors report two cases of uncommon neurilemmoma of the tongue. Both of them presented with a mass on the lateral border of the tongue, which was noted several days before. The lesions of tongue appeared as smooth-surfaced, well-circumscribed mass. They were excised under general anesthesia and diagnosed as neurilemmoma on histopathologic examination.

• 대한기관식도과학회지
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• 제19권1호
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• pp.28-30
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• 2013

Foreign bodies in the oral cavity and pharyngolarynx are frequently observed accidental cases in the otolaryngological fields. Most foreign bodies can be recognized and removable with the manipulation of endoscopes and various instruments. However, foreign bodies that penetrate the oral cavity and oropharynx to appear as a tongue mass are rare. Therefore, such cases easily can be misconceived as tongue tumor at first, so it must involve a more thorough search utilizing such aids as computed tomography. Depending on their location and size, their removal may involve surgical intervention. The authors experienced such a rare case of an elderly male patient, presenting as tongue mass. We hereby report this case along with the relevant literature.

• Journal of Oral Medicine and Pain
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• 제34권3호
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• pp.247-256
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• 2009

코골이와 수면무호흡증은 대부분 상기도의 인두부위의 폐쇄에 의해 발생되므로, 이 부위의 폐쇄를 방지하기 위해 혀나 하악을 전방으로 이동시키는 다양한 구강내 장치가 코골이 및 수면무호흡증의 치료에 사용되고 있다. 본 연구는 세 종류의 코골이장치 즉, 하악전방이동장치(mandibular advancement appliance, MAA), 혀견인장치(tongue retaining appliance, TRA), 하악-혀전방이동장치(mandibular advancement-tongue retaining appliance, MATRA )가 구인두와 하인두 공간을 어떻게 변화시키는지를 비교하고자 하였다. Class I 교합을 갖고 코골이 및 수면무호흡증의 증상이 없으며 체질량지수 (BMI)가 정상인 남성 9명을 대상으로 상기 세종류의 코골이장치를 제작하였으며, 이때 MAA, MATRA의 하악전방이동량은 5mm로 TRA, MATRA의 혀전방이동량은 10-20mm로 설정하였다. 그리고, 코골이장치를 장착하지 않은 CO상태와 MAA, TRA, MATRA를 장착한 상태에서 측모두부 규격방사선사진을 촬영한 후, 구인두와 하인두 공간, 두경부 자세, 연구개와 설골의 위치와 관련된 20가지 측정항목에 대해 통계분석을 시행하였다. 분석결과 MAA, TRA, MATRA 모두 상부 구인두 공간을 유의성 있게 증가시켰으나, MATRA 만이 하부 구인두 공간을 유의성 있게 증가시켰다. 이러한 결과는 코골이와 수면무호흡증을 개선시키는데 있어 MATRA가 MAA와 TRA에 비해 효과적일 수 있음을 시사한다.

• Journal of Oral Medicine and Pain
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• 제47권3호
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• pp.152-155
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• 2022

Lingual dystonia is an uncommon focal type of oromandibular dystonia that only affects the tongue. Although the use of several treatment modalities has been attempted to reduce involuntary tongue movements, such as anticonvulsants and anticholinergics, the results do not seem promising, and the efficacy of such treatments is unpredictable among patients. This case report describes botulinum toxin injection for a patient with lingual dystonia with favorable clinical results. Botulinum toxin injection to the muscles of the tongue could be an alternative treatment option for lingual dystonia.