• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.44 no.1
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• pp.29-33
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• 2018

Sinonasal mucosal melanoma (SNMM) in the maxillary sinus is a rare disease condition. Compared to oral mucosal melanoma, SNMM has a bulky, exophytic, and polypoid appearance, is weakly pigmented, and associated with unspecific symptoms. Due to these features, SNMM in the maxillary sinus has been misdiagnosed as nasal polyps and chronic sinusitis. In this case report, we described SNMM occurring in the right maxillary sinus simulated as a cystic or benign lesion. Cortical bone thinning and expansion were observed around the mass. The excised soft mass was encapsulated and weakly pigmented. The mass was clearly excised and covered with a pedicled buccal fat pad graft. Diagnosis using immunohistochemistry with S-100 and homatropine methylbromide-45 (HMB-45) is critical for proper treatment.

• Journal of Oral Medicine and Pain
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• v.48 no.3
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• pp.118-122
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• 2023

In this study, we investigate the emergence of bullous pemphigoid (BP) after the administration of the Severe Acute Respiratory Syndrome-Coronavirus Disease 2019 (SARSCOVID-19) vaccine. The study presents two cases of women, aged 47 and 53, diagnosed with BP following SARS-COVID-19 vaccination. BP is a common autoimmune blistering disorder prevalent among older populations, with an incidence rate ranging from 2 to 40 cases per million individuals. This condition arises when autoantibodies target adhesive proteins in the skin, resulting in blister formation and mucosal erosion. Drug-induced bullous pemphigoid (DIBP) shares similarities with the classic form of BP but may be influenced by medication usage. Notably, DIBP exhibits distinct characteristics, such as affecting a younger demographic and involving mucosal regions more prominently than classic BP. The growing incidence of BP is linked to factors such as an aging population and the rise of drug-induced cases. This case report provides valuable insights into comprehending DIBP, elucidating post-vaccination discomforts, particularly those related to oral lesions and the exacerbation of existing lesions. By elucidating these aspects, we aim to advance the understanding of DIBP within the medical community.

• The Journal of the Korean dental association
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• v.55 no.9
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• pp.634-639
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• 2017

Oral ulcerative and/or vesicular diseases have similar characteristics of clinical phenotypes. Detailed and careful history taking is the cornerstone of the diagnosis of oral mucosal disease. Moreover, complete screening of review of system for patient is important. Through this article, the simple ulcerative, recurrent ulcerative, acute multiple ulcer, chronic multiple ulcerative diseases will be discussed. Clinicians have to keep in mind its differential diagnosis and management.

• Journal of Oral Medicine and Pain
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• v.47 no.1
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• pp.62-66
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• 2022

Recent case studies raised the possibility that cutaneous and oral mucosal manifestations may be associated with the coronavirus disease 2019 (COVID-19) vaccination. A healthy 43-year-old male presented an acute aphthous stomatitis following Moderna COVID-19 vaccination. This rare case draws attention to a potential etiologic effect for oral mucosal manifestation from COVID-19 vaccination. Further investigation to shed light on prevalence and pathophysiologic association of this oral lesion and COVID-19 vaccination deserve attention.

• Journal of Oral Medicine and Pain
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• v.23 no.1
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• pp.1-9
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• 1998

The aim of the study was to evaluate the anesthetic Effecs of pulsed Nd:YAG laser irradiation to the oral mucosa and the teeth. Twenty subjects who didn't have a history of significant systemic or current oral disease were included in this study. All the subjects were divided randomly into the experimental group and the control group with 10 for each group. Pain thresholds were measured with Weighted Needle Pinprick Sensory Threshold Test for the mucosal surface of lower lip and with electric pulp test for the upper right central incisor respectively, before and immediately after pulsed Nd:YAG laser irradiation in the condition of 2 watt, 20pps for 2 minute at 10mm distance. The experiment was double-blinded clinical trial. The results were as follows : 1. The mean pain threshold of the mucosal surface of lower lip for Weighted Needle Pinprick Sensory Threshold Test was 2.94(1.00g for the contral group respectively, and there was no statistical difference between two groups. 2. The mean pain threshold of the mucosal surface of lower lip was significantly increased immediately after pulsed Nd:YAG laser irradiation. 3. The mean pain threshold of the upper right central incisor for eledtric pulp test was 34.50(4.97V in the experimental group and 34.00(13.08V in the control group respectively, and there was no statistical difference between two groups. 4. The mean pain threshold of the upper right central incisor was significantly increased immediately after pulsed Nd:YAG laser irradiation.

• Journal of Korean society of Dental Hygiene
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• v.16 no.3
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• pp.417-426
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• 2016

Objectives: The objective of the study was to investigate the related factors of preventive behavior experience toward dental caries and periodontal disease in Korean adolescents. Methods: The study subjects were 72,060 adolescents in 800 schools who completed 2014 Korean Youth Risk Behavior Web-based survey. Dependent variables included general characteristics of the subjects, oral health behavior, and oral disease experience. The experience rate of sealant and scaling showed the prevention behavior of dental caries and periodontal disease. Data were analyzed by IBM SPSS statistics 20.0. Results: The experience rate of sealant accounted for 26.9%. The experience of sealant was related with gender, school, maternal education level, economic status, vigorous physical activity, smoking, usual stress, fruit consumption, milk consumption, soda consumption, snack consumption, tooth brushing, oral health education experience, periodontal bleeding and pain, mucosal disorders, and bad breath. The experience rate of scaling was 22.6%. The experience of scaling was related with gender, school, city division, learning achievement, maternal education level, economic status, residential type, vigorous physical activity, usual stress, fruit consumption, milk consumption, tooth brushing, oral health education experience, periodontal bleeding and pain, mucosal disorders, and bad breath. Conclusions: To expand preventive oral health behavior in the adolescents, it is necessary to support the systematic policy making and monetary establishment in the future.

• Journal of dental hygiene science
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• v.20 no.3
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• pp.126-135
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• 2020

Background: The purpose of this study is to investigate the effects of entrance exam stress on oral health behaviors and subjective oral health status in female high school students. Methods: A self-reported questionnaire was administered to 216 female high school students in the Gwangju area. We performed an independent t-test, one-way analysis of variance (ANOVA), Pearson's correlation coefficient, and multiple regression analysis using the SPSS/WIN 21.0 program. Results: The average of the entrance exam stress was 2.73, and among the sub-areas, the tension for exam/poor stress was the highest with 3.21. As a result of analysis of general characteristics and subjective oral health status, oral mucosal disease was lower in family income level (p<0.05), bad breath was significantly higher with lower academic performance (p<0.001) and family income level (p<0.05). As a result of oral health behavior and subjective oral health status analysis, dental caries has more than 4 times of caries snacks (per week) (p<0.05), bad breath was found to be more perceived when the average number of daily brushing was 2 or less (p<0.01). Factors affecting subjective oral health status were that dental caries was a patients pressure stress (β=0.202); temporomandibular disorder (β=0.227), xerostomia (β=0.342), and oral mucosal disease (β=0.190) were insufficient spare time; bad breath was academic performance (lower) (β=0.231) and insufficient spare time (β=0.184). There was a statistically significant positive correlation between the subjective oral health status and the subarea of entrance exam stress, excluding future uncertainty stress. Conclusion: It is considered that oral health education should be conducted to prevent oral diseases for students with high parental pressure and insufficient spare time stress as well as finding practical ways to reduce entrance stress.

• Maxillofacial Plastic and Reconstructive Surgery
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• v.31 no.5
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• pp.414-418
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• 2009

Pemphigus vulgaris is a chronic autoimmune intraepithelial blistering disease with oral mucosal manifestations that very often precede the skin lesions. The vesicles or bullae are produced by an acantholytic process, detachment of differentiating keratinocytes from one another in the epithelial stratum spino sum or spinous cell layer. The pathogenesis of this disease is initially manifested by IgG(mainly) binding to desmosome(desmoglein 3 or 1) in the intercellular spaces of epithelium. This autoantibody binding caused the release of a plasminogen activator(a proteolytic enzyme) from keratinocytes. This ultimately results in cell to cell separation. The mainstay therapy of pemphigus vulgaris is systemic corticosteroids and immunosuppressive agents to eliminate the pathogenic autoantibodies from circulation. A 41-year old woman presented with a 1.5 year history of oral ulceration. There were no lesions on the skin or other mucosal sites. Histology and immunostaining were consistent with pemphigus vulgaris. Control of oral ulceration and normal oral function were achieved after systemic corticosteroids and immunosuppressive agents were instituted.

• Journal of Oral Medicine and Pain
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• v.42 no.2
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• pp.49-52
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• 2017

Leukemia is a malignant disease characterized by uncontrolled clonal proliferation of white blood cells. It is classified depending on clinical course of disease (acute or chronic) and the primary hematopoietic cell line affected (myeloid or lymphoid). Leukemia is often associated with orofacial manifestations, such as oral bleeding, petechiae, oral ulceration, gingival enlargement, mucosal pallor and mental nerve neuropathy. However, trismus has been rarely reported as a sign of leukemia. We present a case of trismus caused by acute lymphoblastic leukemia and emphasize the importance of orofacial manifestations in the early diagnosis of leukemia.

• Journal of Korean Dental Science
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• v.11 no.2
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• pp.82-85
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• 2018

Leukemia is a hematological malignant disease with various clinical symptoms. Due to the fatal nature of the disease, early detection is important. Oral manifestations include ulcers and gingival enlargement with bleeding. Moreover, myeloid sarcoma or opportunistic infections may also occur. This report introduces a 31-year-old male presenting with generalized gingival enlargement with bleeding and another 81-year-old female with neoplasm on the left retromolar area. Both were diagnosed as acute monocytic leukemia. These cases implicate that gingival enlargement or mucosal lesion in the oral cavity may represent underlying systemic diseases. Related to this, it has to be reminded that making timely diagnosis and referral according to the clinical findings is crucial.