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http://dx.doi.org/10.5125/jkaoms.2018.44.1.29

Primary sinonasal mucosal melanoma simulated as cystic lesions: a case report  

Shin, Sung-Ho (Department of Oral and Maxillofacial Surgery, College of Dentistry, Gangneung-Wonju National University)
Seok, Hyun (Department of Oral and Maxillofacial Surgery, College of Dentistry, Gangneung-Wonju National University)
Kim, Seong-Gon (Department of Oral and Maxillofacial Surgery, College of Dentistry, Gangneung-Wonju National University)
Hong, Seong-Doo (Department of Oral Pathology, School of Dentistry, Seoul National University)
Publication Information
Journal of the Korean Association of Oral and Maxillofacial Surgeons / v.44, no.1, 2018 , pp. 29-33 More about this Journal
Abstract
Sinonasal mucosal melanoma (SNMM) in the maxillary sinus is a rare disease condition. Compared to oral mucosal melanoma, SNMM has a bulky, exophytic, and polypoid appearance, is weakly pigmented, and associated with unspecific symptoms. Due to these features, SNMM in the maxillary sinus has been misdiagnosed as nasal polyps and chronic sinusitis. In this case report, we described SNMM occurring in the right maxillary sinus simulated as a cystic or benign lesion. Cortical bone thinning and expansion were observed around the mass. The excised soft mass was encapsulated and weakly pigmented. The mass was clearly excised and covered with a pedicled buccal fat pad graft. Diagnosis using immunohistochemistry with S-100 and homatropine methylbromide-45 (HMB-45) is critical for proper treatment.
Keywords
Sinonasal mucosal melanoma; Maxillary sinus; Buccal fat pad; S-100; Homatropine methylbromide-45;
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1 Choi YS, Han GS, Choi JS, Jang TY. Two cases of malignant melanoma in turbinate and maxillary sinus. Eur Arch Otorhinolaryngol 2006;263:996-1000.   DOI
2 Norhafizah M, Mustafa WM, Sabariah AR, Shiran MS, Pathmanathan R. Mucosal malignant melanoma of the maxillary sinus. Med J Malaysia 2010;65:218-20.
3 Thompson LD, Wieneke JA, Miettinen M. Sinonasal tract and nasopharyngeal melanomas: a clinicopathologic study of 115 cases with a proposed staging system. Am J Surg Pathol 2003;27:594-611.   DOI
4 Prasad ML, Busam KJ, Patel SG, Hoshaw-Woodard S, Shah JP, Huvos AG. Clinicopathologic differences in malignant melanoma arising in oral squamous and sinonasal respiratory mucosa of the upper aerodigestive tract. Arch Pathol Lab Med 2003;127:997-1002.
5 Bekci T, Aslan K, Gunbey HP, Incesu L. Primary malignant mucosal melanoma of the nasopharynx: an unusual cause of unilateral hearing loss. J Craniofac Surg 2014;25:e567-9.   DOI
6 Cheng YF, Lai CC, Ho CY, Shu CH, Lin CZ. Toward a better understanding of sinonasal mucosal melanoma: clinical review of 23 cases. J Chin Med Assoc 2007;70:24-9.   DOI
7 Clifton N, Harrison L, Bradley PJ, Jones NS. Malignant melanoma of nasal cavity and paranasal sinuses: report of 24 patients and literature review. J Laryngol Otol 2011;125:479-85.   DOI
8 Pathma L, Philip R, Harvinder S, Manjit S. Sinonasal malignant melanocytic melanoma: a rare case report. Med J Malaysia 2008;63:152-3.
9 Rinaldo A, Shaha AR, Patel SG, Ferlito A. Primary mucosal melanoma of the nasal cavity and paranasal sinuses. Acta Otolaryngol 2001;121:979-82.   DOI
10 Prasad ML. Update on pigmented lesions of the sinonasal tract. Head Neck Pathol 2007;1:50-4.   DOI
11 Roth TN, Gengler C, Huber GF, Holzmann D. Outcome of sinonasal melanoma: clinical experience and review of the literature. Head Neck 2010;32:1385-92.   DOI
12 Mochel MC, Duncan LM, Piris A, Kraft S. Primary mucosal melanoma of the sinonasal tract: a clinicopathologic and immunohistochemical study of thirty-two cases. Head Neck Pathol 2015;9:236-43.   DOI
13 Som PM, Brandwein-gensler MS, Kassel EE, Genden EM. Tumors and tumor-like conditions of the sinonasal cavities. In: Som PM, Curtin HD, eds. Head and neck imaging. St. Louis: Mosby; 2011:291-2.
14 Kung B, Deschenes GR, Keane W, Cunnane M, Jacob-Ampuero MP, Rosen M. Paranasal sinus melanoma masquerading as chronic sinusitis and nasal polyposis. Ear Nose Throat J 2007;86:561-4.
15 Lund VJ, Howard DJ, Wei WI, Cheesman AD. Craniofacial resection for tumors of the nasal cavity and paranasal sinuses: a 17-year experience. Head Neck 1998;20:97-105.   DOI
16 Giotakis EI, Kotrotsos IN. Inflammatory pseudotumour of the maxillary sinus mimicking malignancy. B-ENT 2015;11:147-50.
17 Snyder ML, Paulino AF. Melan-A as a useful diagnostic immunohistochemical stain for the diagnosis of primary sinonasal melanomas. Head Neck 2002;24:52-5.   DOI
18 Narasimhan K, Kucuk O, Lin HS, Heilbrun LK, Carron M, Venkatramanamoorthy R, et al. Sinonasal mucosal melanoma: a 13-year experience at a single institution. Skull Base 2009;19:255-62.   DOI
19 Kim CM, Park MH, Yun SW, Kim JW. Treatment of pathologic fracture following postoperative radiation therapy: clinical study. Maxillofac Plast Reconstr Surg 2015;37:31.   DOI
20 Kim MK, Han W, Kim SG. The use of the buccal fat pad flap for oral reconstruction. Maxillofac Plast Reconstr Surg 2017;39:5.   DOI