• Journal of Preventive Medicine and Public Health
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• 제9권1호
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• pp.39-47
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• 1976

The organized community is the one of the best system for the effective public health administration, and a model area was selected for the study to see what would be achieved when a certain small community is placed under the special public health control based on the family unit. The 178 families involved total of 875 populations. The rate of vaccination with B.C.G. among 191 infants and children could be increased upto 100.0% from 72.5% of the time when the basic study was performed after 8 months period of this study; 99.0% from 47.1% with D.P.T.; 96,9% from 71.7% against smallpox; 83.2% from 69.1% against poliomyelitis; but only 25,7% from 21.5% against measles. The status of family planing was 36.8% among 155 women of possible conception at the time of the basic research. And, at the end of this study, the number of women utilizing one of the methods of contraception for family planning were increased upto 52.9% among the same number. The most frequently utilized method was 34.1% of oral pills followed by 30.5% of intrauterine device; but both of which had higher rate of interruption of use because of the complications, 14.3% and 16.0% respectively. The 10 pregnant women at the time of basic research experienced normal deliveries during the period of study and they had received pre and postnatal health care through this health center. The status of oral hygiene, pulmonary tuberculosis control, and parasitological examination were also reported as well as the cases with diseases seen among the population and vaccinations performed against other infectious diseases. The stress on discussion was placed upon the effectiveness of public health administration when it is undergone on the individual family unit to achieve the best results. However, the shortness of both personnel and material resources were considered to be the one of the major difficulties retarding the generalization of the idea obtained through this study based on family unit public health administration.

• 보건행정학회지
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• 제7권2호
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• pp.19-45
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• 1997

This study was performed to evaluate the appropriateness of resource allocation based on the ranking of health center function. Through the Delphi processes, health center functions were ranked in order of importance as follows; planning and research, followed by health education, health promotion, management of chronic diseases, health screening tests, welfare activities, mental health services, medical personnel management, medical services, prevention of communicable diseases, maternal and infant health services, housekeeping, management of oral hygiene, nutrition services, surveillance for community health services, family planning, and administration of the health center. In relation to the above priorities, the allocation of manpower was not appropriate. Even though the expert groups emphasized on functions such as planning and research, health education, and health promotion, they inputted more personnel for administration of a health center, maternal and infant health services, and medical services which were evaluated with lower importance. The budget allocation showed the same trends as the above. Although the functions such as planning and research, health education, and health promotion, and management of chronic diseases were evaluated highly, the budget was allocated accordingo to the the results of the former fiscal year rather than on the importance of function. However the budget for nutrition services, surveillance for the community health services, family planning, and administration of a health center was allocated according to priority. Based upon the above findings, community health center should be given the opportunity to make their own ranking of health center function and to allocate their resources including personnel and budget in order to improve the responsibilities and roles of the community health center.

• 대한치과의료관리학회지
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• 제5권1호
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• pp.38-44
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• 2017

치위생(학)과 간 지역사회치위생학의 교육과정 개발 및 표준화를 위한 근거 마련 등의 연구 활동이 시급하다고 판단되는 바, 본 연구는 이에 대한 첫 단계로서 치위생(학)과 학생들의 지역사회구강보건 교과목의 현장 실습 만족도 조사를 실시하여 학문체계 확립과 발전을 위한 기초자료로 제공하고자 한다. 구체적인 연구 목표는 다음과 같다. 첫째, 치위생(학)과 학생들의 보건소 실습 만족도를 파악하고 둘째, 만족도에 영향을 주는 인자를 조사하여 교과목의 질 향상에 기여하고자 한다. 마지막으로, 보건소 실습 기간의 적절성을 파악하여 교육의 효율성을 높이고자 한다. 수도권에 위치한 일개 치위생학과 학부생 105명을 대상으로, 경기지역에 위치한 11개 현장실습 보건소에 대하여 실습 후 만족도를 평가하였다. 11개 보건소의 만족도 분석결과, 7점 만점에 전체 평균 5.3점으로 나타났으며 최저 3.7점, 최고 6.8점으로 나타났다. 만족도에 영향을 준 긍정적인 요인은, '편한 실습환경'이 55.2%로 가장 많이 응답하였으며, '접근성(46.7%)', '많이 배울 수 있음 (31.4%)', '기타(6.7%)' 순으로 나타났다. 이러한 만족도의 요인은 학년별로 다른 분포를 보였다. 교육의 수혜자를 대상으로 이들의 지역사회 구강보건실습 현황 및 만족도를 조사하는 것은, 사회치위생 학문의 발전과 지역사회현장실습의 표준화를 위한 초기 근거자료로서의 의의를 가질 것으로 판단된다.

• 한국환경보건학회지
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• 제23권1호
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• pp.8-13
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• 1997

Distribution and persistence of fenitrothion in rats were studied following oral administration of a single dose 300 mg/kg of body weight. Residue of the parent compound was analyzed in blood, liver, kidney, brain, lung and heart 2, 4, 6, 8 hours and 1, 2, 3, 5, 7 days after oral administration. The maximum concentration of fenitrothion appeared in the blood, kidney, heart on the 2 hour and liver, brain, lung on the 4 hour. Residues of the parent compound in kidney were much higher and persistent than other tissues and the pesticide was not detected on the 7th day. Recoveries were ranged from 83.0(lung, $1 \mu g/g$) to 97.5%(blood, $1.5 \mu g/ml$).

• Journal of Preventive Medicine and Public Health
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• 제12권1호
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• pp.43-48
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• 1979

For the purpose of further health control, D-penicillamine was orally administered to 8 persons who were employed in lead industry and suspected lead intoxication routine industrial health examination. The does of D-penicillamine was 600 mg per day and was administered orally in every other 5 days, For the laboratory analysis 24 hours urine and 10 gm of whole blood were collected every day. The results were as follows; 1. It was found that mean urinary lead excretion per day was 446.5 g/l and 394.98 g/l, respectively during the first 5-day and the second 5-day administration with D-penicillamine. 2. Mean lead excretion per day was $130.56{\pm}66.42g/l$ after first 5-day administration and $159.28{\pm}104.44g/l$ after second 5-day administration with D-penicillamine. 3. The level of urinary lead excretion after administration increased 3 to 4 times than that before administration with D-peniciilamine. 4. Blood and urinary lead level investigated after 6 months were $44.4{\pm}10.2g/100g\;and\;72.7{\pm}29.7\;g/l$ for the eight persons.

• Environmental Analysis Health and Toxicology
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• 제31권
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• pp.16.1-16.9
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• 2016

Objectives Banha-sasim-tang (BST), which consists of seven different herbs, is one of the most popular herbal formulae for treating gastrointestinal disorders in Eastern Asia. The commonly used herbal medicine is often co-administered with other therapeutic drugs, which raises the possibility of herb-drug interactions and may modify the clinical safety profile of therapeutic drugs. Methods We investigated the potential herb-drug interactions between BST extract and midazolam (MDZ) in mice. The area under the plasma concentration-time curve (AUC) of MDZ and 1'-hydroxymidazolam (1'-OH-MDZ) was evaluated for both oral and intraperitoneal administration of MDZ, following oral administration of BST (0.5 and 1 g/kg). Results It was found that the AUC of MDZ and 1'-OH-MDZ was lower in case of oral administration of MDZ. Administration of BST extract was not associated with hepatic cytochrome P450 activity. BST extract induced a strong reduction in pH and it has been reported that oral mucosal absorption of MDZ is lower at low pH. The decreased absorption rate of MDZ might be caused by the ingredients of BST and may not be related to other factors such as increased excretion of MDZ by P-glycoprotein. Conclusions The altered pharmacokinetics of midazolam caused by co-administration with BST in vivo could be attributed to a decrease in pH and subsequent reduction of MDZ absorption rate.

• Preventive Nutrition and Food Science
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• 제17권1호
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• pp.14-21
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• 2012

The purpose of this study was to investigate the anti-allergy activities of persimmon leaf extract (PLE) on a phthalic anhydride (PA)-induced allergic mouse model. A human leukemic mast cell line (HMC-1) was used to examine the inhibitory activity of PLE on the histamine release by human leukemic mast cells. PLE inhibited histamine release from HMC-1 cells in response to cross-linkage of high-affinity IgE receptor-${\alpha}$ ($Fc{\varepsilon}RI{\alpha}$). Additionally, a PA-induced allergic mouse model was used to investigate the effects of PLE in vivo. Mice were orally administrated with or without PLE of single dose (250 mg/kg/day) for 31 days. Oral intake of PLE significantly inhibited passive cutaneous reactions. Oral administration of PLE to PA-induced allergic mice also led to a striking suppression of the development of contact dermatitis, ear swelling and lymph node weight. In addition, PA-specific IL-4 production of draining lymph node cells was markedly diminished by PLE oral administration, but not IFN-${\gamma}$. Furthermore, PLE treatment suppressed PA-induced thymus and activation-regulated chemokine (CCL17) and cutaneous T cell-attracting chemokine (CCL27) expressions in ear tissues. Based on these results, we suggest that PLE may have therapeutic potential as an effective material for management of irritant contact dermatitis or related inflammatory diseases.

• 한국학교ㆍ지역보건교육학회지
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• 제21권2호
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• pp.15-26
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• 2020

Objectives: The aim of this study was to investigate the education status, knowledge, and perception of oral care among senior nursing students from Republic of Korea who completed all four curricular courses of Introduction to Nursing, Pediatric Nursing, Adult Nursing and Gerontological Nursing in order to provide basic data for effective oral care of inpatients. Methods: A questionnaire survey was conducted for 137 senior nursing students in the Seoul and Gangwon regions who were selected by convenience sampling. The questionnaire consisted of questions about the perception of oral care. A frequency analysis was conducted to analyze education status, perception, and general characteristics of participants. In addition, independent t-test and one-way analysis of variance were conducted to assess differences in the knowledge level according to the characteristics of the students. A p-value less than 0.05 was statistically significant. Results: The study results revealed that 63.5% of the respondents received education on oral care, with 67.8% of them receiving the education during their regular curriculum. Of the responders who said they received education, 41.4% said that education was not enough. Furthermore, the majority of respondents (56.9%) considered dental hygienists to be most suitable for the administration of oral care for inpatients. Conclusion: This study revealed nursing students' positive perceptions of the importance of oral care and dental hygienists'performance of oral care for inpatients. Consideration should be given to healthcare workers in various professions for improving oral health in inpatients, as well as for further study of oral care in the curriculum.

• 대한치과의사협회지
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• 제53권10호
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• pp.705-711
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• 2015

South Korea's oral health care non-governmental organizations (NGOs) have played a crucial role in South-North relations, although a formal intergovernmental relationship is difficult to establish and also easily breaks down. Humanitarian assistance by NGOs in the oral health care sector is an area that receives wide support from South Korean society for its urgency and for its appeal to humanity. This humanitarian assistance started in the late 1990's and continued to grow until the late 2000's. This assistance continued throughout the tension between the two administrations that resulted in a radical decrease in overall assistance from South Korea to North Korea. However, concerns remain about the transparency and efficiency of NGO activities. In this article, the NGOs and their major activities are delineated, and South Korean legislation is examined. A current act, the Law on the Development of South and North Korean Relations serves as a basis for governmental regulation and support of NGO's. Humanitarian assistance in the oral healthcare area is directly related to the oral health of the North Korean people, and it should not be influenced by political changes. Long-term planning and close discussions between NGOs, their North Korean counterparts, and the South Korean government are needed. NGOs need to overcome their shortcomings such as a lack of expertise and shortage of financial support. For this, NGOs must improve their administration transparency and professionalism.

• Preventive Nutrition and Food Science
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• 제18권3호
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• pp.169-174
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• 2013

The acute and subacute hypoglycemic and antihyperglycemic effects of drinkable ripe onion juice (Commercial product name is "Black Onion Extract") were investigated in normal and streptozotocin-induced diabetic rats. For tests of acute and subacute hypoglycemic effects, ripe onion juice (5 and 15 mL/kg b.w.) was administered by oral gavage to normal Sprague Dawley rats and measurements of fasting glucose levels and oral glucose tolerance tests were performed. Tolbutamide was used as a reference drug at a single oral dose of 250 mg/kg b.w. To test anti-hyperglycemic activity, the ripe onion juice was administered to streptozotocin-induced diabetic rats by oral gavage at single dose of 15 mL/kg b.w. per day for 7 consecutive days. Oral administration of the ripe onion juice at either dosed level of 5 or 15 mL/kg b.w. showed no remarkable acute hypoglycemic effect in normal rats. The two dosed levels caused a relatively small reduction, only 18% and 12% (5 and 15 mL/kg b.w., respectively) decrease in glucose levels at 2 h after glucose loading in normal rats. However, at 3 h after glucose loading, blood glucose levels in the ripe onion juice-dosed rats were decreased to the corresponding blood glucose level in tolbutamide-dosed rats. Although showing weak hypoglycemic potential compared to that of tolbutamide, oral administration of ripe onion juice (15 mL/kg b.w.) for a short period (8 days) resulted in a slight reduction in the blood glucose levels that had elevated in Streptozotocin-induced diabetic rats. In conclusion, these results suggest that the commercial product "Black Onion Extract" may possess antihyperglycemic potential in diabetes.