• 한국치위생학회지
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• 제10권2호
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• pp.283-295
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• 2010

Objectives : It surveyed the recognition level of oral health in class teachers who have influence of students' oral health knowledges and behaviors in our country, developed a program available for supplementing reinforcement in school oral health education, and planned the knowledge contents necessary for school oral health education hereafter. Methods : To arrange the basic data necessary for school oral health program, it carried out questionnaire survey by personal self-administration targeting 460 teachers for 19 elementary schools where are located in Jinhae city from May 7, 2007 to June 13. The following conclusions were obtained. Results : 1. The path of acquiring oral health knowledge was shown the high frequency with 23.9% and 23.3%, respectively, through publicity brochure and dental clinic. As for the opinion about the aim of maintaining dental hygiene, the prevention of dental caries was the highest with 53.7%. 2. The opinion about which the regular visit to the dentist is very effective for preventing dental caries accounted for 56.7%. The opinions about which the limit to sugar intake and the use of dental floss are effective for preventing dental caries accounted for 52.2% and 46.3%, respectively. 3. The opinion about which the fluoridation beverage intake and the sealant are effective for preventing dental caries accounted for 33.9% and 33.0%, respectively. 4. The opinion about which the regular toothbrushing without toothpaste has a little effect and has no effect on preventing dental caries accounted for 42.6% and 38.5%, respectively. Conclusions : The elementary-school age period, which is the most core field out of the whole oral health, is the important period that is formed the basis of lifelong oral health care. It surveyed the recognition level of oral health in class teachers who are in charge of direct health care while making continuous life with students, and developed program available for supplementing reinforcement in school oral health education. Through this, there will be necessity for cultivating ability available for properly managing oral health for the whole life by allowing elementary-school students, who will be led to future adults' oral health, to be formed the attitudes toward the rationally oral health care.

• 운동영양학회지
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• 제24권2호
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• pp.1-5
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• 2020

[Purpose] Lactate has several beneficial roles as an energy resource and in metabolism. However, studies on the effects of oral administration of lactate on fat metabolism and glycogen synthesis are limited. Therefore, the purpose of the present study was to investigate how oral administration of lactate affects fat metabolism and glycogen synthesis factors at specific times (0, 30, 60, 120 min) after intake. [Methods] Male Sprague Dawley (SD) rats (n = 24) were divided into four groups as follows: the control group (0 min) was sacrificed immediately after oral lactate administration; the test groups were administered lactate (2 g/kg) and sacrificed after 30, 60, and 120 min. Skeletal muscle and liver mRNA expression of GLUT4, FAT/CD36, PDH, CS, PC and GYS2 was assessed using reverse transcription-polymerase chain reaction. [Results] GLUT4 and FAT/CD36 expression was significantly increased in skeletal muscle 120 min after lactate administration. PDH expression in skeletal muscle was altered at 30 and 120 min after lactate consumption, but was not significantly different compared to the control. CS, PC and GYS2 expression in liver was increased 60 min after lactate administration. [Conclusion] Our results indicate that exogenous lactate administration increases GLUT4 and FAT/CD36 expression in the muscle as well as glycogen synthase factors (PC, GYS2) in the liver after 60 min. Therefore, lactate supplementation may increase fat utilization as well as induce positive effects on glycogen synthesis in athletes.

• 약학회지
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• 제55권5호
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• pp.419-425
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• 2011

To secure the good quality of pharmaceutical products, dissolution specifications for Octylonium bromide tablets and Pinaverium bromide tablets are needed to be established, which are enrolled in KPC (Korea Pharmaceutical Codex) with having no appropriate specifications. For establishing dissolution specifications, a number of experiments based on the "Guideline of Dissolution Testing for Solide Oral Dosage Forms" were performed. The results of this study will be used for revising KPC and it is expected to contribute to the incessant production of quality ensured drugs.

• 치위생과학회지
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• 제13권1호
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• pp.1-12
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• 2013

삶의 질에 대한 관심이 증가함에 따라 건강과 관련된 삶의 질 향상에 대한 관심도 증가하고 있다. 구강건강의 관점에서도 구강질환이 삶의 질을 저하시키며, 구강질환의 예방이 삶의 질을 향상시킨다. 본 연구에서는 구강보건지식과 구강보건실천 정도, 구강건강상태, 그리고 구강건강 관련 삶의 질의 관계를 알아보고자 하였다. 부산지역에 소재한 종합병원 치과, 치과병원 및 치과의원에 내원한 환자 311명을 대상으로 2010년 3월 16일부터 한달간 구조화된 자기기입식 설문지를 사용하여 대상자의 일반적 특징 및 구강보건지식, 구강보건실천, 구강건강관련 삶의 질(OHIP-14) 등에 대한 자료를 수집하였으며, 치과의사 11명이 치경과 탐침으로 사랑니를 제외한 28개의 치아를 대상으로 우식경험치아수(DMF index)를 확인하였다. 분석결과, 구강보건지식은 구강보건실천에, 구강보건실천은 우식경험치아수와 구강건강관련 삶의 질에 직접적인 영향을 미치는 것으로 나타났고, 우식경험치아수도 구강건강관련 삶의 질에 유의한 변수임을 알 수 있었다. 그러나 구강보건지식은 우식경험치아수와 구강건강관련 삶의 질에 직접적인 영향요인이 아니라, 구강보건실천의 매개를 통해 간접적으로 영향을 미치는 것으로 나타났다. 이러한 연구결과는 구강건강관련 삶의 질을 높이기 위해서는 직접적인 효과를 가지고 있는 구강보건실천 수준과 우식경험영구치아수를 적절히 관리할 수 있도록 하는 방안마련이 절실히 요구됨을 말해주고 있다. 즉 우식경험치아수는 구강보건실천에 직접적으로 영향을 받는 변수이므로 단순히 구강건강관련 지식만을 전달하기보다는 태도의 변화와 실천 행동을 유도할 수 있는 구강보건교육 프로그램을 개발함으로써 구강질환의 예방과 조기치료로 이어지도록 해야 할 것이다.

• Journal of Dental Anesthesia and Pain Medicine
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• 제20권2호
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• pp.95-99
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• 2020

Various dental procedures, such as injection administration, surgical treatment, and endodontic treatment, can cause injury to the nerves. The most commonly injured nerves are the inferior alveolar and lingual nerves. This can manifest as altered sensation to the area of innervation of the injured nerve, such as the lower lip, chin, teeth, tongue, and mucosa. Altered sensations or loss of sensation are relatively infrequent complications in daily dental practice. Here, we report an uncommon case of altered sensation in the midfacial region caused by an endodontic procedure and discuss the need to consider local dental causes in the differential diagnosis of numbness in the facial region.

• 한국동물위생학회지
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• 제28권3호
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• pp.245-251
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• 2005

The purposes of this study were to evaluate the distribution of quinolone and to investigate the effects of quinolones (enrofloxacin, ciprofloxacin) in blood(plasma) and eggs of laying hens. Animals were fed quinolones which supplemented with 20, 50, 80 mg/kg of body weight. Blood and egg samples were collected after oral administration and analyzed for quinolones (enrofloxacin, ciprofloxacin) by HPLC. In laying hens, the residue period of enrofloxacin were longer than that of ciprofloxacin and the levels of residues were elavated by drug dosage.

• 대한의생명과학회지
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• 제20권4호
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• pp.194-200
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• 2014

Ginsan, polysaccharide isolated from the root of Panax ginseng C.A. Meyer, has been shown to be a potent immunomodulator, producing several cytokines and stimulating lymphoid cells to proliferate. In this study, ginsan was orally inoculated into BALB/c mice up to 39 days and the activity of immune cells containing macrophages and T cells was analyzed. Moreover, the production of cytokines, e.g., tumor necrotic factor-${\alpha}$ (TNF-${\alpha}$), interferon-${\gamma}$ (IFN-${\gamma}$), GM-CSF and IL-12 was also analyzed. In results, the phagocytosis of macrophages was increased. About 13% cytotoxicity of NK cells was observed in 22 days and 29 days of administration. But, oral administration did not highly affect the proliferation of T cells. In cytokine analysis, 150 mg/kg and 300 mg/kg at 22 days and 29 days showed three times more increase in TNF-${\alpha}$ than the controls. IFN-${\gamma}$ showed 1.07 and 1.16 times more increase at 150 mg/kg and 300 mg/kg over 22 days, respectively more than the controls. 32 days of 150 mg/kg and 300 mg/kg induced GM-CSF of about 1.3 times more than the controls. IL-12 was not induced in samples more than the controls. Ginsan could be a potential immunostimulator. Therefore, our study suggests that it can be adapted as an immunostimulator that requires a relatively short oral administration.

• 한국치위생학회지
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• 제8권2호
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• pp.1-12
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• 2008

The purpose of this study was to examine the state of visiting oral health programs and the opinions of dental hygienists on the programs in a bid to help boost the efficiency of visiting oral health programs, To meet the goals, 341 dental hygienists in public dental clinics across the nation were asked to join a questionaire survey via e-mail in September 2007, After their views were investigated, the following findings were given: 1. In regard to the management of visiting oral health programs, 44,3 percent of the respondents carried out visiting oral health programs, and 48,3 percent of that group did that in association with visiting health care programs, There were differences among the public dental clinics in beneficiaries of visiting oral health programs, beneficiary selection criteria and the details of oral health programs, which indicated the necessity of the development of standardized models. 2. As to difficulties in fulfilling visiting health care programs, a shortage of professional knowledge was viewed as the greatest hurdle, All their scores were above average, which implied that they were not able to perform the programs successfully. 3. As for the necessity and additional expected effects of visiting oral health programs, the largest number of the dental hygienists who carried them out expected that the programs would serve to change the mind-set of locals about themselves, And the others who didn't placed the most emphasis on cooperation from other departments, and the two groups had a statistically significantly different opinion. 4. Concerning the details of visiting health care programs, the dental hygienists who performed the programs found it most necessary to provide oral health education to employees and families to be visited, The others who didn't considered it most necessary to offer oral health education to people to be visited, The necessity of denture and prosthesis was least stressed by both groups, and they took a significantly different view of treatment for dental diseases, denture and prosthesis. 5. Regarding how to bolster visiting health care programs, the dental hygienist group that carried them out put more emphasis on everything suggested in the survey, Specifically, they attached greater importance to securing sufficient budget, establishing legal foundation, setting up an administration system and determining the directions for the programs in a realistic manner, which signified the desperate need for administrative and institutional backing.

• Journal of Preventive Medicine and Public Health
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• 제9권1호
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• pp.87-94
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• 1976

In order to study the chelating action of d-penicillamine on lead and the possibility of its application to the provocation test for diagnosis of lead poisoning, urinary excretion of lead was measured from 24-hour urine samples before, during and after administration of d-penicillamine by oral route for 5 days on 18 lead workers. The results were as follows: 1. Oral d-penicillamine 600 mg/day raised the excretion of urinary lead by approximately 3 times as compared with initial urinary lead level. 2. Initial urinary lead level was the better indicator of urinary lead excretion in d-penicillamine administration than initial blood lead ${\delta}-ALA$ and hemoglobin level. 3. Oral d-penicillamine may be quite useful in provocation test for lead poisoning.

• 한국치위생학회지
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• 제15권5호
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• pp.889-898
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• 2015

Objectives: The purpose of the study is to investigate the oral health-related quality of life (OHIP-14) according to smoking in the male workers in Gunsan. Methods: A self-reported questionnaire was completed by 460 male workers in Gunsan from April 13 to 30, 2015. Among 460 workers, smokers were 205 and nonsmokers were 255. The questionnaire included three questions of general characteristics of the subjects, four questions of subjective oral health, fourteen questions of OHIP, ten questions of sobriety test (AUDIT), and eight questions of smoking (Fagerstrom Test for Nicotine Dependence, FTND). Data were analyzed by frequency analysis, t-test, ANOVA, Pearson's correlation, and multiple regression analysis using IBM SPSS(Statistical Package for the Social Science) for Windows 20.0 program. Results: In the nonsmokers, there was a negative correlation between the alcohol consumption, dental health condition, tooth pain, gum bleeding, and halitosis. The higher OHIP in the smokers had the negative correlation with nicotine dependence, alcohol consumption, tooth pain, gum bleeding, and halitosis. In order to improve OHIP, smokers are encouraged to manage gum bleeding, and non-smokers to halitosis. Conclusions: In order to improve OHIP, cessation of smoking and alcohol consumption is very important and it can lead to improve the quality of life in the workers.