• 대한치과의사협회지
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• 제54권7호
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• pp.513-520
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• 2016

In crossed occlusion, displacement of removable partial denture is likely to occur during function due to different characteristics of abutment and supporting tissue. It increases discomfort to the patient. In addition, adverse effect on the residual ridge and abutment can induce an unfavorable prognosis of the denture. In this case, a small number of implants can be placed in strategic locations. Attachment can be added for additional support and retention of removable partial denture assisted by implants. This article describes the rehabilitation of a crossed occlusion patient using implant-assisted removable partial denture with Locator$^{(R)}$ attachment. After 24 months, the patient was satisfied with the aesthetic and function of the prosthesis that is maintained stable.

• The Korean Journal of Physiology and Pharmacology
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• 제22권3호
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• pp.343-348
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• 2018

Recent human genetic studies have shown that $G{\beta}5$ is related to various clinical symptoms, such as sinus bradycardia, cognitive disability, and attention deficit hyperactivity disorder. Although the calcium signaling cascade is closely associated with a heterotrimeric G-protein, the function of $G{\beta}5$ in calcium signaling and its relevance to clinical symptoms remain unknown. In this study, we investigated the in vitro changes of store-operated calcium entry (SOCE) with exogenous expression of $G{\beta}5$. The cells expressing $G{\beta}5$ had enhanced SOCE after depletion of calcium ion inside the endoplasmic reticulum. $G{\beta}5$ also augmented Stim1- and Orai1-dependent SOCE. An ORAI1 loss-of-function mutant did not show inhibition of $G{\beta}5$-induced SOCE, and a STIM1-ERM truncation mutant showed no enhancement of SOCE. These results suggested a novel role of GNB5 and Stim1, and provided insight into the regulatory mechanism of SOCE.

• 재활치료과학
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• 제10권1호
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• pp.53-61
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• 2021

서론 : 구강운동촉진기술(OMFT)은 감각-운동, 운동 조절, 운동 학습의 이론적 배경을 바탕으로 한 치료기법으로 주요 목표는 구강 운동 기능 증진이다. OMFT에서는 구강 운동 기능의 개념적 위계 및 발달 단계는 5단계이며, 1) 감각-운동 단계, 2) 운동요소 통합 단계, 3) 구조적 움직임 단계, 4) 기능적 구강 운동 단계, 5) 통합적 구강 운동 단계로 구분하였다. 본론 : OMFT는 총 3개의 기법, 10개 범주, 50개 하위 항목으로 구성되어 있다. 자세히 살펴보면, 1) 준비 기법: 감각 인식 및 적응, 치료 적응과 목의 움직임을 통한 준비 과정으로 2범주, 12하위 항목, 2) 핵심기법: 얼굴, 입술, 볼, 잇몸, 혀, 턱 등의 구강 구조물에 치료사의 직접적인 자극을 통한 구강 운동 기술 촉진과 씹기 기능 증진을 목적으로 7개 범주, 30개 하위 항목, 3) 응용기법: 음식 섭취와 삼킬 때 도움을 줄 수 있는 치료적 접근법 1개 범주, 8개 하위 항목으로 구성된다. 결론 : 본 논문은 OMFT의 실제적 적용을 위한 구강 관련 구조물의 기능 증진을 목표로 하는 준비 기법과 핵심 기법 및 섭식을 포함한 구강 기능의 종합적인 접근을 고려한 응용 기법에 대하여 소개하는 것을 목적으로 한다.

• 구강회복응용과학지
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• 제25권4호
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• pp.329-336
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• 2009

선천적 기형이나 후천적인 외상 또는 신생물에 의해 상악골 절제술을 받은 경우, 상악에서 발생하는 구강내 결손은 흔히 비강과 상악동 및 구강이 연결된 형태로 나타난다. 이러한 상악골의 결손은 구강과 비강이 교통되어 발음, 저작, 연하 등의 기능에 이상을 초래하게 된다. 이러한 경우에도 보철치료의 기본적인 목표가 적용되며, 후천적 상악 결손부에 수복되는 폐색장치는 발음, 연하, 저작 기능을 회복할 수 있어야 하고, 적절한 심미적 만족을 제공해야 하며, 환자가 편안하게 사용할 수 있어야 한다. 상악 폐색장치의 무게를 감소시키는 것은 잔존 조직의 건강과 정상적인 기능 및 환자의 안락함을 개선시킬 수 있다. 개방형 폐색장치는 결손부의 크기에 따라 6.55~33.06% 까지 무게를 줄여줌으로써 환자에게 편안함과 편의성을 제공해 주며, 생리적 기능을 향상시켜 치아와 지지 조직에 불필요하게 가해지는 부하를 감소시켜 준다. 본 증례는 hemi-maxillectomy를 시행한 환자에서 이중온성법을 이용하여 기존의 방법보다 더 균일한 의치상 두께를 가진 폐색장치를 제작하여 환자의 기능적, 심미적인 만족을 얻었기에 이를 보고하는 바이다.

• Imaging Science in Dentistry
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• 제37권4호
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• pp.205-209
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• 2007

Purpose: To determine the physical properties of a newly developed cone beam computed tomography (CBCT). Materials and Methods: We measured and compared the imaging properties for the indirect-type flat panel detector (FPD) of a new CBCT and the single detector array (SDA) of conventional helical CT (CHCT). Results: First, the modulation transfer function (MTF) of the CBCT were superior to those of the CHCT. Second, the noise power spectrum (NPS) of the CBCT were worse than those of the CHCT. Third, detective quantum efficiency (DQE) of the indirect-type CBCT were worse than those of the CHCT at lower spatial frequencies, but were better at higher spatial frequencies. Although the comparison of contrast-to-noise ratio (CNR) was estimated in the limited range of tube current, CNR of CBCT were worse than those of CHCT. Conclusion: This study shows that the indirect-type FPD system may be useful as a CBCT detector because of high resolution.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제44권4호
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• pp.191-197
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• 2018

Objectives: The objective of the study was to evaluate the results of nasolabial/extended nasolabial flaps as a modality for treatment of oral submucous fibrosis. Materials and Methods: Eleven patients of Stage III or IVa maximum interincisal opening were selected to be operated. Nasolabial/extended nasolabial flaps were done for both the sides. All of the flaps were done in a single stage and were inferiorly based. A similar flap harvest/surgical technique was utilized for all the cases. Results: The preoperative mouth opening ranged from 5 to 16 mm, with a mean of 10.09 mm. At 6 months the mouth opening ranged from 29 to 39 mm. Some of the complications encountered were poor scar, wisdom tooth traumatising the flap, decreased mouth opening due to non compliance and too much bulk. All of theses were managed satisfactorily. Conclusion: The nasolabial flap is a very reliable flap to restore the function of oral cavity. Important adjuvant measures are habit cessation, lifestyle changes, and aggressive physiotherapy.

• 한국치위생학회지
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• 제21권4호
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• pp.383-391
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• 2021

Objectives: Based on the 7th National Health and Nutrition Examination Survey 1,135 adults aged 19 years were selected as the final study subjects to investigate the relationship between oral health and chewing difficulty in adults. Methods: Frequency analysis, chi-square test, and logistic regression analysis were performed for general characteristics, oral health behaviors, awareness symptoms, and oral health using SPSS Program 21.0. Results: Regarding factors related to chewing difficulty, the oral health was 0.44 times lower than the average level and 0.28 times lower than the good condition. In the case of oral examination, chewing difficulty was 0.85 times lower. The speaking problem was 0.11 times lower in usually than inconvenient and 0.06 times lower in not inconvenient. In the case of un-treatment, it was 0.40 times lower than that in the case of treatment. The chewing difficulty was significantly higher by 2.09 times in the case of experience of tooth pain and 1.36 times in the case of periodontal disease. Conclusions: Based on the above results, it is thought that prevention and treatment are actively needed to identify factors of oral health to improve oral health, to solve chewing difficulty and to improve chewing function.

• 한국치위생학회지
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• 제23권6호
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• pp.451-458
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• 2023

Objectives: The purpose of this study is to explore the research trends of elderly oral health through a language network analysis. Methods: A total of 354 published studies with 668 keywords were collected from the Research Information Sharing Service (RISS) between 2000 and 2022. Language network analysis was performed using Textom 6.0, Ucinet 6.774, and NetDraw 2.183. Results: The most frequent keywords were 'elderly', 'oral health', 'quality of life', and 'OHIP-14'. The result of frequency-inverse document frequent keywords showed similar results to the most frequent keywords. The N-gram of keywords shows that 'elderly', 'oral health' (18 times) and 'elderly', 'depression' (7 times). As a results of the analysis of degree centrality and between centrality, 'elderly', 'oral health', and 'quality of life' were found to be high. The CONCOR analysis identified the main clusters of 'quality of life', 'oral health behavior', 'health', and 'oral function disorder'. Conclusions: The results of the current study could be available to know research trends in elderly oral health and it is necessary to improve more comprehensive study in follow-up study.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제28권3호
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• pp.175-181
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• 2002

Intermaxillary fixation and occusal splint are routine procedure for maxillofacial fracture and orthognathic surgery. When these methods could obstruct oral airway the patients who kept intermaxillary fixation and occusal splint in their mouth, are very difficult to breath after surgery. Nasal bleeding and pharyngeal edema due to nasotracheal intubation, residual effect of muscle relaxants, and anesthetic agent could be contributing factor of airway obstruction. In this study, pulmonary function test was evaluated before and after intermaxillary fixation, and intermaxillary fixation with occusal splint in 22 volunteers. The results were as follows 1. FVC, %FVC, $FEV_1$, $FEV_1%$, PEF, $PEF_{50}$, MVV without intermaxillary fixtion were 4.45L, 88%, 4.03L, 90.9%, 10.26L/s, 5.53L/s, and 136.14L/min, and with intermaxillary fixation were 3.51L, 68.67%, 3.06L, 69.39L, 6.52L/s, 3.94L/s, and 69.39L/min. The results with intermaxillary fixation and occusal splint were 2.15L, 42.41%, 1.71L, 38.81%, 2.83L/s, 1.74L/s, and 37.14L/min. 2. Compared with before and after intermaxillary fixation, all values of pulmonary function test were decreased and after intermaxillary fixation and intermaixillary fixation with occulasal splint, the results were decreased. 3. MVV and PEF were decreased significantly with interaxillary fixtion and occusal splint, and FVC was less decreased. It meant that intermaxillary fixation and occluasal splint induced reduction of respiratory flow significantly, but less reduction of respiratory volume. 4. Intermaxillary fixation and occulsal splint induced increase of airway resistance, decrease of expiratory volume and air flow. So severe respiratory difficulty could be seen to all volunteers who kept intermaxillary fixtion and occusal splint. 5. In classification of respiratory difficulty, intermaxillary fixation with occulsal splint induced complex respiratory difficulty more than intermaxillary fixation only did. From the above results, doctors who care patients kept intermaxillary fixation and occusal splint should be aware of respiratory depression caused by these treatment.

• 약학회지
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• 제48권1호
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• pp.41-46
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• 2004

Mancozeb, a polymeric complex of zinc and manganese salts of ethylene bisthiocarbamate (EBDC), is used widely in agriculture as fungicides, insecticides, and herbicides. Mancozeb can be occupationally and environmentally exposed to human and has been reported to induce estrogenic activity, therein it is considered as an endocrine disrupter, We investigated the effects of acute exposure of Mancozeb on the immune function in mice. After single oral administration of Mancozeb to female ICR mice, the immunopathological parameters (body- and organ-weight, splenic cellularity hematological parameters), mitogen (Con A, PHA+IL-2, LPS)-induced splenocyte proliferation (SP) and splenic IgM plaque forming cell (PFC). WBC and splenic cellularity were decreased, but liver-, kidney-, and spleen-weight were increased when compared with control group. Splenic IgM PFC against SRBC was slightly lowered. Mitogen-induced proliferation of spleen cells from Mancozeb-treated mice was not signifcantly changed ex vivo, however, SP in vitro were significantly lowered in concentration dependent manner. These results indicate that Mancozeb could affect the immune function in mice.