• 한국산학기술학회논문지
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• 제18권11호
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• pp.479-485
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• 2017

본 논문은 금강 하구의 직 간접적 사용과 관련되지 않는 비사용가치를 조건부가치측정법(CVM)으로 추정하였다. 조건부가치측정법 설문에서 금강 하구의 비사용가치만을 추정하도록 유도하였고, 지불의사금액을 도출하기 위한 제시금액에 대한 양분선택적 응답 결과를 Turnbull 비모수적 추정법을 적용하여 분석하였다. 모형의 추정 결과로부터 Turnbull 하한 평균 지불의사금액을 구하면, 단일양분선택형 CV 자료에서는 5,822원(95% 신뢰구간 5,295원 ~ 6,349원)이고 이중양분선택형 CV 자료에서는 6,205원(95% 신뢰구간 5,701원 ~ 6,710원)으로 추정되었다. 따라서 본 연구에서는 두 추정치의 평균값인 6,014원(95% 신뢰구간 5,498원 ~ 6,529원)을 금강 하구의 연간 비사용가치 산정에 이용하였다. 이로부터 도출된 금강 하구의 비사용가치는 연간 연간 2,203억 원(95% 신뢰구간 2,014억 원 ~ 2,392억 원)에 이른다. 여기에는 유산가치 683억 원(95% 신뢰구간 625억 원 ~ 742억 원), 존재가치(고유가치) 580억 원(95% 신뢰구간 530억 원 ~ 630억 원) 및 선택가치 577억원(95% 신뢰구간 527억 원 ~ 626억 원) 및 대리소비가치 363억 원(95% 신뢰구간 331억 원 ~ 394억 원)이 포함되는 것으로 평가되었다.

• 한국전문물리치료학회지
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• 제24권2호
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• pp.27-36
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• 2017

Background: Research efforts to improve the pulmonary function of people with limited chest function have focused on the diaphragmatic ability to control breathing pattern. Real-time ultrasonography is appropriate to demonstrate diaphragmatic mechanism during breathing. Objective: The purpose of this study was to investigate the effects of diaphragmatic breathing training using real-time ultrasonographic imaging (RUSI) on the chest function of young females with limited chest mobility. Methods: Twenty-six subjects with limited chest mobility were randomly allocated to the experimental group (EG) and control group (CG) depending on the use of RUSI during diaphragmatic breathing training, with 13 subjects in each group. For both groups, diaphragmatic breathing training was performed for 30-min, including three 10-min sets with a 1-min rest interval. An extra option for the EG was the use of the RUSI during the training. Outcome measures comprised the diaphragmatic excursion range during quiet and deep breathing, pulmonary function (forced vital capacity; FVC, forced expiratory volume in 1-sec; FEV1, tidal volume; TV, and maximal voluntary ventilation; MVV), and chest circumferences at upper, middle, and lower levels. Results: The between-group comparison revealed that the diaphragmatic excursion range during deep breathing, FVC, and middle and lower chest circumferences were greater at post-test and that the changes between the pretest and post-test values were greater in the EG than in the CG (p<.05). In addition, the subjects in the EG showed increased post-test values for all the variables compared with the pretest values, except for TV and MVV (p<.05). In contrast, the subjects in the CG showed significant improvements for the diaphragmatic excursion range during quiet and deep breathings, FVC, FEV1, and middle and lower chest circumferences after the intervention (p<.05). Conclusion: These results indicate that using RUSI during diaphragmatic breathing training might be more beneficial for people with limited chest mobility than when diaphragmatic breathing training is used alone.

• Asian-Australasian Journal of Animal Sciences
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• 제28권10호
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• pp.1407-1418
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• 2015

A total of 32,817 test-day milk yield (TDMY) records of the first lactation of 4,056 Girolando cows daughters of 276 sires, collected from 118 herds between 2000 and 2011 were utilized to estimate the genetic parameters for TDMY via random regression models (RRM) using Legendre's polynomial functions whose orders varied from 3 to 5. In addition, nine measures of persistency in milk yield ($PS_i$) and the genetic trend of 305-day milk yield (305MY) were evaluated. The fit quality criteria used indicated RRM employing the Legendre's polynomial of orders 3 and 5 for fitting the genetic additive and permanent environment effects, respectively, as the best model. The heritability and genetic correlation for TDMY throughout the lactation, obtained with the best model, varied from 0.18 to 0.23 and from -0.03 to 1.00, respectively. The heritability and genetic correlation for persistency and 305MY varied from 0.10 to 0.33 and from -0.98 to 1.00, respectively. The use of $PS_7$ would be the most suitable option for the evaluation of Girolando cattle. The estimated breeding values for 305MY of sires and cows showed significant and positive genetic trends. Thus, the use of selection indices would be indicated in the genetic evaluation of Girolando cattle for both traits.

• 한국군사과학기술학회지
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• 제20권5호
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• pp.608-619
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• 2017

In this paper, the effects of parameters related to the residual stress induced due to laser shock peening process to determine mitigation of the initial tensile residual stresses are discussed, such as the maximum pressure, pressure pulse duration, laser spot size and number of laser shots. In order to estimate the influence of the initial tensile residual stresses, which is generated by welding in 35CD4 50HRC steel alloy, the initial condition option was employed in the finite element code. It is found that $2{\times}HEL$ maximum pressure and a certain range of the pressure pulse duration time can produce maximum mitigation effects near the surface and depth, regardless of the magnitudes of tensile residual stess. But plastically affected depth increase with increasing maximum pressure and pressure pulse duration time. For the laser spot size, maximum compressive residual stresses have almost constant values. But LSP is more effective with increasing the magnitudes of tensile residual stress. For the multiple LSP, magnitudes of compressive residual stresses and plastically affected depths are found to increase with increasing number of laser shots, but the effect is less pronounced for more laser shots. And to conclude, even though the initial tensile residual stresses such as weld residual stress field are existed, LSP is enough to make the surface and depth reinforcement effects.

• Tuberculosis and Respiratory Diseases
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• 제80권1호
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• pp.52-59
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• 2017

Background: Inhaled indacaterol (Onbrez Breezhaler), a long-acting ${\beta}_2$-agonist, is approved in over 100 countries, including South Korea, as a once-daily bronchodilator for maintenance and treatment of chronic obstructive pulmonary disease (COPD). Here, we present an interim analysis of a post-marketing surveillance study conducted to evaluate the real-world safety and effectiveness of indacaterol in the Korean population. Methods: This was an open-label, observational, prospective study in which COPD patients, who were newly prescribed with indacaterol (150 or $300{\mu}g$), were evaluated for 12 or 24 weeks. Safety was assessed based on the incidence rates of adverse events (AEs) and serious adverse events (SAEs). Effectiveness was evaluated based on physician's assessment by considering changes in symptoms and lung function, if the values of forced expiratory volume in 1 second were available. Results: Safety data were analyzed in 1,016 patients of the 1,043 enrolled COPD patients receiving indacaterol, and 784 patients were included for the effectiveness analysis. AEs were reported in 228 (22.44%) patients, while 98 (9.65%) patients reported SAEs. The COPD condition improved in 348 patients (44.4%), while the condition was maintained in 396 patients (50.5%), and only 40 patients (5.1%) exhibited worsening of ailment as compared with baseline. During the treatment period, 90 patients were hospitalized while nine patients died. All deaths were assessed to be not related to the study drug by the investigator. Conclusion: In real-life clinical practice in South Korea, indacaterol was well tolerated in COPD patients, and can be regarded as an effective option for their maintenance treatment.

• 한국축산식품학회지
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• 제38권5호
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• pp.1064-1079
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• 2018

In this study, the antimicrobial activity of a bacteriocin produced by Enterococcus faecalis KT11, isolated from traditional Kargı Tulum cheese, was determined, and bacteriocin KT11 was partially characterized. The results showed that bacteriocin KT11 was antagonistically effective against various Gram-positive and Gram-negative test bacteria, including vancomycin- and/or methicillin-resistant bacteria. The activity of bacteriocin KT11 was completely abolished after treatment with proteolytic enzymes (proteinase K, ${\alpha}$-chymotrypsin, protease and trypsin), which demonstrates the proteinaceous nature of this bacteriocin. Additionally, bacteriocin KT11 remained stable at pH values ranging from 2 to 11 and after autoclaving at $121^{\circ}C$ for 30 min. In addition, the activity of bacteriocin KT11 was stable after treatment with several surfactants (EDTA, SDS, Triton X-100, Tween 80 and urea) and organic solvents (chloroform, propanol, methanol, ethyl alcohol, acetone, hexane and ethyl ether). Cell-free supernatant of E. faecalis KT11 was subjected to ammonium sulfate precipitation and then desalted by using a 3.5-kDa cut-off dialysis membrane. The bacteriocin activity was determined to be 711 AU/mL in the dialysate. After tricine-SDS-PAGE analysis, one peptide band, which had a molecular weight of ~3.5 kDa, exhibited antimicrobial activity. Because the bacteriocin KT11, isolated from E. faecalis KT11, exhibits a broad antimicrobial spectrum, heat stability and stability over a wide pH range, this bacteriocin can be used as a potential bio-preservative in foods. Additionally, bacteriocin KT11 alone or in combination with conventional antibiotics may provide a therapeutic option for the treatment of multidrug-resistant clinical pathogens after further in vivo studies.

• Journal of the Korean Wood Science and Technology
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• 제45권1호
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• pp.72-84
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• 2017

본 연구는 국내 속리산 참나무류 도관내강면적연대기를 작성하고, 작성된 연대기가 기후프록시로써의 활용 가능성이 있는지 확인하기 위해 수행되었다. 도관내강면적연대기 작성을 위해 3가지 측정 방법이 이용되었다. 방법 1과 2는 도관내강면적이 각각 $6,000{\mu}m^2$ (MVA-60)와 $7,500{\mu}m^2$ (MVA-75) 이상인 것만 이용하여 평균값으로 연대기를 작성하는 것이고, 방법 3은 각 연륜에서 가장 큰 도관내강면적(MAX)만을 이용하여 연대기를 작성하는 것이다. MVA-60과 MVA-75는 전년도 11월부터 당년 1월까지인 겨울철 강수량과 유의성에 근접한 정의 상관을 나타냈으나, MAX는 전년도 11월에 대해서만 유의성 있는 정의 상관을 나타냈다. 본 연구결과를 근거로 국내 참나무류의 도관내강면적은 연륜기후학 분야에서 기후프록시로써 활용이 가능함이 확인되었다.

• 한국해양공학회지
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• 제21권3호
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• pp.46-51
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• 2007

A multi-purpose environmental monitoring system has been developed as a commercially available standard using the technique of hetero-core spliced fiber optic sensors, for the purposes of monitoring large-scale structures and preserving natural environments. The monitoring system has been tested and evaluated in a possible outdoor condition, in view of the full-scale operation at actual sites to be monitored. Additionally, the developed system in this work conveniently provides us with various options of sensor modules intended for monitoring such physical quantities as displacement, distortion, pressure, binary states, and liquid adhesion. Two channels of optical fiber line were monitored in each channel, three displacement sensor modules were connected in series, in order to examine the performance to a pseudo-cracking experiment in the outdoor situation and to clarify temperature influences an the system, in terms of the coupling of optical connectors and the OTDR stability. The results from the pseudo-cracking experiment agreed with the actual cracks, by means of calculation, based an the detected displacement values and their geometrical arrangement of the used sensor modules. The temperature change, ranging from 10 to $20^{\circ}C$ resulting from the 10-days free running operation, was found to influence the system stability of ${\pm}10{\mu}m$, primarily due to the coupling instability of the used optical connectors. It was found that fusion splicing, rather than the use of connectors, reduced the fluctuation dawn to ${\pm}2{\mu}m$. The specification and performance of various option modules have been demonstrated to show the capability of inspecting various physical quantities by use of the single system, which would be suitable for multi-purpose environmental monitoring.

• 대한토목학회논문집
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• 제12권4호
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• pp.157-165
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• 1992

데오돌라이트를 이용한 정밀측량시스템인 IMS가 개발되어 기계구조물의 정밀측량에 사용되고 있다. CMM(Coordinate Measuring Machine)과 같은 종래의 기계적 정밀측정장비에 비하여 측량대상물의 크기와 모양에 거의 제한이 없으며, 대상물이 설치되어 있는 현장에서 측량을 실시할 수 있다는 장점이 있으며, 또한 자료의 실시간 표현이 가능하여 대상물에 대한 관측과 위치수정을 동시에 수행할 수 있다는 장점도 가지고 있다. 본 논문에서는 IMS의 구성과 기능에 관한 고찰과 더불어, 새로이 개발된 소프트웨어의 수학적 모델이 제시되었는데, 그 모델은 해석사진측량에서의 광속조정법을 IMS의 특수성에 맞게 변형한 형태이다. 관측에서의 단계별 진행방법이 설명되었고, 그 배경 및 해석사진측량 기법과의 차이에 대하여 논의되었다. 데오돌라이트 외부표정요소와 대상물 공간좌표의 초기치를 더욱 근사(近似)하게 계산할 수 있는 새로운 IMS Calibration의 방법도 제시되었다. 대상물 관측전에 광속조정접을 적용하여 데오돌라이트 외부표정요소와 대상물 공간좌표의 초기치를 산출하도록 하였으며, 측량작업이 완료된 후 광속조정법을 이용하여 결과치를 재보정할 수 있게 하였다.

• Journal of Microbiology and Biotechnology
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• 제28권9호
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• pp.1527-1535
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• 2018

Bacterial strain BAS23 was isolated from rice field soil and identified as Bacillus amyloliquefaciens. Based on dual culture method results, the bacterium BAS23 exhibited potent in vitro inhibitory activity on mycelial growth against a broad range of dirty panicle fungal pathogens of rice (Curvularia lunata, Fusarium semitectum and Helminthosporium oryzae). Cell-free culture of BAS23 displayed a significant effect on germ tube elongation and mycelial growth. The highest dry weight reduction (%) values of C. lunata, H. oryzae and F. semitectum were 92.7%, 75.7%, and 68.9%, respectively. Analysis of electrospray ionization-mass spectrometry (ESI-MS) and $^1H$ nuclear magnetic resonance (NMR) spectroscopy revealed that the lipopeptides were iturin A with a C14 side chain (C14 iturinic acid), and a C15 side chain (C15 iturinic acid), which were produced by BAS23 when it was cultured in nutrient broth (NB) for 72 h at $30^{\circ}C$. BAS23, the efficient antagonistic bacterium, also possessed in vitro multiple traits for plant growth promotion and improved rice seedling growth. The results indicated that BAS23 represents a useful option either for biocontrol or as a plant growth-promoting agent.