• 한국항공우주학회지
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• 제48권10호
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• pp.809-819
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• 2020

본 논문에서는 전익기형 무인기의 비행 안정성 확보를 위한 날개 평면형상 및 비틀림 각을 포함하는 형상최적화 연구를 수행하였다. 전익기는 독립된 동체와 꼬리날개가 없어 공력특성과 스텔스 성능에 장점이 있는 반면, 정적 여유 및 비행 안정성 확보가 어렵다. 본 연구에서는 가로 안정성 개선을 위하여 비틀림 각과 후퇴각을 최적화 하였으며, 세로 안정성은 정적 여유와 날개 평면형상을 최적화 하여 향상시키고자 하였다. 비틀림 각의 영향은 윙렛이 장착된 형상과 비틀림 각이 있는 형상의 안정성을 비교하여 확인하였다. 최적화 문제구성에는 안정성 개선에 초점을 두어 제약조건을 수립하고 목적함수와 설계 변수를 설정하였으며, 설정된 설계 변수에 대하여 Sobol 방법을 이용해 민감도 해석을 수행하였다. 공력해석 및 안정성 해석에는 AVL이 사용되었으며, 최적화 방법으로는 SQP를 사용하였다. 최적화 결과 형상에 대한 CFD 해석 및 동안정성 시뮬레이션을 통해 비틀림 각이 윙렛을 대신하여 전익기의 스텔스 성능 향상뿐만 아니라 비행안정성 개선에도 적용될 수 있음을 검증하였다.

• Journal of Microbiology and Biotechnology
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• 제30권9호
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• pp.1412-1419
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• 2020

Human noroviruses (HuNoVs) are a leading cause of gastroenteritis outbreaks worldwide. However, the paucity of appropriate cell culture models for HuNoV replication has prevented developing effective anti-HuNoV therapies. In this study, first, the replication of the virus at various temperatures in different cells was compared, which showed that lowering the culture temperature from 37℃ significantly increased virus replication in Madin-Darby canine kidney (MDCK) cells. Second, the expression levels of autophagy-, immune-, and apoptosis-related genes at 30℃ and 37℃ were compared to explore factors affecting HuNoV replication. HuNoV cultured at 37℃ showed significantly increased autophagy-related genes (ATG5 and ATG7) and immune-related genes (IFNA, IFNB, ISG15, and NFKB) compared to mock. However, the virus cultured at 30℃ showed significantly decreased expression of autophagy-related genes (ATG5 and ATG7), but not significantly different major immune-related genes (IFNA, ISG15, and NFKB) compared to mock. Importantly, expression of the transcription factor FOXO1, which controls autophagy- and immune-related gene expression, was significantly lower at 30℃. Moreover, FOXO1 inhibition in temperature-optimized MDCK cells enhanced HuNoV replication, highlighting FOXO1 inhibition as an approach for successful virus replication. In the temperature-optimized cells, various HuNoV genotypes were successfully replicated, with GI.8 showing the highest replication levels followed by GII.1, GII.3, and GII.4. Furthermore, ultrastructural analysis of the infected cells revealed functional HuNoV replication at low temperature, with increased cellular apoptosis and decreased autophagic vacuoles. In conclusion, temperature-optimized MDCK cells can be used as a convenient culture model for HuNoV replication by inhibiting FOXO1 and providing adaptability to different genotypes.

• KSBB Journal
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• 제15권4호
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• pp.393-397
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• 2000

The cometaboic biodegradation conditionso f trichloroethylene(TCE) by Burkholderia cepacia G4 were optimized using response surface analysis. The experimental sets of phenol concentration temperature and pH were designed using central composite experimental design. The optimal conditions of phenol concentration temperature and pH were determined to be 0.91 ppm 21.5$^{\circ}C$ and 7.65 respectively by the Ridge analysis of the contour plot for TCE biodegradation rates. The TCE biodegradation rate could be enhanced up to 2.43 nmol.mg protein$.$min by response surface methodology.

• 한국콘크리트학회:학술대회논문집
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• 한국콘크리트학회 2003년도 가을 학술발표회 논문집
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• pp.132-135
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• 2003

Mechanical anchorage can substitute a standard hook. To enhance the workability and economical benefit of mechanical anchorage, the size of anchor plate should be optimized. In this paper, the pull-out behaviors such as strength, failure mode, and crack patterns of mechanically anchored reinforcement in concrete are investigated using nonlinear finite element analysis. The nonlinear finite element analysis results are consistent with the experimental results. These results show that the optimal anchor plates can be designed using the nonlinear finite element analysis.

• 한국해양공학회:학술대회논문집
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• 한국해양공학회 2004년도 학술대회지
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• pp.67-72
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• 2004

Many port states such as New Zealand, the USA, Australia and Canada have strict regulations to prevent ships which arrive in their port from discharging polluted ballast water which contain harmful aquatic organism and pathogens. They are notified that transfer of polluted ballast water can cause serious injury to public health and damage to property and environment. For this reason, they perceived that the ballast exchange in deep sea is the most effective method, together with submitting the ballast management plan which contains the effective exchange method, ballast system and safety consideration. In this study, we pursued both nautical engineering analysis and optimization of algorithm in order to generate the sequence of stability and rapidity. Heuristic Algorithm was chosen on the basis of optimality and applicability to a sequential exchange problem. We have built an optimized algorithm, for automatic exchange of ballast water, by redefining core elements of the $A^\ast$ algorithm, such as node, operator and evaluation function. Final version of the optimized algorithm has been applied to existing bulk carrier and the performance of the algorithm has been verified successfully.

• JSTS:Journal of Semiconductor Technology and Science
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• 제12권2호
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• pp.186-192
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• 2012

Half-rail stacked drivers are used to reduce power consumption of the drivers for synchronous buck converters. In this paper, the stacked driver is optimized by matching the average charging and discharging currents used by high-side and low-side drivers. By matching the two currents, the average intermediate bias voltage can remain constant without the aid of the voltage regulator as long as the voltage ripple stays within the window defined by the hysteresis of the regulator. Thus the optimized driver in this paper can minimize the power consumption in the regulator. The current matching requirement yields the value for the intermediate bias voltage, which deviates from the half-rail voltage. Furthermore the required capacitance is also reduced in this design due to decreased charging current, which results in significantly reduced die area. The detailed analysis and design of the stacked driver is verified through simulations done using 5V MOSFET parameters of a typical 0.35-${\mu}m$ CMOS process. The difference in power loss between the conventional half-rail driver and the proposed driver is less than 1%. But the conventional half-rail driver has excess charge stored in the capacitor, which will be dissipated in the regulator unless reused by an external circuit. Due to the reduction in the required capacitance, the estimated saving in chip area is approximately 18.5% compared to the half-rail driver.

• 한국컴퓨터정보학회논문지
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• 제22권9호
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• pp.57-64
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• 2017

CCSDS Standard is widely used in the international space telecommunication area. But standard recommendation of CCSDS is not restrictive, so, we can select an appropriate encryption protocol among the layer. For synchronization, encryption sync is attached in the beginning of the encrypted data. In the exceptional environmental condition, although the receiver can not decrypt the normal data, the sender have no conception of that situation. In this paper, we propose a two-stage SES alarmed link encryption synchronization method having optimized threshold value necessary to decide whether the receiver has a correct decryption or not. first, through the experiment of mutual relations between error rate and encryption synchronization detection error, we can predict worst communication environment for the selected encryption synchronization pattern. second, through the experiment for finding what number of consecutive frame synchronization error is an appropriate reference value and analysis of that experiment, we suggest an optimized threshold value for resynchronization request. lastly, through the output images we can predict the probability error that should be guaranteed by channel coder.

• 한국환경과학회지
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• 제22권12호
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• pp.1625-1631
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• 2013

In manufacturing of flatfish skin collagen peptide (FSCP) and flatfish protein hydrolysate (FPH) by reuse of dead flatfish from fish farm in Jeju island, the industrial process was optimized with the laboratory scale research and the on-field process. Segmented unit processes from raw material incoming to shipment were established to produce commercial product of FSCP and FPH. Total plate counts of FSCP were twenty five times of FPH, but food poisoning bacteria were not detected in two samples. FSCP and FPH were safe from heavy metal such as Pb(II), Cd(II) and Hg(II). The residual contents of antibiotics and disinfection matter in FSCP and FPH were not detected. The optimized process for mass production made the one-third of the running time and two times of the yield. From economic analysis, the production cost was estimated to 22,000 and 12,000 won/kg for FSCP and FPH, respectively. Therefore the product from the reuse of dead flatfish was expected to have a considerable competitive price and high added-value functional food material compared with other commercially available fish products.

• Journal of Photoscience
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• 제7권2호
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• pp.67-71
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• 2000

A quantum-chemical investigation on the conformations and electronic properties of trans(diphenyl-diheterocyclic) ethenes(t-PHEs) as building block for fully $\pi$-conjuated polymer are performed in order to display the effects of heterocyclic ring substitution. Structures for the molecules, t-PHEs were fully optimized by using semiempirical AM1, PM3 methods, and ab initio HF methods, with 6-31G basic set. The potential energy curves with respect to the change of single are obtained by using ab initio HF/6-31G basic set. The curves are not similar shapes in the molecules with respect to heterocyclic rings. It is shown that the steric repulsion interactions between phenyl ring and heterocyclic ring are subjected to different type with the respect to each heterocyclic ring. Electronic properties of the molecules were molecules were obtained by applying the optimized structures and selected geometries to the extended Huckel method. To investigate the change of HOMO-LUMO gap with respedt to the torsion angle, we select the optimized structures. By using the results, the dependency of conjugation for the energy gaps is analyzed. For t-PHE the energy gap increase up to 0.52 eV compared with its planar structure. In the cases of t-PHE and t-PHE, the energy gap increase by 1.29 and 1.15 eV, respectively, compared with its planar structure.

• 한국농공학회논문집
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• 제47권3호
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• pp.3-13
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• 2005

The conceptual rainfall-runoff models are used to predict complex hydrological effects of a basin. However, to obtain reliable results, there are some difficulties and problems in choosing optimum model, calibrating, and verifying the chosen model suitable for hydrological characteristics of the basin. In this study, Genetic Algorithm and SCE-UA method as global optimization methods were applied to compare the each optimization technique and to analyze the application for the rainfall-runoff models. Modified TANK model that is used to calculate outflow for watershed management and reservoir operation etc. was optimized as a long term rainfall-runoff model. And storage-function model that is used to predict real-time flood using historical data was optimized as a short term rainfall-runoff model. The optimized models were applied to simulate runoff on Pyeongchang-river watershed and Bocheong-stream watershed in 2001 and 2002. In the historical data study, the Genetic Algorithm and the SCE-UA method showed consistently good results considering statistical values compared with observed data.