• Journal of the Korean Society for Aeronautical & Space Sciences
• /
• v.48 no.10
• /
• pp.809-819
• /
• 2020

In this study, the twist angle and wing planform shapes were selected as design variables and optimized to secure the stability of the flying-wing type UAV. Flying-wing aircraft has no separated fuselage and tails, which has advantages in aerodynamic characteristics and stealth performance, but it is difficult to secure the flight stability. In this paper, the sweep back angle and twist angle were optimized to obtain the lateral stability, the static margin and wing planform shapes were optimized to improve the longitudinal stability of the flying-wing, then effect of the twist angle was confirmed by comparing the stability of the shape with the winglet and the shape with the twist angle. In the optimization formulation, focusing on improving stability, constraints were established, objective functions and design variables were set, then design variable sensitivity analysis was performed using the Sobol method. AVL was used for aerodynamic analysis and stability analysis, and SQP was used for optimization. The CFD analysis of the optimized shape and the simulation of the dynamic stability proved that the twist angle can be applied to the improvement of the lateral stability as well as the stealth performance in the flying-wing instead of the winglet.

• Journal of Microbiology and Biotechnology
• /
• v.30 no.9
• /
• pp.1412-1419
• /
• 2020

Human noroviruses (HuNoVs) are a leading cause of gastroenteritis outbreaks worldwide. However, the paucity of appropriate cell culture models for HuNoV replication has prevented developing effective anti-HuNoV therapies. In this study, first, the replication of the virus at various temperatures in different cells was compared, which showed that lowering the culture temperature from 37℃ significantly increased virus replication in Madin-Darby canine kidney (MDCK) cells. Second, the expression levels of autophagy-, immune-, and apoptosis-related genes at 30℃ and 37℃ were compared to explore factors affecting HuNoV replication. HuNoV cultured at 37℃ showed significantly increased autophagy-related genes (ATG5 and ATG7) and immune-related genes (IFNA, IFNB, ISG15, and NFKB) compared to mock. However, the virus cultured at 30℃ showed significantly decreased expression of autophagy-related genes (ATG5 and ATG7), but not significantly different major immune-related genes (IFNA, ISG15, and NFKB) compared to mock. Importantly, expression of the transcription factor FOXO1, which controls autophagy- and immune-related gene expression, was significantly lower at 30℃. Moreover, FOXO1 inhibition in temperature-optimized MDCK cells enhanced HuNoV replication, highlighting FOXO1 inhibition as an approach for successful virus replication. In the temperature-optimized cells, various HuNoV genotypes were successfully replicated, with GI.8 showing the highest replication levels followed by GII.1, GII.3, and GII.4. Furthermore, ultrastructural analysis of the infected cells revealed functional HuNoV replication at low temperature, with increased cellular apoptosis and decreased autophagic vacuoles. In conclusion, temperature-optimized MDCK cells can be used as a convenient culture model for HuNoV replication by inhibiting FOXO1 and providing adaptability to different genotypes.

• KSBB Journal
• /
• v.15 no.4
• /
• pp.393-397
• /
• 2000

The cometaboic biodegradation conditionso f trichloroethylene(TCE) by Burkholderia cepacia G4 were optimized using response surface analysis. The experimental sets of phenol concentration temperature and pH were designed using central composite experimental design. The optimal conditions of phenol concentration temperature and pH were determined to be 0.91 ppm 21.5$^{\circ}C$ and 7.65 respectively by the Ridge analysis of the contour plot for TCE biodegradation rates. The TCE biodegradation rate could be enhanced up to 2.43 nmol.mg protein$.$min by response surface methodology.

• Proceedings of the Korea Concrete Institute Conference
• /
• 2003.11a
• /
• pp.132-135
• /
• 2003

Mechanical anchorage can substitute a standard hook. To enhance the workability and economical benefit of mechanical anchorage, the size of anchor plate should be optimized. In this paper, the pull-out behaviors such as strength, failure mode, and crack patterns of mechanically anchored reinforcement in concrete are investigated using nonlinear finite element analysis. The nonlinear finite element analysis results are consistent with the experimental results. These results show that the optimal anchor plates can be designed using the nonlinear finite element analysis.

• Proceedings of the Korea Committee for Ocean Resources and Engineering Conference
• /
• 2004.05a
• /
• pp.67-72
• /
• 2004

Many port states such as New Zealand, the USA, Australia and Canada have strict regulations to prevent ships which arrive in their port from discharging polluted ballast water which contain harmful aquatic organism and pathogens. They are notified that transfer of polluted ballast water can cause serious injury to public health and damage to property and environment. For this reason, they perceived that the ballast exchange in deep sea is the most effective method, together with submitting the ballast management plan which contains the effective exchange method, ballast system and safety consideration. In this study, we pursued both nautical engineering analysis and optimization of algorithm in order to generate the sequence of stability and rapidity. Heuristic Algorithm was chosen on the basis of optimality and applicability to a sequential exchange problem. We have built an optimized algorithm, for automatic exchange of ballast water, by redefining core elements of the $A^\ast$ algorithm, such as node, operator and evaluation function. Final version of the optimized algorithm has been applied to existing bulk carrier and the performance of the algorithm has been verified successfully.

• JSTS:Journal of Semiconductor Technology and Science
• /
• v.12 no.2
• /
• pp.186-192
• /
• 2012

Half-rail stacked drivers are used to reduce power consumption of the drivers for synchronous buck converters. In this paper, the stacked driver is optimized by matching the average charging and discharging currents used by high-side and low-side drivers. By matching the two currents, the average intermediate bias voltage can remain constant without the aid of the voltage regulator as long as the voltage ripple stays within the window defined by the hysteresis of the regulator. Thus the optimized driver in this paper can minimize the power consumption in the regulator. The current matching requirement yields the value for the intermediate bias voltage, which deviates from the half-rail voltage. Furthermore the required capacitance is also reduced in this design due to decreased charging current, which results in significantly reduced die area. The detailed analysis and design of the stacked driver is verified through simulations done using 5V MOSFET parameters of a typical 0.35-${\mu}m$ CMOS process. The difference in power loss between the conventional half-rail driver and the proposed driver is less than 1%. But the conventional half-rail driver has excess charge stored in the capacitor, which will be dissipated in the regulator unless reused by an external circuit. Due to the reduction in the required capacitance, the estimated saving in chip area is approximately 18.5% compared to the half-rail driver.

• Journal of the Korea Society of Computer and Information
• /
• v.22 no.9
• /
• pp.57-64
• /
• 2017

CCSDS Standard is widely used in the international space telecommunication area. But standard recommendation of CCSDS is not restrictive, so, we can select an appropriate encryption protocol among the layer. For synchronization, encryption sync is attached in the beginning of the encrypted data. In the exceptional environmental condition, although the receiver can not decrypt the normal data, the sender have no conception of that situation. In this paper, we propose a two-stage SES alarmed link encryption synchronization method having optimized threshold value necessary to decide whether the receiver has a correct decryption or not. first, through the experiment of mutual relations between error rate and encryption synchronization detection error, we can predict worst communication environment for the selected encryption synchronization pattern. second, through the experiment for finding what number of consecutive frame synchronization error is an appropriate reference value and analysis of that experiment, we suggest an optimized threshold value for resynchronization request. lastly, through the output images we can predict the probability error that should be guaranteed by channel coder.

• Journal of Environmental Science International
• /
• v.22 no.12
• /
• pp.1625-1631
• /
• 2013

In manufacturing of flatfish skin collagen peptide (FSCP) and flatfish protein hydrolysate (FPH) by reuse of dead flatfish from fish farm in Jeju island, the industrial process was optimized with the laboratory scale research and the on-field process. Segmented unit processes from raw material incoming to shipment were established to produce commercial product of FSCP and FPH. Total plate counts of FSCP were twenty five times of FPH, but food poisoning bacteria were not detected in two samples. FSCP and FPH were safe from heavy metal such as Pb(II), Cd(II) and Hg(II). The residual contents of antibiotics and disinfection matter in FSCP and FPH were not detected. The optimized process for mass production made the one-third of the running time and two times of the yield. From economic analysis, the production cost was estimated to 22,000 and 12,000 won/kg for FSCP and FPH, respectively. Therefore the product from the reuse of dead flatfish was expected to have a considerable competitive price and high added-value functional food material compared with other commercially available fish products.

• Journal of Photoscience
• /
• v.7 no.2
• /
• pp.67-71
• /
• 2000

A quantum-chemical investigation on the conformations and electronic properties of trans(diphenyl-diheterocyclic) ethenes(t-PHEs) as building block for fully $\pi$-conjuated polymer are performed in order to display the effects of heterocyclic ring substitution. Structures for the molecules, t-PHEs were fully optimized by using semiempirical AM1, PM3 methods, and ab initio HF methods, with 6-31G basic set. The potential energy curves with respect to the change of single are obtained by using ab initio HF/6-31G basic set. The curves are not similar shapes in the molecules with respect to heterocyclic rings. It is shown that the steric repulsion interactions between phenyl ring and heterocyclic ring are subjected to different type with the respect to each heterocyclic ring. Electronic properties of the molecules were molecules were obtained by applying the optimized structures and selected geometries to the extended Huckel method. To investigate the change of HOMO-LUMO gap with respedt to the torsion angle, we select the optimized structures. By using the results, the dependency of conjugation for the energy gaps is analyzed. For t-PHE the energy gap increase up to 0.52 eV compared with its planar structure. In the cases of t-PHE and t-PHE, the energy gap increase by 1.29 and 1.15 eV, respectively, compared with its planar structure.

• Journal of The Korean Society of Agricultural Engineers
• /
• v.47 no.3
• /
• pp.3-13
• /
• 2005

The conceptual rainfall-runoff models are used to predict complex hydrological effects of a basin. However, to obtain reliable results, there are some difficulties and problems in choosing optimum model, calibrating, and verifying the chosen model suitable for hydrological characteristics of the basin. In this study, Genetic Algorithm and SCE-UA method as global optimization methods were applied to compare the each optimization technique and to analyze the application for the rainfall-runoff models. Modified TANK model that is used to calculate outflow for watershed management and reservoir operation etc. was optimized as a long term rainfall-runoff model. And storage-function model that is used to predict real-time flood using historical data was optimized as a short term rainfall-runoff model. The optimized models were applied to simulate runoff on Pyeongchang-river watershed and Bocheong-stream watershed in 2001 and 2002. In the historical data study, the Genetic Algorithm and the SCE-UA method showed consistently good results considering statistical values compared with observed data.