• 한국대기환경학회지
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• 제20권5호
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• pp.625-632
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• 2004

Perfluorocompounds ($PFC_s$), such as tetrafluoromethane ($CF_4$) and hexafluoroethane ($C_2F_6$), have been widely used as plasma etching and chemical vapor deposition (CVD) gases for semiconductor manufacturing processes. Since these $PFC_s$ are known to cause a greenhouse effect intensively, there has been a growing interest in reducing $PFC_s$ emissions. Among various $CF_4$ decomposing techniques, a dielectric barrier discharge (DBD) is considered as one of a promising candidate because it has been successfully used for generating ozone ($O_3$) and decomposing nitrogen oxide (NO). Firstly, optimal concentration of oxygen for $CF_4$ decomposition was found to figure out how many primary and secondary reactions are associated with DBD process. Secondary, to find effective discharge method for $CF_4$ decomposition, a streamer and a glow mode in DBD are experimentally compared, which includes (i) coaxialcylinder DBD, (ii) DBD reactor packed with glass beads. and (iii) a glow mode operation with a helium gas. The test results showed that optimal concentration of oxygen was ranged 500 ppm~1% for treating 500 ppm of $CF_4$ and helium glow discharge was the most efficient one to decompose $CF_4$.

• International Journal of Fuzzy Logic and Intelligent Systems
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• 제11권4호
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• pp.217-222
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• 2011

Genetic algorithms are one of the most important methods used to solve the Traveling Salesman Problem. Therefore, many researchers have tried to improve the Genetic Algorithm by using different methods and operations in order to find the optimal solution within reasonable time. This paper intends to find a new approach that adopts an improved genetic algorithm to solve the Traveling Salesman Problem, and compare with the well known heuristic method, namely, Kohonen Self-Organizing Map by using different data sets of symmetric TSP from TSPLIB. In order to improve the search process for the optimal solution, the proposed approach consists of three strategies: two separate tour segments sets, the improved crossover operator, and the improved mutation operator. The two separate tour segments sets are construction heuristic which produces tour of the first generation with low cost. The improved crossover operator finds the candidate fine tour segments in parents and preserves them for descendants. The mutation operator is an operator which can optimize a chromosome with mutation successfully by altering the mutation probability dynamically. The two improved operators can be used to avoid the premature convergence. Simulation experiments are executed to investigate the quality of the solution and convergence speed by using a representative set of test problems taken from TSPLIB. The results of a comparison between the new approach using the improved genetic algorithm and the Kohonen Self-Organizing Map show that the new approach yields better results for problems up to 200 cities.

• 한국멀티미디어학회논문지
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• 제6권1호
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• pp.136-147
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• 2003

주어진 문제에 대하여 최적의 성능을 가지는 신경회로망을 얻기 위해서는 학습을 통한 매개변수의 최적화 (parameter optimization)와 모델 선택을 통한 구조 최적화(structure optimization )의 통합적인 과정이 필요하다. 본 논문에서는, 각 세부 방법들의 특성을 고려하여, 공통의 특성을 갖는 방법들을 결합함으로써 효율적이면서도 일반화 성능을 높이는 총체적인 신경회로망 최적화 방법을 제안한다. 먼저 다양한 오차 함수를 사용할 수 있는 자연 기울기 강하 학습에 적응적 정규화 방법을 도입함으로써 가중치 매개변수(weight parameter)들을 최적화한다. 그리고 이렇게 최적화된 매개변수(parameter)들에 자연 프루닝(natural pruning)을 적용하여 불필요한 요소들을 제저하여 최적화 된 구조를 생성한다. 반복적인 과정에 의하여 후보 모델들을 구성하고 베이시안 정보 기준(Bayesian Information Criterion: BIC )을 이 용하여 최적의 모델을 평가하여 선택하는 방법을 제안하였다. 벤치마크 데이터에 대한 실험을 통하여 제안하는 방법의 구조 최적화 능력과 일반화 성능의 우수성을 보였다.

• 한국전기전자재료학회논문지
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• 제24권7호
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• pp.543-546
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• 2011

We studied sintering temperature to enhance the piezoelectric properties of $0.98(Na_{0.5}K_{0.5})NbO_3-0.02Li(Sb_{0.17}Ta_{0.83})O_3$+0.01wt%ZnO (hereafter NKN-LST+ZnO) lead free piezoelectric ceramics. The synthesis and sintering method were the conventional solid state reaction method and sintering was executed at $1,080\sim1,120^{\circ}C$. We found that NKN-LST+ZnO ceramics at optimal sintering temperature showed the improved piezoelectric properties at the optimal sintering temperature. The NKN-LST+ZnO ceramics show good performance with piezoelectric constant $d_{33}$= 153 pC/N sintered at $1,090^{\circ}C$. The results reveal that NKN-LST+ZnO ceramics are promising candidate materials for lead-free piezoelectric application.

• Journal of Microbiology and Biotechnology
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• 제23권9호
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• pp.1327-1338
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• 2013

The humanized anti-hepatocyte growth factor (HGF) monoclonal antibody (mAb) YYB-101 is a promising therapeutic candidate for treating various cancers. In this study, we developed a bioprocess for large-scale production of YYB-101 and evaluated its therapeutic potential for tumor treatment using a xenograft mouse model. By screening diverse chemically defined basal media formulations and by assessing the effects of various feed supplements and feeding schedules on cell growth and antibody production, we established an optimal medium and feeding method to produce 757 mg/l of YYB-101 in flask cultures, representing a 7.5-fold increase in titer compared with that obtained under non-optimized conditions. The optimal dissolved oxygen concentration for antibody production was 70% $pO_2$. A pH shift from 7.2 to 7.0, rather than controlled pH of either 7.0 or 7.2, resulted in productivity improvement in 5 L and 200 L bioreactors, yielding 737 and 830 mg/ml of YYB-101, respectively. The YYB-101 mAb highly purified by affinity chromatography using a Protein A column and two-step ion exchange chromatography effectively neutralized HGF in a cell-based assay and showed potent tumor suppression activity in a mouse xenograft model established with human glioblastoma cells.

• 산업경영시스템학회지
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• 제40권1호
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• pp.131-143
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• 2017

As the number of tourists visiting Seoul are continuously increasing, the demand of an integrative tour pass is also increasing. However, only a few tour passes are available for the tourists in Seoul. In this paper, we propose a new tour pass called "Seoul Landmark Pass" targeting foreign individual travelers and investigate the marketability of the proposed tour pass. For the configuration of the Seoul Landmark Pass we listed 17 candidate attractions charging entrance fee in Seoul, referring to e-guidebook on Visit Seoul web site. Among them we selected 6 attractions using the checklist with the attributes that foreign tourists would prefer. We also performed SWOT analyzes on existing tour passes to determine the benefits to be included in the proposed tour pass. To investigate the marketability of the proposed tour pass we have surveyed the foreign individual tourists in Seoul. Using the survey data, we have analyzed the intent of purchase by age, visiting period, visiting purpose, frequency of visit, and nationality to identify target customers. The results show that the intent of purchase is high among the Chinese tourists at the age of twenties who visited Seoul for the first time or second times. Also, the individual tourists prefer to bundle T-money card with the proposed tour pass. Finally, we have provided a brief review of the Price Sensitivity Measurement (PSM) method and applied PSM to determine the acceptable price range and the optimal price of the proposed tour pass. The optimal price of the proposed tour pass is determined at 53,000 won including T-money card.

• 한국수자원학회논문집
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• 제41권8호
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• pp.825-834
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• 2008

선진국에서의 강변여과수 개발은 150년 정도의 역사를 가지고 있다. 한국에서도 지속적으로 증가하고 있는 용수수요에 안정적으로 대처하기 위한 원수 확보방안으로 강변여과수에 대한 조사가 1990년대부터 4대강 유역을 중심으로 시작되었으며, 현재 낙동강을 중심으로 강변여과를 활용한 상수도 공급이 이루어지고 있다. 본 논문은 서울의 원수수질 안정을 위한 방안으로 강변여과 도입의 타당성에 대한 연구이다. 개발 적지의 선정을 위해 여러 가지 속성들을 계층적으로 분류하고 각 속성의 중요도를 파악함으로써 최적 대안을 선정하는 계층분석과정기법(AHP)을 적용하였다. 한강 유역의 경우 개발후보지역을 대상으로 적지분석을 실시한 결과, 수질 및 기존시설연계성 등에서 유리한 광나루지구가 최적지로 선정되었다.

• 정보처리학회논문지B
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• 제13B권6호
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• pp.585-590
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• 2006

움직임 추정은 비디오 영상 압축에서 중요한 역할을 하지만, 최적의 움직임 벡터를 찾기 위해서는 많은 탐색을 필요로 한다. 따라서 탐색시간을 줄이기 위하여 적절한 탐색 시작점 설정과 효율적인 탐색 패턴을 사용하여야 한다. 만일 움직임 추정을 수행하기 전에 현재 블록의 전체적인 움직임 정보를 예측할 수 있다면 예측된 움직임 정보를 이용하여 보다 효율적으로 움직임 추정을 수행할 수 있다. 본 논문에서는 불필요한 움직임 추정을 생략하고 현재 블록의 움직임 추정을 위한 탐색 시작점 위치와 탐색 패턴을 보다 정확히 결정하기 위해, 후보 벡터들을 이용하여 현재 블록 유형을 분류하고 현재 블록의 움직임을 예측하는 방법을 제시한다. 제안된 기법은 움직임 벡터 추정 속도 면에서 기존의 방법과 비교하여 약 1.5$\sim$7배의 속도 향상을 가져왔으며, 움직임이 많은 영상에서의 화질에 있어서 약 0.02$\sim$0.2(dB)정도 성능 향상을 보였다.

• 비파괴검사학회지
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• 제23권2호
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• pp.148-155
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• 2003

저방사화 페라이트강인 JLF는 핵융합로의 블랑켓과 같은 열교환기의 재료로써 유용한 재료이다. 이 재료의 광범위한 적용을 위해서는 JLF강과 다른 재료와의 접합기술의 개발이 중요하다. 최근 두 이종재료간의 접합에는 마찰용접이 많이 이용되고 있으며 본 연구에서도 JLF강과 STS304 간의 마찰용접에 의한 용접특성을 평가하였으며 특히 비파괴기법중의 하나인 음향방출 기법을 이용하여 두 이종재료간의 용접특성 및 최적의 용접조건을 평가하였다. 음향방출 파라미터중의 하나인 카운트와 사상수 등이 최적용접조건 및 용접품질을 평가하는데 유효한 파라미터들이었다.

• Journal of Mechanical Science and Technology
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• 제19권5호
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• pp.1072-1079
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• 2005

Conceptual design is the first step in the overall process of product design. Its intrinsic uncertainty, imprecision, and lack of information lead to the fact that current conceptual design activities in engineering have not been computerized and very few CAD systems are available to support conceptual design. In most of the current intelligent design systems, approach of principle synthesis, such as morphology matrix, bond graphic, or design catalogues, is usually adopted to deal with the concept generation, in which optional concepts are generally combined and enumerated through function analysis. However, as a large number of concepts are generated, it is difficult to evaluate and optimize these design candidates using regular algorithm. It is necessary to develop a new approach or a tool to solve the concept generation. Generally speaking, concept generation is a problem of concept synthesis. In substance, this process of developing design candidate is a combinatorial optimization process, viz., the process of concept generation can be regarded as a solution for a state-place composed of multi-concepts. In this paper, genetic algorithm is utilized as a feasible tool to solve the problem of combinatorial optimization in concept generation, in which the encoding method of morphology matrix based on function analysis is applied, and a sequence of optimal concepts are generated through the search and iterative process which is controlled by genetic operators, including selection, crossover, mutation, and reproduction in GA. Several crucial problems on GA are discussed in this paper, such as the calculation of fitness value and the criteria for heredity termination, which have a heavy effect on selection of better concepts. The feasibility and intellectualization of the proposed approach are demonstrated with an engineering case. In this work concept generation is implemented using GA, which can facilitate not only generating several better concepts, but also selecting the best concept. Thus optimal concepts can be conveniently developed and design efficiency can be greatly improved.