• Title/Summary/Keyword: Optimal Performance

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Analytical Method of Multi-Preservatives in Cosmetics using High Performance Liquid Chromatography (HPLC 를 이용한 화장품 중 살균보존제 다성분 동시분석법 연구)

  • Min-Jeong, Lee;Seong-Soo, Kim;Yun-Jeong, Lee;Byeong-Chul, Lee
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.48 no.4
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    • pp.321-330
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    • 2022
  • This study attempted to establish an optimal multi-compound simultaneous analysis method that can secure reliable results for 15 - preservatives, 2 - sun screens and 1 - antioxidants of cosmetics using HPLC-PDA. Since the potential of hydrogen (pH) in the mobile phase affects the acid dissociation constant (pKa) of the preservatives, and the peak retention time shift and area change were observed. The peak separation condition was established by adjusting the pH to 0.1% H3PO4 addition (mL) when preparing the mobile phase. As a results of method validation, the linearity correlation coefficient (R2) of above 0.999 were obtained, and accuracy 87.9 ~ 101.1%, 0.1 ~ 7.6% precision for two types of cosmetics (cream and shampoo). It was found that the limit of detection (LOD) was 0.1 ~ 0.2 mg/kg and the limit of quantitation (LOQ) was 2.0 ~ 4.0 mg/kg. In addition, it was possible to simultaneously separate p-anisic acid, a natural compound that was difficult to separate in HPLC due to the small difference from methylparaben, a synthetic preservatives. Through this study, it will be effectively used to secure quality control and safety for compound that need restrictions on use cosmetics.

Hydrogenation of Polycyclic Aromatic Hydrocarbons Over Pt/Kieselguhr Catalysts in a Trickle Bed Reactor (Trickle Bed Reactor에서 Pt/Kieselguhr 촉매를 이용한 다환방향족 탄화수소 수소화 반응)

  • Seung Kyo, Oh;Seohyeon, Oh;Gi Bo, Han;Byunghun, Jeong;Jong-Ki, Jeon
    • Clean Technology
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    • v.28 no.4
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    • pp.331-338
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    • 2022
  • The objective of this study is to prepare bead-type and pellet-type Pt (1 wt%)/Kieselguhr catalysts as hydrogenation catalysts for the polycyclic aromatic hydrocarbons (PAHs) included in pyrolysis fuel oil (PFO). The optimal reaction temperature to maximize the yield of saturated cyclic hydrocarbons during the PFO-cut hydrogenation reaction in a trickle bed reactor was determined to be 250 ℃. A hydrogen/PFO-cut flow rate ratio of 1800 was found to maximize 1-ring saturated cyclic compounds. The yield of saturated cyclic compound increased as the space velocity (LHSV) of PFO-cut decreased. The difference in hydrogenation reaction performance between the pellet catalyst and the bead catalyst was negligible. However, the catalyst impregnated by Pt after molding the Kieselguhr support (AI catalyst) showed higher hydrogenation activity than the catalyst molded after Pt impregnation on the Kieselguhr powder (BI catalyst), which was a common phenomenon in both the pellet catalysts and bead catalysts. This may be due to a higher number of active sites over the AI catalyst compared to the BI catalyst. It was confirmed that the pellet catalyst prepared by the AI method had the best reaction activity of the prepared catalysts in this study. The majority of the PFO-cut hydrogenation products were cyclic hydrocarbons ranging from C8 to C15, and C11 cyclic hydrocarbons had the highest distribution. It was confirmed that both a cracking reaction and hydrogenation occurred, which shifted the carbon number distribution towards light hydrocarbons.

Development of Multi-Reservoir System Operation Rule Curves for Hydropower Maximization in the Nam Ngum River Basin of Lao PDR (라오스 남능강 유역 다중 저수지 시스템의 최적 수력발전 운영규정 곡선 개발)

  • Lee, Hyun-Jae;Jang, Woong-Chul;Lee, Il-Ju;Lee, Jin-Hee
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.42 no.6
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    • pp.803-814
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    • 2022
  • The Lao government is continuously developing hydro-power dams in addition to the existing eight power plants in the Nam Ngum River basin and is expanding the power capacity of the existing power plants to meet the expected increase in electricity demand. Accordingly, the Lao government has requested an update on the existing reservoir operating rule curve in order to run the power plants efficiently. To this end, this study reviewed the current independent operating system as well as the joint operating system in order to maximize the annual power generation produced by a power plant by using CSUDP, general-purpose dynamic programming (DP) software. The appropriate operating regulation curve forms (URC/LRC, MRC) were extracted from the DP results, and the annual power generations were simulated by inputting them as the basic operating data of the reservoir operation set of the HEC-ResSim program. By synthesizing the amount of the annual power generation simulated, the existing operation regulation curve, the operational performance, and the opinion of the field operator, the optimal reservoir operation regulation curves that maximize the annual power generation of the target power plant were developed. Results revealed that a system operating in conjunction with the reservoir produces about 2.5 % more power generation than an independent reservoir due to the synergistic effect of the connection.

Improved Anatomical Landmark Detection Using Attention Modules and Geometric Data Augmentation in X-ray Images (어텐션 모듈과 기하학적 데이터 증강을 통한 X-ray 영상 내 해부학적 랜드마크 검출 성능 향상)

  • Lee, Hyo-Jeong;Ma, Se-Rie;Choi, Jang-Hwan
    • Journal of the Korea Computer Graphics Society
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    • v.28 no.3
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    • pp.55-65
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    • 2022
  • Recently, deep learning-based automated systems for identifying and detecting landmarks have been proposed. In order to train such a deep learning-based model without overfitting, a large amount of image and labeling data is required. Conventionally, an experienced reader manually identifies and labels landmarks in a patient's image. However, such measurement is not only expensive, but also has poor reproducibility, so the need for an automated labeling method has been raised. In addition, in the X-ray image, since various human tissues on the path through which the photons pass are displayed, it is difficult to identify the landmark compared to a general natural image or a 3D image modality image. In this study, we propose a geometric data augmentation technique that enables the generation of a large amount of labeling data in X-ray images. In addition, the optimal attention mechanism for landmark detection was presented through the implementation and application of various attention techniques to improve the detection performance of 16 major landmarks in the skull. Finally, among the major cranial landmarks, markers that ensure stable detection are derived, and these markers are expected to have high clinical application potential.

The Relationship among Localized Marketing, Brand Image, and Customer's Intention to Revisit of Korean Restaurant Franchises: Focused on Beijing, China (한식당 프랜차이즈 기업의 현지화 마케팅과 브랜드 이미지, 고객 재방문의도와의 관계: 중국 베이징 지역을 중심으로)

  • JUNG, Sung Mok;LEE, Il Han
    • The Korean Journal of Franchise Management
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    • v.13 no.2
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    • pp.1-15
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    • 2022
  • Purpose: The globalization of the Korean restaurant franchise industry differs from the business performance of enhancing the brand image and customers' intention to revisit depending on the degree of localization marketing. Therefore, it is necessary to consider the extent to which the localization marketing activities of overseas Korean restaurant franchise companies affect the customer's perception. This study aims to investigate the effects of localization marketing (Localized Menu, Localized Price, Localized Service Experience, Localized Promotion, Localized Physical Environment) of Korean restaurant franchise companies on customer revisit intention. Research design, data, and methodology: For this study, 150 questionnaires using local Korean restaurants in Beijing, China, were analyzed using SPSS Ver.21 and AMOS Ver.22. Result: It was confirmed that the localized menu, localized service experience, and localized physical environment all affect the intention to revisit customers. Based on these verification results, if overseas franchises fully recognize localization marketing, which is an important factor for local business success, and establish localization strategies, they can gain an edge in competition with local Korean restaurants or restaurant franchises founded by locals. There may be a higher probability that However, it was found that localization price and localization promotion had no mediating effect of brand image between revisit intention and revisit intention. It was found that it had no effect on the degree of inquiry and had a negative effect. Conclusions: Due to the impact of the COVID-19 pandemic, there have been many changes in the domestic and overseas food service industry over the past two years. Therefore, in future research, it is necessary to study the localization of overseas Korean restaurant franchise companies that are more multidimensionally subdivided. Various measures of customized localization marketing for optimal regional characteristics should be developed and applied to enhance customer revisiting and brand image of Korean restaurant franchise companies entering overseas. In the future, this study will be meaningful data for the establishment of localization marketing (Localized Menu, Localized Price, Localized Service Experience, Localized Promotion, Localized Physical Environment) strategies for Korean restaurant franchise companies that consider overseas expansion or have already entered.

A Comparison of Pan-sharpening Algorithms for GK-2A Satellite Imagery (천리안위성 2A호 위성영상을 위한 영상융합기법의 비교평가)

  • Lee, Soobong;Choi, Jaewan
    • Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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    • v.40 no.4
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    • pp.275-292
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    • 2022
  • In order to detect climate changes using satellite imagery, the GCOS (Global Climate Observing System) defines requirements such as spatio-temporal resolution, stability by the time change, and uncertainty. Due to limitation of GK-2A sensor performance, the level-2 products can not satisfy the requirement, especially for spatial resolution. In this paper, we found the optimal pan-sharpening algorithm for GK-2A products. The six pan-sharpening methods included in CS (Component Substitution), MRA (Multi-Resolution Analysis), VO (Variational Optimization), and DL (Deep Learning) were used. In the case of DL, the synthesis property based method was used to generate training dataset. The process of synthesis property is that pan-sharpening model is applied with Pan (Panchromatic) and MS (Multispectral) images with reduced spatial resolution, and fused image is compared with the original MS image. In the synthesis property based method, fused image with desire level for user can be produced only when the geometric characteristics between the PAN with reduced spatial resolution and MS image are similar. However, since the dissimilarity exists, RD (Random Down-sampling) was additionally used as a way to minimize it. Among the pan-sharpening methods, PSGAN was applied with RD (PSGAN_RD). The fused images are qualitatively and quantitatively validated with consistency property and the synthesis property. As validation result, the GSA algorithm performs well in the evaluation index representing spatial characteristics. In the case of spectral characteristics, the PSGAN_RD has the best accuracy with the original MS image. Therefore, in consideration of spatial and spectral characteristics of fused image, we found that PSGAN_RD is suitable for GK-2A products.

Determination of Survival of Gastric Cancer Patients With Distant Lymph Node Metastasis Using Prealbumin Level and Prothrombin Time: Contour Plots Based on Random Survival Forest Algorithm on High-Dimensionality Clinical and Laboratory Datasets

  • Zhang, Cheng;Xie, Minmin;Zhang, Yi;Zhang, Xiaopeng;Feng, Chong;Wu, Zhijun;Feng, Ying;Yang, Yahui;Xu, Hui;Ma, Tai
    • Journal of Gastric Cancer
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    • v.22 no.2
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    • pp.120-134
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    • 2022
  • Purpose: This study aimed to identify prognostic factors for patients with distant lymph node-involved gastric cancer (GC) using a machine learning algorithm, a method that offers considerable advantages and new prospects for high-dimensional biomedical data exploration. Materials and Methods: This study employed 79 features of clinical pathology, laboratory tests, and therapeutic details from 289 GC patients whose distant lymphadenopathy was presented as the first episode of recurrence or metastasis. Outcomes were measured as any-cause death events and survival months after distant lymph node metastasis. A prediction model was built based on possible outcome predictors using a random survival forest algorithm and confirmed by 5×5 nested cross-validation. The effects of single variables were interpreted using partial dependence plots. A contour plot was used to visually represent survival prediction based on 2 predictive features. Results: The median survival time of patients with GC with distant nodal metastasis was 9.2 months. The optimal model incorporated the prealbumin level and the prothrombin time (PT), and yielded a prediction error of 0.353. The inclusion of other variables resulted in poorer model performance. Patients with higher serum prealbumin levels or shorter PTs had a significantly better prognosis. The predicted one-year survival rate was stratified and illustrated as a contour plot based on the combined effect the prealbumin level and the PT. Conclusions: Machine learning is useful for identifying the important determinants of cancer survival using high-dimensional datasets. The prealbumin level and the PT on distant lymph node metastasis are the 2 most crucial factors in predicting the subsequent survival time of advanced GC.

The Experimental Study of the Ultimate Behavior of an Avalanche Tunnel Corner Rigid Joint Composited with a Centrifugal Formed Beam (초고강도 원심성형 보가 합성된 피암터널 우각부의 극한거동에 관한 실험연구)

  • Lee, Doo-Sung;Kim, Sung-Jin;Kim, Jeong-Hoi
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.26 no.6
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    • pp.128-138
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    • 2022
  • In this study, in order to apply ultra-high-strength concrete beams of 100 MPa or more manufactured by centrifugal molding as the superstructure of the avalanche tunnel, the purpose is to verify the structural safety of the corner rigid joint in which the centrifugal molded beam is integrated with the substructure, which is the negative moment area. A full-size specimen was manufactured, and loading tests and analysis studies were performed. In order to expect the same effect that the maximum moment occurs in the corner joint part of the upper slab end when the standard model of the avalanche tunnel is designed with a load combination according to the specification, a modified cantilever type structural model specimen was manufactured and the corner rigid joint was fixedly connected. A study was performed to determine the performance of the method and the optimal connection construction method. The test results demonstrated that the proposed connection system outperforms others. Despite having differences in joint connection construction type, stable flexural behavior was shown in all the tested specimens. The proposed method also outperformed the behavior of centrifugally formed beams and upper slabs. The behavior of the corner rigid joint analysis model according to the F.E. analysis showed slightly greater stiffness compared to the results of the experiment, but the overall behavior was almost similar. Therefore, there is no structural problem in the construction of the corner rigid joint between the centrifugally formed beam and the wall developed in this study.

An Extended ED-H Real-Time Scheduling Algorithm for Supporting an Intelligent PMU-Based Energy Harvesting System

  • Park, Sangsoo
    • Journal of the Korea Society of Computer and Information
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    • v.27 no.12
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    • pp.17-27
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    • 2022
  • In this paper, ED-H algorithm, an optimal real-time scheduling algorithm dealing with the characteristics of the integrated energy harvester system with a capacitor, is extended to satisfy the time constraint under the blackout state which is a deliberate power-off state by an intelligent power management unit adopted in the system. If the power supply system does not have enough energy, it temporarily shuts off the power supply to protect the circuit and capacitor and resumes the supply again when the capacitor is fully charged, which may delay the task execution during these blackout states by calculating the time according to the occurrence of the events. To mitigate the problem, even if task execution is delayed by the original ED-H algorithm, the remaining time of the subsequent time units no longer can afford to delay the execution of the task is predicted in the extended algorithm and the task is forced to be scheduled to meet the time deadline. According to the simulation results, it is confirmed that the algorithm proposed in this paper has a high scheduling performance increase of 0.4% to 7.7% depending on the characteristics of the set of tasks compared to the ED-H.

Development of Expandable Steel Pipe Piles to Improve Bearing Capacity (지지력 향상을 위한 확장형 강관말뚝에 관한 연구)

  • Kim, Uiseok;Kim, Junghoon;Kim, Jiyoon;Min, Byungchan;Choi, Hangseok
    • Journal of the Korean GEO-environmental Society
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    • v.22 no.12
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    • pp.5-13
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    • 2021
  • Expandable steel pipe piles have been developed to ensure stability and reduce construction costs during underground floor remodeling and extension work. Expandable steel pipe piles are more economical and stable than micropiles. Extensible steel pipe pile is a method of improving the performance of steel pipes by expanding steel pipes underground. In this paper, the changes in buckling strength according to the shape of steel pipes in an extended steel pipe pile were identified, a numerical analysis model was developed to determine the expended part effect of bumps due to steel pipe expansion, and the optimal steel pipe expansion was calculated through material tests. The larger the expansion diameter of the steel pipe and the greater the number of expanded part, the greater the buckling strength. Numerical results showed that the number of expanded part has a greater effect on buckling strength than the expansion rate. When the expansion rate is more than 1.2 times, it can be seen that as the number of expanded part increases, the effect of increasing buckling strength increases significantly. It was also noted that the expanded part effect of the bumps occur significantly when the extension angle is less than 45° and the expansion rate is 1.3 times higher. When the steel pipe is failure, the expanded rate is 20 to 32%, averaging 25.4%. Through the material test, it was analyzed that it is desirable to limit the maximum expansion rate for performing steel pipes to 16%.