• Title/Summary/Keyword: Optic

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An Automated Fiber-optic Biosensor Based Binding Inhibition Assay for the Detection of Listeria Monocytogenes

  • Kim, Gi-Young;Morgan, Mark;Ess, Daniel;Hahm, Byoung-Kwon;Kothapalli, Aparna;Bhunia, Arun
    • Food Science and Biotechnology
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    • v.16 no.3
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    • pp.337-342
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    • 2007
  • Conventional methods for pathogen detection and identification are labor-intensive and take days to complete. Biosensors have shown great potential for the rapid detection of foodborne pathogens. Fiber-optic biosensors have been used to rapidly detect pathogens because they can be very sensitive and are simple to operate. However, many fiber-optic biosensors rely on manual sensor handling and the sandwich assay, which require more effort and are less sensitive. To increase the simplicity of operation and detection sensitivity, a binding inhibition assay method for detecting Listeria monocytogenes in food samples was developed using an automated, fiber-optic-based immunosensor: RAPTOR (Research International, Monroe, WA, USA). For the assay, fiber-optic biosensors were developed by the immobilization of Listeria antibodies on polystyrene fiber waveguides through a biotin-avidin reaction. Developed fiber-optic biosensors were incorporated into the RAPTOR to evaluate the detection of L. monocytogenes in frankfurter samples. The binding inhibition method combined with RAPTOR was sensitive enough to detect L. monocytogenes ($5.4{\times}10^7\;CFU/mL$) in a frankfurter sample.

Metastatic Adenocarcinoma of Optic Nerve - A Case Report - (시신경에 발생한 전이성 선세포암 - 증 례 보 고 -)

  • Kim, Jin Yong;Park, Sang Keun;Kim, Han Sung;Shin, Hyung Shik;Hwang, Yong Soon;Kim, Sang Jin
    • Journal of Korean Neurosurgical Society
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    • v.29 no.8
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    • pp.1069-1073
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    • 2000
  • Although the most commonly encountered orbital tumor is metastatic tumor, adenocarcinoma of stomach metastasized to the optic nerve is rarely reported. The authors discuss a rare case of metastatic adenocarcinoma of left optic nerve with a review of literature. A 44-year-old man presented with decreased visual acuity of left eye for 3 months. Neurologic examination revealed left optic neuropathy. On MR imaging, a homogenously wellenhanced mass surrounding left optic nerve around optic canal was noticed. The X-rays and the whole body bone scan sho-wed multiple bony metastasis. Subtotal removal was performed via combined subfrontal and pterional approach and metastatic adenocarcinoma from the stomach was confirmed histologically. Postoperative course was uneventful, but there was no improvement of visual acuity.

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Fiber Optic Sensor Design for the Monitoring of Structural Sound and Vibration (구조물 음향진동 모니터링을 위한 광섬유 센서 설계)

  • Lee, Jong-Kil
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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    • 2007.05a
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    • pp.81-84
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    • 2007
  • In this paper, fiber optic sound and vibration monitoring sensor which is latticed shape structure based on Sagnac interferometer is fabricated and tested in laboratory conditions. To detect external vibrations surface mounted fibers on the latticed steel wire fence with a dimension of 170cm by 180cm is used. To detect external sound frequency the tightened fiber optic itself wire netting fence with a dimension of 50cm by 50cm is used. Experiments for the detection of the excited vibration and sound signals were performed. A small vibrator induced external vibration signal and it is applied to the latticed structure in the range of 100Hz to several kHz. External sound signal applied to the fiber optic sensor net using non-directional sound speaker. The detected optical signals were compared and analyzed to the detected both accelerometer and microphone signals in the time and frequency domain. Based on the experimental results, distributed fiber optic sensor using Sagnac interferometer detected effectively external vibration and sound signal and had a good performance. This system can be expanded to the monitoring of a significant system and to the structural health monitoring system.

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Current-induced Phase Demodulation Using a PWM Sampling for a Fiber-optic CT

  • Park, Hyoung-Jun;Lee, June-Ho;Kim, Hyun-Jin;Song, Min-Ho
    • Journal of the Optical Society of Korea
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    • v.14 no.3
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    • pp.240-244
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    • 2010
  • In this work, we used PWM sampling for demodulation of a fiber-optic interferometric current transformer. The interference signal from a fiber-optic CT is sampled with PWM triggers that produce a 90-degree phase difference between two consecutively sampled signals. The current-induced phase is extracted by applying an arctangent demodulation and a phase unwrapping algorithm to the sampled signals. From experiments using the proposed demodulation, we obtained phase measurement accuracy and a linearity error, in AC current measurements, of ~2.35 mrad and 0.18%, respectively. The accuracy of the proposed method was compared with that of a lock-in amplifier demodulation, which showed only 0.36% difference. To compare the birefringence effects of different fiber-optic sensor coils, a flint glass fiber and a standard single-mode fiber were used under the same conditions. The flint glass fiber coil with a Faraday rotator mirror showed the best performance. Because of the simple hardware structure and signal processing, the proposed demodulation would be suitable for low-cost over-current monitoring in high voltage power systems.

Design of Fiber Optic Gyroscope for Sensing High Rotation (고속회전 감지 광섬유자이로 설계)

  • Do, Jae-Chul;Chong, Kyoung-Ho;Jo, Min-Sik;Song, Ki-Won;Moon, Hong-Key
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.37 no.6
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    • pp.551-555
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    • 2009
  • We studied the design of fiber optic gyroscope that enables to sense high rotation by extending the limit of rotation sensibility of fiber optic interferometer. Based on the digital serrodyne modulation technique, the signal processing of fiber optic gyroscope was designed and the prototype fiber optic gyroscope showed the high rotation sensibility up to ${\pm}3000[deg/sec]$ and scale factor performance of about 150[ppm] by the experiments. Accordingly, we confirmed that the design of fiber optic gyroscope was valid for high rotation.

Anterior Communicating Artery Aneurysm Related to Visual Symptoms

  • Park, Jung-Hyun;Park, Sang-Keun;Kim, Tae-Hong;Shin, Jun-Jae;Shin, Hyung-Shik;Hwang, Yong-Soon
    • Journal of Korean Neurosurgical Society
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    • v.46 no.3
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    • pp.232-238
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    • 2009
  • Objective : Intracranial aneurysms are sometimes presented with visual symptoms by their rupture or direct compression of the optic nerve. It is because their prevalent sites are anatomically located close to the optic pathway. Anterior communicating artery is especially located in close proximity to optic nerve. Aneurysm arising in this area can produce visual symptoms according to their direction while the size is small. Clinical importance of visual symptoms presented by aneurysmal optic nerve compression is stressed in this study. Methods : Retrospective analysis of ruptured anterior communicating artery aneurysms compressing optic apparatus were carried out. Total 33 cases were enrolled in this study. Optic nerve compression of the aneurysms was confirmed by the surgical fields. Results : In 33 cases among 351 cases of ruptured anterior communicating artery aneurysms treated surgically, from 1991 to 2000, the dome of aneurysm was compressed in optic pathway. In some cases, aneurysm impacted into the optic nerve that deep hollowness was found when the aneurysm sac was removed during operation. Among 33 cases, 10 cases presented with preoperative visual symptoms, such as visual dimness (5), unilateral visual field defect (2) or unilateral visual loss (3), 20 cases had no visual symptoms. Visual symptoms could not be checked in 3 cases due to the poor mental state. In 6 cases among 20 cases having no visual symptoms, optic nerve was deeply compressed by the dome of aneurysm which was seen in the surgical field. Of 10 patients who had visual symptoms, 8 showed improvement in visual symptoms within 6 months after clipping of aneurysms. In 2 cases, the visual symptoms did not recover. Conclusion : Anterior communicating artery aneurysm can cause visual symptoms by compressing the optic nerve or direct rupture to the optic nerve with focal hematoma formation. We emphasize that cerebral vascular study is highly recommended to detect intracranial aneurysm before its rupture in the case of normal CT findings with visual symptoms and frequent headache.

Investigation of the Acoustic Detection in Transformer Oil Using Sagnac Fiber Optic Sensor Array (Sagnac형 광섬유 배열센서를 이용한 유증 음답 탐지 연구)

  • Lee, Jog-Kil;Lee, Seung-Hong
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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    • 2010.10a
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    • pp.533-534
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    • 2010
  • Fiber optic sensor has bee widely used in the industrial applications. For the application of acoustic detection of the high voltage electric transformer Sagnac interferometer can be used. In this paper several different materials of mandrel were used in the fiber sensor array. Based on the transformer oil fiber optic sensor is more sensitive than in the air.

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MRI의 현황과 전망

  • 전희국
    • Journal of Biomedical Engineering Research
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    • v.9 no.1
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    • pp.125-130
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    • 1988
  • In the conventional infrared imaging system, complex infrared lens systems are usually used for directing collimated narrow infrared beams into the high speed 2-dimensional optic scanner. In this paper, a simple reflective infrared optic system with a 2-dimensional optic scanner is proposed for the realization of medical infrared thermography system. It has been experimentally proven that the intfrared thermography system composed of the proposed optic system has the temperature resolution of $0.1^{\circ}C$ under the spatial resolution of lmrad, the image matrix size of $256 {\times} 240, $ and tile imaging time of 4 seconds.

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Displacement Measurement by Multiplexed Optical Loss -based Fiber Optic Sensor (다중화된 광 손실형 광섬유 센서에 의한 변위의 측정)

  • 권일범;김치엽;유정애
    • Proceedings of the Computational Structural Engineering Institute Conference
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    • 2003.10a
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    • pp.556-565
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    • 2003
  • Light losses in optical fibers are investigated by a fiber optic OTDR (Optical Time Domain Reflectometry) sensor system to develop fiber optic probes for structural displacement measurement. The displacement sensitivity was determined by the measurements of fiber-bending loss according to the gage length changes of the displacement sensor. The fiber optic displacement probe was manufactured to verify the feasibility of the structural displacement measurement.

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