• 대한소아치과학회지
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• 제28권3호
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• pp.504-511
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• 2001

예방적 레진수복은 교합면 열구전색의 개념을 확대하여 초기우식에만 국한한 와동을 형성하여 복합레진으로 충전한 후 나머지 건전한 부위의 소와열구를 치면열구전색재로 도포하는 것이다. 충전제가 첨가된 치면열구전색재로서 작은 와동의 수복도 가능하다는 새로운 방법은 소아환자의 치료시 술자와 환자 모두에게 도움을 줄 수 있을 것이다. 그러나 예방적 레진수복을 시행하여 비교한 연구가 아직까지는 부족한 실정이다. 이에 저자들은 4가지 방법의 예방적 레진수복시의 미세누출을 비교해보고자 하였으며 레진수복만을 한 경우도 함께 비교하여 보았다. 55개의 상, 하악 소구치를 준비하여 I급와동을 교합면에 형성하고 다음과 같이 수복하였다. 제1군 : 와동을 복합레진(Z-100)으로 수복 제2군 : 와동을 복합레진(Z-100)으로 수복 중합후, 비충전 전색재인 Teethmate F-1으로 소와열구도포 제3군 : 와동을 복합레진(Z-100)으로 수복 중합후, 충전 전색재인 Ultraseal XT-plus로 소와열구도포 제4군 : 와동과 소와열구를 한 번에 Ultraseal XT-plus로 수복 제5군 : 와동과 소와열구를 나누어 Ultraseal XT-plus로 수복 위와 같이 처리한 치아를 $5^{\circ}C$와 $55^{\circ}C$의 수조에 번갈아 30초씩 500회의 열순환을 실시하고 1% methylene blue용액에 24시간 담근 후 수세하고 투명레진에 매몰하였다. 매몰된 치아를 협설측으로 치아장축방향으로 평행하게 절단한 후 입체현미경으로 염색용액의 침투정도를 관찰하여 다음의 결과를 얻었다. 1. 평균 미세누출은 4군에서 가장 높았고, 3군에서 가장 낮았다. 평균 미세누출은 4>1>5>2>3군의 순으로 감소하였다. 2. 군간의 미세누출 비교에서 1군은 5군과는 통계학적으로 유의한 차이가 없었으나 2군, 3군보다 유의하게 높은 미세누출을 보였고(p<0.05), 4군보다는 유의하게 낮은 미세누출을 보였다(p<0.05). 3. 2군은 3군과는 통계학적으로 유의한 차이가 없었으나 4군, 5군보다는 유의하게 낮은 미세누출을 보였다(p<0.05). 4. 3군은 4, 5군보다 통계학적으로 유의하게 낮은 미세누출을 보였다(p<0.05). 5. 5군은 4군보다 통계학적으로 유의하게 낮은 미세누출을 보였다(p<0.05).

• 항공우주정책ㆍ법학회지
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• 제25권1호
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• pp.3-26
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• 2010

환경 문제에 있어서 세계의 리더로서 앞 서 가는 구주연합(EU)은 2012년 1월 1일부터 EU 역.내외 항공기를 막론하고 EU 회원국 영토를 출발하고 도착하는 모든 항공기 운항자에 대하여 이들 항공기 엔진에서 배출되는 이산화탄소의 배출량을 규제하는 법 Directive 2008/101/EC를 2008년 제정, 공포하였다. 이에 따라 대한항공과 아시아나를 포함하여 EU를 운항하는 많은 EU 역외 항공사들은 지난 2004-2006년 3년간 연 평균 배출량의 97%만을 2012년 배출하고 2013년부터는 95%만을 배출 허용 받으며 부족한 배출량은 배출권 거래 시장에서 구입하여 충당하여야 한다. 상기 EU 조치는 다음과 같은 법적 문제를 야기한다. 첫째, EU의 법은 범 세계적 환경조약인 교토의정서가 선진국 그룹인 기후변화협약의 Annex I 국가에게만 이산화탄소 등 지구온난화가스 배출을 감축토록 한 것에 반한다. 교토의정서 제2조 2항은 지구온난화가스 감축에 있어서 항공기 배출에 관련한 체제를 ICAO를 통하여 해결하도록 위임하였는데 지역 기구인 EU가 이를 자체 지역에만 적용하기 위하여 작성한 것도 문제이다. 둘째, 역외 항공사들이 EU로 운항하는 데에 있어서 공해와 제3국의 상공을 비행하는데 EU 역내 비행에서 이루어지지 않는 여사한 비행 중 발생하는 배출을 어떤 근거로 EU가 규제할 수 있는가이다. 셋째, EU 회원국들이 Annex I 국가로서 교토의정서 상 항공기의 국내운항 배출에 대하여서는 2012년까지 이미 배출 감축의무를 지고 있음을 감안할 때, 2012년부터 시행되는 항공기 배출 감축 조치에 non-Annex I 국가의 항공 운항자를 끌어들이면서 EU 항공사들이 적어도 2012년에는 예상치 않은 이득을 얻는다는 문제도 발생한다. 과거 유사한 EU 주도의 환경관련 국제 분쟁을 살펴본 후, 상기 EU 조치를 국제법적으로 조명하고 결론에서 EU의 조치에 대한 국내적 대처를 간략기술하였다.

• 항공우주정책ㆍ법학회지
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• 제21권2호
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• pp.157-179
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• 2006

항공보안검색 활동을 수행하기 위하여 이를 일선에서 담당하는 우리나라 항공보안요원의 법적 체계가 갖는 문제점이 무엇인지를 살펴보고 개선 안을 고찰하기 위하여 국제민간항공기구의 규정과 관행을 검토하고 일부 선진국의 항공보안체계를 고려하여 우리나라의 현행법 및 규제체제나 보안활동 수행 체계가 갖는 문제점을 파악하는데에 주력하고 이에 따른 일부 개선 안을 고려해 보았다. 즉, 현재 특수경비원 신분인 공항검색요원의 신분을 일반경비원으로 변경하여 보다 효율적인 운영을 꾀할 것을 제시하였다. 이는 우선 현행법에 의하면 항공보안업무에 대한 감독 기능은 공항운영자가 담당하도록 되어있는 한편, 실제적 보안업무인 항공여객 및 수하물 검색과 경비업무 등은 보안전문업체가 위탁 받아 수행한다. 따라서 현장에서 보안업무를 직접 수행하는 말단 근무자는 아웃소싱한 보안전문업체 소속직원이고 감독자는 공항공사 직원으로 되어 있는 것이 현실인데 그들이 특수경비원 신분으로 말미암아 경찰의 지휘를 받게 되어 지휘계통이 이원화되는 불합리한 제도가 법적 미비로 실현되고 있다. 또한 항공보안요원이라 함은 항공안전및보안에관한법률 제 2조 6호에서 본 바와 같이 그 의미를 항공기안의 질서 및 안전을 해하는 행위를 방지하는 직무를 담당하는 자로 국한하고 있다. 그러기에 공항보안요원이란 개념이 현재 법안에 규정되어 있지 않고 단지 공항운영자를 공항검색의 주체로 표현하고 있기에 제 2조 8호의 "보안검색"이란 불법방해 행위를 히는데 사용될 수 있는 무기 또는 폭발물 등 위험성이 있는 물건들을 탐지 및 수색하기 위한 행위를 말한다라는 규정에다가 이를 수행하는 자는 보안검색요원 이라하며 이는 일반경비원으로 보한다라는 개정안을 제시하는 바이다. 나아가 "사법경찰관리의직무를행할자와그직무범위에관한법률"에 공항검색요원 및 보안검색감독자를 제 7조 3항을 신설하여 추가 규정하는 방안을 제안하는 바이다. 형사소송법상 수사란 범죄혐의의 유무를 명백히 하여 공소를 제기, 유지할 것인가의 여부를 결정하기 위하여 범인을 발견, 확보하고 증거를 수집, 보전하는 수사기관의 활동을 말한다. 이는 원칙적으로 검사와 사법경찰관리가 담당한다. 그러나 특수 분야의 수사를 담당하는 사법경찰관리가 실제 운영상 필요하며 이는 형사소송법제 197조에 의하면 특수사법경찰관리라 하여 삼림, 해사, 전매, 세무, 군수사기관 기타 특별한 사항에 관하여 사법경찰관리의 직무를 행할 자와 그 직무의 범위는 법률로써 정한다는 규정에 힘입어 "사법경찰관리의직무를 행할자와그직무범위에 관한법률"이 제정되어 그 직무를 행하는 자와 직무의 범위를 법률로 정하고 있다. 이 법 제 7조 2항에 의하면 "항공기내에서 발생하는 범죄에 관하여는 기장과 승무원이 제 1항의 규정에 준하여 사법경찰관 및 사법경찰관리의 직무를 행한다"고 규정하고 있다. 이에 본인은 공항보안요원 및 검색감독자에게도 이의 권한을 주기를 제안하는 바이다. 즉 제 7조 3항을 신설하여 "공항에서 보안검색을 행하는 자 및 이의 감독자에게도 제 1항의 규정에 준하여 사법경찰관 및 사법경찰관리의 직무를 행할 권한을 부여 한다"는 규정을 추가하기를 제안한다. 는 방안을 제안하는 바이다.

• 직업교육연구
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• 제35권4호
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• pp.131-153
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• 2016

NCS의 성공은 직업능력개발훈련 기관인증평가자의 역할과 역량에 달려 있다. 이 연구는 NCS기반 직업능력개발훈련 기관인증을 위한 평가자의 역할과 역량을 도출하는 데 목적이 있다. 델파이 기법을 적용하여 평가자의 구체적 역할을 다각적으로 탐색하고, 필요한 지식과 기술, 태도 그리고 특성을 도출하여 그 타당성을 검증하고자 하였다. 이를 위해 교육훈련 전문가와 심사평가 전문가를 패널로 선정하여 3차에 걸친 델파이 연구를 진행하였다. 연구 결과, 평가자의 역할은 총 8개로 운영자, 조정 중재자, 협력자, 분석가, 검증가, 기관평가자, 기관컨설턴트, 학습자로 분류되었고, 각 역할에 따른 역량은 총 25개로 도출되었다. 지식 영역은 HRD 지식, NCS 지식, 직업능력개발훈련 지식, 훈련기관인증평가 지식의 총 4개의 역량이 포함되었다. 기술 영역은 갈등관리 능력, 대인관계 능력, 문서작성 능력, 문제해결 능력, 분석 능력, 사전준비 능력, 시간관리 능력, 의사결정 능력, 정보이해 활용 능력, 종합적사고 능력, 직업훈련기관에 대한 이해 능력, 커뮤니케이션 능력, 피드백 능력, 핵심파악 능력의 총 14개의 역량으로 구성되었다. 태도영역은 객관성 및 공정성, 서비스 마인드, 소명의식, 윤리의식, 자기개발, 책임감, 팀워크의 총 7개로 정리됐다. 이 연구의 결과로 도출된 역할과 역량은 평가자가 일정한 요건을 갖추어 공정하고 체계적으로 인증평가할 수 있도록 평가자 대상 교육프로그램을 설계하고 운영하는 데 유용할 것이다. 특히, 평가자의 경험과 역할에 따라 기초교육 및 향상 교육을 실시할 수 있도록 역량별 교육 프로그램을 모듈별로 설계하고, 지속적으로 평가자의 품질을 관리하는 데 기초자료로 활용될 것으로 기대된다.

• 한국항해항만학회지
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• 제42권6호
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• pp.507-517
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• 2018

부산항 '컨'터미널 운영문제점을 요약하면, 부산항 '컨'터미널 운영에 글로벌 선사의 미참여로 인한 환적화물 감소우려가 가장 높고 국적선사의 자가터미널 미확보로 인한 국적선사 경쟁력 약화우려, 금융투자자의 '컨'터미널 운영으로 인한 항만운영과 투자 미비로 인한 운영상 문제점 발생 그리고 다수 '컨'터미널 운영사로 인한 타부두 이송비용(ITT) 추가 발생과 비효율적인 선석활용문제가 높게 인식되고 있다. 이러한 문제점을 해소하기 위한 부산항 '컨'터미널 재구성방안으로, 환적물동량 증대에는 글로벌 선사의 참여가 가장 영향력있는 방안으로 인식되고 그 다음으로 국적선사 자가 '컨'터미널 확보로 나타나고 있다. 항만효율성 제고효과에는 '컨'터미널 통합이 가장 영향력있는 방안이고 그 다음으로 글로벌 선사 참여방안과 BPA 단일운영체제방안으로 인식하고 있다. 국적선사 서비스 경쟁력 제고효과에는 국적선사 자가 '컨'터미널 확보방안이 가장 영향력있는 방안이고 그 다음으로 역시 글로벌 선사의 터미널 운영에 참여 방안으로 나타나고 있다. 항만공공성 제고효과에는 BPA 단일운영체제방안이 가장 영향력있는 방안이고 그 다음으로 글로벌 선사 참여방안으로 인식하고 있어 부산항 경쟁력 제고와 공공성 확보를 위해서는 글로벌 선사의 항만 참여를 정책적으로 고려할 필요가 있다. 글로벌 선사의 참여방안과 터미널 통합방안 그리고 BPA 단일 운영체제방안은 부산항 강점요인간의 상호작용효과로 환적화물 증대 매우 긍정적으로 영향을 미치는 것으로 나타나고 있으며, 항만효율성 제고에는 터미널 통합방안과 강점요인 간에 상호작용효과가 긍정적인 영향을 미치고 있다. 따라서, 부산항의 강점을 최대한도로 활용하여 환적화물을 증대시키기 위해서는 '컨'터미널 운영에 글로벌 선사를 참여시키고 선석활용을 극대화하기 위해서는 터미널을 통합하며 BPA 단일운영체제방안이 터미널 관리에 효율적인 것으로 시사하고 있다.

• 지능정보연구
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• 제29권3호
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• pp.361-381
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• 2023

기업 부도 예측에 관한 연구는 재무정보를 중심으로 연구되어 왔다. 기업의 재무정보는 분기별로 갱신되기 때문에 실시간으로 기업의 폐업 가능성을 예측하는 데 있어 적시성이 부족하게 되는 문제가 발생한다. 이를 개선하고자 하는 평가 기업에서는 대상 기업의 건전성을 판단하기 위한 재무정보 외의 정보를 활용한 기업의 건전성을 판단하는 방법이 필요하다. 이를 위해 정보 기술의 발달로 기업에 대한 비재무정보 수집이 용이해지면서 기업 부도 예측에 재무정보 외의 추가적인 변수와 여러 가지 방법론을 적용하는 연구가 진행되어 왔으며, 이 중에서도 어떤 변수들이 기업의 부도를 예측하는데 영향을 주는지를 밝히는 것이 중요한 연구 과제가 되었다. 본 연구에서는 전자결제서비스를 이용하는 사업자의 폐업을 예측할 때 비재무정보를 구성하는 전자결제 정보들이 얼마나 영향을 미치는지를 살펴보았으며, 재무정보와 비재무정보 결합에 따른 폐업 예측 정확도 차이를 살펴보았다. 구체적으로, 재무정보 모형과 비재무정보 모형, 그리고 이를 결합한 모형으로 구성된 세 가지 연구 모형을 설계하였으며 Multi Layer Perceptron(MLP) 알고리즘을 포함한 여섯 가지 알고리즘으로 폐업 예측 정확도를 확인하였다. 재무정보와 비재무정보를 결합한 모형이 가장 높은 예측 정확도를 보였으며, 그 다음으로는 비재무정보 모형, 재무정보 모형의 순서로 예측 정확도가 확인되었다. 알고리즘별 폐업 예측 정확도는 여섯 가지의 알고리즘 중 XGBoost가 가장 높은 예측 정확도를 보였다. 사업자의 폐업 예측에 활용된 전체 87개의 변수를 대상으로 상대적 중요도를 살펴본 결과 폐업 예측에 중요하게 영향을 미친 변수는 상위 20개 중 70% 이상이 비재무정보인 것으로 확인되었다. 이를 통해 비재무정보의 전자결제 정보가 사업자의 폐업을 예측하는 중요한 변수임을 확인하였으며, 비재무 정보가 재무정보의 대안적 정보로서 활용할 수 있는 가능성 역시 살펴볼 수 있었다. 본 연구를 기반으로 사업자의 폐업을 예측할 수 있는 정보로서 비재무정보의 수집과 활용에 대한 중요성을 인식하고 기업의 의사결정에 활용할 수 있는 방안에 대해서도 다루었다.

• 한국지식정보기술학회논문지
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• 제13권1호
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• pp.11-23
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• 2018

본 연구에서는 스마트폰의 확산에 가장 주요한 요인이며 다양한 기능성 편의를 제공하는 앱을 구매하는 채널인 앱 마켓을 선택하는 요인을 합리적인 선택 이론 관점을 도입하여 실증적으로 밝혀내었다. 281건의 설문 결과 분석을 통해, 이익의 관점에서 사용편의성과 구조적 보장이 앱 마켓 선택에 유의미한 영향을 주는 것으로 검증 되었다. 반면, 고객신뢰, 정보 품질, 마켓 이미지는 앱마켓 선택에 유의미한 영향을 주지 못하는 것으로 파악되었다. 특히, 국내 앱마켓 플랫폼 제공자(KT, LG U+)의 경우, 해외 앱마켓 플랫폼사업자(구글)에 비해, 고객센터 운용, 피해보상 규정 등 구조적 보장 측면에서 우위에 있는 것으로 보인다. 하지만, 구글 앱 마켓의 경우는 모든 안드로이드 폰에 사전 설치되어 통신사 별로 타 앱마켓을 이용하기 위해 추가적으로 설치해야하는 불편함이 없어 국내 제공자보다 사용자 편의성에서 우위에 있다고 판단된다. 이는 국내 앱마켓 플랫폼사업자에게만 불리하게 작용하고 있어, 정책적 해결점 마련이 필요하다. 사업자비용의 관점에서는 금전적인 전환 비용과 비금전적인 전환 비용 모두 앱 마켓 선택에 유의미한 영향을 주는 것으로 나타났다. 특히, 비금전적인 전환 비용은 국내 앱마켓 플랫폼사업자에게 부정적인 영향을 주는 것으로 나타났다. 이는 국내 앱마켓의 서비스 기대 수준이 낮다고 인식되어 있고, 신규 사용자가 사용하기 위해 회원 가입 등 소요되는 시간적 비용요소가 크다고 인지되어 있다고 설명될 수 있다. 국내 앱 마켓 사업의 활성화를 위해 개선이 필요한 항목으로 보인다. 본 연구를 통해 기존 대부분의 연구들이 앱 선택 요인에만 집중되었다는 한계를 극복하고 앱 마켓 선택 요인을 밝혀내었다는데 본 연구의 의의가 있다고 볼 수 있겠다.

• 경영정보학연구
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• 제16권3호
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• pp.161-177
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• 2014

기업신용등급은 금융시장의 신뢰를 구축하고 거래를 활성화하는데 있어 매우 중요한 요소로서, 오래 전부터 학계에서는 보다 정확한 기업신용등급 예측을 가능케 하는 다양한 모형들을 연구해 왔다. 구체적으로 다중판별분석(Multiple Discriminant Analysis, MDA)이나 다항 로지스틱 회귀분석(multinomial logistic regression analysis, MLOGIT)과 같은 통계기법을 비롯해, 인공신경망(Artificial Neural Networks, ANN), 사례기반추론(Case-based Reasoning, CBR), 그리고 다분류 문제해결을 위해 확장된 다분류 Support Vector Machines(Multiclass SVM)에 이르기까지 다양한 기법들이 학자들에 의해 적용되었는데, 최근의 연구결과들에 따르면 이 중에서도 다분류 SVM이 가장 우수한 예측성과를 보이고 있는 것으로 보고되고 있다. 본 연구에서는 이러한 다분류 SVM의 성능을 한 단계 더 개선하기 위한 대안으로 유전자 알고리즘(GA, Genetic Algorithm)을 활용한 최적화 모형을 제안한다. 구체적으로 본 연구의 제안모형은 유전자 알고리즘을 활용해 다분류 SVM에 적용되어야 할 최적의 커널 함수 파라미터값들과 최적의 입력변수 집합(feature subset)을 탐색하도록 설계되었다. 실제 데이터셋을 활용해 제안모형을 적용해 본 결과, MDA나 MLOGIT, CBR, ANN과 같은 기존 인공지능/데이터마이닝 기법들은 물론 지금까지 가장 우수한 예측성과를 보이는 것으로 알려져 있던 전통적인 다분류 SVM 보다도 제안모형이 더 우수한 예측성과를 보임을 확인할 수 있었다.

• 대한의용생체공학회:의공학회지
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• 제6권2호
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• pp.1-8
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• 1985

The wall shear stress in the vicinity of end-to end anastomoses under steady flow conditions was measured using a flush-mounted hot-film anemometer(FMHFA) probe. The experimental measurements were in good agreement with numerical results except in flow with low Reynolds numbers. The wall shear stress increased proximal to the anastomosis in flow from the Penrose tubing (simulating an artery) to the PTFE: graft. In flow from the PTFE graft to the Penrose tubing, low wall shear stress was observed distal to the anastomosis. Abnormal distributions of wall shear stress in the vicinity of the anastomosis, resulting from the compliance mismatch between the graft and the host artery, might be an important factor of ANFH formation and the graft failure. The present study suggests a correlation between regions of the low wall shear stress and the development of anastomotic neointimal fibrous hyperplasia(ANPH) in end-to-end anastomoses. 30523 T00401030523 ^x Air pressure decay(APD) rate and ultrafiltration rate(UFR) tests were performed on new and saline rinsed dialyzers as well as those roused in patients several times. C-DAK 4000 (Cordis Dow) and CF IS-11 (Baxter Travenol) reused dialyzers obtained from the dialysis clinic were used in the present study. The new dialyzers exhibited a relatively flat APD, whereas saline rinsed and reused dialyzers showed considerable amount of decay. C-DAH dialyzers had a larger APD(11.70$\pm$1.32mmHg/min)compared to CF dialyzers(4.32$\pm$0.55mmHg/min)(p<0.05). However, there was no observable difference in the UFR between the two dialyzers. Neither APD nor UFR showed any significant increase with an increasing number of reuses for up to more than 20reuses. A substantial number of failures observed in APD(larger than 20mmHe/min)on the reused dialyzers(2 out of 40 CP and S out 26 C-DAK) were attributed to the Possible damage on the fibers. The CF 15-11 HFDs which failed APD test did not show changes in the UFR compared to normal dialyzers indicating that APD is a more sensitive test than UFR test to evaluate the integrity of the fibers. 30527 T00401030527 ^x For quantitative measurement of reflected light from a clinical diagnostic strip, a prototype old reflectance photometer was designed. The strip loader and cassette were made to obtain more accurate reflectance parameters. The strip was illuminated at 45˚c through optical fiber and the intensity of reflected light was determined at rectanguLat angle using a photodiode. The kubelka-munk coefficient and reflection optical density were determined ar four different wavelengths(500, 550, 570 and 610nm) for blood glucose strip. For higher concentration than 300mg/41 about glucose, a saturation state of abforbance was observed at 500, 550 and 570nm. The correlation between glucose concentration and parameters was the best at 610nm. 30535 T00401030535 ^x Radiation-induced fibrosarcoma tumors were grown on the flanks of C3H mice. The mice were divided into two groups. One group was injected with Photofrin II, intravenously (2.5mg/kg body weight). The other group received no Photofrin II. Mice from both groups were irradialed for approximately 15 minutes at 100, 300, or 500 mW/cm2 with the argon (488nm/514.5 nm), dye(628nm) and gold vapor (pulsed 628 nm) laser light. A photosensitizer behaved as an added absorber. Under our experimental conditions, the presence of Photolfrin II increased surface temperature by at least 40% and the temperature rise due to 300 mW/cm2 irradiation exceeded values for hyperthermia. Light and temperature distributions with depth were estimated by a computer model. The model demonstrated the influence of wavelength on the thermal process and proved to be a valuable tool to investigate internal temperature rise. 30536 T00401030536 ^x We investigated the structural geometry of thirty-eight Korean femurs. The purpose of this study is to identify major geometrical differences between Korean femurs 3nd others that we believe belong to Caucasians so that we would be able to get insights into the femoral component design that fits Asians including Koreans. We utilized computerized tomography (CT) images of femurs extracted from cadavers. The CT images were transformed into bitmap data by using a film scanner, and then analyzed by using a commercially available software called Image v.1.0 and a Macintosh IIci computer.The resulting data were compared with already published data. The major results show that the geometry of the Korean femurs is significantly different from that of Caucasians: (1) the anteversion angle and the canal flare index are greater by the amount of approximately 8˚ and 0.5, respectively, (2) the shape of the isthmus cross section is more round, and (3) the distance between the teaser trochanter and the proximal border of the isthmus is shelter by about 15 mm. The results suggested that the femoral component suitable for Asians should be different from the currently-used components designed and manufactured mostly by European or American companies. 30537 T00401030537 ^x It is well known that nonlinear propagation characteristics of the wave in the tissue may give very useful information for the medical diagnoisis. In this paper, a new method to detect nonlinear propagation characteristics of the internal vibration in the tissue for the low frequency mechanical vibration by using bispectral analysis is proposed. In the method, low frequency vibration of f0( = 100Hz) is applied on the surface of the object, and the waveform of the internal vibration x (t) is measured from Doppler frequency modulation of silmultaneously transmitted probing ultrasonic waves. Then, the bispectra of the signal x (t) at the frequencies (f0, f0) and (f0, 2f0) are calculated to estimate the nonlinear propagation characteristics as their magnitude ratio, w here since bispectrum is free from the gaussian additive noise we can get the value with high S/N. Basic experimental system is constructed by using 3.0 MHz probing ultrasonic waves and the several experiments are carried out for some phantoms. Results show the superiority of the proposed method to the conventional method using power spectrum and also its usefulness for the tissue characterization. 30541 T00401030541 ^x This paper describes the implementation of a computerized radial pulse diagnosis by aids of a clinical expert. On this base, we composed of the radial pulse diagnosis system in korean traditional medicine. The system composed of a radial pulse wave detection system and a radial pulse diagnosis system. With a detection system, we detected Inyoung and Cheongu radial pulse wave and processed it. Then, we have got the characteristic parameters of radial pulse wave and also quantified that according to the method of Inyoung-Cheongu Comparison Radial Pulse Diagnosis. We defined the jugement standard of radial pulse diagnosis system and then we confirmed the possibility for realization of automatic radial pulse diagnosis in korean traditional medicine. 30545 T00401030545 ^x Microspheres are expected to be applied to biomedical areas such as solid-phase immunoassays, drug delivery systems, immunomagnetic cell separation. To synthesize microspheres for biomedical application, "two stage shot growth method" was developed. The uniformity ratio of synthesized microspheres was always smaller than 1.05. And the surface charge density (or the number of ionizable functional groups) of the microspheres synthesized by "two stage shot growth method" was 6~13 times higher than that of the microspheres synthesized by conventional seeded batch copolymerization. As a previous step for biomedical application, adsorption experiments of bovine albumin on microspheres were carried out under various conditions. The maximum adsorbed amount was obtained in the neighborhood of pH 4.5. Isoelectric point of bovine albumin is pH 5.0, so experimental result shows that it shifted to acid area. The adsorption isotherm was obtained, the plateau region was always reached at 2.Og/L (bulk concentration of bovine albumin).The effect of the kind and the amount of surface functional group was also examined. 30575 T00401030575 ^x A medical image workstation was developed using multimedia technique. The system based on PC-486DX was designed to acquire medical images produced by medical imaging instruments and related audio information, that is, doctors' reporting results. Input information was processed and analyzed, then the results were presented in the form of graph and animation. All the informations of the system were hierarchically related with the image as the apex. Processing and analysis algorithms were implemented so that the diagnostic accuracy could be improved. The diagnosed information can be transferred for patient diagnosis through LAN(local area network). 30592 T00401030592 ^x In the conventional infrared imaging system, complex infrared lens systems are usually used for directing collimated narrow infrared beams into the high speed 2-dimensional optic scanner. In this paper, a simple reflective infrared optic system with a 2-dimensional optic scanner is proposed for the realization of medical infrared thermography system. It has been experimentally proven that the intfrared thermography system composed of the proposed optic system has the temperature resolution of 0.1˚c under the spatial resolution of lmrad, the image matrix size of 256 X 240, and tile imaging time of 4 seconds. 30593 T00401030593 ^x In this paper, MIIS (Medical Image Information System) has been designed and implemented using INGRES RDBMS, which is based on a client/server architecture. The implemented system allows users to register and retrieve patient information, medical images and diagnostic reports. It also provides the function to display these information on workstation windows simultaneously by using the designed menu-driven graphic user interface. The medical image compression/decompression techniques are implemented and integrated into the medical image database system for the efficient data storage and the fast access through the network. 30594 T00401030594 ^x In this paper, computerized BEAM was implemented for the space domain analysis of EEG. Trans-formation from temporal summation to two-dimensional mappings is formed by 4 nearest point inter-polaton method. Methods of representation of BEAM are two. One is dot density method which classify brain electrical potential 9 levels by dot density of gray levels and the other is colour method which classify brain electrical 12 levels by red-green colours. In this BEAM, instantaneous change and average energy distribution over any arbitrary time interval of brain electrical activity could be observed and analyzed easily. In the frequency domain, the distribution of energy spectrum of a special band can easily be distinguished normality and abnormality. 30608 T00401030608 ^x Laboratory information system (LIS) is a key tool to manage laboratory data in clinical pathology. Our department has developed an information system for routine hematology using down-sized computer system. We have used an IBM 486 compatible PC with 16MB main memory, 210 MB hard disk drive, 9 RS-232C port and 24 pin dot printer. The operating system and database management system were SCO UNIX and SCO foxbase, respectively. For program development, we used Xbase language provided by SCO foxbase. The C language was used for interface purpose. To make the system use friendly, pull-down menu was used. The system connected to our hospital information system via application program interface (API), so the information related to patient and request details is automatically transmitted to our computer. Our system interfaced with fwd complete blood count analyzers(Sysmex NE-8000 and Coulter STKS) for unidirectional data tansmission from analyzer to computer. The authors suggests that this system based on down-sized computer could provide a progressive approach to total LIS based on local area network, and the implemented system could serve as a model for other hospital's LIS for routine hematology. 30609 T00401030609 ^x To develop an artificial bone substitute that is gradually degraded and replaced by the regenerated natural bone, the authors designed a composite that is consisted of calcium phosphate and collagen. To use as the structural matrix of the composite, collagen was purified from human umbilical cord. The obtained collagen was treated by pepsin to remove telopeptides, and finally, the immune-free atelocollagen was produced: The cross linked atelocollagen was highly resistant to the collagenase induced collagenolysis. The cross linked collagen demonstrated an improved tensile strength. 30618 T00401030618 ^x This paper is a study on the design of adptive filter for QRS complex detection. We propose a simple adaptive algorithm to increase capability of noise cancelation in QRS complex detection with two stage adaptive filter. At the first stage, background noise is removed and at the next stage, only spectrum of QRS complex components is passed. Two adaptive filters can afford to keep track of the changes of both noise and QRS complex. Each adaptive filter consists of prediction error filter and FIR filter The impulse response of FIR filter uses coefficients of prediction error filter. The detection rates for 105 and 108 of MIT/BIH data base were 99.3% and 97.4% respectively. 30619 T00401030619 ^x To develop an artificial bone substitute that is gradually degraded and replaced by the regenerated natural bone, the authors designed and produced a composite that is consisted of calcium phosphate and collagen. Human umbilical cord origin pepsin treated type I atelocollagen was used as the structural matrix, by which sintered or non-sintered carbonate apatite was encapsulated to form an inorganic-organic composite. With cross linking atelocollagen by UV ray irradiation, the resistance to both compressive and tensile strength was increased. Collagen degradation by the collagenase induced collagenolysis was also decreased. 30620 T00401030620 ^x We have developed a monoleaflet polymer valve as an inexpensive and viable alternative, especially for short-term use in the ventricular assist device or total artificial heart. The frame and leaflet of the polymer valve were made from polyurethane, To evaluate the hemodynamic performance of the polymer valve a comparative study of flow dynamics past a polymer valve and a St. Jude Medical prosthetic valve under physiological pulsatile flow conditions in vitro was made. Comparisons between the valves were made on the transvalvular pressure drop, regurgitation volume and maximum valve opening area. The polymer valve showed smaller regurgitation volume and transvalvular pressure drop compared to the mechanical valve at higher heart rate. The results showed that the functional characteristics of the polymer valve compared favorably with those of the mechanical valve at higher heart rate. 30621 T00401030621 ^x Explosive evaporative removal process of biological tissue by absorption of a CW laser has been simulated by using gelatin and a multimode Nd:YAG laser. Because the point of maximun temperature of laser-irradiated gelatin exists below the surface due to surface cooling, evaporation at the boiling temperature is made explosively from below the surface. The important parameters of this process are the conduction loss to laser power absorption (defined as the conduction-to-laser power parameter, Nk), the convection heat transfer at the surface to conduction loss (defined as Bi), dimensionless extinction coefficient (defined as Br.), and dimensionless irradiation time (defined as Fo). Dependence of Fo on Nk and Bi has been observed by experiment, and the results have been compared with the numerical results obtained by solving a 2-dimensional conduction equation. Fo and explosion depth (from the surface to the point of maximun temperature) are increased when Nk and Bi are increased.To find out the minimum laser power for explosive evaporative removal process, steady state analysis has been also made. The limit of Nk to induce evaporative removal, which is proportional to the inverse of the laser power, has been obtained. 30622 T00401030622 ^x N1 and N2 gross neural action potentials were measured from the round window of the guinea pig cochlea at the onset of the acoustic stimuli. N1-N2 audiograms were made by means of regulating stimulant intensities in order to produce constant N1-N2 potentials as criteria for different input tone pip frequencies. The lowest threshold was measured with an input tone pip I5 dB SPL in intensity and 12 KHz in frequency when the animal was in normal physiological condition. The procedure of experimental measurements is explained in detail. This experimental approach is very useful for the investigation of the Cochlear function. Both noN1inear and active functions of the Cochlea can be monitored by N1-N2 audiograms. 30623 T00401030623 ^x In electrical impedance tomography(EIT), we use boundary current and voltage measurements toprovide the information about the cross-sectional distribution of electrical impedance or resistivity. One of the major problems in EIT has been the inaccessibility of internal voltage or current data in finding the internal impedance values. We propose a new image reconstruction method using internal current density data measured by NMR. We obtained a two-dimensional current density distribution within a phantom by processing the real and imaginary MR images from a 4.77 NMR machine. We implemented a resistivity mage reconstruction algorithm using the finite element method and sensitivity matrix. We presented computer simulation results of the mage reconstruction algorithm and furture direction of the research. 30624 T00401030624 ^x A new method of digital image analysis technique for discrimination of cancer cell was presented in this paper. The object image was the Thyroid eland cells image that was diagnosed as normal and abnormal (two types of abnormal: follicular neoplastic cell, and papillary neoplastic cell), respectively. By using the proposed region segmentation algorithm, the cells were segmented into nucleus. The 16 feature parameters were used to calculate the features of each nucleus. A9 a consequence of using dominant feature parameters method proposed in this paper, discrimination rate of 91.11% was obtained for Thyroid Gland cells. 30625 T00401030625 ^x An electrical stimulator was designed to induce locomotion for paraplegic patients caused by central nervous system injury. Optimal stimulus parameters, which can minimize muscle fatigue and can achieve effective muscle contraction were determined in slow and fast muscles in Sprague-Dawley rats. Stimulus patterns of our stimulator were designed to simulate electromyographic activity monitored during locomotion of normal subjects. Muscle types of the lower extremity were classified according to their mechanical property of contraction, which are slow muscle (msoleus m.) and fast muscle (medial gastrocneminus m., rectus femoris m., vastus lateralis m.). Optimal parameters of electrical stimulation for slow muscles were 20 Hz, 0.2 ms square pulse. For fast muscle, 40 Hz, 0.3 ms square pulse was optimal to produce repeated contraction. Higher stimulus intensity was required when synergistic muscles were stimulated simultaneously than when they were stimulated individually. Electrical stimulation for each muscle was designed to generate bipedal locomotion, so that individual muscles alternate contraction and relaxation to simulate stance and swing phases. Portable electrical stimulator with 16 channels built in microprocessor was constructed and applied to paraplegic patients due to lumbar cord injury. The electrical stimulator restored partially gait function in paraplegic patients. 30626 T00401030626 ^x Two-Dimensional modelling of the Cochlear biomechanics is presented in this paper. The Laplace partial differential equation which represents the fluid mechanics of the Cochlea has been transformed into two-dimensional electrical transmission line. The procedure of this transformation is explained in detail. The comparison between one and two dimensional models is also presented. This electrical modelling of the basilar membrane (BM) is clearly useful for the next approach to the further. Development of active elements which are essential in the producing of the sharp tuning of the BM. This paper shows that two-dimension model is qualitatively better than one-dimensional model both in amplitude and phase responses of the BM displacement. The present model is only for frequency response. However because the model is electrical, the two-dimensional transmission line model can be extended to time response without any difficult. 30627 T00401030627 ^x A method has been proposed for the fully automatic detection of left ventricular endocardial boundary in 2D short axis echocardiogram using geometric model. The procedure has the following three distinct stages. First, the initial center is estimated by the initial center estimation algorithm which is applied to decimated image. Second, the center estimation algorithm is applied to original image and then best-fit elliptic model estimation is processed. Third, best-fit boundary is detected by the cost function which is based on the best-fit elliptic model. The proposed method shows effective result without manual intervention by a human operator. 30628 T00401030628 ^x The intelligent trajectory control method that controls moving direction and average velocity for a prosthetic arm is proposed by pattern recognition and force estimations using EMG signals. Also, we propose the real time trajectory planning method which generates continuous accelleration paths using 3 stage linear filters to minimize the impact to human body induced by arm motions and to reduce the muscle fatigue. We use combination of MLP and fuzzy filter for pattern recognition to estimate the direction of a muscle and Hogan's method for the force estimation. EMG signals are acquired by using a amputation simulator and 2 dimensional joystick motion. The simulation results of proposed prosthetic arm control system using the EMf signals show that the arm is effectively followed the desired trajectory depended on estimated force and direction of muscle movements. 30638 T00401030638 ^x A new neural network architecture for the recognition of patterns from images is proposed, which is partially based on the results of physiological studies. The proposed network is composed of multi-layers and the nerve cells in each layer are connected by spatial filters which approximate receptive fields in optic nerve fields. In the proposed method, patterns recognition for complicated images is carried out using global features as well as local features such as lines and end-points. A new generating method of matched filers representing global features is proposed in this network. 30659 T00401030659 ^x An implementation scheme of the magnetic nerve stimulator using a switching mode power supply is proposed. By using a switching mode power supply rather than a conventional linear power supply for charging high voltage capacitors, the weight and size of the magnetic nerve stimulator can be considerably reduced. Maximum output voltage of the developed magnetic nerve stimulator using the switching mode power supply is 3, 000 volts and switching time is about 100 msec. Experimental results or human nerve stimulations using the developed stimulator are presented. 30768 T00401030768 ^x In this paper, we describe the design methodology and specifications of the developed module-based bedside monitors for patient monitoring. The bedside monitor consists of a main unit and module cases with various parameter modules. The main unit includes a 12.1" TFT color LCD, a main CPU board, and peripherals such as a module controller, Ethernet LAN card, video card, rotate/push button controller, etc. The main unit can connect at maximum three module cases each of which can accommodate up to 7 parameter modules. They include the modules for electrocardiograph, respiration, invasive blood pressure, noninvasive blood pressure, temperature, and SpO2 with Plethysmograph.SpO2 with Plethysmograph.

• 한국우주과학회:학술대회논문집(한국우주과학회보)
• /
• 한국우주과학회 1993년도 한국우주과학회보 제2권2호
• /
• pp.17-17
• /
• 1993

The wall shear stress in the vicinity of end-to end anastomoses under steady flow conditions was measured using a flush-mounted hot-film anemometer(FMHFA) probe. The experimental measurements were in good agreement with numerical results except in flow with low Reynolds numbers. The wall shear stress increased proximal to the anastomosis in flow from the Penrose tubing (simulating an artery) to the PTFE: graft. In flow from the PTFE graft to the Penrose tubing, low wall shear stress was observed distal to the anastomosis. Abnormal distributions of wall shear stress in the vicinity of the anastomosis, resulting from the compliance mismatch between the graft and the host artery, might be an important factor of ANFH formation and the graft failure. The present study suggests a correlation between regions of the low wall shear stress and the development of anastomotic neointimal fibrous hyperplasia(ANPH) in end-to-end anastomoses. 30523 T00401030523 ^x Air pressure decay(APD) rate and ultrafiltration rate(UFR) tests were performed on new and saline rinsed dialyzers as well as those roused in patients several times. C-DAK 4000 (Cordis Dow) and CF IS-11 (Baxter Travenol) reused dialyzers obtained from the dialysis clinic were used in the present study. The new dialyzers exhibited a relatively flat APD, whereas saline rinsed and reused dialyzers showed considerable amount of decay. C-DAH dialyzers had a larger APD(11.70${\pm}$1.32mmHg/min)compared to CF dialyzers(4.32${\pm}$0.55mmHg/min)(p<0.05). However, there was no observable difference in the UFR between the two dialyzers. Neither APD nor UFR showed any significant increase with an increasing number of reuses for up to more than 20reuses. A substantial number of failures observed in APD(larger than 20mmHe/min)on the reused dialyzers(2 out of 40 CP and S out 26 C-DAK) were attributed to the Possible damage on the fibers. The CF 15-11 HFDs which failed APD test did not show changes in the UFR compared to normal dialyzers indicating that APD is a more sensitive test than UFR test to evaluate the integrity of the fibers. 30527 T00401030527 ^x For quantitative measurement of reflected light from a clinical diagnostic strip, a prototype old reflectance photometer was designed. The strip loader and cassette were made to obtain more accurate reflectance parameters. The strip was illuminated at 45˚c through optical fiber and the intensity of reflected light was determined at rectanguLat angle using a photodiode. The kubelka-munk coefficient and reflection optical density were determined ar four different wavelengths(500,550,570 and 610nm) for blood glucose strip. For higher concentration than 300mg/41 about glucose, a saturation state of abforbance was observed at 500,550 and 570nm. The correlation between glucose concentration and parameters was the best at 610nm. 30535 T00401030535 ^x Radiation-induced fibrosarcoma tumors were grown on the flanks of C3H mice. The mice were divided into two groups. One group was injected with Photofrin II, intravenously (2.5mg/kg body weight). The other group received no Photofrin II. Mice from both groups were irradialed for approximately 15 minutes at 100,300, or 500 mW/cm2 with the argon (488nm/514.5 nm), dye(628nm) and gold vapor (pulsed 628 nm) laser light. A photosensitizer behaved as an added absorber. Under our experimental conditions, the presence of Photolfrin II increased surface temperature by at least 40% and the temperature rise due to 300 mW/cm2 irradiation exceeded values for hyperthermia. Light and temperature distributions with depth were estimated by a computer model. The model demonstrated the influence of wavelength on the thermal process and proved to be a valuable tool to investigate internal temperature rise. 30536 T00401030536 ^x We investigated the structural geometry of thirty-eight Korean femurs. The purpose of this study is to identify major geometrical differences between Korean femurs 3nd others that we believe belong to Caucasians so that we would be able to get insights into the femoral component design that fits Asians including Koreans. We utilized computerized tomography (CT) images of femurs extracted from cadavers. The CT images were transformed into bitmap data by using a film scanner, and then analyzed by using a commercially available software called Image v.1.0 and a Macintosh IIci computer.The resulting data were compared with already published data. The major results show that the geometry of the Korean femurs is significantly different from that of Caucasians: (1) the anteversion angle and the canal flare index are greater by the amount of approximately 8˚ and 0.5, respectively, (2) the shape of the isthmus cross section is more round, and (3) the distance between the teaser trochanter and the proximal border of the isthmus is shelter by about 15 mm. The results suggested that the femoral component suitable for Asians should be different from the currently-used components designed and manufactured mostly by European or American companies. 30537 T00401030537 ^x It is well known that nonlinear propagation characteristics of the wave in the tissue may give very useful information for the medical diagnoisis. In this paper, a new method to detect nonlinear propagation characteristics of the internal vibration in the tissue for the low frequency mechanical vibration by using bispectral analysis is proposed. In the method, low frequency vibration of f0( = 100Hz) is applied on the surface of the object, and the waveform of the internal vibration x (t) is measured from Doppler frequency modulation of silmultaneously transmitted probing ultrasonic waves. Then, the bispectra of the signal x (t) at the frequencies (f0, f0) and (f0, 2f0) are calculated to estimate the nonlinear propagation characteristics as their magnitude ratio, w here since bispectrum is free from the gaussian additive noise we can get the value with high S/N. Basic experimental system is constructed by using 3.0 MHz probing ultrasonic waves and the several experiments are carried out for some phantoms. Results show the superiority of the proposed method to the conventional method using power spectrum and also its usefulness for the tissue characterization. 30541 T00401030541 ^x This paper describes the implementation of a computerized radial pulse diagnosis by aids of a clinical expert. On this base, we composed of the radial pulse diagnosis system in korean traditional medicine. The system composed of a radial pulse wave detection system and a radial pulse diagnosis system. With a detection system, we detected Inyoung and Cheongu radial pulse wave and processed it. Then, we have got the characteristic parameters of radial pulse wave and also quantified that according to the method of Inyoung-Cheongu Comparison Radial Pulse Diagnosis. We defined the jugement standard of radial pulse diagnosis system and then we confirmed the possibility for realization of automatic radial pulse diagnosis in korean traditional medicine. 30545 T00401030545 ^x Microspheres are expected to be applied to biomedical areas such as solid-phase immunoassays, drug delivery systems, immunomagnetic cell separation. To synthesize microspheres for biomedical application, "two stage shot growth method" was developed. The uniformity ratio of synthesized microspheres was always smaller than 1.05. And the surface charge density (or the number of ionizable functional groups) of the microspheres synthesized by "two stage shot growth method" was 6~13 times higher than that of the microspheres synthesized by conventional seeded batch copolymerization. As a previous step for biomedical application, adsorption experiments of bovine albumin on microspheres were carried out under various conditions. The maximum adsorbed amount was obtained in the neighborhood of pH 4.5. Isoelectric point of bovine albumin is pH 5.0, so experimental result shows that it shifted to acid area. The adsorption isotherm was obtained, the plateau region was always reached at 2.Og/L (bulk concentration of bovine albumin).The effect of the kind and the amount of surface functional group was also examined. 30575 T00401030575 ^x A medical image workstation was developed using multimedia technique. The system based on PC-486DX was designed to acquire medical images produced by medical imaging instruments and related audio information, that is, doctors' reporting results. Input information was processed and analyzed, then the results were presented in the form of graph and animation. All the informations of the system were hierarchically related with the image as the apex. Processing and analysis algorithms were implemented so that the diagnostic accuracy could be improved. The diagnosed information can be transferred for patient diagnosis through LAN(local area network). 30592 T00401030592 ^x In the conventional infrared imaging system, complex infrared lens systems are usually used for directing collimated narrow infrared beams into the high speed 2-dimensional optic scanner. In this paper, a simple reflective infrared optic system with a 2-dimensional optic scanner is proposed for the realization of medical infrared thermography system. It has been experimentally proven that the intfrared thermography system composed of the proposed optic system has the temperature resolution of 0.1˚c under the spatial resolution of lmrad, the image matrix size of 256 X 240, and tile imaging time of 4 seconds. 30593 T00401030593 ^x In this paper, MIIS (Medical Image Information System) has been designed and implemented using INGRES RDBMS, which is based on a client/server architecture. The implemented system allows users to register and retrieve patient information, medical images and diagnostic reports. It also provides the function to display these information on workstation windows simultaneously by using the designed menu-driven graphic user interface. The medical image compression/decompression techniques are implemented and integrated into the medical image database system for the efficient data storage and the fast access through the network. 30594 T00401030594 ^x In this paper, computerized BEAM was implemented for the space domain analysis of EEG. Trans-formation from temporal summation to two-dimensional mappings is formed by 4 nearest point inter-polaton method. Methods of representation of BEAM are two. One is dot density method which classify brain electrical potential 9 levels by dot density of gray levels and the other is colour method which classify brain electrical 12 levels by red-green colours. In this BEAM, instantaneous change and average energy distribution over any arbitrary time interval of brain electrical activity could be observed and analyzed easily. In the frequency domain, the distribution of energy spectrum of a special band can easily be distinguished normality and abnormality. 30608 T00401030608 ^x Laboratory information system (LIS) is a key tool to manage laboratory data in clinical pathology. Our department has developed an information system for routine hematology using down-sized computer system. We have used an IBM 486 compatible PC with 16MB main memory, 210 MB hard disk drive, 9 RS-232C port and 24 pin dot printer. The operating system and database management system were SCO UNIX and SCO foxbase, respectively. For program development, we used Xbase language provided by SCO foxbase. The C language was used for interface purpose. To make the system use friendly, pull-down menu was used. The system connected to our hospital information system via application program interface (API), so the information related to patient and request details is automatically transmitted to our computer. Our system interfaced with fwd complete blood count analyzers(Sysmex NE-8000 and Coulter STKS) for unidirectional data tansmission from analyzer to computer. The authors suggests that this system based on down-sized computer could provide a progressive approach to total LIS based on local area network, and the implemented system could serve as a model for other hospital's LIS for routine hematology. 30609 T00401030609 ^x To develop an artificial bone substitute that is gradually degraded and replaced by the regenerated natural bone, the authors designed a composite that is consisted of calcium phosphate and collagen. To use as the structural matrix of the composite, collagen was purified from human umbilical cord. The obtained collagen was treated by pepsin to remove telopeptides, and finally, the immune-free atelocollagen was produced: The cross linked atelocollagen was highly resistant to the collagenase induced collagenolysis. The cross linked collagen demonstrated an improved tensile strength. 30618 T00401030618 ^x This paper is a study on the design of adptive filter for QRS complex detection. We propose a simple adaptive algorithm to increase capability of noise cancelation in QRS complex detection with two stage adaptive filter. At the first stage, background noise is removed and at the next stage, only spectrum of QRS complex components is passed. Two adaptive filters can afford to keep track of the changes of both noise and QRS complex. Each adaptive filter consists of prediction error filter and FIR filter The impulse response of FIR filter uses coefficients of prediction error filter. The detection rates for 105 and 108 of MIT/BIH data base were 99.3% and 97.4% respectively. 30619 T00401030619 ^x To develop an artificial bone substitute that is gradually degraded and replaced by the regenerated natural bone, the authors designed and produced a composite that is consisted of calcium phosphate and collagen. Human umbilical cord origin pepsin treated type I atelocollagen was used as the structural matrix, by which sintered or non-sintered carbonate apatite was encapsulated to form an inorganic-organic composite. With cross linking atelocollagen by UV ray irradiation, the resistance to both compressive and tensile strength was increased. Collagen degradation by the collagenase induced collagenolysis was also decreased. 30620 T00401030620 ^x We have developed a monoleaflet polymer valve as an inexpensive and viable alternative, especially for short-term use in the ventricular assist device or total artificial heart. The frame and leaflet of the polymer valve were made from polyurethane, To evaluate the hemodynamic performance of the polymer valve a comparative study of flow dynamics past a polymer valve and a St. Jude Medical prosthetic valve under physiological pulsatile flow conditions in vitro was made. Comparisons between the valves were made on the transvalvular pressure drop, regurgitation volume and maximum valve opening area. The polymer valve showed smaller regurgitation volume and transvalvular pressure drop compared to the mechanical valve at higher heart rate. The results showed that the functional characteristics of the polymer valve compared favorably with those of the mechanical valve at higher heart rate. 30621 T00401030621 ^x Explosive evaporative removal process of biological tissue by absorption of a CW laser has been simulated by using gelatin and a multimode Nd:YAG laser. Because the point of maximun temperature of laser-irradiated gelatin exists below the surface due to surface cooling, evaporation at the boiling temperature is made explosively from below the surface. The important parameters of this process are the conduction loss to laser power absorption (defined as the conduction-to-laser power parameter, Nk), the convection heat transfer at the surface to conduction loss (defined as Bi), dimensionless extinction coefficient (defined as Br.), and dimensionless irradiation time (defined as Fo). Dependence of Fo on Nk and Bi has been observed by experiment, and the results have been compared with the numerical results obtained by solving a 2-dimensional conduction equation. Fo and explosion depth (from the surface to the point of maximun temperature) are increased when Nk and Bi are increased.To find out the minimum laser power for explosive evaporative removal process, steady state analysis has been also made. The limit of Nk to induce evaporative removal, which is proportional to the inverse of the laser power, has been obtained. 30622 T00401030622 ^x N1 and N2 gross neural action potentials were measured from the round window of the guinea pig cochlea at the onset of the acoustic stimuli. N1-N2 audiograms were made by means of regulating stimulant intensities in order to produce constant N1-N2 potentials as criteria for different input tone pip frequencies. The lowest threshold was measured with an input tone pip I5 dB SPL in intensity and 12 KHz in frequency when the animal was in normal physiological condition. The procedure of experimental measurements is explained in detail. This experimental approach is very useful for the investigation of the Cochlear function. Both noN1inear and active functions of the Cochlea can be monitored by N1-N2 audiograms. 30623 T00401030623 ^x In electrical impedance tomography(EIT), we use boundary current and voltage measurements toprovide the information about the cross-sectional distribution of electrical impedance or resistivity. One of the major problems in EIT has been the inaccessibility of internal voltage or current data in finding the internal impedance values. We propose a new image reconstruction method using internal current density data measured by NMR. We obtained a two-dimensional current density distribution within a phantom by processing the real and imaginary MR images from a 4.77 NMR machine. We implemented a resistivity mage reconstruction algorithm using the finite element method and sensitivity matrix. We presented computer simulation results of the mage reconstruction algorithm and furture direction of the research. 30624 T00401030624 ^x A new method of digital image analysis technique for discrimination of cancer cell was presented in this paper. The object image was the Thyroid eland cells image that was diagnosed as normal and abnormal (two types of abnormal: follicular neoplastic cell, and papillary neoplastic cell), respectively. By using the proposed region segmentation algorithm, the cells were segmented into nucleus. The 16 feature parameters were used to calculate the features of each nucleus. A9 a consequence of using dominant feature parameters method proposed in this paper, discrimination rate of 91.11% was obtained for Thyroid Gland cells. 30625 T00401030625 ^x An electrical stimulator was designed to induce locomotion for paraplegic patients caused by central nervous system injury. Optimal stimulus parameters, which can minimize muscle fatigue and can achieve effective muscle contraction were determined in slow and fast muscles in Sprague-Dawley rats. Stimulus patterns of our stimulator were designed to simulate electromyographic activity monitored during locomotion of normal subjects. Muscle types of the lower extremity were classified according to their mechanical property of contraction, which are slow muscle (msoleus m.) and fast muscle (medial gastrocneminus m., rectus femoris m., vastus lateralis m.). Optimal parameters of electrical stimulation for slow muscles were 20 Hz, 0.2 ms square pulse. For fast muscle, 40 Hz, 0.3 ms square pulse was optimal to produce repeated contraction. Higher stimulus intensity was required when synergistic muscles were stimulated simultaneously than when they were stimulated individually. Electrical stimulation for each muscle was designed to generate bipedal locomotion, so that individual muscles alternate contraction and relaxation to simulate stance and swing phases. Portable electrical stimulator with 16 channels built in microprocessor was constructed and applied to paraplegic patients due to lumbar cord injury. The electrical stimulator restored partially gait function in paraplegic patients. 30626 T00401030626 ^x Two-Dimensional modelling of the Cochlear biomechanics is presented in this paper. The Laplace partial differential equation which represents the fluid mechanics of the Cochlea has been transformed into two-dimensional electrical transmission line. The procedure of this transformation is explained in detail. The comparison between one and two dimensional models is also presented. This electrical modelling of the basilar membrane (BM) is clearly useful for the next approach to the further. Development of active elements which are essential in the producing of the sharp tuning of the BM. This paper shows that two-dimension model is qualitatively better than one-dimensional model both in amplitude and phase responses of the BM displacement. The present model is only for frequency response. However because the model is electrical, the two-dimensional transmission line model can be extended to time response without any difficult. 30627 T00401030627 ^x A method has been proposed for the fully automatic detection of left ventricular endocardial boundary in 2D short axis echocardiogram using geometric model. The procedure has the following three distinct stages. First, the initial center is estimated by the initial center estimation algorithm which is applied to decimated image. Second, the center estimation algorithm is applied to original image and then best-fit elliptic model estimation is processed. Third, best-fit boundary is detected by the cost function which is based on the best-fit elliptic model. The proposed method shows effective result without manual intervention by a human operator. 30628 T00401030628 ^x The intelligent trajectory control method that controls moving direction and average velocity for a prosthetic arm is proposed by pattern recognition and force estimations using EMG signals. Also, we propose the real time trajectory planning method which generates continuous accelleration paths using 3 stage linear filters to minimize the impact to human body induced by arm motions and to reduce the muscle fatigue. We use combination of MLP and fuzzy filter for pattern recognition to estimate the direction of a muscle and Hogan's method for the force estimation. EMG signals are acquired by using a amputation simulator and 2 dimensional joystick motion. The simulation results of proposed prosthetic arm control system using the EMf signals show that the arm is effectively followed the desired trajectory depended on estimated force and direction of muscle movements. 30638 T00401030638 ^x A new neural network architecture for the recognition of patterns from images is proposed, which is partially based on the results of physiological studies. The proposed network is composed of multi-layers and the nerve cells in each layer are connected by spatial filters which approximate receptive fields in optic nerve fields. In the proposed method, patterns recognition for complicated images is carried out using global features as well as local features such as lines and end-points. A new generating method of matched filers representing global features is proposed in this network. 30659 T00401030659 ^x An implementation scheme of the magnetic nerve stimulator using a switching mode power supply is proposed. By using a switching mode power supply rather than a conventional linear power supply for charging high voltage capacitors, the weight and size of the magnetic nerve stimulator can be considerably reduced. Maximum output voltage of the developed magnetic nerve stimulator using the switching mode power supply is 3,000 volts and switching time is about 100 msec. Experimental results or human nerve stimulations using the developed stimulator are presented. 30768 T00401030768 ^x In this paper, we describe the design methodology and specifications of the developed module-based bedside monitors for patient monitoring. The bedside monitor consists of a main unit and module cases with various parameter modules. The main unit includes a 12.1" TFT color LCD, a main CPU board, and peripherals such as a module controller, Ethernet LAN card, video card, rotate/push button controller, etc. The main unit can connect at maximum three module cases each of which can accommodate up to 7 parameter modules. They include the modules for electrocardiograph, respiration, invasive blood pressure, noninvasive blood pressure, temperature, and SpO2 with Plethysmograph.