• Composites Research
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• 제36권3호
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• pp.193-198
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• 2023

선박 경량화와 관련하여 기존 복합재료 및 3D 프린트 복합재료를 적용하는 연구가 활발히 진행되고 있다. 염수 환경에 대한 내부식성과 경량화 특성이 있는 복합재료와 우수한 생산성을 가지는 3D 프린팅 기술을 연계한 3D 프린트 복합재료의 선박 및 해양구조물 적용 가능성을 확인하기 위해 시험을 진행하였다. 본 논문에 사용된 3D 프린트 복합재료를 선박 및 해양구조물에 적용하기 위해서는 해양환경에서 노출될 수 있는 온도 환경 영향을 고려해야 한다. 따라서 해양 환경에서 노출될 수 있는 온도인 저온(-50℃), 상온(20℃), 고온(50℃) 환경에서 Carbon + Onyx, Carbon + Nylon, HSHT glass + Onyx, HSHT glass + Nylon 소재의 시편으로 인장시험을 진행하였다. 인장시험 결과, Carbon + onyx 시편이 가장 높은 인장강도를 보였고 HSHT glass + onyx 시편이 가장 높은 인장 변형률을 보였다. 또한 인장 시험 결과 시편을 분석하여 다양한 온도 환경에 노출된 3D 프린트 복합재료 시편의 파손 형상에 대해 분석하였다.

• Journal of Korean Neurosurgical Society
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• 제51권6호
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• pp.374-376
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• 2012

Endovascular embolization is being increasingly used to treat intracranial arteriovenous malformations (AVMs). However, we experienced two patients with retained microcatheters after AVM embolization using Onyx.

• Journal of Korean Neurosurgical Society
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• 제52권5호
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• pp.480-483
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• 2012

The authors present a case of isolated dural arteriovenous fistula (DAVF) in the transverse sinus, which developed six years after microvascular decompression caused by hemifacial spasm via suboccipital craniectomy. The lesion was successfully treated by transarterial embolization using Onyx. We reviewed the related radiologic and therapeutic features of DAVF involving an isolated sinus and described the feasibility of the use of Onyx.

• 한국산학기술학회논문지
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• 제14권11호
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• pp.5809-5818
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• 2013

본 논문에서는 '파이프라인 건전도(Pipeline Soundness)와 특허유효성(Patent Validity)개념을 적용하여 제약기업이 적합한 기술 아웃소싱 대상기업을 선정하기 위한 기술 포트폴리오 방법을 제시하고자 한다. 또한 이를 최근 발표한 Amgen의 Onyx Pharmaceuticals 인수사례에 적용하여 개발된 포트폴리오 분석방법의 실제 적용 가능성을 검토하고 사례기업의 기술아웃소싱 타당성을 분석하기로 한다. 본 연구를 통해 제시된 기술포트폴리오의 사례 적용 분석 결과 Amgen은 주력분야인 Cancer 분야의 특허유효성 개선이 시급한 것으로 분석되었으며 Onyx Pharmaceuticals의 인수를 통해 Cancer 분야의 기술포트폴리오를 안정적인 영역에 도달시킬 것으로 기대된다. Amgen의 실제 Onyx Pharmaceuticals 인수 이유 또한 Cancer 분야의 파이프라인 강화와 의약품 도입이라는 점을 고려할 때 새롭게 개발된 기술포트폴리오 분석방법이 실제사례에 잘 적용됨을 알 수 있었으며, 본 연구를 통해 개발된 기술포트폴리오 분석 방법이 제약기업의 기술현황 파악 및 인수대상기업 선정을 위한 도구로 충분히 활용 가능할 수 있을 것으로 판단된다.

• Journal of Korean Neurosurgical Society
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• 제57권1호
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• pp.54-57
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• 2015

A 66-year-old woman presented with intermittent paraparesis and generalized tonic-clonic seizure. Cerebral angiography demonstrated dural arteriovenous fistula (AVF) involving superior sagittal sinus (SSS), which was associated with SSS occlusion on the posterior one third. The dural AVF was fed by bilateral middle meningeal arteries (MMAs), superficial temporal arteries (STAs) and occipital arteries with marked retrograde cortical venous reflux. Transfemoral arterial Onyx embolization was performed through right MMA and STA, but it was not successful, which resulted in partial obliteration of dural AVF because of tortuous MMA preventing the microcatheter from reaching the fistula closely enough. Second procedure was performed through left MMA accessed by direct MMA puncture following small decortications of cranium overlying the MMA using diamond drill one week later. Microcatheter could be located far distally to the fistula through 5 F sheath placed into the MMA and complete obliteration of dural AVF was achieved using 3.9 cc of Onyx.

• 한국수산과학회지
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• 제36권6호
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• pp.625-631
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• 2003

The aim of the present study was to investigate the ecological relationship between female body size (=shell length) and fecundity in a Korean population of protandric hermaphrodite, Crepidula onyx Sowerby, using 6 reproductive variables (the number of capsules per brood, capsule size, the number of embryos per capsule, total number of embryos per brood, egg size, and larval size). The investigation was based on 32 females, 107 egg capsules, 263 eggs, and 250 veliger larvae sampled in January 2000, from Yangpo, the southeastern coast of Korea. All foregoing reproductive variables, except larval size, were significantly correlated with the female body size (p<0.001$\~0.01$). There was a significant increase both in the number of capsules per brood and the number of embryos per capsule with female body size (p<0.001). Consequently, the fecundity of the female C. onyx increased with female body size to over 14.65 mm (the minimum size of egg brooding in the present study). This investigation, therefore, provides additional evidence that female fecundity of protandric hermaphrodites is positively correlated with female body size.

• Journal of Korean Neurosurgical Society
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• 제59권1호
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• pp.17-25
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• 2016

Objective : Treatment of intracranial dural arteriovenous fistulas (dAVFs) remains a challenge. However, after introduction of Onyx, transarterial approach is the preferred treatment option in many centers. We report our experience of dAVFs embolization with special emphasis on transarterial approach. Methods : Seventeen embolization procedures were performed in 13 patients with dAVFs between Jan 2009 and Oct 2014. Clinical symptoms, location and type of fistulas, embolization methods, complications, radiological and clinical outcomes were evaluated using charts and PACS images. Results : All 13 patients had symptomatic lesions. The locations of fistulas were transverse-sigmoid sinus in 6, middle fossa dura in 4, cavernous sinus in 2, and superior sagittal sinus in 1 patient. Cognard types were as follows : I in 4, IIa in 2, IIa+IIb in 5, and IV in 2. Embolization procedures were performed ${\geq}2$ times in 3 patients. Nine patients were treated with transarterial Onyx embolization alone. One of these required direct surgical puncture of middle meningeal artery. Complete obliteration of fistulas was achieved in 11/13 (85%) patients. There were no complications except for 1 case of Onyx migration in cavernous dAVF. Modified Rankin scale score at post-operative 3 months were 0 in 11, and 3 in 2 patients. Conclusion : Transarterial Onyx embolization can be a first line therapeutic option in patients with dAVFs. However, transvenous approach should be tried first in cavernous sinus dAVF because of the risk of intracranial migration of liquid embolic materials. Furthermore, combined surgical endovascular approach can be considered as a useful option in inaccessible route.

• Journal of Korean Neurosurgical Society
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• 제50권3호
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• pp.260-263
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• 2011

Intracranial dural arteriovenous fistulas (DAVFs) are abnormal arteriovenous connections that lie within the dura. Intraosseous DAVFs involving diploic venous system are extremely rare. A 46-year-old woman presented with headache and right pulsatile tinnitus for three weeks. The tinnitus started after yelling. Digital subtraction angiography revealed DAVF within the basal portion of right parietal bone along the middle meningeal artery (MMA) groove. The fistula was fed by frontal branch of right MMA and drained into right transverse sigmoid sinus junction through dilated middle meningeal vein. The intraosseous DAVF involving diploic vein was successfully obliterated with Onyx embolization via transarterial route.

• Journal of Korean Neurosurgical Society
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• 제58권3호
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• pp.276-280
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• 2015

Tentorial dural arteriovenous fistula (DAVF) is a rare vascular disease, which has high risk of intracranial hemorrhage. We present two cases of tentorial DAVF which were successfully treated with single trial of transarterial embolization using Onyx. We briefly reviewed the types of the tentorial DAVF and strategies of treatment.

• 한국패류학회지
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• 제26권1호
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• pp.45-49
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• 2010

Up until now, we have identified 17 exotic species of Mollusca in Korea. These include Achatina (Lissachatina) fulica, Limax flavus, Limax marginatus, Deroceras reticulatum, Hawaiia minuscula, Zonitoides yessoensis, Zonitoides arboreus, Physa acuta, Pomacea canaliculata, Pomacea insularus, Crepidula (Crepidula) onyx, Mytilus galloprovincialis, Xenotrobus securis, Perna viridis, Argopecten irradians irradians, Pinctada fucata, and Pinctada margaritifera. Among them Achatina (Lissachatina) fulica, Pomacea canaliculata, Pomacea insularus, Argopecten irradians irradians, Pinctada fucata, and Pinctada margaritifera were intentionally introduced, whereas remainings were unintentionally introduced into Korean fauna. These foreign species can be divided into three groups on the basis of their habitats: A. fulica, L. flavus, L. marginatus, D. reticulatum, H. minuscula, Z. yessoensis, and Z. arboreus in terrestrial habitat; P. acuta, P. canaliculata, and P. insularus in fresh water; and C. onyx, M. galloprovincialis, L. fortuneikikuchii, P. viridis, A. irradiansirradians, P. fucata, and P. margaritifera in sea water. Taxanomically, 11 species belong to Gastropoda, whereas 6 species are classified to Bivalvia.