• The Korean Journal of Applied Statistics
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• v.25 no.1
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• pp.115-123
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• 2012

In animal tumorigenicity data, tumor onsets occur at several sites and onset times cannot be exactly observed. Instead, the existence of tumors is examined only at death time or sacrifice time of the animal. Such an incomplete data structure makes it difficult to investigate the effect of treatment on tumor onset times; in addition, such dependence should be considered when censoring due to death is related with tumor onset. A bivariate frailty effect is incorporated to model bivariate tumor onsets and to connect death with tumor. For the inference of parameters, EM algorithm is applied and a real NTP(National Toxicology Program) dataset is analyzed as an illustrative example.

• Korean Chemical Engineering Research
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• v.57 no.5
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• pp.723-729
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• 2019

A theoretical analysis was conducted of convective instability driven by buoyancy forces under transient temperature fields in an annular porous medium bounded by coaxial vertical cylinders. Darcy's law and Boussinesq approximation are used to explain the characteristics of fluid motion and linear stability theory is employed to predict the onset of buoyancy-driven motion. The linear stability equations are derived in a global domain, and then cast into in a self-similar domain. Using a spectral expansion method, the stability equations are reformed as a system of ordinary differential equations and solved analytically and numerically. The critical Darcy-Rayleigh number is founded as a function of the radius ratio. Also, the onset time and corresponding wavelength are obtained for the various cases. The critical time becomes smaller with increasing the Darcy-Rayleigh number and follows the asymptotic relation derived in the infinite horizontal porous layer.

• The Journal of Korean Medicine
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• v.23 no.4
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• pp.73-90
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• 2002

Objectives: This study investigated significant factors that influence functional evaluation of stroke so as to be a fundamental data for estimating prognosis of stroke patients. Methods: 204 patients were studied within 7 days of admission, after the diagnosis of stroke through brain CT scan, brain MRI scan and clinical observations. They were hospitalized in the oriental medical hospital of Dongeui University from February to July in 2001. They were examined at the early stage of onset, after 2 weeks, 4 weeks and 6 weeks, and measured for average mark and the degree of improvement by using the Activity Index. Results: Ischemic stroke, past history of stroke, hypertension, diabetes mellitus, risk factor of obesity, non-professional emergency treatment and hospitalizing time after 1 day from onset, high blood pressure, tachycardia pulse and high blood sugar in abnormal vital sign in acute stage, conscious, cognitive or communication disorder, motor aphasia, dysphagia, constipation for more than 3 days, urinary incontinence, visual field defect, insomnia, and chest discomfort in early stage of onset had a negative influence on functional evaluation. Conclusions: Type of stroke, past history, risk factors, emergency treatment and hospitalizing time after onset, abnormal vital sign and intercurrent symptoms in Acute stage were relevant factors in predicting functional evaluation of stroke.

• Journal of Medicine and Life Science
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• v.20 no.3
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• pp.107-114
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• 2023

Epidemiological control of coronavirus disease 2019 (COVID-19) is needed to estimate the infection period of confirmed cases and identify potential cases. The present study, targeting confirmed cases for which the time of COVID-19 symptom onset was disclosed, aimed to investigate the relationship between intervals (day) from symptom onset to testing the cycle threshold (CT) values of real-time reverse transcription-polymerase chain reaction. Of the COVID-19 confirmed cases, those for which the date of suspected symptom onset in the epidemiological investigation was specifically disclosed were included in this study. Interval was defined as the number of days from symptom onset (as disclosed by the patient) to specimen collection for testing. A locally weighted regression smoothing (LOWESS) curve was applied, with intervals as explanatory variables and CT values (CTR for RdRp gene and CTE for E gene) as outcome variables. After finding its non-linear relationship, a polynomial regression model was applied to estimate the 95% confidence interval values of CTR and CTE by interval. The application of LOWESS in 331 patients identified a U-shaped curve relationship between the CTR and CTE values according to the number of interval days, and both CTR and CTE satisfied the quadratic model for interval days. Active application of these results to epidemiological investigations would minimize the chance of failing to identify individuals who are in contact with COVID-19 confirmed cases, thereby reducing the potential transmission of the virus to local communities.

• Korean Journal of Community Nutrition
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• v.4 no.4
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• pp.489-495
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• 1999

This study was conducted to investigate the weaning practice of 198 infants in Taejon city in October, 1998. Information on infant feeding and weaning practices were obtained by interviewing mothers in gynecologist and pediatric clinics located in Taejon. The results obtained were as follows : In the survey 37.4% of the infants were breast-feeding, while 31.3% of them were bottle-feeding and 29.3% of them were mixed-feeding. The reason for bottled-feeding was due either to the lack of breast-milk secretion or motner’s job. The educational level of the mother and maternal job affected the feeding methods before weaning. Lower rates of breast-feeding were found among mothers witn a lover level of education. The breast-feeding rate was lower in full-time and part-time job worker groups than in housewife. There was no significant difference in the feeding methods according to family income. Among the subjects, 71.5% of infants began to be weaned within 7 months. The onset of weaning was delayed in the full-time worker group. There was no significant difference in the onset time of weaning according to feeding method, the educational level of the mother, and family income. 60.6% of infants received fruit juice and 29.6% of them received cereals for first-given-supplementary food. ‘For baby’s nutritional status’ was the most common motivation for the onset of weaning. Commercially prepared foods were used more than home-made food for supplementary food.

• Journal of the Korean Geographical Society
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• v.43 no.1
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• pp.36-51
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• 2008

As the global warming has influenced on various sectors including agriculture, forestry, fisheries and health, it is essential to project more accurate future climate for an assessment of climate change impact and adaptation strategy. This study examines spatial distribution of onset dates and durations of season decomposed by applying a lowpass filtering using observed 30-year (1971-2000) data and projected 2090s data based on the IPCC SRES A1B emission scenario in South Korea. In general, the distributions of spring and winter onset date are affected by latitudes, topography and proximity to oceans. However, onset dates of summer and autumn are a little affected by proximity to oceans and topography than by latitudes. In the 2090s (2091-2100), the onset dates of spring begin about 40 days earlier and the onset dates of summer begin 25-30 days earlier as compare with present time. On the other hand, the onset dates of winter begin about 50 days later in the southern and eastern coastal area and in the southern inland. The onset dates of autumn begin about 20 days later. In the 2090s, summer duration is longer and winter duration is shorter as compare with present time at southern and eastern coastal area.

• Journal of Korean Physical Therapy Science
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• v.8 no.2
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• pp.1065-1071
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• 2001

Delayed onset muscle soreness is a sensation of discomfort that occurs 24 h after exercise, and it is associated with the performance of unfamiliar and high force muscle work, such as eccentric contractions. The injury to the muscle has been well described but the mechanism underlying the injury is not fully understood. Although the pathophysiological processes underlying delayed onset muscle soreness are not completely understood, many researchers have investigated various treatments in a attempt to reduce the soreness. Physical therapy is the most importance techniques to reduce delayed onset muscle soreness. The purpose of this study is to investigate the effect of a cryotherapt on DOMS. Thirty subjects were randomly assigned to experimental group : control, cryotherapy, and placebo group. Elbow flexion range, mechanical pain threshold. and subjective pain were measured 30 min before DOMS was induced and 24, 48, 72 hours after DOMS was induced. The results of this study were as follows: 1. Elbow flexion range showed significant difference each time, especially at 48 and 72 hours 2. Mechanical pain thershold and subjectively pain showed no significant difference between group.

• Proceedings of the Korean Society of Propulsion Engineers Conference
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• 2006.11a
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• pp.30-33
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• 2006

Onset voltage plays a crucial role in the design of a spray microthruster. This paper presents an analytical electrostatic model to predict the behavior of onset voltage in an array of emitters. The basic idea of this method is to superimpose the electric potentials obtained from each individual emitter in an array of emitters. The results show that if one emitter operates and the other neighboring emitters are dry, the potential required for cone-jet spraying generally increases as the emitter spacing decreases (due to electrical shielding). However at very close spacing the potential can decrease. If all emitters operate at the same time, the phenomenon that even at very close spacing the onset voltage required for cone-jet spraying increases merely as the emitter spacing decreases.

• Survey Research
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• v.11 no.3
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• pp.81-101
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• 2010

The purposes of the present study were to investigate the effects of individual, family, and school factors on the onset of adolescents' violence behaviors. For these goals, we applied discrete-time survival analysis to the Korean Youth Panel Survey. According to the estimated hazard function, the likelihood of onset of adolescents' violence behavior was low during elementary school years and increasing sharply from middle school years. Results showed that gender, self-esteem, aggressiveness, broken home, parental abuse, and the number of delinquent friends were significant determinants of the onset of adolescents' violence behaviors. Findings from this study suggest the need to focus on the significant determinants and consider various prevention programs.

• Journal of the Korean earth science society
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• v.39 no.6
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• pp.593-599
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• 2018

The onset times of P- and S-waves are important information to have reliable earthquake locations, 1D or 3D subsurface velocity structures, and other related studies in seismology. As the number of seismic stations increases significantly in recent years, it becomes a formidable task for network operators to pick phase arrivals manually. This study used a simple method to estimate additional P- and S-wave arrival times for local earthquakes when a priori information (event location and time) is available using the Akaike Information Criterion (AIC). We applied the AIC program to the earthquake data recorded at the seismic station located in Gyeongsan (DAG2). The comparisons of automatically estimated phase arrival times with manually picked onset times showed that 95.1% and 93.7% of P-wave and S-wave arrival time estimations, respectively, are less than 0.1 second difference. The higher percentage of agreement presented the method which can be successfully applied to large data sets recorded by high-density seismic arrays.