• 대한인간공학회지
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• 제28권3호
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• pp.49-54
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• 2009

Visual occlusion method is a visual demand measuring technique which uses periodic vision/occlusion cycle to simulate driving environment. It became one of the most popular techniques for the evaluation of in-vehicle interfaces due to its robustness and cost-effectiveness. However, it has a limitation in that the vision/occlusion cycle forces the user to use the IVIS at a predetermined pace, while a driver decides when to use the device on his/her own in actual driving. This paper proposes a user-driven visual occlusion method for measuring the visual demand of in-vehicle interfaces. An experiment was conducted to examine the visual demand of an in-vehicle interface prototype using both the existing (system-driven) occlusion method and the proposed (user-driven) one. Two in-vehicle tasks were evaluated: address input and radio tuning. The results showed that, for the radio tuning task, there were significant differences in total shutter open time and resumability ratio between the methods. The user-driven visual occlusion method not only allows a better representation of drivers' behavior, but it also seems to provide more information on the chunkability of a task.

• 한국수산과학회지
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• 제28권4호
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• pp.428-434
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• 1995

생선 횟집의 활어용 수조수에 대한 위생 대책 수립의 일환으로 자외선을 이용한 제균 효과를 검토하였다. 1. 물 두께 10mm (유수량: 730ml/sec, 등; 5조, 통과 시간: 2.4초)와 자외선 조사량 75W의 조건에서 자외선 등 통과 직후의 해수에서의 생균수 감소율은 평균 $85.0\%$였다. 2. 장염 비브리오균의 경우, 자외선 조사 후 1시간만에 3 log cycle 감소하였으며, 그 이후 큰 변화가 없었다. 3. 한편 쥐치에 같은 조건으로 72시간 처리했을 때 내장 세균의 감소는 거의 없었으나, 돌돔 및 쥐치의 표피와 아가미에서의 생균수 감소율은 약 2log cycle이었다. 4. 패류의 여수율을 좋게 하기 위하여 수조수의 온도를 $20-23^{\circ}C$로 조절한 수조에서 홍합과 굴을 같은 조건으로 처리했을 때 24시간 후에 생균수의 감소율은 홍합과 굴에서 각각 2 log cycle 정도였으며, 분변계 대장균의 경우는 각각 3 log cycle, 1.5 log cycle 정도 감소하였다.

• 품질경영학회지
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• 제28권3호
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• pp.91-103
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• 2000

It is very important to rationally allocate manufacturing processes because customer's needs are being various, and product life cycle in the market Is being shortened. The process allocation is needed before making process control plan and is mostly being done by the field experience or intuition of machine operator, process engineer and/or maintenance technician. Therefore, a modified allocation method using the process variation is proposed. This paper presents the result of comparative studies between current method and the proposed one.

• 한국경영과학회:학술대회논문집
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• 대한산업공학회/한국경영과학회 1996년도 춘계공동학술대회논문집; 공군사관학교, 청주; 26-27 Apr. 1996
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• pp.225-229
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• 1996

In order to accomplish large-size information systems successfully, one of the most improtant factor is the system integration(SI) of individual software projects which consist of the systems. A developer of each project should consider aspects of SI through the development cycle, and a manager of the entire system should manage, control, and evaluate each from a SI point of view. In this research, management models for the system managers, development models for the developers of unit projects, and standardized output documents for the management and evaluation purpose are presented based on the SI concepts.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 2000년도 제15차 학술회의논문집
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• pp.205-205
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• 2000

In this paper, we are proposed an analysis method of the operation schedule in FMS using Time Petri Nets(TPN) unfolding. TPN's unfolding is one of the analysis methods after changed non-cyclic net from the concurrent net without to expand the state explosion. We are illustrated this proposed to analyze a schedule problem in Ratio-driven FMS modeling.

• Asian Pacific Journal of Cancer Prevention
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• 제14권4호
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• pp.2487-2490
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• 2013

In Thai traditional medicine, Plumbago indica or Jetamul-Pleung-Dang in Thai is known to have health benefit especially for anti-inflammatory, antibacterial, and antitumor activities. However, the mechanisms of its action are still uncertain. One of which might be genotoxic effects. In the present study, we investigated the genotoxicity of an ethanolic extract of Plumbago indica root (EEPIR) by sister chromatid exchange (SCE) assay in human lymphocytes. Results have shown that all treatments with EEPIR ($12.5-100{\mu}g/ml$) could induce cell cycle delay as shown by significant increase in the number of metaphase cells in the first cell cycle but neither in the second nor the third cell cycle. Only at concentrations of 25, 50, and $100{\mu}g/ml$ were SCE levels significantly increased above that of the control (p<0.05). EEPIR at a concentration of $500{\mu}g/ml$ induced cell death as few mitotic cells were shown. Accordingly, EEPIR ($25-100{\mu}g/ml$) is genotoxic in human lymphocytes and cytotoxic at concentrations of ${\geq}500{\mu}g/ml$ in vitro. Therefore, these activities of the EEPIR could serve its potential therapeutic effects, especially as an anticancer agent. Further study of EEPIR in vivo is now needed to support this in vitro evidence.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제12권8호
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• pp.3888-3910
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• 2018

As an increasing number of defense methods against control-data attacks are deployed in practice, control-data attacks have become challenging, and non-control-data attacks are on the rise. However, defense methods against non-control-data attacks are still deficient even though these attacks can produce damage as significant as that of control-data attacks. We present a method to defend against non-control-data attacks using influence domain monitoring (IDM). A definition of the data influence domain is first proposed to describe the characteristics of a variable during its life cycle. IDM extracts security-critical non-control data from the target program and then instruments the target for monitoring these variables' influence domains to ensure that corrupted variables will not be used as the attackers intend. Therefore, attackers may be able to modify the value of one security-critical variable by exploiting certain memory corruption vulnerabilities, but they will be prevented from using the variable for nefarious purposes. We evaluate a prototype implementation of IDM and use the experimental results to show that this method can defend against most known non-control-data attacks while imposing a moderate amount of performance overhead.

• Clinical and Experimental Reproductive Medicine
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• 제24권1호
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• pp.143-151
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• 1997

The present study was designed to investigate if antithyroid antibodies (ATA) could affect the pregnancy outcome in euthyroid women undergoing in vitro fertilization and embryo transfer (IVF-ET). From October 1995 to September 1996, 28 euthyroid women with ATA who underwent IVF-ET were studied. Fifty-one euthyroid women without ATA who underwent IVF-ET served as control. Thyroid peroxidase antibody (TPOA) and thyroglobulin antibody (TGA) were assayed using radio ligand assay kits as ATA. All patients included in study and control groups had only tubal factor in infertility. Long protocol of gonadotropin-releasing hormone agonist (GnRH-a) was used for controlled ovarian hyperstimulation (COH) in all patients. There were no significant differences between study and control groups in patient characteristics such as age, infertility duration and hormonal profile. There were also no significant differences between two groups with respect to the clinical response to COH and IVF results such as number of retrieved oocytes, fertilization rate, number of embryos frozen and number of embryos transfered. There were no correlations between ATA (TPOA and TGA) titers and fertilization rate. The clinical pregnancy rate per cycle seemed to be lower in the study group than in the control group (26.3% vs 39.3%), but the difference was not statistically significant. The biochemical pregnancy rate per cycle and miscarriage rate were significantly higher in the study group at 18.4% (7/38) and 40.0% (4/10) compared with 5.6% (5/89) and 11.4% (4/35) in the control group. In the study group, both TPOA and TGA titers were significantly higher in the biochemical pregnancy group than in the clinical pregnancy group or non-pregnancy group. In 10 women with ATA who achieved pregnancy following IVF-ET, both TPOA and TGA titers were significantly higher in the miscarriage group than in the ongoing or delivery group. In conclusion, euthyroid women with ATA appear to represent a less favorable subset within other tubal factor patients when treated with IVF-ET.

• Asian Pacific Journal of Cancer Prevention
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• 제16권4호
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• pp.1599-1603
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• 2015

Background: Epigenetic silencing of tumor suppressor genes due to promoter hypermethylation is one of the frequent mechanisms observed in cancers. Hypermethylation of several tumor suppressor genes involved in cell cycle regulation has been reported in many types of tumors including oral squamous cell carcinomas. LATS1 (Large Tumor Suppressor, isoform 1) is a novel tumor suppressor gene that regulates cell cycle progression by forming complexes with the cyclin dependent kinase, CDK1. Promoter hypermethylation of the LATS1 gene has been observed in several carcinomas and also has been linked with prognosis. However, the methylation status of LATS1 in oral squamous cell carcinomas is not known. As oral cancer is one of the most prevalent forms of cancer in India, the present study was designed to investigate the methylation status of LATS1 promoter and associate it with histopathological findings in order to determine any associations of the genetic status with stage of differentiation. Materials and Methods: Tumor chromosomal DNA isolated from biopsy tissues of thirteen oral squamous cell carcinoma biopsy tissues were subjected to digestion with methylation sensitive HpaII enzyme followed by amplification with primers flanking CCGG motifs in promoter region of LATS1 gene. The PCR amplicons were subsequently subjected to agarose gel electrophoresis along with undigested amplification control. Results: HpaII enzyme based methylation sensitive PCR identified LATS1 promoter hypermethylation in seven out of thirteen oral squamous cell carcinoma samples. Conclusions: The identification of LATS1 promoter hypermethylation in seven oral squamous cell carcinoma samples (54%), which included one sample with epithelial dysplasia, two early invasive and one moderately differentiated lesions indicates that the hypermethylation of this gene may be one of the early event during carcinogenesis. To the best of our knowledge, this is the first study to have explored and identified positive association between LATS1 promoter hypermethylation with histopathological features in oral squamous cell carcinomas.

• 한국운동역학회지
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• 제14권3호
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• pp.17-35
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• 2004

The purpose of this study is to explain developmental process of gait via angle-angle diagram to understand how coordinated relationships and control change with age. Twenty four female children, from one to five years of age were the test subjects for this study, and their results were compared to a control group consisting of twenty one adult females. The Vicon 370 CCD camera, VCR, video timer, monitor, and audio visual mixer was utilized to graph the gait cycle for all test subjects. Both coordinated Intra-limb relationships, and range of motion and timing according to quadrant were explained through the angle angle diagram. Movement in the sagittal plane showed both coordinated relationships and control earlier than movement in the coronal or transverse plane. In the sagittal plane, hip and Knee coordinated relationships developed first (from one year of age.) Coordinated relationships in the Knee and ankle and hip and ankle developed next, respectively. Both hip and ankle and knee and ankle development were inhibited by the inability of children to completely perform plantar flexion during the swing and initial double limb support phases. Children appeared to compensate for this by extending at their hip joint more than adults during the third phase, final double limb support. In many cases the angle angle diagram for children had a similar shape as adult's angle angle diagram. This shows that children can coordinate their movements at an early age. However, the magnitudes and timing of children's angle angle diagrams still varied greatly from adults, even at five years of age. This indicates that even at this age, children still do not possess full control of their movements.