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가시오가피 추출물의 항산화활성 및 MG-63 조골세포 증식과 alkaline phosphatase 활성에 미치는 효과 (Antioxidant and Cell Proliferation Effects of Acanthopanax senticosus for Extract in Human Osteoblast-like MG-63 Cell Line)

  • 임소영;임재윤;이충수;장여정;박정우;윤선
    • 한국식품과학회지
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    • 제39권6호
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    • pp.694-700
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    • 2007
  • 본 연구에서는 가시오가피 추출물의 부위, 추출 용매, 산 가수분해 전처리에 따른 항산화 활성을 알아보고자 FRAP assay를 실시하였으며, 총 페놀 함량을 측정하고, 가시오가피 추출물의 항산화 활성과 총 페놀 함량간의 상관관계를 분석하였다. 또한 가시오가피 추출물 처리가 조골세포 증식률과 alkaline phosphatase 활성에 미치는 영향을 분석하여 가시오가피의 골다공증 예방 가능성을 규명하고자 하였다. 연구결과 가시오가피에 함유된 총 페놀 함량과 FRAP법으로 측정된 항산화 활성 간에 양의 상관관계가 있는 것으로 나타났으므로, 가시오가피의 항산화 활성은 함유된 폴리페놀에 의해 나타나는 것으로 풀이된다. 그러나 가시오가피에 함유된 폴리페놀 함량과 항산화 활성은 가시오가피의 부위와 추출 용매 및 산 처리 여부에 따라 차이가 나는 것으로 나타났다. 또한 가시오가피의 에탄올 추출물이 물 추출물에 비하여 조골세포 증식을 유의적으로 증가시켜주는 것으로 나타났다. 가시오가피의 물 추출물은 조골세포에서 염기성 인산 분해 효소의 활성을 유의적으로 증가 시켰다. 이는 가시오가피의 부위와 추출 용매 및 전처리 과정에 따라 추출되는 활성 성분의 종류와 양에 차이가 있기 때문으로 풀이된다. 이 결과는 가시오가피의 가공법을 선정하는데 고려되어야 할 중요한 사항으로 사료된다. 본 연구를 통하여 가시오가피의 항산화 활성과 조골세포 증식 효과가 제시되었다. 한국산 가시오가피를 건강 기능 식품 소재로 개발하기 위해서는 동물 실험과 인체 시험을 통한 심도 있는 연구가 수행되어야 할 것이다.

Effects of Dietary Garlic Powder and Copper on Cholesterol Content and Quality Characteristics of Chicken Eggs

  • Lim, K.S.;You, S.J.;An, B.K.;Kang, C.W.
    • Asian-Australasian Journal of Animal Sciences
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    • 제19권4호
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    • pp.582-586
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    • 2006
  • This experiment was conducted to investigate the dietary effect of garlic powder (GP) and copper (Cu) on laying performances and the cholesterol content and quality characteristics of eggs during storage in laying hens. A total of one hundred and eighty, 50-wk-old, Hy-Line Brown layers were divided into 6 groups with 3 replicates per group (10 layers per replicate) and fed one of six diets containing GP 0%, GP 1%, GP 3%, GP 5%, Cu 200 ppm, or GP 3%-Cu 200 ppm for 5 wks. There were no differences in the laying performances and feed intakes bertween treatments. Eggshell strength, eggshell thickness and yolk color were also not affected by feeding of GP and Cu. With increasing dietary GP, Haugh unit was linearly increased after 2 wk of storage (p<0.05). The levels of serum total cholesterol in hens fed diets containing GP or Cu were lower than that of the control (p<0.05), but high density lipoprotein-cholesterol was not influenced by dietary GP or Cu. The content of egg yolk cholesterol from hens fed diets containing GP or Cu was significantly decreased from that of the control, except for the GP 1% group. Based on the results of this experiment, the decrease of Haugh unit during storage was alleviated by feeding of GP. The feeding of GP or Cu alone and in combination altered the cholesterol fractions in serum and reduced the content of egg yolk cholesterol in laying hens.

재성형된 낙동강 모래질 실트의 전단거동 특성 (Characteristics of Shear Behavior of Remolded Nak-dong River Sandy Silt)

  • 김영수;틴킨스웨;김대만
    • 한국지반공학회논문집
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    • 제23권3호
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    • pp.41-50
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    • 2007
  • 본 논문에서는 실트 함유율이 높은 모래에 대한 정규압밀 등방배수 및 비배수 삼축압축시험(NCIU 및 NCID) 결과를 나타내었다. 유효구속응력 $100\sim400kpa$하에서 실트 함유율이 63%인 낙동강 모래 시료를 사용하여 실험을 실시하였다. 실험결과, 모래질 실트는 초기에는 압축이 되지만 전체적인 응력-변형률 곡선에서 최종적으로 체적팽창반응을 보였다. 모래질 실트의 거동은 낮은 소성 특성으로 인하여 점토와 모래보다 비하여 그 특성을 묘사하기가 어려웠다. 특히, 시료는 파괴 후 전단과정에서 팽창현상을 보였다. 모래질 실트의 전단거동과 전단강도정수는 응력-변형률 거동과 Mohr-Coulomb 파괴규준에 의하여 결정되는데, 전단거동은 파괴 후 변형률 연화 경향과 같이 체적변화가 증가하는 것으로 관찰되었다. 본 논문에서 모래질 실트의 전단과정 동안에 발생되는 팽창거동은 모래 함유율 뿐만 아니라 저점착력을 가진 세립자의 함유율에 의해서도 달라졌다.

주제분석기법으로서의 자동색인 (Automatic indexing as a subject analysis technique)

  • 이영자
    • 한국도서관정보학회지
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    • 제12권
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    • pp.61-96
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    • 1985
  • The human subject analysis of a document has some critical problems. The method results in the inconsistency in analysis process and the contradiction of two objects of the subject analysis (one is the identification of the content for the retrieval of specific items and the other is to identify the content for the grouping of related materials). Since the subject analysis by mechanized has been recognized to be the possible way to aggregate the problems of manual analysis, various a n.0, pproaches of automatic indexing have been studied and experimented. This study is to examine the automatic indexing as one of the promising subject analysis techniques by statistical, syntactical and semantic a n.0, pproaches. In conclusion, the reasonable a n.0, pplication time of the automatic indexing should be made a decision based on the through investigation on the cost verse effectiveness, and automatic indexing system should be developed in the close relationship with the on-line search which is a good retrieval system for information explosion society. From now on, since the machine-readable document-text will be envisaged to be more and more available due to the rapid development of computer technology, the more substantial research on the automatic indexing will be also possible, which can bring about the increasing of practical automatic indexing systems.

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흙의 다짐에 관한 연구 (제2 보) -200번체 통과율이 다짐에 미치는 영향- (Study on the Soil Compaction (part II) The Influence of Passing Percentage of No. 200 Sieve on Soil Compaction)

  • 강문묵
    • 한국농공학회지
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    • 제12권1호
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    • pp.1854-1860
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    • 1970
  • Results of this study on the influence of percent passing of No. 200 sieve on soil compaction are as follows; 1. The higher maximum dry density of soil is, the lower optimum moisture content is. Maximum dry density is highest value and optimum moisture content is the lowest value in twocases that percents of No. 200 sieve are 30% in soils of which percents retained on No. 10 sieve are 5% and 10% respectively. 2. Maximum dry density increases according as uniformity coefficient increase. Maximum dry density is the highest when uniformity coefficient is approximately 300 in soil of which maximum diameter is 4.76mm. 3. Maximum dry density has a tendency to become large according as value of Cu Caincrease. Correlation between maximum dry density and $Log_{10}$(CuCa) shows straight line. 4. Maximum dry density increases according as n increase and reaches the peak when n equal 0.35 in condition that the index of talbot formula n is less than 0.35 in soil of which maximum diameter is 4.76mm. 5. Maximum dry density has a tendency to increase according as value of Cg $(Cg=\frac{P_{50}^2}{P_{10}{\times}{P_{200}}$) decrease.

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기초간호과학교육을 위한 웹기반 학습프로그램 개발 및 효과 (Development and Evaluation of a Web-Based Instructional Program on Basic Nursing Science for Nursing Students)

  • 유지수;황애란;홍해숙;박미정
    • Journal of Korean Biological Nursing Science
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    • 제3권2호
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    • pp.63-68
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    • 2001
  • Increasing interest in computer-mediated learning technologies has prompted educators to incorporate them into many learning environments ; however, there is still little evaluative evidence to support their effectiveness. This report describes the development and evaluation of a web-based instructional program on basic nursing science for nursing students. Researcher-designed questionnaires were used to assess the characteristics of our students, and to solicit their ratings of the instructional program on ease of use, accuracy of content, clarity of content, interest, and convenience of the program, using 5-point Likert scales. The respondents indicated that the package was easy and convenient to use, with high technical quality, and of a level challenging to some but not all of the students. On-line quizzes were most highly rated. Also it was confirmed that frequent users of electronic bulletin board showed much higher achievement score than that of nonfrequent users. It was also found that the effect of cyber education was dependent on the active participation of the students. These data suggest that the use of web-based instructional program as a distance education strategy can be an effective method for nursing students and nurses.

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온라인 커뮤니티에서의 건강 관련 콘텐츠 분류 모형 개발 (Development of Classification Model for Healthcare Contents on the Online Community)

  • 김태윤;김유신;최상현;김도훈;장유진
    • 한국정보시스템학회지:정보시스템연구
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    • 제26권4호
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    • pp.285-301
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    • 2017
  • Purpose In this paper we verified the reliabilities of healthcare-related information provided by various users on the site of Naver Jisikin, a Korean typical search platform. Based on Q&A contents we validated answers' reliabilities to the asked questions about a lung cancer with the help of professors at a medical school. Design/methodology/approach The content analysis includes that the types of questions are classified into symptom/diagnosis, therapy, prognosis, after-management and so on. The answers contains advice, advertisement, oriental medicine, and religion as well as the above 5 question categories. The validation results of medical evidence about each answer show that only 49% among all answers have medical grounds. Findings We classified the medical grounded answers into three levels; high, medium and low. Among all answers we need to find out the answers including advertisement because the answers can be harmful to patients. We found the method to select the answers containing advertisement contents with the help of text mining research. The selection model presents high performance as 84% classification accuracy.

웹기반 원격진료시스템에서 암호화인증방식이 적용된 회원관리기법 (Web Based Tele-Medicine System including Security Scheme)

  • 김석수
    • 융합보안논문지
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    • 제5권1호
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    • pp.19-27
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    • 2005
  • 이 연구는 인터넷 기반에서의 3자(환자, 의사, 약사)간의 상호대화형 원격진료 시스템 구현으로서, 효율적인 진료와 빠른 처리를 위한 전자진료차트 및 자료처리에 관한 내용을 제시하고 있으며, 데이타베이스 구축은 IIS 4.0 웹서버 상에서 ASP와 SQL을 연동하여 구현하였으며, 온라인 및 오프라인 겸용모드의 효율적인 자료처리를 위한 시스템 통합과 환자와 의사간의 상담, 그리고 오프라인 상에서의 진료와 환자가 지정한 약사로의 처방전 전송 및 조제, 그리고 진료데이터의 저장 및 검색으로 인한 반영구적인 진료데이터저장, 환자 및 의사의 이 진료데이터를 이용한 보다 정확한 진료 및 처방 등이 가능하도록 하였다. 그리고, 일반회원 및 유료회원, 의사와 악사간의 데이터처리를 각각 등급을 나누어 다르게 하고 있으며, 이에 따른 서비스 접근권한이 부여되기에 각 회원들의 인증이 반드시 뒤따르게 하였다.

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A Review: Influences of Pre-slaughter Stress on Poultry Meat Quality

  • Ali, Md. Shawkat;Kang, Geun-Ho;Joo, Seon Tea
    • Asian-Australasian Journal of Animal Sciences
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    • 제21권6호
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    • pp.912-916
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    • 2008
  • Pre-slaughter conditions affect poultry meat quality. Therefore, stresses before slaughter like heat stress, struggle and shackling on the shackle line, crating and transport and feed withdrawal are very important for the poultry industry in respect of quality as well as welfare of the birds. However, exposure to heat in oxidative stress can in turn lead to cytotoxicity in meat type birds. Chickens exposed to heat stress before slaughter showed the lowest ultimate pH and birds shackled for a longer time the highest. The abdominal fat content was higher in heat stressed birds. Struggling on the shackle line hastened the initial rate of the pH drop and increased the redness of breast meat. Again, with increasing struggling activity, lactate concentration in breast muscle of chicken increased. Paler meat was found in birds that were transported for a longer time than in those after a small journey or not transported. The pre-slaughter and eviscerated weights were decreased as the length of feed withdrawal period increased.

The Role of Charge and Retention in Effective Wet end Management

  • Rantala, T.;Nokelainen J.;Ojala, T;Dr. Taina Sopenlehto
    • 한국펄프종이공학회:학술대회논문집
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    • 한국펄프종이공학회 2000년도 제26회 펄프종이기술 국제세미나
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    • pp.1-10
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    • 2000
  • The development of paper machines, increasing machine speeds with new, mostly low basis weight and/or high ash content paper grades, as well as the fact that several trends regarding process items have increased the sensitivity of papermaking. At the same time, papermakers are looking for flexibility in the production line. We can say that with all PMs the biggest benefits with the lowest capital spending can be achieved by focusing on improved wet end management. In order to manage wet end chemistry on a paper machine, our goal is to control sub-process through which we can influence the operation of the entire wet end with maximum effect. Key measurements and controls are-white water consistency control which is the most effective way to control retention - charge demand measurement and control which takes care of concentration of the anionic material entering to PM -ash measurements and controls which are deeply related to retention and paper quality This paper presents and concentrates to two of these key controls ; retention and charge. The purpose of charge control is to give the process control the tools to react to changes caused by amount of dissolved and colloida material incoming to wet end system. It is called coagulation or fixing control. Retention control is then taking care of retention aid flow to the process by responding any changes seen in white water consistency. It is called flocculation control. Each of these solutions separately , and even more effectively all together, stabilize the wet end operations and so greatly improve the produced paper quality and machine runnability. Practical results will be presented and they are referring to the latest mill cases. We have developed the first wet end measuring system in the late 1980s and control solutions based on this modern measuring technology were completely updated in 1990s. This paper introduces the principle, operation , and results of our unique wet end analyzers (retention and charge ) which are at the level of automation solutions as a part of paper machine quality control Especially our newest member of the platform , on-line charge analyzer has reached and set new standards to the on-line charge monitoring.