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Regulation of Quinone Reductase Activity in Mice by Dehydroglyasperin C Isolated from Licorice (감초에서 분리된 데하드로글라이아스페린 C에 의한 마우스 모델계에서 quinone reductase 활성의 조절)

  • Han, Jung-Hwa;Kim, Jong-Sang
    • Current Research on Agriculture and Life Sciences
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    • v.31 no.1
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    • pp.51-55
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    • 2013
  • Licorice, Glycyrrhizae radix, is one of the oldest and most frequently used botanicals in the oriental medicine. Our previous study showed that dehydrolyasperin C (DGC) isolated from licorice had antioxidant activity and induced phase 2 detoxifying enzymes in mouse hepatoma cells. Therefore, this study was conducted to investigate the effect of exposure time to DGC on quinone reductase (QR), one of the anticarcinogenic biomarkers, and antioxidant potential of plasma using animal model. ICR mice were divided into 7 groups, in which mice in each group were injected with DGC (5 mg/kg b.w.) for 0, 2, 4, 6, 8, 12, 24 hours respectively. Following the treatment the organs including liver, kidney, lung, stomach, large intestine, small and large intestines were collected and subjected to QR activity assay, western blotting, and FRAP assay. Exposure to DGC caused a significant induction of QR activity in stomach and large intestine of mice. Ferric reducing activity of plasma, a typical biomarker for antioxidative potentialshowed that DGC improved antioxidant potential in mice. However, no significant effect of DGC was observed in the other organs.

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Effects of Planting Density on Agronomic Traits and Yield in Bupleurum falcatum L. (시호(柴胡)의 재식밀도(栽植密度)가 생육(生育)과 수량(收量)에 미치는 영향(影響))

  • Kim, Young-Guk;Bang, Jin-Ki;Yu, Hong-Seob;Lee, Seoung-Tack
    • Korean Journal of Medicinal Crop Science
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    • v.5 no.1
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    • pp.67-71
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    • 1997
  • Bupleurum falcatum is one of the oldest medicinal crop spontaneously generated as well as cultivated by man and successfully grown during the summer season in Korea. This study was conducted to examine the effect of planting density in the row spacing and hill spacing system using machine seeder on major agronomic traits, yield and labor saving. In 1993 and 1994, a spilt plot design was used with row spacing as the main plot and hill spacing as subplot. Labor saving efficency of the machine seeder reduced 96% than the hand seeding in sowing time required. Number of seeding stand increased, but stem height and number of nodes did not affect with different density in each row and hill spacing. There were reduced with narrow hill spacing on stem diameter, number of branches, shoot weight and root traits. There was no significant interaction between row and hill spacing for any major traits studied except shoot weight. Yield was more increase at 20cm than at 30cm row spacing. For these studies the optiomum density appears to be between drilling or 5cm hill spacing with 20cm row spacing. A highly significant positive correlation was appeared between number of seedling stand and root yield.

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Oak Forests of the Daegok-cheon Petroglyphs Area in Ulsan, South Korea (울산 대곡천 암각화 유적지 일대의 참나무림 다양성과 분포 특성)

  • Lee, Gyeong-Yeon;Kim, Jong-Won
    • Korean Journal of Ecology and Environment
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    • v.50 no.1
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    • pp.126-136
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    • 2017
  • We describe characteristics of diversity and distribution of oak forests on the Daegok-cheon gorge of the Southeastern Korean Peninsula, the oldest prehistoric site, in view of a sort of food resources of acorns. The $Z{\ddot{u}}rich$-Montpellier School's method was adopted for field investigation on the oak dominant stands. A total of 20 phytosociological $relev\acute{e}s$ composed of 193 taxa were analyzed by syntaxonomy and ecological flora. The Daegok-cheon's oak forests occupied 36.9% ($513,374m^2$) of the surveyed area, and its 99% ($507,677m^2$) was Quercus variabilis and Q. serrata stands. Oak forests of the Daegok-cheon gorge are a kind of regional vegetation type characterizing by the high relative net contribution degree (r-NCD) of Platycarya strobilacea and Sapium japonicum, which are an edaphic type of the xerophilous and thermophilic oak forests. The region of the Daegok-cheon petroglyphs is defined as an ecoregion with rich acorn supply and abundant water resources, and the warmer environment, which attracts prehistoric man.

Financing and Knowledge Accumulation in the Film Industry: Spatial Characteristics of Korean and American Film Industry (영화산업의 자본조달구조와 지식축적과정에 대한 공간적 고찰: 한국과 미국 영화산업의 비교를 통하여)

  • Chung, SunWha
    • Journal of the Economic Geographical Society of Korea
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    • v.20 no.4
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    • pp.453-485
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    • 2017
  • One of the oldest chestnuts in economic geography is this: Cultural and creative industries strongly gather in large cities and this geographic concentration of economic activities leads to regional development. Of course, depending on the circumstances, such a proposition still holds good. But, under the current paradigm shift to knowledge-based economy, it may be open to question. This study aims to investigate financing and knowledge accumulation in the film industry through an alternative framework for explaining their spatial distributions, "formation mechanism of economic space." From the fact that their production organizations are formed on a project basis, project-based financing structure in the investment stage and knowledge accumulation process in the production stage form both axes of it. Film industry as the most mature industry among the cultural and creative industries does not always concentrate in a certain place (industrial agglomeration) or show metropolis-oriented preference. This allows us to reconsider our long brooding theory.

Studies on Damage Characteristics of Gyeongju Bunhwangsa Stone Brick Pagoda (경주 분황사 모전석탑의 손상 특성 연구)

  • Do, Jin Young;Kim, Jeong Jin
    • Journal of the Mineralogical Society of Korea
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    • v.31 no.3
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    • pp.149-159
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    • 2018
  • The Gyeongju Bunhwangsa Stone Brick Pagoda, which was built with bricks of andesite, is the oldest brick stone pagoda of Silla period. The damage patterns in the stone pagoda are pollutants such as white crust, black crust, discoloration, soil adsorption, and microorganisms, and repair materials. The damage pattern of structural factors in the Stone Brick Pagoda is a bulging phenomenon. According to the X-ray diffraction analysis, white crust are mainly consist of calcite ($CaCO_3$) and thermonatrite ($Na_2CO_3{\cdot}H_2O$) that evaporite finds in nature. Damage pattern varies depending on location of stone pagoda. The pollutants are first story body of pagoda. The microorganisms are confirmed at base, lion statues, first and second story capstone, and repair materials observed at base. The bulging phenomenon appeared on the first story body of the pagoda. Occupancy rates by damage type were higher in the order of microorganisms, pollutants, repair material, bulging phenomenon, and peeling. The highest percentage of individual damage patterns were black microorganisms (39.3%), followed by lichen (17.9%), discoloration (8.0%), white crust (5.5%), cement mortar (5.1%) and peeling (3.1%).

Parenthood (어버이살이)

  • Cho, Doo-Young
    • Korean Journal of Psychosomatic Medicine
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    • v.5 no.1
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    • pp.3-11
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    • 1997
  • In becoming parents, the marital partners enter into a new developmental phase. The conception of the child is an act of mutual creativity during which the boundaries between the self and another were temporarily obliterated more completely than at any time since infancy. The infant is a physical fusion of the parents, and their personalities unite within the child. for many women, creativity as a mother becomes a central matter that provides meaning and balance to their lives. The husband usually has strong desires for an offspring and can be transformed by it. The child can profoundly affect one or both parents, and the influences are reciprocal-a child's needs or specific difficulties uncover a parent's inadequacy. following the child's development, each transition into a new developmental phase requires an adaptation by the parents, and one or another of these required adaptations may disturb a parent's equilibirium. And the personality changes, emotional difficulties, and regressions of a spouse that occur in response to some phase of parenthood can upset the marriage. Not only do children identify with parents, but parents also identify with their children. The parents take pleasure in child's joy and suffer with the child's pain more than in almost any other relationship. certain respects e parents lives again in the child. Through the process of identification the child can also provide one of the two parents with the opportunity to experience intimately the way in which a person of the opposite gender grows up. Parenthood also provides the opportunity to be loved, admired, and needed simply because one is a parent and, as such, a central and necessary object in the young child's life. The many potentialities for emotional satisfactions from parenthood manage to outweigh the tribulations and sacrifices that are required. The child also exerts an indirect effect through changing the parent's position in the society, for new sets of relationships are established as the parents are drawn to other couples with children of the same age, and for a new impetus toward economic and social mobility often possesses the parents. frequently the couple's relatedness to their own parents improves and grows firmer once again. Parenthood, the satisfactions it provides and the demands it makes, varies as life progresses : and changes with the parent's interests, needs, and age as well as with the children's maturation. There are phases in the child's life that the parents are reluctant to have pass, whereas they tolerate others largely through knowing that they will soon be over. The changing lives of the children provide many satisfactions that offset the tribulations, uncertainties, and regrets. The parents change. The young father, who was just starting on his carrier whom the first child was born, settles into a life pattern. He becomes secure with increasing achievement and interacts differently with the youngest child and provides a different model for him than for the oldest. The mother may have less time for a second or third child than for her first, but she may also be more assured in her handling of them. The birth of a baby when the parents art in their late thirties will find them Less capable of physical exertion with the child and less tolerant of annoyances, but they are less apt to be annoyed. Eventually the children min and leave home, but the couple do not cease to be parents.

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The Vegetational and Environmental History of the Pre-Holocene Period in the Korean Peninsula (한반도 식생 및 환경변천사(홀로세 이전 시대를 중심으로))

  • Kong, Woo-Seok
    • The Korean Journal of Quaternary Research
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    • v.6 no.1
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    • pp.1-11
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    • 1992
  • The reconstruction of the vegetational and environmental history of the Korean peninsula by the use of various fossil floral data from the Carboniferous period to the Pre-Holocene is reviewed. Though the oldest plant fossil in Korea (Neuropteris) dates back to the Carboniferous period, the first appearance of many of the present-day floristic genera indeed dates back to the Oligocene (c. 40 to 20 million years B.P.), and includes many thermophilous genera. The presence of thermophilous genera in the Oligocene at up to four degrees north of their present distributional limits implies that the climate of the Oligocene was warmer than that of today. The occurrence of similar thermophilous floristic element at up to six degrees north of their present range during the Middle Miocene suggests a maximum northward expansion of warmth-loving evergreen broadleaved vegetation for, recent Korean vegetation history. The continued occurrence of numerous present-day genera since the Oligocene period indicates a long-term stability of Korean vegetation, along with minor fluctuations within it. The admixture of evergreen coniferous plants and deciduous breadleaved plants, however, indicates a probable temperate climate for much of the Middle Pleistocene. There are couple of evidences which are indicative of an early-stage anthropogenic disturbance of natural vegetation during the Middle Pleistocene of Korea. The presence of cold-episodes during the Upper Pleistocene caused a general expansion of deciduous plants and cryophilous evergreen coniferous, plants. It is likely that the maximum southward expansion of cryophilous arctic-alpine and alpine floras in Korea occured during the penultimate glacial period. The disappearance of some cryophilous genera from 10,000 years B.P. marks the continued climatic amelioration since then, along with minor climatic fluctuations during the Holocene period.

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Interpretation of Sedimentary Structure and Depositional Environment Based on a High-Resolution Seismic Profile across the Northeastern Boundary of the Pungam Basin (고해상도 탄성파자료를 이용한 풍암분지 북동부의 퇴적구조 및 퇴적환경 연구)

  • Kim, Gi Yeong;Heo, Sik
    • Journal of the Korean Geophysical Society
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    • v.2 no.2
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    • pp.91-99
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    • 1999
  • A high-resolution seismic profile acquired across the northeastern boundary of the Pungam Basin, one of the Cretaceous sedimentary basins in Korea, has been interpreted to delineate subsurface geological structures across the basin boundary. We identified boundary faults and unconformity surfaces of the basin and divided sediment body into three seismic depositional units (Units I, II, and III from youngest to oldest). Inferred from fault geometry and type, northeastern part of the Pungam Basin has been formed by a strike-slip fault whereas the normal faults near the boundary were formed by transtensional movement along a fault zone. A 350-400 m thick sediment layer is overlying the Precambrian gneiss. Bedding planes of Unit III are dipping westward and are closely related to an anticline in the acoustic basement. Unit II is also tilted westward, suggesting that the eastern part of the fault zone was uplifted after deposition of lower part of the sedimentary body. Afterward, the uplifted sediment layers were eroded and transported to the western part of the basin. Chaotic reflection pattern of sedimentary Units II and III may suggest that strike-slip movement along the fault zone deformed basin-filled sediments.

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Age and Growth of Small Yellow Croaker, Larimichthys polyactis in the South Sea of Korea (한국 남해 참조기의 연령과 성장)

  • Kim, Yeong Hye;Lee, Sun Kil;Lee, Jae Bong;Lee, Dong Woo;Kim, Young Seop
    • Korean Journal of Ichthyology
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    • v.18 no.1
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    • pp.45-54
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    • 2006
  • Age and growth of the small yellow croaker, Larimichthys polyactis were estimated using right sagittal otoliths of 506 fish specimens from March to December, 2002 and from January to February, 2005 in the South Sea, part of the East China Sea of Korea. Examination of outer margins of the otolith showed that the opaque zone was formed once a year. Marginal increment of the otolith formed annual rings from May and June at the beginning of spawning season. In the relationship between total length and body weight, a multiplicative error structure was assumed because variability in growth increased as a function of the length, and the estimated equation was $BW=0.0044TL^{3.2502}$ ($R^2=0.97$). The relative growth as body weight at total length has significant difference between females and males (P<0.05). For describing growth of the small yellow croaker, Larimichthys polyactis a von Bertalanffy growth model was adopted. The von Bertalanffy growth curve had an additive error structure and the growth parameters estimated from non-linear regression were $L_{\infty}=33.88cm$, K=0.20/year and $t_0=-2.39year$. Growth at age of males and females shows no significant difference (P>0.05). Most examined fish were 1, 2 and 3 years old, although the oldest fish were 7 old for males and 8 for females.

Age and Growth of Epinephelus akaara in the South Western Sea of Korea (한반도 서남 연안 붉바리(Epinephelus akaara)의 연령과 성장)

  • Lee, Tae-Won;Lee, Chang-Gyu
    • Korean Journal of Ichthyology
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    • v.8 no.2
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    • pp.16-22
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    • 1996
  • Age and growth of Epinephelus akaara were determined using samples collected from the south western sea of Korea. Thin - sectioned otoliths showed relatively well defined annuli when examined under dark - field microscope. Because the fish do not feed at the temperature under $10^{\circ}C$, the annuli in otoliths are considered to be formed during the period between December and April. Considering that the peak spawning season is July, the first annulus must have been formed in 0.5 year after birth. The oldest fish examined was 9 years old, and the largest one was 47cm. The body length(L, cm) was linearly related to the otolith radius (R, ${\mu}m$) : L= - 2.84+7.01 R. Back-calculated lengths for each age using the relationship between body and otolith size were well adjusted to the Von Bertalanffy growth curve : $L_t$=55.5[1-exp{-0.162(t+0.128)}]. Using relationship between length and weight ($W_t$=0.00608$L^{3.21}$), growth in weight was expressed by Wt=2409(1-exp{-0.162(t+0.128)}]$^{3.21}$.

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