• Clinical and Experimental Reproductive Medicine
• /
• v.45 no.3
• /
• pp.129-134
• /
• 2018

Objective: In frozen and thawed embryos, the zona pellucida (ZP) can be damaged due to hardening. Laser-assisted hatching (LAH) of embryos can increase the pregnancy rate. This study compared thinning and drilling of the ZP before frozen embryo transfer (FET). Methods: Patients were randomly allocated into two groups for LAH using thinning or drilling on day 2 after thawing. Twenty-five percent of the ZP circumference and 50% of the ZP thickness was removed in the thinning group, and a hole $40{\mu}m$ in diameter was made in the drilling group. Results: A total of 171 in vitro fertilization/intracytoplasmic sperm injection FET cycles, including 85 cycles with drilling LAH and 86 cycles with thinning LAH, were carried out. The thinning group had a similar ${\beta}$-human chorionic gonadotropin-positive rate (38.4% vs. 29.4%), implantation rate (16.5% vs. 14.4%), clinical pregnancy rate (36.0% vs. 25.9%), miscarriage rate (5.8% vs. 2.4%), ongoing pregnancy rate (30.2% vs. 23.5%), and multiple pregnancy rate (7.0% vs. 10.6%) to the drilling LAH group. There were no significant differences in pregnancy outcomes between subgroups defined based on age (older or younger than 35 years) or ZP thickness (greater or less than $17{\mu}m$) according to the LAH method. Conclusion: The present study demonstrated that partial ZP thinning or drilling resulted in similar outcomes in implantation and pregnancy rates using thawed embryos, irrespective of women's age or ZP thickness.

• Journal of the Korean Society of Radiology
• /
• v.15 no.6
• /
• pp.861-867
• /
• 2021

Since SBRT takes up to 1 hour from 30 minutes to treatment fraction once or three to five times, there is a possibility of setup error during treatment. To reduce these set-up errors and give accurate doses, we intend to evaluate the usefulness of pre-treatment and post-treatment error values by imaging CBCT again to determine postural movement due to pre-treatment coordinate values using pre-treatment CBCT. On average, the range of systematic errors was 0.032 to 0.17 on the X and Y,Z axes, confirming that there was very little change in movement even after treatment. Tumor centripetal changes (±SD) due to respiratory tuning were 0.11 (±0.12) cm, 0.27 (±0.15) cm, and 0.21 cm (±0.31 cm) in the X, Y and Z directions. The tumor edges ±SD were 0.21 (±0.18) cm, 0.30 (±0.23) cm, and 0.19 cm (±0.26) cm in the X, Y and Z directions. The (±SD) of tumor-corrected displacements were 0.03 (±0.16) cm, 0.05 (±0.26) cm, and 0.02 (±0.23) cm in RL, AP, and SI directions, respectively. The range of the 3D vector value was 0.11 to 0-.18 cm on average when comparing pre-treatment and CBCT, and it was confirmed that the corrected set-up error was within 0.3 cm. Therefore, it was confirmed that there were some changes in values depending on some older patients, condition on the day of treatment, and body type, but they were within the significance range.

• 한국노년학
• /
• v.38 no.4
• /
• pp.853-869
• /
• 2018

This study aimed to investigate variables affecting subjective memory impairment in the elderly with benign prostatic hyperplasia. We used 179 survey data collected from the urology department of two metropolitan general hospitals. The subjects were patients with benign prostatic hyperplasia. T-test, one-way analysis of variance, and $Scheff{\acute{e}}^{\prime}s$ test were performed to identify differences among variables. Pearson's correlation-coefficient and stepwise multiple regression were used to identify variables that affect subjective memory impairment. This study revealed that lower urinary tract symptom and activities of daily living were statistically significant variables, with an explanatory power of 30.0%. The lower urinary tract symptom was due to the benign prostatic hyperplasia increasing the risk of subjective memory impairment. Treatment of the lower urinary tract symptom was delayed because as the elderly got older, they increasingly recognized benign prostatic hyperplasia as a reasonable symptom. Timely intervention and early screening are necessary to prevent lower urinary tract symptom. Finally, programs to reduce the incidence of lower urinary tract symptom and educate nurses to assess, evaluate, perform intervention for subjective memory impairment should be developed.

• Journal of Digital Convergence
• /
• v.19 no.2
• /
• pp.315-322
• /
• 2021

The purpose of this study was to examine the correlations of oral myofunction and oral environment for the elderly with systemic diseases and to suggest need to improve oral health for the elderly. Data were collected from 64 elderly over the age of 65, from April to June 2019. Data were surveyed on general characteristics, oral myofunction, oral health-related quality of life, oral bacteria. Analysis was performed using PASW Statistics ver 18.0. The subjects were 43.8% systemic diseases, among them 40.6 percent of the people with more than two. The number of functional teeth was 18.6. Age was negatively correlated with functional teeth(r=-.384, p<.01) and tongue pressure (r=-).104, p<.001). Tongue pressure was a positive correlation with lip force(r=.279, p<.05). Age and total number of bacteria was negative correlation(r=-.336, p<.01). The functional teeth and total number of bacteria was positive correlation(r=.551, p<.001). The number of systemic diseases and total number of bacteria was positive correlation(r=.327, p<.01) the analysis of oral myofunction and oral bacteria in older patients with systemic diseases It was meaningful in suggesting a plan to improve oral health for the elderly. A practical policy plan was required to improve the quality of oral health life in a super-aged society.

• Pediatric Gastroenterology, Hepatology & Nutrition
• /
• v.24 no.2
• /
• pp.218-229
• /
• 2021

Purpose: Serological tests of tissue transglutaminase (TTG) and deamidated gliadin (DGP) antibodies for celiac disease diagnosis show conflicting correlation with histology in young children and in type 1 diabetes mellitus (T1DM). Tests' ability to predict histology and cutoff values based on age and T1DM was evaluated. Methods: A retrospective study of children who had celiac serological tests between 6/1/2002 and 12/31/2014 at a pediatric hospital. Results: TTG IgA displayed similar results in predicting histology between <4.0 and ≥4.0 years age groups with sensitivity 98% and 93%, and specificity 88% and 86%, respectively. In children <4.0 years old, sensitivity for DGP antibodies was 100% and specificity 94%; in ≥4.0 years age groups, sensitivity was 60%, 88% for DGP IgA and IgG and specificity 95%, 96%, respectively. TTG IgA had low specificity in patients with T1DM compared with non-T1DM, 42% vs. 91%. Positive TTG IgA with normal histology was associated with higher T1DM prevalence at 36% compared with negative tests at 4%. Finally, the TTG IgA cutoff value was higher in T1DM at 36 vs. 16.3 units in non-T1DM. DGP IgG cutoff showed similar values between age groups; TTG IgA and DGP IgA cutoffs were lower in <4.0 years at 8.3 and 11.9 units than ≥4.0 years at 23.4 and 19.9, respectively. Conclusion: TTG IgA is sufficient for the <4.0 years age group and DGP antibodies had no advantage over TTG IgA in older children. The cutoff value to determine a positive TTG IgA should be higher for children with T1DM.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.22 no.3
• /
• pp.169-180
• /
• 2021

This study was undertaken to determine the degree of quality of life, and factors influencing osteoarthritis in hypertensive elderly 65 years or older patients, using data from the 7th National Health and Nutrition Survey 2018. Totally, 843 subjects were included from a national sample. The SPSS WIN 26.0 program was used to analyze complex samples by applying the Rao-Scott chi-square test, t-test, and multiple regression analysis. Results indicate that quality of life of the hypertensive group with osteoarthritis is significantly lower than the group with only hypertension (t=5.07, p<0.001). Factors affecting the decrease in quality of life of the hypertensive group were age, subjective health status, and activity restrictions, and the explanatory power was 46.1% (F=12.33, p<0.001). In the hypertensive group with osteoarthritis, the effective factors included gender, cohabitation status, economic activity, subjective health status, activity restriction, body mass index, sleep time, stress perception, and depression, and the explanatory power was 44.6% (F=99.82, p<0.001). Subsequent studies showed that in order to improve the quality of life of hypertensive seniors, intervention programs are required to actively accommodate health conditions and minimize activity restrictions. In addition, for the elderly with osteoarthritis and hypertension, it is necessary to include exercise and nutrition education for body mass index management, and the development and intervention of multidisciplinary participation programs to strengthen mental health.

• The Journal of Korean Academy of Prosthodontics
• /
• v.60 no.3
• /
• pp.239-245
• /
• 2022

Purpose. The purpose of this study was to analyze the frequency and duration of adjustments after delivery of complete denture according to age, sex, arch with complete denture, insurance coverage of a denture, type of antagonist, the experience of wearing denture, the period of edentulism, and the type of denture base. Materials and methods. For 5 years, medical records of patients aged 65 or older who had treated full dentures were assessed for the frequency and duration of follow-up visits after complete denture delivery. Statistical analysis was performed at the 5% level of significance to analyze the correlation between the frequency and duration of follow-up according to sex, insurance coverage, arch with the complete denture, type of denture base, type of antagonist, experience of wearing a denture, age, and healing period. Results. 247 complete dentures were included in this study. The median frequency of follow-up visits was 3, and the median duration of follow-up was 36 days. Lower dentures had significantly higher frequency of follow-up visits than upper dentures (P = .036). According to the type of antagonist, dentures opposing a complete denture had a significantly higher frequency of follow-up visits than dentures opposing a removable partial denture (P = .016). There was no statistically significant difference in the frequency and duration of adjustments after delivery of complete denture by age, sex, insurance coverage, healing period, the experience of wearing a denture, and type of denture base. Conclusion. Within the limitations of the present study, lower complete dentures or dentures opposing a complete denture had an increased frequency of follow-up visits.

• The Journal of the Korea Contents Association
• /
• v.22 no.7
• /
• pp.676-683
• /
• 2022

Minimizing patient movement during CT-guided lung biopsy is an important factor in the procedure. To minimize movement, a vacuum cushion was used to evaluate its effectiveness. The subjects of this study were 116 patients aged 40 years or older who had good coordination with postural fixation and breathing control. Posture measurements were performed in the supine position, prone position, oblique position, and lateral position according to each position of the lung lesion biopsy lesion. Measurement positions were measured in the anterior, posterior, right, and left positions based on the anatomical posture. In the prone position, the mean difference between the non-use and the use of the posterior was 1.7905, and t=2.913 (p<0.01), and the mean difference between the non-use/use was statistically significant. The difference between the unused and used averages of left was 2.4105, and the difference between the left averages was also significant with t=3.684 (p<0.01). The difference between the unused and used averages of the right was 2.3263, with t=3.791 (p<0.01). The mean difference between unused and used is statistically significant. As a result of statistical analysis, the biopsy of the lung lesion using a fixation device showed less movement in all postures. It is considered that it is meaningful in that it is possible to conduct a more accurate biopsy procedure and minimize the patient's posture movement by using a fixation device during the CT-guided biopsy of the lung lesion.

• Therapeutic Science for Rehabilitation
• /
• v.12 no.3
• /
• pp.61-77
• /
• 2023

Objective : This study analyzed the correlation between cognitive function and oral health-related quality of life (OHQoL). Methods : Demographic and clinical characteristics were extracted and utilized for subjects aged 45 years or older who participated in the 8th Korean Longitudinal Study on Aging in 2020. The dependent variable was the Geriatric Oral Health Assessment Index, and the independent variable was the level of cognitive function classified by the Mini-Mental State Examination scores. The analysis method used inverse probability of treatment weighting (IPTW). Then, the association between cognitive function and OHQoL was analyzed by multiple regression analysis. Results : Among the participants, 4,367 (71.40%) had normal cognition, 1,155 (18.89%) had moderate cognitive impairment, and 594 (9.71%) had severe cognitive impairment. As a result of analysis by applying IPTW, there was a negative correlation between the cognitive function group and OHQoL (normal vs. moderate: β = -2.534, p < .0001; normal vs. severe: β = -2.452, p < .0001). Conclusion : After propensity score matching, mild cognitive impairment showed a more negative association than severe cognitive impairment. Therefore, patients with cognitive impairment require oral health management education to improve OHQoL regardless of the level of cognitive impairment.

• The Korean Journal of Nuclear Medicine Technology
• /
• v.28 no.1
• /
• pp.49-56
• /
• 2024

Purpose: When performing nuclear medicine examinations, body wraps or plastic supports are used to support and immobilize the patient's upper extremities to prevent patient safety accidents. However, the existing plastic supports compromised patient and staff safety, including finger entrapment and falls. Moreover, the body wrap provided by manufacturers compromised image quality such as upper extremities cutoff during whole body bone scan. Therefore, a new design of body wrap was developed to improve the issue, and this study aims to evaluate the usability of this medical body wrap. Materials and Methods: To evaluate the usability of the newly designed medical body wrap, a quality assessment of whole body bone scan images and a user satisfaction survey were conducted. Adult patients (male:female=129:152, age: 60.3±12.4 years, BMI: 24.0±4.2) aged 16 years or older who underwent a whole body bone scan during two periods: June to July 2022 (before improvement, n=139) and June to July 2023 (after improvement, n=142) were randomly selected for image quality evaluation. Five radiotechnologists visually evaluated the posterior view of the whole body bone image, including the left and right elbow (2 points), arm (2 points), whether the hand is extended (2 points), whether the hand is included (2 points), and the number of visible fingers (10 points), with a total of 18 points, which were converted to 100 points and analyzed for difference before and after improvement using an independent sample t-test. The user satisfaction questionnaire was evaluated using a 5-point Likert scale among 16 radiotechnologists from three general hospitals who experienced the new body wrap. Results: The image quality assessment was 82.0±13.8 before the improvement and 89.3±10.1 after the improvement, an average of 7.3 points higher, with a statistically significant difference (t=5.02, p<0.01). The user satisfaction survey showed an overall satisfaction rating of 4.1±0.8 for ease of use, 3.8±0.7 for scan preparation time, 3.9±0.7 for patient safety, 3.8±1.2 for scan accuracy, and 4.2±0.7 for recommendation (87.5% questionnaire response rate). Conclusion: The developed body wrap showed higher image quality and user satisfaction compared to the old method. Considering these results, it is deemed that the new body wrap may be more useful than existing methods.