• Asian Pacific Journal of Cancer Prevention
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• 제14권2호
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• pp.947-950
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• 2013

Background: We performed this meta-analysis to assess the effectiveness and safety of axillary dissection in old women. Methods: The Cochrane Library, PubMed, EMBASE and Chinese Biomedical Literature Database were searched and all randomized controlled trials of axillary dissection in old women (at least 60 years old) were considered. Meta-analyses were completed using RevMan5.1. Results: Three eligible randomized controlled trials (RCTs) including 5,337 patients were considered. There was weak evidence in favour of axillary dissection (AD) in old women. The meta-analysis showed that the overall survival (OS) after 1, 3, 5 and 7 years and the disease free survival (DFS) after 1, 3 and 5 year were not statistically significantly different between AD and no AD groups. However, there was a difference in the 7 year DFS. Conclusions: Axillary dissection did not provide survival benefit to the old women with breast cancer analysed. Therefore, axillary dissection is not well-indicated in old women with breast cancer.

• 논리연구
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• 제8권2호
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• pp.33-58
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• 2005

오래된 증거의 문제는 가설이 제안되기 이전에 이미 알려진 증거는 그 가설을 입증할 수 없다는 문제를 제기한다. 오래진 증거의 문제는 베이즈적 입증 개념에 심각한 문제를 제기하는데 그것은 관련 학자들의 많은 노력에도 불구하고 여전히 미해결의 상태로 남아있다. 이 글의 목적은 오래된 증거의 문제가 베이즈적 입증 개념에 대한 심각한 오해에서 비롯되었다는 점을 보임으로써 그 문제를 해결하는 것이다. 먼저 논의의 출발점인 오래된 증거의 문제가 분석되고 이어서 베이즈주의자들이 그 문제를 해갈하기 위해서 제안한 두 가지의 대표적 입장이 비판적으로 검토된다. 이러한 과정을 통하여 오래된 증거의 문제에 대한 기존의 논의들에서 공통적으로 발견되는 오해, 즉 설명과 예측의 맥락에서 나타나는 입증의 비대칭성이 무시되는 현상이 지적된다. 마지막으로 입증의 비대칭성을 이용하여 두 종류의 구별되는 베이즈적 입증 개념이 제시되고 오래된 증거의 문제에서 가정된 입증은 진정한 입증이 아니라는 점이 주장된다.

• 논리연구
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• 제15권1호
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• pp.107-154
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• 2012

이전 논문(2009)에서 나는 잠자는 미녀 역설에 대한 한 가지 해결책을 제시하였는데, 그에 의하면 미녀가 동전 앞면에 월요일에 부여하는 확률은 1/2보다 낮아야 한다. 이것은 물론 1/3주의에 유리한 결론이다. 그렇지만 내가 1/3주의를 성공적으로 옹호했다고 할지라도, 한 가지 중요한 물음이 남는다: 왜 1/2주의는 틀렸는가? 그들의 주요 논변은 간단하다: 잠자는 미녀는 동전이 어떻게 땅에 떨어지는지에 대한 새로운 증거를 받지 못했기 때문에, 그녀가 그 가능성에 부여하는 확률은 이전과 같아야 한다. 이제 다음 사실에 주목해 보자: 만일 1/3입장이 옳다면 잠자는 미녀 역설은 이른바 오래된 증거 문제의 새로운 예가 될 것이다. 이 논문에서 나는 새롭고 직접적으로 관련된 증거가 없음에도 왜 잠자는 미녀가 그녀의 믿음의 정도를 바꿀 수 있는지 대니얼 가버(1983)가 오래된 증거 문제에 대해 내놓은 해결책을 가지고 설명할 것이다.

• 대한수학회지
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• 제38권6호
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• pp.1157-1166
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• 2001

This paper answers some old questions about approximate similarity and raises new ones. We provide positive evidence and a technique for finding negative evidence on the question of whether approximate similarity is the equivalence relation generated by approximate equivalence and similarity.

• 한국영어학회지:영어학
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• 제4권2호
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• pp.117-149
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• 2004

The paper is to argue against the asymmetric CP-V2 analysis of Old English, according to which finite verbs invariably undergo movement into a clause-final T within subordinate clauses and reach the functional head C within main clauses. The asymmetric CP-V2 analysis, first of all, faces difficulty in explaining a wide range of post-verbal elements within subordinate clauses. To resolve the problem, the analysis has to abandon the obligatoriness of V-to-T movement or introduce various types of extraposition whose status is dubious as a legitimate syntactic operation. Obligatory V-to-T movement in Old English lacks conceptual justification as well. Crosslinguistic evidence reveals that morphological richness in verbal inflection cannot entail overt verb movement. Moreover, the operation is always string-vacuous under the asymmetric CP- V2 analysis and has no effect at the interfaces, in violation of the principle of economy. The distribution of Old English finite verbs in main clauses also undermines the asymmetric CP-V2 analysis. Conceptually speaking, a proper syntactic trigger cannot be confirmed to motivate obligatory verb movement to C. The operation not only gets little support from nominative Case marking, the distribution of expletives, or complementizer agreement but also requires the unconvincing stipulation that expletives as well as sentence-initial subjects result from string-vacuous topicalization. Finally, textual evidence testifies that Old English sometimes permits non-V2 ordering patterns, many of which remain unexplained under the asymmetric CP-V2 analysis.

• Journal of Chest Surgery
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• 제24권7호
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• pp.701-711
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• 1991

We experienced 6 cases of primary cardiac tumor, all received operation for removal of tumor. Mean age was 43.8 years-old ranging from 17 years-old to 66 years-old. Five cases were female, one case was male. Five cases were benign, myxoma, all located within left atrium. One case was malignant, angiosarcoma within right atrium. All patient showed cardiac manifestations. One case was in NYHA functional class II, two were in III, three were in IV. Four patients showed constitutional symptoms, but no one showed evidence of embolic phenomenon. All case of myxoma showed cardiomegaly except one malignancy. Only one case was regular sinus rhythm, three were sinus tachycardia 8z two were atrial fibrillation. The most common site of tumor origin was fossa ovalis limbus[four of all]. Two of five myxomas received emergency operation, one patient died postoperatively. Lived four patients showed no evidence of recurrence[mean follow-up, 3,5 years], but one patient has Grade II /IV mitral regurgitation & in OPD follow-up now, One malignant case, 17 years-old cerebral palsy female, was angiosarcoma occupied most of right atrial chamber originated from anterior wall of right atrium, received emergency operation which was removal of mass & reconstruction of right atrium with artificial pericardial patch. This patient died on postoperative 36th day due to persistent LCOS[low cardiac output syndrome] with combined sepsis.

• 지역사회간호학회지
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• 제17권3호
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• pp.315-325
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• 2006

Purpose: The Purpose of this study was to build up guidelines for preventing constipation in the Korean elderly based on the National Guideline $Clearinghouse^{TM}$ Guideline. Method: The process is composed of four steps: first. the composition of an expert group; second, the evaluation by the expert group about the appropriateness and applicability of each recommendation in the guideline; third, systematic literature review for evidence searching; and fourth. the formation of guidelines for Preventing constipation in the Korean elderly according to experts' opinions and literature review. Result: The appropriateness and applicability of each recommendation showed high scores, but the score of applicability was lower than that of appropriateness. The reasons for lower score of applicability were lack of cognition on the importance of constipation management and lack of recent information and evidence-based knowledge on constipation. There were some inadequate recommendations in Korean clinical setting. So the modified and replaced recommendations were added to the guidelines for preventing constipation in the old adult population to improve the applicability in Korea. Conclusion: The results of this study can be used as fundamental baseline data for future study to develope guidelines for management of constipation in the elderly and will be adapted locally for Korean clinical setting.

• Genomics & Informatics
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• 제7권2호
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• pp.131-135
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• 2009

Domains are the building blocks of proteins. Exon shuffling is an important mechanism accounting for combination of a limited repertoire of protein domains in the evolution of multicellular species. A relative excess of domains encoded by symmetric exons in metazoan phyla has been presented as evidence of exon shuffling, and symmetric domains can be divided into old and new domains by determining the ages of the domains. In this report, we compare the spread, versatility, and subcellular localization of old and new domains by analyzing eight metazoan genomes and their respective annotated proteomes. We found that new domains have been expanding as multicellular organisms evolved, and this expansion was principally because of increases in class 1-1 domains amongst several classes of domain families. We also found that younger domains have been expanding in membranes and secreted proteins along with multi-cellular organism evolution. In contrast, old domains are located mainly in nuclear and cytoplasmic proteins. We conclude that the increasing mobility and versatility of new domains, in contrast to old domains, plays a significant role in metazoan evolution, facilitating the creation of secreted and transmembrane multidomain proteins unique to metazoa.

• Radiation Oncology Journal
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• 제32권4호
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• pp.266-271
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• 2014

In the clinical state of oligometastases or oligorecurrence, a transitional state between localized and widespread systemic disease, local control of the disease may yield improved systemic control. Radiotherapy may be a good means for controlling oligometastatic tumors, particularly in very old patients for whom surgery may be infeasible. A combination of systemic therapy and local therapy is necessary to prevent systemic progression. Some kinds of cancers found in the elderly are known to be somewhat indolent for systemic progression. So, for very old patients who refuse or cannot tolerate chemotherapy, the use of radical radiotherapy alone to treat oligorecurrences may be very helpful. We successfully treated an 87-year-old patient who had been diagnosed with oligorecurrences three times over six years with radiotherapy alone. The patient is now, about four years after his first radiotherapy for liver metastasis, alive without any evidence of cancer and with fully active performance status.

• 대한가정학회지
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• 제49권10호
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• pp.57-69
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• 2011

The purpose of the present study was to examine married female immigrants' life style and marriage satisfaction on the perception of preparing their old age. We also investigated how socio-demographic factors influence their Preparation for old age. For the study, -data were collected from 350 questionnaires obtained from female immigrants living in Chungcheongnam-do. Cronbach's ${\alpha}$ tests were conducted for reliability, and regressional analysis was conducted to test our hypotheses. The results of this study shows that there is evidence of relations among the sub-variables. However, we found attitudes to safety and material pursuit are not related to married female immigrants' preparations for their old age. On the other hand, the results indicate that their life style and marriage satisfaction influences their perception of preparing their old age in a positive way. Finally, sociodemographic factors such as gender, age, education, marriage status, occupation and income are shown to affect the women's perception of preparing their old age positively.