• 약학회지
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• 제39권5호
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• pp.487-494
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• 1995

Solid lipid microspheres (SLMs) were prepared using various lipids and solidifying agents, in order to enhance the gastrointestinal absorption of Cyclosporine A (Cs A) which is a practically water-insoluble drug with low systemic bioavailability. Egg lecithin and HCO-60 (polyoxyethylated 60 mol, hydrogenated castor oil) were used as lipids. Stearic acid and stearyl alcohol were used as solidifying agents. Emulsion concentrates containing Cs A were prepared by mixing the melted lipid and solidifying agent with water, employing bile salts as a cosurfactant. SLMs were obtained by dispersing the warm emulsion concentrate in cold distilled water under mechanical stirring, followed by freeze drying. Physical characteristics of each SLM were investigated by particle size analysis, optical microscopy and scanning electron microscopy. Mean particle size of SLMs was in the range of 30 to 40.mu.m. The SLMs were in good appearance with spherical shape before freeze drying, but were deformed partially after freeze drying. Drug loading efficiencies of SLMs were observed as high as 80 to 90% in average. The systemic bioavailability of Cs A from different SLM formula was investigated in rats following oral administration. Cs A in whole blood was extracted and assayed by HPLC. SLMs revealed the higher bioavailabilities than the standard formula based on the marketed product. SLMs might have several advantages over standard formula for enhanced gastrointestinal absorption, controlled release properties, high loading capacity of the water-insoluble drug, and feasibility of solid dosage forms with better stability in storage.

• 한국식품영양과학회지
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• 제27권1호
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• pp.46-50
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• 1998

폐단백질을 활용하는 방도의 하나로 폐단백질자원으로부터 토양에서 분리한 Aspergillus sp. 균주가 생산하는 phytase를 이용하여 불용성 단백질의 분리 효율성을 높였으며 추출 단백질의 기능성을 살펴보았다. 참깨박에 함유되어 있는 불용성 형태의 단백질을 가용성 형태의 단백질로 용출시키기 위한 최적 pH, 최적 온도, 최적 처리시간과 최적 첨가효소량은 4.0~5.0, $50^{\circ}C$, 8~10시간, 120unit였고, 효소처리된 참깨박은 phytase 처리의 경우 대조구에 비해 기포형성력은 크게 증가하지 않았으나 기포안정성은 다소 증가하였다. 참깨박 단백질의 유화력은 다소의 유화력과 안정성의 증가가 관찰되었고, 유지흡착력과 수분흡착력은 대조구에 비해서 높은 값을 나타내었다.

• 한국축산식품학회지
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• 제39권2호
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• pp.296-308
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• 2019

Although the yellow mealworm (Tenebrio molitor L.) is a promising alternative protein source, the effects of processing conditions on functional properties are unclear. In this study, a protein extract of yellow mealworm larvae (PEYM) was subjected to different heat temperature ($55^{\circ}C$, $75^{\circ}C$, and $95^{\circ}C$) with different time (20, 40, and 60 min) to evaluate the functional properties and protein oxidation. Different heat temperature treatment significantly affected the exposure of surface hydrophobicity of the proteins and protein molecule aggregation, which reached maximum levels at $95^{\circ}C$ for 60 min. Protein oxidation was inversely proportional to the temperature. Both the highest carbonyl value (1.49 nmol/mg protein) and lowest thiol value (22.94 nmol/mg protein) were observed at $95^{\circ}C$ for 60 min. The heating time-temperature interaction affected several functional properties, including solubility, emulsifying potential, and gel strength (GS). Solubility decreased near the isoelectric point (pH 5 to 6). As the temperature and heating time increased, emulsifying properties decreased and GS increased. The oil absorption capacity and foaming properties decreased and the water absorption capacity increased. These results confirmed that PEYM is a suitable source of proteins for processing and applications in the food industry.

• 한국식품저장유통학회지
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• 제30권3호
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• pp.419-433
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• 2023

Dried apple bugak, a traditional Korean dried food, was made using superfine powders of glutinous rice (GR), non-glutinous rice (NGR), and Wasabia koreana Nakai leaf (WKNL) as coating materials. This study aimed to determine the effect of coating sliced apples with superfine GR powders substitute with superfine NGR and WKNL powders at different ratios. Apple slices coated with superfine GR, NGR and WKNL powders were air-fried and compared with dried and air-fried apple bugak coated with superfine GR powders. The results showed that coating apple slices with superfine GR powders with the addition of superfine NGR and WKNL powders significantly increased oil absorption capacity and antioxidant activity but reduced viscosity, water absorption capacity, total polyphenol, total flavonoids contents, and improved color and structural improvements. Among all the samples, 80:20:5-treated (GR:NGR:WKNL) dried and air-fried bugak showed enhanced quality characteristics. Thus, the results suggested that coating apple slices by the substituting GR superfine rice powders with 10 or 20% of NGR and 3 or 5% of WKNL superfine powders produces good quality dried and air-fried bugak with nutritious characteristics.

• 한국식생활문화학회지
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• 제33권6호
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• pp.597-607
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• 2018

This study examined the nutrient components and measured the physicochemical properties of 23 Korean sweet potato cultivars. The proximate composition, free sugars, organic acids, and dietary fiber of sweet potato were analyzed and the water binding capacity, oil absorption and pasting characteristics were measured. The proximate composition was the highest in Happymi and was higher in colored sweet potato than in general sweet potato (p<0.05). The sucrose content was the highest among the free sugars in the general cultivars and yellow/orange colored cultivar. The major organic acids were oxalic acid, citric acid, malic acid, succinic acid, fumaric acid, and acetic acid. Oxalic acid and citric acid were high in the purple colored cultivars and malic acid was high in yellow/orange colored cultivars. Each total dietary fiber content of the general and colored cultivars was 7.51-13.94 and 13.04-16.97%, respectively, but there was no significant difference. The water binding capacity and oil absorption of Juhwangmi was high in all cultivars (p<0.05). The peak viscosity of sweet potato powder showed highest a significant difference of 12.50-1342 cP (p<0.05). The breakdown of Sincheonmi was 512, which was the highest value (p<0.05). The setback of Geonpungmi was significantly low, 6.0 (p<0.05).

• 한국식품과학회지
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• 제31권4호
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• pp.924-930
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• 1999

폐단백질을 활용하는 방도의 하나로 참깨박으로부터 불용성 단백질의 분리 효율성을 높이고 기능성을 개선하기 위하여 실온에서 5 kGy에서 20 kGy까지 방사선을 처리하였다. 조사선량 5 kGy에서 참깨박 단백질의 용출율은 최대를 나타내었으며 그 이상의 고선량에서는 용출율이 다소 감소하였다. 방사선처리된 참깨박단백질은 거품형성력과 거품안정성이 대조구에 비해 증가하였고, 유화력과 유화안정성도 방사선처리구가 비처리구에 비해 증가하였다. 수분흡착력은 별다른 변화가 없었으나, 유지흡착력은 방사선처리구가 비처리구에 비해 감소하였다.

• 한국식품과학회지
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• 제38권4호
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• pp.483-487
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• 2006

본 연구에서는 발아에 의해 콩의 단백질 용해도, 거품형성능, 유화력 및 유화안정성, 수분 및 유지 흡착력에 미치는 영향을 조사하였다. 발아콩분말은 $20^{\circ}C$에서 12, 24시간 동안 발아시킨 후 $60^{\circ}C$에서 24시간 건조하여 60 mesh로 마쇄하여 제조하였다. pH 2-12에서의 콩단백질의 용해도를 측정한 결과 pH 4에서 용해도가 가장 낮았으며, 그 이하, 이상의 pH에서는 증가하였다. 특히 pH 2와 10에서는 발아콩분말이 비발아콩분말보다 용해도가 낮게 나타났다. 거품형성능에 대한 발아의 영향을 조사한 결과는 pH 2와 12에서의 발아콩분말이 비발아콩분말보다 낮은 거품형성능을 나타낸 반면 30-120분간 정치시켜 측정한 거품안정성은 오히려 높았다. 콩분말의 각 pH 별 유화형성능 및 안정성을 알아본 결과 pH 10-12에서 발아콩분말이 비발아콩분말보다 값이 높았다. 수분흡착력은 발아에 의해 증가하였으나 유지흡착력은 감소하였다.

• 한국자원식물학회지
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• 제11권3호
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• pp.272-278
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• 1998

This study was carried out to investigate the functional properties such as nitrogen solubility, emulsifying property , foaming capapcity , water and oil absorption of Camellia (Camellia japonica .) seed protein isolate in condition of distilled water and 0.5M NaCl solution at pH 2.0∼10.0. Nitrogen solubility of Camellia protein isolate in distilled water showed the minimum value at pH 4.0 and increased at pH lower or higher than the isoelectric point(pH 4.0). It was 90.0 %at pH 10.0 Nitrogen solubility of 0.5M NaCl solution showed a similar pattern with that of distrille dwater but was higher than that of distilled water except pH 2.0 and pH 10.0. Emulsifying activity of Camellia seed protein islate showed the minimum value at pH 4.0, but was higher at ether value of pH. Emulsifying stability of protein isolate was stable by heat treatment for 30min, at 80℃ and increased in 0.5M NaCl solution more than that of distille dwater. Foaming capacity of Camellia seed protein isolate in distill3ed water showed the minimum value near the isoelectric point, While it changed little at other values of pH. Foaming stability slowly decreased as, but didn't make a significant difference as time was delayed . Oil absorption was 1.4ml per a sample of 1g and water absorption was 0.9ml per a sample of 1g. The former was higher than the latter . The content of total amino acid of Camellia protein isolate was 43.67% and the major total amino acid of Camellia protein isolate was 43.67% and the major total amino acid was in the order of glutamic acid , arginine, aspartic acid, and leucine.

• 한국식품영양학회지
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• 제36권4호
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• pp.264-273
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• 2023

Physicochemical properties and storage stability of plant-based alternative meat prepared with low-fat soybean powder (LPAM) treated by supercritical-CO₂ and those of full-fat soybean powder (FPAM) were compared. Ash and crude protein contents were higher in LPAM than in FRAM. Water absorption capacity and oil absorption capacity were significantly higher in LPAM than in FPAM. Water binding capacity was higher in LPAM than in FPAM during a 20 days storage period at 5℃ and pH was significantly lower in LPAM than in FPAM after a 5~10 days storage period. Hardness, gumminess and chewiness significantly increased with the increase in the storage period, and the three were significantly higher in LPAM than in FPAM after 10 days and 20 days of storage. The acid value showed no remarkable difference according to the storage period in LPAM; however, it was significantly higher in FPAM than in LPAM after 20 days of storage. The peroxide value and TBA value were significantly increased according to the storage period, and were significantly lower iin LPAM than in FPAM during all the storage periods. Therefore, the use of low-fat soybean powder may be effective in improving oxidative stability during storage in the production of plant-based alternative meat.

• 한국항해항만학회지
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• 제46권4호
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• pp.297-302
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• 2022

탄산칼슘과 염산 수용액에 폴리프로필렌 섬유를 침지시켜 표면에 염화칼슘 결정을 생성시킴으로써 발열 흡착포를 제작하였다. 발열 흡착포를 유출 기름으로 인해 유막이 형성된 해수면에 적용하면 염화칼슘 결정이 주변의 수분을 흡수하여 이온화되면서 용해열을 방출한다. 염화칼슘의 용해열을 유동점 이하의 저온에서 응고된 저유황 중질유를 액화시켜 흡유 가능한 상태로 전환시킨다. 발열 흡착포의 제작을 위해 폴리프로필렌 표면에 염화칼슘 결정을 생성시키기 위한 탄산칼슘과 염산의 최적 몰농도는 각각 0.25 M과 0.5 M이다. 저유황 중질유 발열 흡착포의 흡유능은 해수 온도에 따라 다르지만, 우리나라 인근 해역의 동절기 평균 수온인 10℃에서 4.5-7.08 g/g으로 매우 우수하였다. 염화칼슘 발열 흡착포를 사용하면 동절기 선박사고로 인하여 해양에 유출된 저유황 중질유를 효과적으로 흡유하여 제거할 수 있다.