• Journal of Preventive Medicine and Public Health
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• 제24권1호
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• pp.57-69
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• 1991

중심성 지방분포와 고혈압과의 관계와 비근 내측 피부두께가 기존의 말초성 지방분포를 나타내주는 삼두근 피부두께에 비해 더 우수한 지표가 되는지를 알아보기위해서 1990 년 해군수중 근무자 특수신체검사자 중에서 450 명을 연구자의 편의에 의해 추출되었다. 대상자의 평균 연령이 27.9 세였고 범위가 19-51세었다. 말초성 지방분포의 지표로 삼두근과 비골 내측 피부두께를, 중심성 지방분포는 견갑골하 피부두께와 이것과 삼두근으로 이루어진 비와 차이로 측정을 했다. 신체의 지방분포를 나타내는 피부두께와 이 들을 기준으로한 비와 차이의 지수를 4 분위수로 나누어 첫 1/4 분위수를 기준으로 하고 나머지 3 가지 수준을 기준에 비교를 했다. 연령과 전체적인 비만도를 다중지수분석으로 통제를 한 후 고혈압과의 관계에서 견갑골하 피부두께가 기준인 1/4 분위수와 비교해 보아 2/4, 3/4, 4/4 분위수로 증가함에 따라 각각 2.05(95 % 신뢰구간 1.18-3.59), 2.02(1.06-3.86), 4.00 (1.99-8.06) 의 유병비차비를 보였다. 견갑골하 피부두께와 비골 내측 피부두께의 차이 역시 4/4 분위수가 되었을 때만 2.45 (1.28-4.68)의 비차비를 보였다. 그 외의 삼근 피부두께와 비근내측 피부두께에서는 기준에 비교해 보아 1 을 포함하지 않은 비차비는 없었다. 연령과 전체적인 비만도를 조정한 비차비는 조정치 않은 조비차비에 비해 대체적으로 조금 감소했다. 비근 내측의 피부두께는 삼두근 피부두께에 비교해보아 더 우수한 말초성 지방분포를 대표해주는 피부두께로 보였다. 이러한 결과는 전체적인 비만도 수준과는 독립적으로 견갑골하 피부두께로 측정된 중심성 지방분포가 고협압과 관계가 있으며 우수한 중심성 지방분포를 나타내주는 지표가 됨을 시사해주는 소견이다.

• 대한영양사협회학술지
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• 제25권2호
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• pp.83-104
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• 2019

Elevated high-sensitivity C reactive protein (hs-CRP) levels and metabolic syndrome are considered important predictors of cardiovascular mortality. This study examined the influence of the alcohol consumption level on the hs-CRP level and the prevalence of metabolic syndrome in South Koreans. The study subjects were 3,884 participants (${\geq}19$ years) from the KNHANES in 2015. The subjects were divided into four groups according to their alcohol consumption; None (none-alcohol consumption), Low (less than 15 g/day), Medium (15~29.9 g/day), and High (over than 30 g/day). The odds ratio for high-risk hs-CRP of men was significantly lower in the Low or Medium groups compared to the None group. In women, the odds ratio for high-risk hs-CRP was not decreased in the Low or Medium groups but was significantly higher in the High group than in the None group. Compared to nondrinkers, the prevalence of metabolic syndrome was lower in the Low group and Medium group in both men and women, whereas it was significantly higher in the High group in men only. In particular, the prevalence of low HDL-cholesterol was lower in all drinking groups. When the confounding factors were adjusted, the odds ratio for low HDL-cholesterol appeared to decline in the Low groups in both men and women. On the other hand, in the Medium group, women showed an elevated odds ratios of high blood pressure (HBP) and high fasting plasma glucose but men showed an elevated odds ratios of HBP and high triglyceride levels. The overall results suggest that low alcohol consumption is more appropriate than medium alcohol consumption. Nevertheless, more study will be needed to evaluate the appropriate alcohol consumption level.

• Asian Pacific Journal of Cancer Prevention
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• 제16권15호
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• pp.6243-6247
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• 2015

Background: Thyroid cancer (TC) is a more common endocrine malignancy in females and is a major cause of death in developing countries. Therefore the aim of this study was to explore possible risk factors of thyroid cancer in females of Pakistan. Materials and Methods: This study covered 232 females, including 127 (54.7%) cases and 105 (45.2%) controls, from the INMOL Hospital and Sheikh Zayed Hospital, Lahore. Different risk factors were explored by the descriptive and inferentially statistics. Odds ratios and 95% confidence intervals for different risk factors were computed using logistic regression. Results: The results showed six risk factors, marital status, family history of thyroid cancer, iodine in the diet, oxidative stress, fast food and fried food, to demonstrate positive significant links to thyroid cancer (odds ratios and 95% confidence intervals of :2.152, 1.104-4.198; 2.630, 1.416-4.887; 2.391, 1.282-4.458; 4.115, 2.185-7.750; 3.656, 1.851-7.223; 2.357, 1.268-4.382; and 2.360, 1.199-4.643, respectively). Conclusions: The Oxidative stress, marital status, family history of cancer, fast food, use of iodine diet and fried food are the risk factors of thyroid cancer in females.

• 한국융합학회논문지
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• 제10권7호
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• pp.295-301
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• 2019

본 연구는 2013-2015년도 국민건강영양조사 원시자료를 활용하여 한국노인의 음주 및 흡연과 치주질환의 관련성을 평가하고자 하였다. 분석 결과, 비음주, 비흡연군에 비해 음주, 흡연군(odds ratio[OR] 1.50; 95% confidence interval[CI], 1.00-2.24)에서 치주질환 교차비가 유의하게 높았다. 치주질환 교차비는 음주와 흡연을 전혀 하지 않은 노인에 비해 음주와 흡연을 동시에 하는 노인에서 유의하게 높았다. 본 연구를 통해 음주 및 흡연은 치주질환과 유의한 관련성이 있음을 확인하였다. 따라서 노인의 구강건강유지를 위해 절주와 금연교육을 강화해야 할 것으로 판단된다.

• Journal of Korean Biological Nursing Science
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• 제25권1호
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• pp.32-42
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• 2023

Purpose: This study aimed to investigate the association between obesity and high-sensitivity C-reactive protein (hs-CRP) levels in Korean adults without cardiovascular disease (CVD). Methods: The subjects were 3,634 adults, and data were extracted from the seventh Korea National Health and Nutrition Examination Survey (KNHANES VII-3). A complex sampling design analysis was applied to reflect the stratified and clustered weights. The data were analyzed using the complex sample Rao-Scott chi-square test and multiple logistic regression analysis (in SPSS for Windows version 26.0). Obesity, according to body mass index (BMI), was defined as obesity (BMI = 25-29.9 kg/m²), high obesity (BMI = 30-34.9 kg/m²), and super-high obesity (BMI ≥ 35 kg/m²), and abdominal obesity (AO) was defined as a waist circumference (WC) ≥ 90 cm in males and WC ≥ 85 cm in females. Results: The odds ratios for moderate CVD risk (hs-CRP; 1-3 mg/dL) were 2.21, 4.16, and 7.13 in the obesity, high obesity, and super-high obesity groups, respectively, compared to the normal BMI group. The odds ratio for moderate CVD risk was 2.18 in males with AO and 1.88 in females with AO. The odds ratios for high CVD risk (hs-CRP > 3 mg/L) were 4.40 and 17.55 in the high obesity and super-high obesity groups, respectively, compared to the normal BMI group. Conclusion: This study provides evidence that early detection and prevention programs for CVD should include obesity-related interventions aiming to modulate hs-CRP.

• 응용통계연구
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• 제34권2호
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• pp.225-238
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• 2021

이진분류모형의 성능을 탐색하는 시각적인 대표적인 방법인 ROC 곡선과 TOC 곡선 그리고 TROC 곡선은 혼동행렬을 구성하는 TP, TN, FP, FN 그리고 이들의 비율인 TPR, TNR, FPR, FNR으로 구현된다. 본 연구에서는 두 종류의 비율비인 오즈를 고려하여 단위면적인 정사각형에서의 구현하는 오즈 곡선을 제안하고, ROC 곡선과의 관계를 보인다. 오즈 곡선에서 판별력을 측정하는 두 종류의 측도를 제안하고, 오즈 곡선들의 형태를 바탕으로 두 종류의 측도를 이용하여 두 분류 분포의 판단 기준을 설정한다. 본 연구에서 제안한 오즈 곡선은 다른 시각적인 방법 등과 같이 유용하게 사용할 수 있으며, 오즈 곡선의 판별력을 측정하는 두 종류의 측도들은 분류 성능을 판단하는 대안적인 방법으로 같이 이용할 수 있다.

• Asian Pacific Journal of Cancer Prevention
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• 제14권5호
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• pp.3105-3108
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• 2013

Background: This study used National Health and Nutrition Examination Survey III to study the relationship between blood lead concentration and all cause, all cancer and lung cancer mortality in adults. Patients and Methods: Public use National Health and Nutrition Examination Survey (NHANES III) data were used. NHANES III uses stratified, multistage probabilistic methods to sample nationally representative samples. Household adult, laboratory and mortality data were merged. Sample persons who were available to be examined in aMobile Examination Center (MEC) were included in this study. Specialized survey analysis software was used. Results: A total of 3,482 sample participants with complete information for all variables were included in this analysis. For all cause death, the odds ratios (S.E.) for statistically significant variables were body mass index, 1.03 (1.01-1.06); 1.01 (1.01-1.01); blood lead concentration, 1.05 (1.01-1.08); poverty income ratio, 0.823 (0.76-0.89); and drinking hard liquor, 1.01 (1.00-1.02). For all cancer mortality, the odds ratios (S.E.) of the statistically signigicant variables were: age, 1.01 (1.01-1.01); blood lead concentration, 1.07 (1.04-1.12), black race, using non-Hispanic white as reference, 1.69 (1.12-2.56); and smoking, 1.02 (1.01-1.04). For lung cancer mortality, the odds ratios (S.E.) of the statistically significant variables were: age, 1.01(1.01-1.01); blood lead concentration, 1.09 (1.05-1.13); Mexican Americans, using non-Hispanic white as refrence, 0.33 (0.129-0.850); other races, 1.80 (0.53-6.18); and smoking, 1.03 (1.02-1.05). Conclusion: Blood lead concentration correlated with all cause, all cancer, and lung cancer mortality in adults.

• 한국학교보건학회지
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• 제28권1호
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• pp.31-37
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• 2015

Purpose: The aim of this study is to investigate the relation of the unhealthy eating habit of high school students in Seoul with their school types. Methods: In cross-sectional study, secondary data was used, representative sample of 7,284 subjects, high school students in Seoul. Consumption rates of Ramyun, Fast-food, and a breakfast-skipping rate were compared by the gender, grade, and school type. Descriptive statistics, ${\chi}^2$ analysis, correlation, and multiple logistic regression were used for data analysis. Results: The odds ratios (OR) of associated factors on the breakfast-skipping were 1.25 times higher in the 11th grade, 1.26 times in the 12th grade (reference: 10th grade), 1.21 times in school for both gender (reference: only male gender), 2.63 times in the general high school, 4.82 times in the vocational (reference: the autonomous private). The odds ratios (OR) of associated factors on frequent Ramyun intake were 2.10 times in male, 1.79 times in both gender (reference: only male gender), 2.01 times in the general high school, vocational 5.26 times (reference: the autonomous private). The odds ratios (OR) of associated factors on frequent Fast-food intake were 1.89 times in school for both gender (reference: only male gender), 3.93 times in the vocational high school (reference: the autonomous private). Conclusion: Students of the vocational high school than those of the autonomous private had more and more the breakfast-skipping rate, and had more consumption rates of Ramyun and Fast-food. Therefore, in order to improve these problems, intervention for students, diversified school health policy as well as health education to right food intake consumption are needed.

• 보건의료산업학회지
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• 제13권3호
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• pp.149-162
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• 2019

Objectives: The purpose of this study was to identify differences in characteristics of the people who frequently drink alone between those in old-city regions and those in other regions in Busan, focusing on socio-demographic factors and the level of drinking according to the types of stress. Methods: The analysis confirmed the differences based on Busan Social Statistics Data in 2012, 2014, and 2016. Frequencies by each variable were presented, and ${\chi}^2$ and logistic regression analysis were also used in the analysis. Results: The residents of Busan showed higher odds ratios of "frequent drinking alone" when they felt considerably higher-than-normal levels of stress. In addition, in the residents of old-city regions, the odds ratios of those who frequently drank alone were not different between people who could easily relieve stress, who experienced economic stress, or who had relationship stress and people who did not. However, higher odds ratios of frequently drinking alone were reported when such participants felt some stress related to work, family, relationships, and so on. Conclusions: Interventions for the appropriate relief of stress caused by different reasons, as well as other stress-relieving methods, should be implemented for the people's benefits.

• Genomics & Informatics
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• 제18권3호
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• pp.27.1-27.12
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• 2020

The prevalence of early-onset type 2 diabetes (EOT2D) is increasing in Asian countries. Genome-wide association studies performed in European and various other populations have identified associations of numerous variants with type 2 diabetes in adults. However, the genetic component of EOT2D which is still unexplored could have similarities with late-onset type 2 diabetes. Here in the present study we aim to identify the association of variants with EOT2D in South Indian population. Twenty-five variants from 18 gene loci were genotyped in 1,188 EOT2D and 1,183 normal glucose tolerant subjects using the MassARRAY technology. We confirm the association of the HHEX variant rs1111875 with EOT2D in this South Indian population and also the association of CDKN2A/2B (rs7020996) and TCF7L2 (rs4506565) with EOT2D. Logistic regression analyses of the TCF7L2 variant rs4506565(A/T), showed that the heterozygous and homozygous carriers for allele 'T' have odds ratios of 1.47 (95% confidence interval [CI], 1.17 to 1.83; p = 0.001) and 1.65 (95% CI, 1.18 to 2.28; p = 0.006) respectively, relative to AA homozygote. For the HHEX variant rs1111875 (T/C), heterozygous and homozygous carriers for allele 'C' have odds ratios of 1.13 (95% CI, 0.91 to 1.42; p = 0.27) and 1.58 (95% CI, 1.17 to 2.12; p = 0.003) respectively, relative to the TT homozygote. For CDKN2A/2B variant rs7020996, the heterozygous and homozygous carriers of allele 'C' were protective with odds ratios of 0.65 (95% CI, 0.51 to 0.83; p = 0.0004) and 0.62 (95% CI, 0.27 to 1.39; p = 0.24) respectively, relative to TT homozygote. This is the first study to report on the association of HHEX variant rs1111875 with EOT2D in this population.