• Title/Summary/Keyword: Ocular surface

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The Study of the Ultrastructure on the Rigid Gas Permeable Contact Lenses (Rigid Gas Permeable Contact Lenses의 미세구조에 대한 연구)

  • Kim, Douk-Hoon
    • Journal of Korean Ophthalmic Optics Society
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    • v.3 no.1
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    • pp.259-262
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    • 1998
  • The Anterior surface and posterior surface of rigid gas permeable(RGP) contact lenses has been studied by scanning electron microscopy. Results point out that the ultrastructure of contact lenses surface was some different on the anterior and posterior surface of RGP. The Quantitative study of surface roughness suggest that the anterior surface was more smooth than the posterior surface. These results suggest that the materials characters appeared the contact lens surface. The morphology of the anterior and posterior surface have different, Maybe, these result have a manufacture processing of the contact lenses. But some surface appeared a foreign body particles.

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Effects of Acupuncture Therapy on Dry Eye Syndrome: 43 Case Series (안구건조증 환자 43례의 침치료 효과에 대한 임상적 연구)

  • Lee, Chang-Woo;Lee, Eun-Kyoung;Jeon, Ju-Hyun;Kim, Jung-Ho;Kim, Young-Il;Kim, Jung-Il
    • Journal of Acupuncture Research
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    • v.27 no.6
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    • pp.85-94
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    • 2010
  • Objectives : The aim of this study was to evaluate the effect of acupuncture therapy on dry eye syndrome. Methods : We investigated 43 cases of patients with dry eye syndrome. They were treated with acupuncture therapy twice or three times a week. Symptoms score, number of dry eye symptoms, Ocular surface disease index were compared between eyes before and after treatment to evaluate the efficacy of acupuncture therapy. Results : After 24 times treatment, symptom score, number of dry eye symptoms, Ocular surface disease index were significantly decreased. Conclusions : Acupuncture therapy was effective to improve symptoms of dry eye syndrome patients. There should be more observation about patients with dry eye syndrome and further study will be needed.

Visual Fatigue Study of Active Senior (액티브 시니어의 시각 피로도 연구)

  • Cho, Hyesuk;Na, Yoonhye;Sim, Youngbo;Lee, Jangwoo;Park, Kunwoo
    • The Journal of the Korea Contents Association
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    • v.18 no.8
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    • pp.18-26
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    • 2018
  • This study aimed to examine whether there was difference on visual fatigue between active seniors and young people, and to provide a guideline for appropriate computer use time for seniors. Blinking rate, maximal blinking interval, temperature of the ocular surface, visual fatigue questionnare were evaluated. The blinking rate, ocular surface temperature, visual fatigue showed significant change before and after the tasks. There was no difference between the two groups and thus, about 30-minute computer work appeared to be appropriate for seniors.

Effect of combined sodium hyaluronate and carboxymethyl cellulose on ocular surface in rat dry eye model

  • Moon, Jong-Gab;Ku, Sae-Kwang;Kwon, Young-Sam
    • Korean Journal of Veterinary Research
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    • v.56 no.3
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    • pp.155-160
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    • 2016
  • This study was conducted to evaluate three different mixed formulations of sodium hyaluronate (SH) and carboxymethyl cellulose (CMC) using a low-humidity air flow-induced rat dry eye model and determine the most suitable mixture. The total thickness of the cornea, corneal epithelial thickness, corneal stroma thickness, damaged corneal epithelium percentage region, thickness of the bulbar conjunctiva epithelium, number of goblet cells, goblet cell occupation percentage region, and damaged bulbar conjunctiva epithelium percentage region were measured by histomorphological evaluation. After 5 h exposure to drying airflow, the thickness of the cornea and conjunctiva was decreased with desquamation of the corneal and conjunctiva epithelium. However, these dry eye symptoms were markedly inhibited by treatment with the reference and test formulations. More favorable effects on decreased thickness were detected in response to the CMC than the SH. However, SH had a greater protective effect against corneal and conjunctiva epithelial damage. The application of a mixture of 0.1% SH and 0.2% CMC showed more favorable effects on the corneal and conjunctival damage and the stabilization of the ocular surface than SH or CMC alone.

A Study on Monitoring Techniques for Dermal Exposure to Hazardous Chemicals

  • Lee, Su-Gil;Lee, Nae-Woo
    • International Journal of Safety
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    • v.8 no.1
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    • pp.18-23
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    • 2009
  • Due to dermal exposure to hazardous chemicals causing potential adverse health symptoms through skin absorption, dermal monitoring has had an important role in assessing such exposure. This paper overviews comparatively a number of studies of dermal monitoring with different methodologies such as surface monitoring, skin wiping, skin washing, adhesive methods and tape stripping, fluorescence and infrared spectroscopy, skin patches, pads and clothing, video exposure monitoring and dermal exposure assessment toolkits and models. However, there is a lack of information on the relationship between exposure levels and adverse health symptoms. Therefore, more specific strategies for dermal exposure monitoring should be developed and standardized with further development of biological and ocular monitoring.

First Report of Two Diogenid Species of Hermit Crabs (Crustacea: Decapoda: Anomura) from Korea

  • Jung, Jibom;Kim, Won
    • Animal Systematics, Evolution and Diversity
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    • v.31 no.2
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    • pp.107-113
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    • 2015
  • Two diogenid hermit crab species, Dardanus lagopodes and Diogenes deflectomanus, are newly reported from Korea. Dardanus lagopodes is distinguished from the other species of genus Dardanus in Korea by having setae with cream-colored tips on the cephalothorax and the following characteristics: ocular peduncles somewhat longer than antennular peduncles, and the pereopod without a longitudinal sulcus and scute-like projections. Diogenes deflectomanus is similar to D. nitidimanus but can be distinguished by having the fixed finger of the left cheliped bent slightly downwardly and the following characteristics: slightly shorter ocular peduncle, elongated left cheliped with small granules on the surface, right cheliped without calcareous teeth on the cutting edge of the dactylus, and the minute spine of post-median margin of the telson is not well developed. The geographical distributions of these two species are extended by the present study. In particular, D. deflectomanus in the current study is the first report outside Chinese waters. Now, 20 species of the family Diogenidae are known in Korean waters.

A Study of Dermal and Ocular Exposure to Isocyanate-Based Paints in Crash Repair Workshops (차량수리업에서 사용하는 이소시안계 페인트에 의한 피부와 눈의 노출에 관한 연구)

  • Lee, Su-Gil;Pisaniello, Dino;Lee, Nae-Woo;Tkaczuk, Michael
    • Journal of the Korean Society of Safety
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    • v.24 no.6
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    • pp.72-78
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    • 2009
  • Exposure to HDI(hexamethylene di-isocyanate) commonly used in vehicle crash repair workshops remains a leading cause of occupational asthma. Although skin and eye contamination are considered as absorption routes, there are no occupational exposure standards for skin and ocular exposure. This is the reason why there are more empirical data should be provided. Therefore this study was to determine contamination levels of HDI on the skin, eyes, work surfaces, respirators and eye protectors. There was evidence of contamination on a variety of work surfaces, for example, door handles, bench top and spray gun, etc. A high proportion(47~80%) of skin wipe samples from neck, forehead, back hand, palm and wrist was positive for HDI contamination, even though spray time was relatively brief. The contamination levels from spraying inside spray booth were generally higher than outside booth due to poor work practices and inappropriate personal protective use like safety gloves. Apprentices had higher exposure levels than the qualified painters, likely due to lack of the recognition of safety and hygiene. The extent of contamination inside the PPE might provide an indication of the potential for respiratory & skin exposure and ocular exposure. Eye fluid samples from 4 out of 14 workers had the positive detection of HDI contamination, due to poor work practices like no or inappropriate eye protection. Considering the potential for dermal & ocular exposure to contribute to possible health symptoms including respiratory sensitization, the empirical data point to a need for improving work practices and appropriate PPE selection, use and maintenance.

Laboratory passage and characterization of an isolate of Toxoplasma gondii from an ocular patient in Korea

  • Chai, Jong-Yil;Lin, Aifen;Shin, Eun-Hee;Oh, Myoung-Don;Han, Eun-Taek;Nam, Ho-Woo;Lee, Soon-Hyung
    • Parasites, Hosts and Diseases
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    • v.41 no.3
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    • pp.147-154
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    • 2003
  • Toxoplasma gondii tachyzoites were isolated from the blood of an ocular patient, and have been successfully passaged in the laboratory, for over a year, by peritoneal inoculation in mice. The isolated parasite was designated the Korean Isolate-1 (KI-1) and its characteristics were compared with those of the RH strain, a well-known virulent strain originating from a child who suffered from encephalitis. The morphology, pathogenicity, infectivity and cell culture characteristics of the KI-1 were similar to those of the RH strain. Both RH and KI-1 antigens were detected by an anti-T gondii monoclonal antibody (mAb), Tg563, against the major surface protein SAG1 (30 kDa), whereas no reaction was observed against an anti-Neospora caninum mAb, 12B4. The KI-1 was confirmed as an isolate of T. gondii. A long-term laboratory maintenance and characterization of a local T gondii isolate is reported for the first time in the Republic of Korea.

Effect of Korean Red Ginseng supplementation on dry eye syndrome in glaucoma patients - A randomized, double-blind, placebo-controlled study

  • Bae, Hyoung Won;Kim, Ji Hyun;Kim, Sangah;Kim, Minkyo;Lee, Naeun;Hong, Samin;Seong, Gong Je;Kim, Chan Yun
    • Journal of Ginseng Research
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    • v.39 no.1
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    • pp.7-13
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    • 2015
  • Background: Many patients with glaucoma have difficulty using antiglaucoma eye drops because of dry eye symptom. In this prospective, randomized, double-blind, placebo-controlled study, we evaluated the effect of Korean Red Ginseng on dry eye syndrome in patients with glaucoma treated with antiglaucoma eye drops. Methods: Forty-nine participants were allocated to the Korean Red Ginseng (3 g/day; n = 24) or placebo (n = 25) groups for 8 weeks. Tear film stability, fluorescein corneal staining, conjunctival hyperemia, tear production, grade of meibomian gland dysfunction, and dry eye questionnaire (Ocular Surface Disease Index) were evaluated at baseline and on completion of the treatment. Results: Almost all patients displayed dry eye symptoms and signs at baseline. After the 8-week intervention, Korean Red Ginseng supplementation significantly improved the tear film stability and total Ocular Surface Disease Index score, as compared to placebo (p < 0.01). Conclusion: Korean Red Ginseng supplementation may provide an additional treatment option for dry eye and patients with glaucoma using antiglaucoma eye drops.

Evaluation of Tear Film Lipid Layer Thickness Measurements Obtained Using an Ocular Surface Interferometer in Nasolacrimal Duct Obstruction Patients

  • Lee, Sang Min;Chung, Sok Joong;Lew, Helen
    • Korean Journal of Ophthalmology
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    • v.32 no.6
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    • pp.445-450
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    • 2018
  • Purpose: To compare the tear film lipid layer thickness (LLT) between patients with incomplete nasolacrimal duct obstruction (NLDO) and normal controls and to analyze the changes in tear film LLT and blinking pattern after silicone tube intubation in NLDO patients. Methods: We reviewed the medical records of 68 eyes in 52 incomplete NLDO patients who underwent silicone tube intubation from January 2017 to July 2017. The LLT, blinking pattern, and Meibomian gland image were measured with the LipiView II ocular surface interferometer. The Meibomian gland drop-out ratio was measured using the polygon selection tool in the Image J program. Tear meniscus height, which is the other lacrimal indicator, was assessed with spectral-domain optical coherence tomography. Results: Tear meniscus height was significantly decreased after silicone tube intubation (p < 0.01). Preoperative minimum, maximum, and average LLT values were $62.4{\pm}24.0$, $86.7{\pm}17.9$, and $71.7{\pm}23.3nm$, respectively. Significant changes in the minimum, maximum, and average LLT ($74.8{\pm}23.6$, $98.8{\pm}11.0$, and $91.6{\pm}16.1nm$, respectively) were observed after silicone tube intubation (p < 0.001, p = 0.001, and p < 0.001). The partial blinking/total blinking ratio in 20 seconds and the Meibomian gland drop-out ratio showed no significant change after silicone tube intubation. Conclusions: Overall, the LLT was increased after silicone tube intubation. Silicone tube intubation may be helpful in maintaining LLT with a normalized of amount of tears.